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Ocular Immunology and Inflammation Volume 24, 2016 - Issue 2
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Review Article

Ocular Inflammation: Can It Be a Sign of Activity of Weber-Christian Disease? A Case Report and Review of Literature

Sara VerrilliOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy, Correspondence[email protected]
, MD,
Angela CiarnellaOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy,
, MD,
Bruno LaganàImmunology Unit, S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy, and
, MD,
Silvia CalafioreOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy
, MD,
Fabio GuglielmelliOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy
, MD,
Luisanna BasileOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy
, MD,
Maria Giulia MutoloOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy
, MD &
Santi Maria RecuperoOphthalmology Unit, NESMOS Department S. Andrea Hospital, Faculty of Medicine and Psychology, “Sapienza” University of Rome, Rome, Italy
, MD show all
Pages 223-226 | Received 04 May 2014, Accepted 16 Sep 2014, Published online: 17 Oct 2014

References

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  • Klien BA. Nodular nonsuppurative panniculitis (Weber-Christian syndrome) with relapsing uveitis. Am J Ophthalmol. 1959;48:730–734
  • Panush RS, Yonker RA, Dlesk A, et al. Weber-Christian disease: analysis of 15 cases and review of the literature. Medicine (Baltimore). 1985;64:181–191
  • Pfeifer V. Uber einen Fall von herdweiser Atrophie des subkutanen Fettgewebes. Deutsches Arch Klin Med (Leipzig). 1892;50:438–449
  • Weber FP. A case of relapsing non-suppurative nodular panniculitis, showing phagocytosis of subcutaneous fat-cells by macrophages. Br J Dermatol Syphilis (Oxford). 1925;37:301–311
  • Iwasaki T, Hamano T, Ogata A, et al. Successful tratment of a patient with febrile, lobular pannicultis (Weber-Christian disease) with oral cyclosporin A: implications for pathogenesis and therapy. Intern Med. 1999;38:612–614
  • Christian HA. Relapsing febrile nodular non suppurative panniculitis. Arch Intern Med (Chicago). 1928;42:338–351
  • Theobald GD. Chronic Iridocyclitis Associated with Non-suppurative Panniculitis. Washington, DC: Ocular Pathology Club; 1953
  • Law DH, Dobbs C. Weber-Christian disease. J. Tennessee MA. 1963;56:3--4
  • Cook JN, Kikkawa DO. Proptosis as the manifesting sign of Weber-Christian disease. Am J Ophthalmol. 1997;124:125–126
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  • Freedman J. Ocular pathology associated with the Weber Christian syndrome. Br J Ophthalmol. 1972;56:896–898
  • Ackerman AB, Mosher DT, Schwamm HA. Factitial Weber-Christian syndrome. JAMA. 1966;198:731
  • Hinata M, Someya T, Yoshizaki H, et al. Successful treatment of steroid-resistant Weber-Christian disease with biliary ductopenia using cyclosporine A. Rheumatology (Oxford). 2005;44:821–823
  • Mavrikakis I, Georgiadis T, Fragiadaki K, et al. Orbital lobular panniculitis in Weber-Christian disease: sustained response to anti-TNF treatment and review of the literature. Surv Ophthalmol. 2010;55:584–589
  • Hirasaki S, Murakami K, Kanamori T, et al. Weber-Christian disease developing into mediastinitis and pleuritis with massive pleural effusion. Intern Med. 2012;51:943–947
  • Miyasaka N. Steroid-resistant Weber-Christian disease. Intern Med. 1999;38:522
  • Aronson IK, West DP, Variakojis D, et al. Fatal panniculitis. J Am Acad Dermatol. 1985;12:535–551

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