373
Views
38
CrossRef citations to date
0
Altmetric
Research Article

Mean platelet volume and platelet distribution width in vascular dementia and Alzheimer’s disease

, , &
Pages 433-438 | Received 24 Jun 2013, Accepted 30 Jul 2013, Published online: 08 Oct 2013

References

  • de la Torre JC. Vascular risk factor detection and control may prevent Alzheimer’s disease. Ageing Res Rev 2010;9:218–225
  • Haag MD, Hofman A, Koudstaal PJ, Stricker BH, Breteler MM. Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study. J Neurol Neurosurg Psychiatry 2009;80:13–17
  • Borroni B, Agosti C, Marcello E, Di LM, Padovani A. Blood cell markers in Alzheimer Disease: Amyloid Precursor Protein form ratio in platelets. Exp Gerontol 2010;45:53–56
  • Farias G, Perez P, Slachevsky A, Maccioni RB. Platelet tau pattern correlates with cognitive status in Alzheimer’s disease. J Alzheimers Dis 2012;31:65–69
  • Forlenza OV, Wacker P, Nunes PV, Yacubian J, Castro CC, Otaduy MC, Gattaz WF. Reduced phospholipid breakdown in Alzheimer’s brains: A 31P spectroscopy study. Psychopharmacology (Berl) 2005;180:359–365
  • Johnston JA, Liu WW, Coulson DT, Todd S, Murphy S, Brennan S, Foy CJ, Craig D, Irvine GB, Passmore AP. Platelet beta-secretase activity is increased in Alzheimer’s disease. Neurobiol Aging 2008;29:661–668
  • Forlenza OV, Torres CA, Talib LL, de Paula VJ, Joaquim HP, Diniz BS, Gattaz WF. Increased platelet GSK3B activity in patients with mild cognitive impairment and Alzheimer’s disease. J Psychiatr Res 2011;45:220–224
  • Stellos K, Katsiki N, Tatsidou P, Bigalke B, Laske C. Association of platelet activation with vascular cognitive impairment: Implications in dementia development. Curr Vasc Pharmacol 2012;10:1–3
  • Laske C, Sopova K, Stellos K. Platelet activation in Alzheimer’s disease: From pathophysiology to clinical value. Curr Vasc Pharmacol 2012;10:626–630
  • Purandare N, Burns A. Cerebral emboli in the genesis of dementia. J Neurol Sci 2009;283:17–20
  • Purandare N, Burns A, Morris J, Perry EP, Wren J, McCollum C. Association of cerebral emboli with accelerated cognitive deterioration in Alzheimer’s disease and vascular dementia. Am J Psychiatry 2012;169:300–308
  • Sakurai H, Hanyu H, Sato T, Kume K, Hirao K, Kanetaka H, Iwamoto T. Effects of cilostazol on cognition and regional cerebral blood flow in patients with Alzheimer’s disease and cerebrovascular disease: A pilot study. Geriatr Gerontol Int 2013;13:90–97
  • Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: A link between thrombosis and inflammation. Curr Pharm Des 2011;17:47–58
  • Kaito K, Otsubo H, Usui N, Yoshida M, Tanno J, Kurihara E, Matsumoto K, Hirata R, Domitsu K, Kobayashi M. Platelet size deviation width, platelet large cell ratio, and mean platelet volume have sufficient sensitivity and specificity in the diagnosis of immune thrombocytopenia. Br J Haematol 2005;128:698–702
  • Wang RT, Li Y, Zhu XY, Zhang YN. Increased mean platelet volume is associated with arterial stiffness. Platelets 2011;22:447–451
  • Jans DM, Martinet W, Van De Parre TJ, Herman AG, Bult H, Kockx MM, De Meyer GR. Processing of amyloid precursor protein as a biochemical link between atherosclerosis and Alzheimer’s disease. Cardiovasc Hematol Disord Drug Targets 2006;6:21–34
  • Prodan CI, Ross ED, Stoner JA, Cowan LD, Vincent AS, Dale GL. Coated-platelet levels and progression from mild cognitive impairment to Alzheimer disease. Neurology 2011;76:247–252
  • Prodan CI, Szasz R, Vincent AS, Ross ED, Dale GL. Coated-platelets retain amyloid precursor protein on their surface. Platelets 2006;17:56–60
  • Prodan CI, Ross ED, Vincent AS, Dale GL. Differences in coated-platelet production between frontotemporal dementia and Alzheimer disease. Alzheimer Dis Assoc Disord 2009;23:234–237
  • Prodan CI, Ross ED, Vincent AS, Dale GL. Coated-platelets correlate with disease progression in Alzheimer disease. J Neurol 2007;254:548–549
  • Prodan CI, Ross ED, Vincent AS, Dale GL. Rate of progression in Alzheimer’s disease correlates with coated-platelet levels – a longitudinal study. Transl Res 2008;152:99–102
  • Salmina AB, Inzhutova AI, Malinovskaya NA, Petrova MM. Endothelial dysfunction and repair in Alzheimer-type neurodegeneration: neuronal and glial control. J Alzheimers Dis 2010;22:17–36
  • Gattaz WF, Cairns NJ, Levy R, Forstl H, Braus DF, Maras A. Decreased phospholipase A2 activity in the brain and in platelets of patients with Alzheimer’s disease. Eur Arch Psychiatry Clin Neurosci 1996;246:129–131
  • Krzystanek E, Krzystanek M, Opala G, Trzeciak HI, Siuda J, Malecki A. Platelet phospholipase A2 activity in patients with Alzheimer’s disease, vascular dementia and ischemic stroke. J Neural Transm 2007;114:1033–1039
  • Emmerling MR, Moore CJ, Doyle PD, Carroll RT, Davis RE. Phospholipase A2 activation influences the processing and secretion of the amyloid precursor protein. Biochem Biophys Res Commun 1993;197:292–297
  • Borkataky S, Jain R, Gupta R, Singh S, Krishan G, Gupta K, Kudesia M. Role of platelet volume indices in the differential diagnosis of thrombocytopenia: A simple and inexpensive method. Hematology 2009;14:182–186
  • Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, Mehler MF, Conway SJ, Ng LG, Stanley ER, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 2010;330:841–845
  • Boche D, Nicoll JA. The role of the immune system in clearance of Abeta from the brain. Brain Pathol 2008;18:267–278
  • Kaushansky K. Thrombopoietin. N Engl J Med 1998;339:746–754
  • Gomez RM, Moscato P. Identification of a 5-protein biomarker molecular signature for predicting Alzheimer’s disease. PLoS One 2008;3:e3111 . doi:10.1371/journal.pone.0003111
  • Lampron A, Gosselin D, Rivest S. Targeting the hematopoietic system for the treatment of Alzheimer’s disease. Brain Behav Immun 2011;25(Suppl 1):S71–S79
  • Wang RT, Jin D, Li Y, Liang QC. Decreased mean platelet volume and platelet distribution width are associated with mild cognitive impairment and Alzheimer’s disease. J Psychiatr Res 2013;47:644–649
  • Liu R, Gao F, Huo J, Yi Q. Study on the relationship between mean platelet volume and platelet distribution width with coronary artery lesion in children with Kawasaki disease. Platelets 2012;23:11–16

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.