Lymphocyte subsets and their H2AX phosphorylation in response to in vivo irradiation in rats

References

• Anderson RE, Warner NL. 1976. Ionizing radiation and the immune response. Advances in Immunology 24:215–335.
   PubMedGoogle Scholar
• Anderson RE, Olson GB, Autry JR, Howarth JL, Troup GM, Bartels PH. 1977. Radiosensitivity of T and B lymphocytes. IV. Effect of whole body irradiation upon various lymphoid tissues and numbers of recirculating lymphocytes. Journal of Immunology 118:1191–1200.
   Google Scholar
• Andrievski A, Wilkins RC. 2009. The response of gamma-H2AX in human lymphocytes and lymphocytes subsets measured in whole blood cultures. International Journal of Radiation Biology 85:369–376.
   PubMed Web of Science ®Google Scholar
• Bells L, Werbrouck J, Thierens H. 2010. Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation. International Journal of Radiation Biology 86:760–768.
   PubMedGoogle Scholar
• Bogdándi EN, Balogh A, Felgyinszki N, Szatmári T, Persa E, Hildebrandt G, Safrany G, Lumniczky K. 2010. Effects of low-dose radiation on the immune system of mice after total-body irradiation. Radiation Research 174:480–489.
   PubMed Web of Science ®Google Scholar
• Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, Bonner RF, Bonner WM, Nussenzweig A. 2003. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nature Cell Biology 5:675–679.
   PubMed Web of Science ®Google Scholar
• Chambers KA, Harrington NP, Ross WM, Filion LG. 1998. Relative alterations in blood mononuclear cell populations reflect radiation injury in mice. Cytometry 31:45–52.
   PubMedGoogle Scholar
• Clave E, Socie, G, Cosset JM, Chaillet MP, Tartour E, Girinsky T, Carosella E, Fridman H, Gluckman E, Mathiot C. 1995. Multicolor flow cytometry analysis of blood cell subsets in patients given total body irradiation before bone marrow transplantation. International Journal of Radiation Oncology Biology and Physics 33:881–886.
   PubMed Web of Science ®Google Scholar
• Dutreix J, Girinski T, Cosset JM, Bernard A, Pico J, Baume D, Bayle C, Benk V. 1987. Blood cell kinetics and total body irradiation. Radiotherapy and Oncology 9:119–129.
   PubMed Web of Science ®Google Scholar
• Girinsky T, Socie G, Cosset JM, Malaise EP. 1991. Blood lymphocyte subsets after the first fraction in patients given hyperfractionated total body irradiation for bone marrow transplantation. British Journal of Cancer 63:646–647.
   PubMed Web of Science ®Google Scholar
• Goodarzi AA, Jeggo PA. 2011. Irradiation induced foci (IRIF) as a biomarker for radiosensitivity. Mutation Research. [Epub ahead of print].
   PubMedGoogle Scholar
• Havelek R, Rezacova M, Sinkorova Z, Zarybnicka L, Tichy A, Vavrova J. 2011a. Phosphorylation of histone H2AX as an indicator of received dose of gamma radiation after whole-body irradiation of rats. Acta Veterinaria Brno 80:113–118.
   Google Scholar
• Havelek R, Rezacova M, Sinkorova Z, Zarybnicka L, Pejchal J, Vavrova J. 2011b. Phosphorylation of histone H2AX in peripheral blood mononuclear cells after thoracic irradiation of rats. Journal of Applied Biomedicine 9:209–218.
   Google Scholar
• Huang X, Darzynkiewicz Z. 2006. Cytometric assessment of histone H2AX phosphorylation: A reporter of DNA damage. Methods in Molecular Biology 314:73–80.
   PubMedGoogle Scholar
• Kataoka Y, Sado T. 1975. The radiosensitivity of T and B lymphocytes in mice. 1975. Immunology 29: 121–130.
   PubMedGoogle Scholar
• Löbrich M, Shibata A, Beucher A, Fisher A, Ensminger M, Goodarzi AA, Barton O, Jeggo PA. 2010. γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization. Cell Cycle 9:662–669.
   PubMed Web of Science ®Google Scholar
• Louagie H, Van Eijkeren M, Philippe J, Thierens H, De Ridder L. 1999. Changes in peripheral blood lymphocyte subsets in patients undergoing radiotherapy. International Journal of Radiation Biology 75:767–771.
   PubMed Web of Science ®Google Scholar
• Redon CE, Dickey JS, Bonner WM, Sedelnikova OA. 2009. γ-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin. Advances in Space Research 43:1171–1178.
   PubMed Web of Science ®Google Scholar
• Redon CE, Nakamura AJ, Gouliaeva K, Rahman A, Blakely WF, Bonner WM. 2011. Q(γ-H2AX), an analysis method for partial-body radiation exposure using γ-H2AX in nonhuman primate lymphocytes. Radiation Measurement 46:877–881.
   Google Scholar
• Rehakova Z, Sinkora J, Vlkova M, Vokurkova D, Osterreicher J, Vavrova J, Driak D. 2008. CD27(+) peripheral blood B-cells are a useful biodosimetric marker in vitro. Physiological Research 57: 589–600.
   PubMedGoogle Scholar
• Roch-Lefèvre S, Mandina T, Voisin P, Gaëtan G, Mesa JE, Valente M, Bonnesoeur P, Garcia O, Voisin P, Roy L. 2010. Quantification of gamma-H2AX foci in human lymphocytes: A method for biological dosimetry after ionizing radiation exposure. Radiation Research 174:185–194.
   Google Scholar
• Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. Journal of Biological Chemistry 273:5858–5868.
   PubMed Web of Science ®Google Scholar
• Rogakou EP, Boon C, Redon C, Bonner WM. 1999. Megabase chromatin domains involved in DNA double-strand breaks in vivo. Journal of Cell Biology 146:905–916.
   PubMed Web of Science ®Google Scholar
• Rothkamm K, Horn S. 2009. Gamma-H2AX as protein biomarker for radiation exposure. Annali Dell Instituto Superiore di Sanita 45: 265–271.
   PubMed Web of Science ®Google Scholar
• Schmitz A, Bayer J, Dechamps N, Thomas G. 2003. Intrinsic susceptibility to radiation-induced apoptosis of human lymphocyte subpopulations. International Journal of Radiation Oncology Biology and Physics 57:769–778.
   PubMed Web of Science ®Google Scholar
• Sinkorova Z, Sinkora J, Zarybnicka L, Vilasova Z, Pejchal J. 2009. Radiosensitivity of peripheral blood B cells in pigs. Veterinarni Medicina 54:223–235.
   Google Scholar
• Sinkorova Z, Zarybnicka L, Matoskova L, Tichy A, Pejchal J, Sinkora J. 2011. Dynamics of apoptosis in γ-irradiated lymphocytes and the CD21+ CD27+ B-cell subset as a potential biodosimetric marker. Radiation Measurement 46:1009–1013.
   Google Scholar
• Vokurkova D, Sinkora J, Vavrova J, Rezacova M, Knizek J, Osterreicher J. 2006. CD8+ natural killer cells have a potential of a sensitive and reliable biodosimetric marker in vitro. Physiological Research 55: 689–698.
   PubMedGoogle Scholar
• Vokurkova D, Vavrova J, Sinkora J, Stoklasova A, Blaha V, Rezacova M. 2010. Radiosensitivity of CD3-CD8+ CD56+ NK cells. Radiation Measurement 45:1020–3.
   Web of Science ®Google Scholar
• Wilkins RC, Wilkinson D, Maharaj HP, Bellier PV, Cybulski MB, McLean JR. 2002. Differential apoptotic response to ionizing radiation in subpopulations of human white blood cells. Mutation Research 513:27–36.
   PubMed Web of Science ®Google Scholar
• Zarybnicka L, Sinkorova Z, Sinkora J, Blaha V, Vavrova J, Pejchal J, Osterreicher J. 2011. Sensitivity of porcine peripheral blood leukocytes to gamma irradiation in vivo, in vitro and ex vivo. International Journal of Radiation Biology 87:491–498.
   PubMed Web of Science ®Google Scholar