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Exenatide

Exenatide improves ovarian and endometrial injury and preserves ovarian reserve in streptozocin induced diabetic rats

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Pages 196-201 | Received 21 Jul 2014, Accepted 08 Oct 2014, Published online: 04 Nov 2014

References

  • Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047–53
  • Kjaer K, Hagen C, Sando SH, Eshoj O. Epidemiology of menarche and menstrual disturbances in an unselected group of women with insulin-dependent diabetes mellitus compared to controls. J Clin Endocrinol Metab 1992;75:524–9
  • Isik S, Ozcan HN, Ozuguz U, et al. Evaluation of ovarian reserve based on hormonal parameters, ovarian volume, and antral follicle count in women with type 2 diabetes mellitus. J Clin Endocrinol Metab 2012;97:261–9
  • Yeshaya A, Orvieto R, Dicker D, et al. Menstrual characteristics of women suffering from insulin-dependent diabetes mellitus. Int J Fertil 1995;40:269–73
  • Whitworth KW, Baird DD, Stene LC, et al. Fecundability among women with Type 1 and Type 2 Diabetes in the Norwagian Mother and Child Cohort Study. Diabetologia 2011;54:516–22
  • Dorman JS, Steenkiste AR, Foley TP, et al. Familial Autoimmune and Diabetes (FAD) Study. Menopause in type 1 diabetic women: is it premature? Diabetes 2001;50:1857–62
  • Hoek A, Schoemaker J, Drexhage HA. Premature ovarian failure and ovarian autoimmunity. Endocrinol Rev 1997;18:102–34
  • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005;54:1615–25
  • Yamagishi S, Nakamura K, Imaizumi T. Advanced glycation end products (AGEs) and diabetic vascular complications. Curr Diabetes Rev 2005;1:93–106
  • Tatone C, Amicarelli F. The aging ovary-the poor granulosa cells. Fertil Steril 2013;99:12–17
  • Merhi Z. Advanced glycation end products and their relevance in female reproduction. Human Repr 2014;29:135–45
  • Piperi C, Adamopoulos C, Dalagiorgou G, et al. Crosstalk between advanced glycation and endoplasmic reticulum stress: emerging therapeutic targeting for metabolic diseases. J Clin Endocrinol Metab 2012;97:2231–42
  • Basta G. Receptor for advanced glycation endproducts and atherosclerosis: from basic mechanisms to clinical implications. Atherosclerosis 2008;196:9–21
  • Kalea AZ, Schmidt AM, Hudson BI. RAGE: a novel biological and genetic marker for vascular disease. Clin Sci (Lond) 2009;116:621–37
  • Barlovic DP, Soro-Paavonen A, Jandeleit-Dahm KAM. RAGE biology, atherosclerosis and diabetes. Clin Sci 2011;121:43–55
  • Nin JW, Jorsal A, Ferreira I, et al. Higher plasma sRAGE levels are associated with incident cardiovascular disease and all-cause mortality in Type 1 diabetes: a 12 year follow-up study. Diabetes 2010;59:2027–32
  • Sarkar G, Alattar M, Brown RJ, et al. Exenatide treatment for 6 months improves insülin sensitivity in adults with type 1 diabetes. Diabetes Care 2014;37:666–70
  • Wang D, Luo P, Li W, et al. Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism. Diabetes 2013;62:1697–708
  • Barakat GM, Nuwayri-Salti N, Kadi LN, et al. Role of glucagon-like peptide-1 and its agonists on early prevention of cardiac remodeling in type ! diabetic rat hearts. Gen Physiol Biophys 2011;30:34–44
  • Erbas O, Sarac F, Aktug H, Peker G. Detection of impaired cognitive function in rat with hepatosteatosis model and improving effect of GLP-1 analogs (exenatide) on cognitive function in hepatosteatosis. Scientific World J 2014. doi: 10.1155/2014/946265
  • Pala HG, Pala EE, Ulkumen AB, et al. The protective effect of granulocyte colony stimulating factor on endometrium and ovary in a rat model of diabetes mellitus. Gynecol Obstet Invest 2014;78:94–100
  • Bao W, Min D, Twigg SM, et al. Monocyte CD147 is induced by advanced glycation end products and high glucose concentration: possible role in diabetic complications. Am J Physiol Cell Physiol 2010;299:1212–19
  • Zhang F, Banker G, Liu X, et al. The novel function of advanced glycation end products in regulation of MMP-9 production. J Surg Res 2011;171:871–6
  • Kiriakidis S, Andreakos E, Monaco C, et al. VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2. J Cell Sci 2003;116:665–74
  • Pala HG, Erbas O, Oltulu F, et al. Glucose ınjury in diabetic rat's ovaries and effect of NF-kappa B way. Ege J Med 2013;52:32–6
  • Bierhaus A, Humpert PM, Morcos M, et al. Understanding RAGE, the receptor for advanced glycation end products. J Mol Med 2005;83:876–86
  • Jagannathan-Bogdan M, McDonnell ME, Shin H, et al. Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes. J Immunol 2011;186:1162–72
  • Epstein FH, Border WA, Noble NA. Transforming growth factor ß in tissue fibrosis. N Eng J Med 1994;331:1286–92
  • Karasu C. Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. Open Cardiovasc Med J 2010;4:240–56
  • Jang YY, Song JH, Shin YK, et al. Protective effect of boldine on oxidative mitochondrial damage in streptozotocin-induced diabetic rats. Pharmacol Res 2000;42:361–71
  • Nielsen F, Mikkelsen BB, Nielsen JB, et al. Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem 1997;43:1209–14
  • Bottazi B, Doni A, Garlanda C, Mantovani A. An integrated view of humoral innate immunity: pentraxins as a paradigm. Annu Rev Immunol 2010;28:157–83
  • Deban L, Russo RC, Sironi M, et al. regulation of leucocyte recruitment by the long pentraxin PTX3. Nat Immunol 2010;11:328–34
  • Garlanda C, Bottazzi B, Bastone A, Mantovani A. Pentraxıns at the crossroads between ınnate ımmunıty, ınflammatıon, matrıx deposıtıon, and female fertility. Annu Rev Immunol 2005;23:337–66
  • Yasunaga T, Ikeda S, Koga S, et al. Plasma pentraxin 3 is a more potent predictor of endothelial dysfunction than high-sensitive C-reaktive protein. Int Heart J 2014;55:160–4
  • Kaya C, Turgut H, Cengiz H, et al. Effect of detorsion alone and in combination with enoxaparin therapy on ovarian reserve and serum antimullerian hormone levels in a rat ovarian torsion model. Fertil Steril 2014;102:878–84
  • Soto N, Iñiguez G, López P, et al. Anti-Mullerian hormone and inhibin B levels as markers of premature ovarian aging and transition to menopause in type 1 diabetes mellitus. Hum Reprod 2009;24:2838–44
  • van Disseldorp J, Faddy MJ, Themmen AP, et al. Relationship of serum antimullerian hormone concentration to age at menopause. J Clin Endocrinol Metab 2008;93:2129–34
  • van Rooij IA, Broekmans FJ, Scheffer GJ, et al. Serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: a longitudinal study. Fertil Steril 2005;83:979–87
  • Garris DR. Diabetes (db/db) mutation-induced endometrial epithelial lipoapoptosis: ultrastructural and cytochemical analysis of reproductive tract atrophy. Reprod Biol Endocrinol 2005;3:15–26

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