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Original Article

Effect of local estrogen therapy (LET) on urinary and sexual symptoms in premenopausal women with interstitial cystitis/bladder pain syndrome (IC/BPS)

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Pages 828-832 | Received 29 Apr 2015, Accepted 14 Jun 2015, Published online: 31 Jul 2015

References

  • Hanno PM, Erickson D, Moldwin R, Faraday MM. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment. J Urol 2015;193:1545–53
  • Rudick CN, Pavlov VI, Chen MC, Klumpp DJ. Gender specific pelvic pain severity in neurogenic cystitis. J Urol 2012;187:715–24
  • Powell-Boone T, Ness TJ, Cannon R, et al. Menstrual cycle affects bladder pain sensation in subjects with interstitial cystitis. J Urol 2005;174:1832–6
  • Robbins A, Berkley KJ, Sato Y. Estrous cycle variation of afferent fibers supplying reproductive organs in the female rat. Brain Res 1992;596:353–6
  • Amandusson Å, Blomqvist A. Estrogenic influences in pain processing. Front Neuroendocrinol 2013;34:329–49
  • Parsons CL. The role of the urinary epithelium in the pathogenesis of interstitial cystitis/prostatitis/urethritis. Urology 2007;69:9–16
  • Acar D, Cayan S, Aktaş S, et al. The effect of tamoxifen on bladder functions and histology, and the role of estrogen receptor beta in a rat chemical cystitis model. Neurourol Urodyn 2007;26:309–16
  • Imamov O, Yakimchuk K, Morani A, et al. Estrogen receptor beta-deficient female mice develop a bladder phenotype resembling human interstitial cystitis. Proc Natl Acad Sci USA 2007;104:9806–9
  • Cabral C, Sampaio F, Cardoso L. Analysis of the modifications in the composition of bladder glycosaminoglycan and collagen as a consequence of changes in sex hormones associated with puberty or oophorectomy in female rats. J Urol 2003;170:2512–16
  • Portman DJ, Gass ML. Genitourinary syndrome of menopause: new terminology for vulvovaginal atrophy from the International Society for the Study of Women's Sexual Health and The North American Menopause Society. J Sex Med 2014;11:2865–72
  • Nappi RE, Davis SR. The use of hormone therapy for the maintenance of urogynecological and sexual health post WHI. Climacteric 2012;15:267–74
  • Gardella B, Porru D, Ferdeghini F, et al. Insight into urogynecologic features of women with interstitial cystitis/painful bladder syndrome. Eur Urol 2008;54:1145–51
  • Gardella B, Porru D, Nappi RE, et al. Interstitial cystitis is associated with vulvodynia and sexual dysfunction -- a case-control study. J Sex Med 2011;8:1726–34
  • Daha LK, Riedl CR, Hohlbrugger G, et al. Comparative assessment of maximal bladder capacity 0,9% NaCl vs. 0.2 M KCl, for the diagnosis of interstitial cystitis: a prospective controlled study. J Urol 2003;170:807–9
  • Nappi RE. New attitudes to sexuality in the menopause: clinical evaluation and diagnosis. Climacteric 2007;10:105–8
  • Van der Laak JA, Schijf CP, Kerstens HM, et al. Development and validation of a computerized cytomorphometric method to assess the maturation of vaginal epithelial cells. Cytometry 1999;35:196–202
  • Bachmann GA, Notelovitz M, Kelly SJ, et al. Long-term nonhormonal treatment of vaginal dryness. Clin Pract Sexual 1992; 8:12–17
  • Nappi RE, Albani F, Vaccaro P, et al. Use of the Italian translation of the Female Sexual Function Index (FSFI) in routine gynecological practice. Gynecol Endocrinol 2008;24:214–19
  • Wiegel M, Meston C, Rosen R. The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores. J Sex Marital Ther 2005;31:1–20
  • O'Leary MP, Sant GR, Fowler FJ, et al. The Interstitial Cystitis Symptom Index and Problem Index. Urology 1997;49:58–63
  • Brewer ME, White WM, Klein FA, et al. Validity of Pelvic Pain, Urgency, and Frequency questionnaire in patients with interstitial cystitis/painful bladder syndrome. Urology 2007;70:646–9
  • Nappi RE, Polatti F. The use of estrogen therapy in women's sexual functioning (CME). J Sex Med 2009;6:603–16
  • Vij M, Srikrishna S, Cardozo L. Interstitial cystitis: diagnosis and management Eur J Obstet Gynecol Reprod Biol 2012;161:1–7
  • Ungbhakorn P, Chalermsanyakorn P, Nilskulwat S, Kochakarn W. Estrogen and progesterone receptors in patients with bladder pain syndrome. J Med Assoc Thai 2013;96:302–6
  • Butrick CW. Interstitial cystitis and chronic pelvic pain: new insights in neuropathology, diagnosis, and treatment. Clin Obstet Gynecol 2003;46:811–23
  • Robbins MT, Mebane H, Ball CL, et al. Effect of estrogen on bladder nociception in rats. J Urol 2010; 83:1201–5
  • Ting AY, Blacklock AD, Smith PG. Estrogen regulates vaginal sensory and autonomic nerve density in the rat. Biol Reprod 2004;71:1397–404
  • Cheng Y, Keast JR. Effects of estrogens and bladder inflammation on mitogen-activated protein kinases in lumbosacral dorsal root ganglia from adult female rats. BMC Neurosci 2009;10:156
  • Bjorling DE, Wang ZY. Estrogen and neuroinflammation. Urology 2001;57:40–6
  • Warren JW, Clauw DJ, Wesselmann U, et al. Sexuality and reproductive risk factors for interstitial cystitis/painful bladder syndrome in women. Urology 2011;77:570–5
  • Burrows LJ, Goldstein AT. The treatment of vestibulodynia with topical estradiol and testosterone. Sex Med 2013;1:30–3
  • Goldstein AT, Belkin ZR, Krapf JM, et al. Polymorphisms of the androgen receptor gene and hormonal contraceptive induced provoked vestibulodynia. J Sex Med 2014;11:2764–71
  • Burrows LJ, Basha M, Goldstein AT. The effects of hormonal contraceptives on female sexuality: a review. J Sex Med 2012;9:2213–23
  • Greenstein A, Ben-Aroya Z, Fass O, et al. Vulvar vestibulitis syndrome and estrogen dose of oral contraceptive pills. J Sex Med 2007;4:1679–83
  • Salonia A, Clementi MC, Graziottin A, et al. Secondary provoked vestibulodynia in sexually active women with uncomplicated recurrent urinary tract infections. J Sex Med 2013;10:2265–73
  • Bosch PC. Examination of the significant placebo effect in the treatment of interstitial cystitis/bladder pain syndrome. Urology 2014;84:321–6
  • Bradford A. Listening to placebo in clinical trials for female sexual dysfunction. J Sex Med 2013;10:451–9
  • Davis NF, Brady CM, Creagh T. Interstitial cystitis/painful bladder syndrome: epidemiology, pathophysiology and evidence-based treatment options. Eur J Obstet Gynecol Reprod Biol 2014;175:30–7

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