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HYPOXIA REMOVES HRS

Low dose hyper-radiosensitivity is eliminated during exposure to cycling hypoxia but returns after reoxygenation

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Pages 311-319 | Received 29 Jun 2011, Accepted 28 Nov 2011, Published online: 06 Jan 2012

References

  • Bakkenist CJ, Kastan MB. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499–506.
  • Bartek J, Iggo R, Gannon J, Lane DP. 1990. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene 5:893–899.
  • Chen J. 2004. On the difference between reference radiations used in radiobiology. International Journal of Radiation Biology 80:577–580.
  • Chen J, Roos H, Kellerer AM. 2006. Radiation quality of photons in small and large receptors – a microdosimetric analysis. Radiation Protection Dosimetry 118:238–242.
  • Dey S, Spring PM, Arnold S, Valentino J, Chendil D, Regine WF, Mohiuddin M, Ahmed MM. 2003. Low-dose fractionated radiation potentiates the effects of Paclitaxel in wild-type and mutant p53 head and neck tumor cell lines. Clinical Cancer Research 9:1557–1565.
  • Edin NJ, Olsen DR, Stokke T, Pettersen EO. 2007. Recovery of low-dose hyper-radiosensitivity following a small priming dose depends on priming dose-rate. International Journal of Low Radiation 4:69–86.
  • Edin NJ, Sandvik JA, Olsen DR, Pettersen EO. 2009a. The elimination of low-dose hyper-radiosensitivity by transfer of irradiated-cell conditioned medium depends on dose rate. Radiation Research 171:22–32.
  • Edin NJ, Olsen DR, Stokke T, Sandvik JA, Ebbesen P, Pettersen EO. 2009b. Mechanisms of the elimination of low dose hyper-radiosensitivity in T-47D cells by low dose-rate priming. International Journal of Radiation Biology 85:1157–1165.
  • Elkind MM, Sutton-Gilbert H, Moses WB, Alescio T, Swain RW. 1965. Radiation response of mammalian cells grown in culture. V. Temperature dependence of the repair of X-ray damage in surviving cells (aerobic and hypoxic). Radiation Research 25:359–376.
  • Furre T, Bergstrand ES, Pedersen E, Koritzinsky M, Olsen DR, Hole EO, Pettersen EO. 1999. Measurement of dose rate at the interface of cell culture medium and glass dishes by means of ESR dosimetry using thin films of alanine. Radiation Research 152:76–82.
  • Gillespie CJ, Chapman JD, Reuvers AP, Dugle DL. 1975. The inactivation of Chinese hamster cells by X rays: Synchronized and exponential cell populations. Radiation Research 64:353–364.
  • Gray LH, Conger AD, Ebert M, Hornsey S, Scott OC. 1953. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. British Journal of Radiology 26:638–648.
  • Harney J, Short SC, Shah N, Joiner M, Saunders MI. 2004. Low dose hyper-radiosensitivity in metastatic tumors. International Journal of Radiation Oncology Biology Physics 59:1190–1195.
  • International Commission on Radiation Units and Measurement (ICRU). 1986. The quality factor in radiation protection. ICRU Report 40. Bethesda, MD: ICRU.
  • Joiner MC, Johns H. 1988. Renal damage in the mouse: The response to very small doses per fraction. Radiation Research 114:385–398.
  • Joiner MC, Marples B, Lambin P, Short SC, Turesson I. 2001. Low-dose hypersensitivity: Current status and possible mechanisms. International Journal of Radiation Oncology Biology Physics 49:379–389.
  • Joiner MC, Lambin P, Malaise EP, Robson T, Arrand JE, Skov KA, Marples B. 1996. Hypersensitivity to very-low single radiation doses: Its relationship to the adaptive response and induced radioresistance. Mutation Research 358:171–183.
  • Juan G, Traganos F, James WM, Ray JM, Roberge M, Sauve DM, Anderson H, Darzynkiewicz Z. 1998. Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis. Cytometry 32:71–77.
  • Kawrakow I. 2000. Accurate condensed history Monte Carlo simulation of electron transport. I. EGSnrc, the new EGS4 version. Medical Physics 27:485–498.
  • Kellerer AM, Roos H. 2005. Are all photon radiations similar in large absorbers? A comparison of electron spectra. Radiation Protection Dosimetry 113:245–250.
  • Koumenis C, Wouters BG. 2006. ‘Translating’ tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways. Molecular Cancer Research 4:423–436.
  • Krause M, Joiner M, Baumann M. 2003a. Ultrafractionation in human malignant glioma xenografts. International Journal of Cancer 107:333; author reply 334.
  • Krause M, Prager J, Wohlfarth J, Hessel F, Dorner D, Haase M, Joiner MC, Baumann M. 2005a. Ultrafractionation does not improve the results of radiotherapy in radioresistant murine DDL1 lymphoma. Strahlentherapie und Onkologie 181:540–544.
  • Krause M, Hessel F, Wohlfarth J, Zips D, Hoinkis C, Foest H, Petersen C, Short SC, Joiner MC, Baumann M. 2003b. Ultrafractionation in A7 human malignant glioma in nude mice. International Journal of Radiation Biology 79:377–383.
  • Krause M, Wohlfarth J, Georgi B, Pimentel N, Dorner D, Zips D, Eicheler W, Hessel F, Short SC, Joiner MC, . 2005b. Low-dose hyper-radiosensitivity of human glioblastoma cell lines in vitro does not translate into improved outcome of ultrafractionated radiotherapy in vivo. International Journal of Radiation Biology 81:751–758.
  • Krueger SA, Collis SJ, Joiner MC, Wilson GD, Marples B. 2007. Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity. International Journal of Radiation Oncology Biology Physics 69:1262–1271.
  • Lambin P, Marples B, Fertil B, Malaise EP, Joiner MC. 1993. Hypersensitivity of a human tumour cell line to very low radiation doses. International Journal of Radiation Biology 63:639–650.
  • Marples B, Joiner MC. 1993. The response of Chinese hamster V79 cells to low radiation doses: Evidence of enhanced sensitivity of the whole cell population. Radiation Research 133:41–51.
  • Marples B, Joiner MC. 1995. The elimination of low-dose hypersensitivity in Chinese hamster V79-379A cells by pretreatment with X rays or hydrogen peroxide. Radiation Research 141:160–169.
  • Marples B, Joiner MC, Skov KA. 1994. The effect of oxygen on low-dose hypersensitivity and increased radioresistance in Chinese hamster V79-379A cells. Radiation Research 138:S17–20.
  • Marples B, Wouters BG, Joiner MC. 2003. An association between the radiation-induced arrest of G2-phase cells and low-dose hyper-radiosensitivity: A plausible underlying mechanism? Radiation Research 160:38–45.
  • Millar BC, Fielden EM, Steele JJ. 1979. A biphasic radiation survival response of mammalian cells to molecular oxygen. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine 36:177–180. (Also, see correction vol. 36:433).
  • Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, . 1989. Mutations in the p53 gene occur in diverse human tumour types. Nature 342:705–708.
  • Pettersen EO, Larsen LH, Ramsing NB, Ebbesen P. 2005. Pericellular oxygen depletion during ordinary tissue culturing, measured with oxygen microsensors. Cell Proliferation 38:257–267.
  • Pettersen EO, Bjorhovde I, Sovik A, Edin NFJ, Zachar V, Hole EO, Sandvik JA, Ebbesen P. 2007. Response of chronic hypoxic cells to low dose-rate irradiation. International Journal of Radiation Biology 83:331–345.
  • Short SC, Kelly J, Mayes CR, Woodcock M, Joiner MC. 2001. Low-dose hypersensitivity after fractionated low-dose irradiation in vitro. International Journal of Radiation Biology 77:655–664.
  • Simonsson M, Qvarnstrom F, Nyman J, Johansson KA, Garmo H, Turesson I. 2008. Low-dose hypersensitive gamma H2AX response and infrequent apoptosis in epidermis from radiotherapy patients. Radiotherapy and Oncology 88:388–397.
  • Spring PM, Arnold SM, Shajahan S, Brown B, Dey S, Lele SM, Valentino J, Jones R, Mohiuddin M, Ahmed MM. 2004. Low dose fractionated radiation potentiates the effects of taxotere in nude mice xenografts of squamous cell carcinoma of head and neck. Cell Cycle 3:479–485.
  • Turesson I, Nyman J, Qvarnstrom F, Simonsson M, Book M, Hermansson I, Sigurdardottir S, Johansson KA. 2010. A low-dose hypersensitive keratinocyte loss in response to fractionated radiotherapy is associated with growth arrest and apoptosis. Radiotherapy and Oncology 94:90–101.
  • Wouters BG, Skarsgard LD. 1997. Low-dose radiation sensitivity and induced radioresistance to cell killing in HT-29 cells is distinct from the ‘adaptive response’ and cannot be explained by a subpopulation of sensitive cells. Radiation Research 148:435–442.
  • Xu B, Kim ST, Lim DS, Kastan MB. 2002. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Molecular and Cellular Biology 22:1049–1059.

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