352
Views
16
CrossRef citations to date
0
Altmetric
Irisin and PCOS

Irisin plasma concentration in PCOS and healthy subjects is related to body fat content and android fat distribution

, , , , , & show all
Pages 907-911 | Received 18 Feb 2015, Accepted 20 Jan 2015, Published online: 14 Jul 2015

References

  • Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev 1997;18:774–800
  • Gambineri A, Pelusi C, Vicennati V, et al. Obesity and the polycystic ovary syndrome. Int J Obes Relat Metab Disord 2002;26:883–96
  • Wild S, Pierpoint T, McKeigue P, Jacobs H. Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study. Clin Endocrinol (Oxf) 2000;52:595–600
  • Chen C-I, Hsu M-I, Lin S-H, et al. Adiponectin and leptin in overweight/obese and lean women with polycystic ovary syndrome. Gynecol Endocrinol 2015;31:264–8
  • Diamanti-Kandarakis E, Dunaif A. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr Rev 2012;33:981–1030
  • Souza Dos Santos AC, Soares NP, Costa EC, et al. The impact of body mass on inflammatory markers and insulin resistance in polycystic ovary syndrome. Gynecol Endocrinol Off J Int Soc Gynecol Endocrinol 2015;31:225–8
  • Pasquali R, Gambineri A, Pagotto U. The impact of obesity on reproduction in women with polycystic ovary syndrome. BJOG Int J Obstet Gynaecol 2006;113:1148–59
  • Spiegelman BM, Banting lecture 2012: regulation of adipogenesis: toward new therapeutics for metabolic disease regulation of adipogenesis. Diabetes 2013;62:1774–82
  • Jędrzejuk D, Laczmański L, Kuliczkowska J, et al. Selected CNR1 polymorphisms and hyperandrogenemia as well as fat mass and fat distribution in women with polycystic ovary syndrome. Gynecol Endocrinol 2015;31:36–9
  • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004;81:19–25
  • Alberti KGMM, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009;120:1640–5
  • Bednarek-Tupikowska G, Stachowska B, Miazgowski T, et al. Evaluation of the prevalence of metabolic obesity and normal weight among the Polish population. Endokrynol Pol 2012;63:447–55
  • Petrovic N, Walden TB, Shabalina IG, et al. Chronic Peroxisome proliferator-activated receptor γ (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes. J Biol Chem 2010;285:7153–64
  • Boström P, Wu J, Jedrychowski MP, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012;481:463–8
  • Klingenberg M, Huang S-G. Structure and function of the uncoupling protein from brown adipose tissue. Biochim Biophys Acta BBA – Biomembr 1999;1415:271–96
  • Hee Park K, Zaichenko L, Brinkoetter M, et al. Circulating irisin in relation to insulin resistance and the metabolic syndrome. J Clin Endocrinol Metab 2013;98:4899–907
  • Huh JY, Panagiotou G, Mougios V, et al. FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 2012;61:1725–38
  • Stengel A, Hofmann T, Goebel-Stengel M, et al. Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity – correlation with body mass index. Peptides 2013;39:125–30
  • Liu J-J, Wong MDS, Toy WC, et al. Lower circulating irisin is associated with type 2 diabetes mellitus. J Diabetes Comp 2013;27:365–9
  • Moon H-S, Dalamaga M, Kim S-Y, et al. Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. Endocr Rev 2013;34:377–412
  • Chang CL, Huang SY, Soong YK, et al. Circulating irisin and glucose-dependent insulinotropic peptide are associated with the development of polycystic ovary syndrome. J Clin Endocrinol Metab 2014;99:E2539–48
  • Walker GE, Marzullo P, Ricotti R, et al. The pathophysiology of abdominal adipose tissue depots in health and disease. Horm Mol Biol Clin Investig 2014;19:57–74
  • Ruderman NB, Schneider SH, Berchtold P. The “metabolically-obese,” normal-weight individual. Am J Clin Nutr 1981;34:1617–21
  • Gutierrez-Repiso C, Garcia-Serrano S, Rodriguez-Pacheco F, et al. FNDC5 could be regulated by leptin in adipose tissue. Eur J Clin Invest 2014;44:918–25
  • Lecker SH, Zavin A, Cao P, et al. Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure. Circ Heart Fail 2012;5:812–18
  • Wen M-S, Wang C-Y, Lin S-L, Hung K-C. Decrease in irisin in patients with chronic kidney disease. PLoS One 2013;8:e64025
  • Choi Y-K, Kim M-K, Bae KH, et al. Serum irisin levels in new-onset type 2 diabetes. Diabetes Res Clin Pract 2013;100:96–101
  • Moreno-Navarrete JM, Ortega F, Serrano M, et al. Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. J Clin Endocrinol Metab 2013;98:E769–78
  • Kuzmicki M, Telejko B, Lipinska D, et al. Serum irisin concentration in women with gestational diabetes. Gynecol Endocrinol 2014;30:636–9
  • Lemieux S, Prud'homme D, Bouchard C, et al. Sex differences in the relation of visceral adipose tissue accumulation to total body fatness. Am J Clin Nutr 1993;58:463–7
  • Lovejoy JC, Sainsbury A, Stock Conference 2008 Working Group. Sex differences in obesity and the regulation of energy homeostasis. Obes Rev 2009;10:154–67
  • Lee CC, Kasa-Vubu JZ, Supiano MA. Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women. Metabolism 2004;53:507–12

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.