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Original Article

Generalized scleroderma: response to colchicine therapy

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Page 100 | Published online: 12 Jul 2009

References

  • Alarcon-Segovia D, Ibanez G, Kershenobisch D, et al. Treatment of scleroderma by modification of collagen metabolism. A double blind trial of colchicine vs placebo. J Rheumatol 1974; 1(suppl)97
  • Alarcon-Segovia D, Kamos-Niembro F, Ibanez G, et al. Long term evaluation of colchicine in the treatment of scleroderma. J Rheumatol 1979; 6: 705–12
  • Malkinson F D. Colchicine, new uses of an old drug. Arch Dermatol 1982; 118: 453–7
  • Bauer E A, Valle K J. Colchicine induced stimulation of collagenase synthesis in normal human skin fibroblast cultures. Clin Res 1981; 29: 787A
  • Harris E D, Krane S M. Effect of colchicine on collagenase in culture of rheumatoid synovium. Arthritis Rheum 1971; 14: 669–84

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