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International Journal of Radiation Biology Volume 88, 2012 - Issue 10
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Research Article

Effect of 5-hydroxytryptamine (serotonin) receptor inhibitors on the radiation-induced bystander effect

Jennifer FazzariMcMaster Institute of Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada
,
Anna MersovMcMaster Institute of Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada
,
Richard SmithMcMaster Institute of Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada
,
Colin SeymourMcMaster Institute of Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada
&
Carmel MothersillMcMaster Institute of Applied Radiation Sciences, McMaster University, Hamilton, Ontario, CanadaCorrespondence[email protected]
Pages 786-790 | Received 08 Jun 2012, Accepted 18 Jul 2012, Published online: 09 Aug 2012

References

  • Berger M, Gray JA, Roth BL. 2009. The expanded biology of serotonin. Annual Review of Medicine 60:355–366.
  • Eglen R, Lee C, Smith W, Johnson LG, Whiting R, Hedge S. 1993. RS 42358-197, a novel and potent 5-HT3 receptor antagonist in vitro and in vivo. Journal of Pharmacology and Experimental Therapeutics 266:535–543.
  • Lohmann W, Moss AJ Jr, Sanders JL, Porter BJ, Woodall DM. 1966. Studies on the molecular mechanism of the radioprotective effect of serotonin. Radiation Research 29:155–165.
  • Lyng FM, Seymour CB, Mothersill C. 2002. Initiation of apoptosis in cells exposed to medium from the progeny of irradiated cells: A possible mechanism for bystander-induced genomic instability. Radiation Research 157:365–370.
  • Pirisi L, Creek KE, Doniger J, DiPaolo JA. 1988. Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA. Carcinogenesis 9:1573–1579.
  • Poon RC, Agnihotri N, Seymour C, Mothersill C. 2007. Bystander effects of ionizing radiation can be modulated by signaling amines. Environmental Research 105:200–211.
  • Mothersill C, Bucking C, Smith RW, Agnihotri N, O’Neill A, Kilemade M, Seymour CB. 2006. Communication of radiation-induced stress or bystander signals between fish in vivo. Environmental Science & Technology 40:6859–6864.
  • Mothersill C, Saroya R, Smith R, Singh H, Seymour B. 2010. Serum serotonin levels determine the magnitude and type of bystander effects in medium transfer experiments. Radiation Research 174: 119–123.
  • Raymond J, Turner J, Gelasco A, Ayiku H, Coaxum S, Arthur J, Garnovskaya M. 2006. 5-HT receptor signal transduction pathways. In: Roth B, editor. The serotonin receptors: From molecular pharmacology to human therapeutics. Totowa, NJ: Humana Press. Ch. 5.
  • Robertson JIS. 1988. Serotonin, serotonin antagonists, hypertension and vascular diseases. Current Opinion in Cardiology 3:702–714.
  • Saroya R, Smith R, Seymour C, Mothersill C. 2010. Injection of resperpine into zebrafish, prevents fish to fish communication of radiation-induced bystander signals: Confirmation in vivo of a role for serotonin in the mechanism. Dose Response 8:317–330.
  • Schulz M, Schmoldt A. 2003. Theraperutic and toxic blood concentrations of more then 800 drugs and xenobiotics. Pharmazie 58: 447–474.

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