Infertility and pregnancy loss in euthyroid women with thyroid autoimmunity

References

• Poppe K, Velkeniers B, Glinoer D. The role of thyroid autoimmunity in fertility and pregnancy. Nat Clin Pract Endocrinol Metab 2008;4:394–405.
   PubMed Web of Science ®Google Scholar
• Stagnaro-Green A, Roman SH, Cobin RH, el-Harazy E, Alvarez-Marfany M, Davies TF. Detection of at-risk pregnancy by means of highly sensitive assays for thyroid autoantibodies. JAMA 1990;264:1422–1425.
   PubMed Web of Science ®Google Scholar
• Stagnaro-Green A, Glinoer D. Thyroid autoimmunity and the risk of miscarriage. Best Pract Res Clin Endocrinol Metab 2004;18:167–181.
   PubMed Web of Science ®Google Scholar
• Prummel MF, Wiersinga WM. Thyroid autoimmunity and miscarriage. Eur J Endocrinol 2004;150:751–755.
   PubMed Web of Science ®Google Scholar
• Poppe K, Velkeniers B, Glinoer D. Thyroid disease and female reproduction. Clin Endocrinol (Oxf) 2007;66:309–321.
   PubMed Web of Science ®Google Scholar
• Kutteh WH. Autoimmune factors in assisted reproduction. Minerva Ginecol 2002;54:217–224.
   PubMedGoogle Scholar
• Kalro BN. Impaired fertility caused by endocrine dysfunction in women. Endocrinol Metab Clin North Am 2003;32:573–592.
   PubMedGoogle Scholar
• Ghazeeri GS, Kutteh WH. Autoimmune factors in reproductive failure. Curr Opin Obstet Gynecol 2001;13:287–291.
   PubMed Web of Science ®Google Scholar
• Wilson C, Elstein M, Eade OE, Lloyd R, Wright R. Smooth-muscle antibodies in infertility. Lancet 1975;2:1238–1239.
   PubMed Web of Science ®Google Scholar
• Roussev RG, Kaider BD, Price DE, Coulam CB. Laboratory evaluation of women experiencing reproductive failure. Am J Reprod Immunol 1996;35:415–420.
   PubMed Web of Science ®Google Scholar
• Geva E, Lessing JB, Lerner-Geva L, Azem F, Yovel I, Amit A. The presence of antithyroid antibodies in euthyroid patients with unexplained infertility and tubal obstruction. Am J Reprod Immunol 1997;37:184–186.
   PubMed Web of Science ®Google Scholar
• Kutteh WH, Yetman DL, Carr AC, Beck LA, Scott RT Jr. Increased prevalence of antithyroid antibodies identified in women with recurrent pregnancy loss but not in women undergoing assisted reproduction. Fertility and Sterility, 1999;71:843–848.
   PubMed Web of Science ®Google Scholar
• Kaider AS, Kaider BD, Janowicz PB, Roussev RG. Immunodiagnostic evaluation in women with reproductive failure. Am J Reprod Immunol 1999;42:335–346.
   PubMed Web of Science ®Google Scholar
• Reimand K, Talja I, Metsküla K, Kadastik U, Matt K, Uibo R. Autoantibody studies of female patients with reproductive failure. J Reprod Immunol 2001;51:167–176.
   PubMed Web of Science ®Google Scholar
• Poppe K, Glinoer D. Thyroid autoimmunity and hypothyroidism before and during pregnancy. Hum Reprod Update 2003;9:149–161.
   PubMed Web of Science ®Google Scholar
• Poppe K, Glinoer D, Van Steirteghem A, Tournaye H, Devroey P, Schiettecatte J, Velkeniers B. Thyroid dysfunction and autoimmunity in infertile women. Thyroid 2002;12:997–1001.
   PubMed Web of Science ®Google Scholar
• Abalovich M, Mitelberg L, Allami C, Gutierrez S, Alcaraz G, Otero P, Levalle O. Subclinical hypothyroidism and thyroid autoimmunity in women with infertility. Gynecol Endocrinol 2007;23:279–283.
   PubMed Web of Science ®Google Scholar
• Gerhard I, Becker T, Eggert-Kruse W, Klinga K, Runnebaum B. Thyroid and ovarian function in infertile women. Hum Reprod 1991;6:338–345.
   PubMed Web of Science ®Google Scholar
• Matarese G, De Placido G, Nikas Y, Alviggi C. Pathogenesis of endometriosis: natural immunity dysfunction or autoimmune disease? Trends Mol Med 2003;9:223–228.
   PubMed Web of Science ®Google Scholar
• Janssen OE, Mehlmauer N, Hahn S, Offner AH, Gärtner R. High prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Eur J Endocrinol 2004;150:363–369.
   PubMed Web of Science ®Google Scholar
• Carp HJ, Selmi C, Shoenfeld Y. The autoimmune bases of infertility and pregnancy loss. J Autoimmun 2012;38:J266–J274.
   PubMed Web of Science ®Google Scholar
• Kachuei M, Jafari F, Kachuei A, Keshteli AH. Prevalence of autoimmune thyroiditis in patients with polycystic ovary syndrome. Arch Gynecol Obstet 2012;285:853–856.
   PubMed Web of Science ®Google Scholar
• Grassi G, Balsamo A, Ansaldi C, Balbo A, Massobrio M, Benedetto C. Thyroid autoimmunity and infertility. Gynecol Endocrinol 2001;15:389–396.
   PubMed Web of Science ®Google Scholar
• Poppe K, Glinoer D, Tournaye H, Devroey P, van Steirteghem A, Kaufman L, Velkeniers B. Assisted reproduction and thyroid autoimmunity: an unfortunate combination? J Clin Endocrinol Metab 2003;88:4149–4152.
   PubMed Web of Science ®Google Scholar
• van den Boogaard E, Vissenberg R, Land JA, van Wely M, van der Post JA, Goddijn M, Bisschop PH. Significance of (sub)clinical thyroid dysfunction and thyroid autoimmunity before conception and in early pregnancy: a systematic review. Hum Reprod Update 2011;17:605–619.
   PubMed Web of Science ®Google Scholar
• Singh A, Dantas ZN, Stone SC, Asch RH. Presence of thyroid antibodies in early reproductive failure: biochemical versus clinical pregnancies. Fertil Steril 1995;63:277–281.
   PubMed Web of Science ®Google Scholar
• Muller AF, Verhoeff A, Mantel MJ, Berghout A. Thyroid autoimmunity and abortion: a prospective study in women undergoing in vitro fertilization. Fertil Steril 1999;71:30–34.
   PubMed Web of Science ®Google Scholar
• Bussen S, Steck T, Dietl J. Increased prevalence of thyroid antibodies in euthyroid women with a history of recurrent in-vitro fertilization failure. Hum Reprod 2000;15:545–548.
   PubMed Web of Science ®Google Scholar
• Negro R, Mangieri T, Coppola L, Presicce G, Casavola EC, Gismondi R, Locorotondo G, et al. Levothyroxine treatment in thyroid peroxidase antibody-positive women undergoing assisted reproduction technologies: a prospective study. Hum Reprod 2005;20:1529–1533.
   PubMed Web of Science ®Google Scholar
• Glinoer D, Riahi M, Grün JP, Kinthaert J. Risk of subclinical hypothyroidism in pregnant women with asymptomatic autoimmune thyroid disorders. J Clin Endocrinol Metab 1994;79:197–204.
   PubMed Web of Science ®Google Scholar
• Poppe K, Glinoer D, Tournaye H, Schiettecatte J, Devroey P, van Steirteghem A, Haentjens P, Velkeniers B. Impact of ovarian hyperstimulation on thyroid function in women with and without thyroid autoimmunity. J Clin Endocrinol Metab 2004;89:3808–3812.
   PubMedGoogle Scholar
• Bagis T, Gokcel A, Saygili ES. Autoimmune thyroid disease in pregnancy and the postpartum period: relationship to spontaneous abortion. Thyroid. 2001;11:1049–1053.
   PubMed Web of Science ®Google Scholar
• American College of Obstetricians and Gynaecologists ACOG educational bulletin. Antiphospholipid syndrome. American College of Obstetricians and Gynaecologists. International Journal of Gynaecology and Obstetrics 1998;61:193–202.
   PubMedGoogle Scholar
• Natalia Lazzarin, Costanzo Moretti, Giovanna De Felice, Elena Vaquero, Dario Manfellotto. Further evidence on the Role of Thyroid autoimmunity in women with recurrent miscarriage. International Journal of Endocrinology 2012:717185.
   Google Scholar
• Twig G, Shina A, Amital H, Shoenfeld Y. Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity. J Autoimmun 2012;38:J275–J281.
   PubMed Web of Science ®Google Scholar
• Kwak-Kim JY, Chung-Bang HS, Ng SC, Ntrivalas EI, Mangubat CP, Beaman KD, Beer AE, Gilman-Sachs A. Increased T helper 1 cytokine responses by circulating T cells are present in women with recurrent pregnancy losses and in infertile women with multiple implantation failures after IVF. Hum Reprod 2003;18:767–773.
   PubMed Web of Science ®Google Scholar
• Raghupathy R, Makhseed M, Azizieh F, Omu A, Gupta M, Farhat R. Cytokine production by maternal lymphocytes during normal human pregnancy and in unexplained recurrent spontaneous abortion. Hum Reprod 2000;15:713–718.
   PubMed Web of Science ®Google Scholar
• Kim NY, Cho HJ, Kim HY, Yang KM, Ahn HK, Thornton S, Park JC, et al. Thyroid autoimmunity and its association with cellular and humoral immunity in women with reproductive failures. Am J Reprod Immunol 2011;65:78–87.
   PubMed Web of Science ®Google Scholar
• Pratt D, Novotny M, Kaberlein G, Dudkiewicz A, Gleicher N. Antithyroid antibodies and the association with non-organ-specific antibodies in recurrent pregnancy loss. Am J Obstet Gynecol 1993;168:837–841.
   PubMed Web of Science ®Google Scholar
• Lyden TW, Vogt E, Ng AK, Johnson PM, Rote NS. Monoclonal antiphospholipid antibody reactivity against human placental trophoblast. J Reprod Immunol 1992;22:1–14.
   PubMed Web of Science ®Google Scholar
• Di Simone N, Meroni PL, de Papa N, Raschi E, Caliandro D, De Carolis CS, Khamashta MA, et al. Antiphospholipid antibodies affect trophoblast gonadotropin secretion and invasiveness by binding directly and through adhered beta2-glycoprotein I. Arthritis Rheum 2000;43:140–150.
   PubMed Web of Science ®Google Scholar
• Cervera R, Balasch J. Bidirectional effects on autoimmunity and reproduction. Hum Reprod Update 2008;14:359–366.
   PubMed Web of Science ®Google Scholar
• Beer AE, Kwak JY, Ruiz JE. Immunophenotypic profiles of peripheral blood lymphocytes in women with recurrent pregnancy losses and in infertile women with multiple failed in vitro fertilization cycles. Am J Reprod Immunol 1996;35:376–382.
   PubMed Web of Science ®Google Scholar
• Aoki K, Kajiura S, Matsumoto Y, Ogasawara M, Okada S, Yagami Y, Gleicher N. Preconceptional natural-killer-cell activity as a predictor of miscarriage. Lancet 1995;345:1340–1342.
   PubMed Web of Science ®Google Scholar
• Emmer PM, Nelen WL, Steegers EA, Hendriks JC, Veerhoek M, Joosten I. Peripheral natural killer cytotoxicity and CD56(pos)CD16(pos) cells increase during early pregnancy in women with a history of recurrent spontaneous abortion. Hum Reprod 2000;15:1163–1169.
   PubMed Web of Science ®Google Scholar
• Ntrivalas EI, Kwak-Kim JY, Gilman-Sachs A, Chung-Bang H, Ng SC, Beaman KD, Mantouvalos HP, Beer AE. Status of peripheral blood natural killer cells in women with recurrent spontaneous abortions and infertility of unknown aetiology. Hum Reprod 2001;16:855–861.
   PubMed Web of Science ®Google Scholar
• Kelkar RL, Meherji PK, Kadam SS, Gupta SK, Nandedkar TD. Circulating auto-antibodies against the zona pellucida and thyroid microsomal antigen in women with premature ovarian failure. J Reprod Immunol 2005;66:53–67.
   PubMed Web of Science ®Google Scholar
• Toulis KA, Goulis DG, Venetis CA, Kolibianakis EM, Negro R, Tarlatzis BC, Papadimas I. Risk of spontaneous miscarriage in euthyroid women with thyroid autoimmunity undergoing IVF: a meta-analysis. Eur J Endocrinol 2010;162:643–652.
   PubMed Web of Science ®Google Scholar
• Toulis KA, Goulis DG, Venetis CA, Kolibianakis EM, Tarlatzis BC, Papadimas I. Thyroid autoimmunity and miscarriages: the corpus luteum hypothesis. Med Hypotheses 2009;73:1060–1062.
   PubMed Web of Science ®Google Scholar
• Csapo AI, Pulkkinen MO, Ruttner B, Sauvage JP, Wiest WG. The significance of the human corpus luteum in pregnancy maintenance. I. Preliminary studies. Am J Obstet Gynecol 1972;112:1061–1067.
   PubMed Web of Science ®Google Scholar
• Datta M, Roy P, Banerjee J, Bhattacharya S. Thyroid hormone stimulates progesterone release from human luteal cells by generating a proteinaceous factor. J Endocrinol 1998;158:319–325.
   PubMedGoogle Scholar
• Monteleone P, Parrini D, Faviana P, Carletti E, Casarosa E, Uccelli A, Cela V, et al. Female infertility related to thyroid autoimmunity: the ovarian follicle hypothesis. Am J Reprod Immunol 2011;66:108–114.
   PubMed Web of Science ®Google Scholar
• Szyper-Kravitz M, Marai I, Shoenfeld Y. Coexistence of thyroid autoimmunity with other autoimmune diseases: friend or foe? Additional aspects on the mosaic of autoimmunity. Autoimmunity 2005;38:247–255.
   PubMed Web of Science ®Google Scholar
• Inagaki J, Hao L, Nakatsuka M, Yasuda T, Hiramatsu Y, Shoenfeld Y, Matsuura E. A possible mechanism of autoimmune-mediated infertility in women with endometriosis. Am J Reprod Immunol 2011;66:90–99.
   PubMedGoogle Scholar
• Inagaki J, Kondo A, Lopez LR, Shoenfeld Y, Matsuura E. Pregnancy loss and endometriosis: pathogenic role of anti-laminin-1 autoantibodies. Ann N Y Acad Sci 2005;1051:174–184.
   PubMedGoogle Scholar
• Sinaii N, Cleary SD, Ballweg ML, Nieman LK, Stratton P. High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis. Hum Reprod 2002;17:2715–2724.
   PubMed Web of Science ®Google Scholar
• Petta CA, Arruda MS, Zantut-Wittmann DE, Benetti-Pinto CL. Thyroid autoimmunity and thyroid dysfunction in women with endometriosis. Hum Reprod 2007;22:2693–2697.
   PubMed Web of Science ®Google Scholar
• Hadfield R, Mardon H, Barlow D, Kennedy S. Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK. Hum Reprod 1996;11:878–880.
   PubMed Web of Science ®Google Scholar
• Kiprov DD, Nachtigall RD, Weaver RC, Jacobson A, Main EK, Garovoy MR. The use of intravenous immunoglobulin in recurrent pregnancy loss associated with combined alloimmune and autoimmune abnormalities. Am J Reprod Immunol 1996;36:228–234.
   PubMed Web of Science ®Google Scholar
• Sher G, Maassarani G, Zouves C, Feinman M, Sohn S, Matzner W, Chong P, Ching W. The use of combined heparin/aspirin and immunoglobulin G therapy in the treatment of in vitro fertilization patients with antithyroid antibodies. Am J Reprod Immunol 1998;39:223–225.
   PubMed Web of Science ®Google Scholar
• Stricker RB, Steinleitner A, Bookoff CN, Weckstein LN, Winger EE. Successful treatment of immunologic abortion with low-dose intravenous immunoglobulin. Fertil Steril 2000;73:536–540.
   PubMedGoogle Scholar
• Vaquero E, Lazzarin N, Valensise H, Menghini S, Di Pierro G, Cesa F, Romanini C. Pregnancy outcome in recurrent spontaneous abortion associated with antiphospholipid antibodies: a comparative study of intravenous immunoglobulin versus prednisone plus low-dose aspirin. Am J Reprod Immunol 2001;45:174–179.
   PubMed Web of Science ®Google Scholar
• Negro R, Formoso G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H. Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab 2006;91:2587–2591.
   PubMed Web of Science ®Google Scholar
• Poppe K, Velkeniers B. Female infertility and the thyroid. Best Pract Res Clin Endocrinol Metab 2004;18:153–165.
   PubMedGoogle Scholar
• Vissenberg R, van den Boogaard E, van Wely M, van der Post JA, Fliers E, Bisschop PH, Goddijn M. Treatment of thyroid disorders before conception and in early pregnancy: a systematic review. Hum Reprod Update 2012;18:360–373.
   PubMed Web of Science ®Google Scholar
• Reid SM, Middleton P, Cossich MC, Crowther CA. Interventions for clinical and subclinical hypothyroidism in pregnancy. Cochrane Database Syst Rev 2010 Jul 7;(7):CD007752.
   Google Scholar
• Abalovich M, Amino N, Barbour LA, Cobin RH, De Groot LJ, Glinoer D, Mandel SJ, Stagnaro-Green A. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2007;92:S1–47.
   PubMed Web of Science ®Google Scholar
• Horacek J, Spitalnikova S, Dlabalova B, Malirova E, Vizda J, Svilias I, Cepkova J, et al. Universal screening detects two-times more thyroid disorders in early pregnancy than targeted high-risk case finding. Eur J Endocrinol 2010;163:645–650.
   PubMed Web of Science ®Google Scholar
• Vaidya B, Anthony S, Bilous M, Shields B, Drury J, Hutchison S, Bilous R. Detection of thyroid dysfunction in early pregnancy: Universal screening or targeted high-risk case finding? J Clin Endocrinol Metab 2007;92:203–207.
   PubMed Web of Science ®Google Scholar
• Dosiou C, Barnes J, Schwartz A, Negro R, Crapo L, Stagnaro-Green A. Cost-effectiveness of universal and risk-based screening for autoimmune thyroid disease in pregnant women J Clin Endocrinol Metab 2012;97:1536–1546.
   PubMed Web of Science ®Google Scholar