Cyogenetics effects in AG01522 human primary fibroblasts exposed to low doses of radiations with different quality

References

• Anderson RM, Marsden SJ, Wright EG, Kadhim MA, Goodhead DT, Griffin CS. 2000. Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET alpha-particles. International Journal of Radiation Biology 76:31–42.
   PubMed Web of Science ®Google Scholar
• Anderson RM, Marsden SJ, Paice SJ, Bristow AE, Kadhim MA, Griffin CS, Goodhead DT. 2003. Transmissible and nontransmissible complex chromosome aberrations characterized by three-color and mFISH define a biomarker of exposure to high-LET alpha particles. Radiation Research 159:40–48.
   PubMed Web of Science ®Google Scholar
• Belli M, Cherubini R, Galeazzi G, Mazzuccato S, Moschini G, Sapora O, Simone G, Tabocchini, MA. 1987. Proton irradiation facility for radiobiological studies at a 7 MeV Van de Graaff accelerator. Nuclear Instruments and Methods in Physics Research A 256:476–480.
   Google Scholar
• Berardinelli F, Antoccia A, Cherubini R, De N, V, Gerardi S, Cirrone GA, Tanzarella C, Sgura A. 2010. Transient activation of the ALT pathway in human primary fibroblasts exposed to high-LET radiation. Radiation Research 174:539–549.
   PubMed Web of Science ®Google Scholar
• Berardinelli F, Antoccia A, Cherubini R, De N, V, Gerardi S, Tanzarella C, Sgura A. 2011. Telomere alterations and genomic instability in long-term cultures of normal human fibroblasts irradiated with X rays and protons. Radiation Protection Dosimetry 143:274–278.
   PubMed Web of Science ®Google Scholar
• Berardinelli F, Antoccia A, Buonsante B, Gerardi S, Cherubini R, De Nadal V, Tanzarella C, Sgura A. 2013. The role of telomere length modulation in delayed chromosome instability induced by ionizing radiation in human primary fibroblasts, Environmental and Molecular Mutagenesis 54:172–179.
   PubMed Web of Science ®Google Scholar
• Bolzan AD, Bianchi MS. 2006. Telomeres, interstitial telomeric repeat sequences, and chromosomal aberrations. Mutation Research 612:189–214.
   PubMed Web of Science ®Google Scholar
• Brenner DJ, Ward JF. 1992. Constraints on energy deposition and target size of multiply damaged sites associated with DNA double-strand breaks. International Journal of Radiation Biology 61:737–748.
   PubMed Web of Science ®Google Scholar
• Coleman MA, Yin E, Peterson LE, Nelson D, Sorensen K, Tucker JD, Wyrobek AJ. 2005. Low-dose irradiation alters the transcript profiles of human lymphoblastoid cells including genes associated with cytogenetic radioadaptive response. Radiation Research 164:369–382.
   PubMed Web of Science ®Google Scholar
• Cornforth MN. 2001. Analyzing radiation-induced complex chromosome rearrangements by combinatorial painting. Radiation Research 155:643–659.
   PubMed Web of Science ®Google Scholar
• d’Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP. 2003. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426:194–198.
   PubMed Web of Science ®Google Scholar
• de Lange T. 2002. Protection of mammalian telomeres. Oncogene 21:532–540.
   PubMed Web of Science ®Google Scholar
• Dugan LC, Bedford JS. 2003. Are chromosomal instabilities induced by exposure of cultured normal human cells to low- or high-LET radiation?Radiation Research 159:301–311.
   PubMed Web of Science ®Google Scholar
• Durante M, Furusawa Y, Gotoh E. 1998. A simple method for simultaneous interphase-metaphase chromosome analysis in biodosimetry. International Journal of Radiation Biology 74:457–462.
   PubMed Web of Science ®Google Scholar
• Hackett JA, Feldser DM, Greider CW. 2001. Telomere dysfunction increases mutation rate and genomic instability. Cell 106:275–286.
   PubMed Web of Science ®Google Scholar
• Hall EJ. 2003. The bystander effect. Health Physics 85:31–35.
   PubMed Web of Science ®Google Scholar
• Jeggo PA. 2009. Risks from low dose/dose rate radiation: What an understanding of DNA damage response mechanisms can tell us. Health Physics 97:416–425.
   PubMed Web of Science ®Google Scholar
• Joiner MC, Lambin P, Malaise EP, Robson T, Arrand JE, Skov KA, Marples B. 1996. Hypersensitivity to very-low single radiation doses: its relationship to the adaptive response and induced radioresistance. Mutation Research 358:171–183.
   PubMed Web of Science ®Google Scholar
• Joiner MC, Lambin P, Marples B. 1999. Adaptive response and induced resistance. Comptes Rendus de l’Académie des Sciences III 322:167–175.
   Web of Science ®Google Scholar
• Kadhim MA, Marsden SJ, Goodhead DT, Malcolmson AM, Folkard M, Prise KM, Michael BD. 2001. Long-term genomic instability in human lymphocytes induced by single-particle irradiation. Radiation Research 155:122–126.
   PubMed Web of Science ®Google Scholar
• Klokov D, Criswell T, Leskov KS, Araki S, Mayo L, Boothman DA. 2004. IR-inducible clusterin gene expression: A protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects. Mutation Research 568:97–110.
   PubMed Web of Science ®Google Scholar
• Krasavin EA, Govorun RD, Shmakova NL, Koshlan’ IV, Nasonova EA, Repin MV. 2004. Genetic action of radiation with different physical characteristics on mammalian cells. In: Kadyshevsky VG, editor. Physics of particles and nuclei. Pleiades Publishing. Vol. 35 pp 797–813.
   Google Scholar
• Lee R, Sommer S, Hartel C, Nasonova E, Durante M, Ritter S. 2010. Complex exchanges are responsible for the increased effectiveness of C-ions compared to X-rays at the first post-irradiation mitosis. Mutation Research 701:52–59.
   PubMed Web of Science ®Google Scholar
• Limoli CL, Corcoran JJ, Milligan JR, Ward JF, Morgan WF. 1999. Critical target and dose and dose-rate responses for the induction of chromosomal instability by ionizing radiation. Radiation Research 151:677–685.
   PubMed Web of Science ®Google Scholar
• Little JB. 1985. Mechanisms of malignant transformation of human diploid cells. Carcinogenesis: A Comprehensive Survey 10:337–353.
   PubMedGoogle Scholar
• Lo AW, Sabatier L, Fouladi B, Pottier G, Ricoul M, Murnane JP. 2002. DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 4:531–538.
   PubMed Web of Science ®Google Scholar
• Loucas BD, Cornforth MN. 2001. Complex chromosome exchanges induced by gamma rays in human lymphocytes: An mFISH study. Radiation Research 155:660–671.
   PubMed Web of Science ®Google Scholar
• Lucas JN. 1998. Cytogenetic signature for ionizing radiation. International Journal of Radiation Biology 73:15–20
   PubMed Web of Science ®Google Scholar
• Marples B, Joiner MC. 1993. The response of Chinese hamster V79 cells to low radiation doses: Evidence of enhanced sensitivity of the whole cell population. Radiation Research 133:41–51.
   PubMed Web of Science ®Google Scholar
• Marples B, Lambin P, Skov KA, Joiner MC. 1997. Low dose hyper-radiosensitivity and increased radioresistance in mammalian cells. International Journal of Radiation Biology 71:721–735.
   PubMed Web of Science ®Google Scholar
• Marples B, Joiner MC. 2000. Modification of survival by DNA repair modifiers: A probable explanation for the phenomenon of increased radioresistance. International Journal of Radiation Biology 76:305–312.
   PubMed Web of Science ®Google Scholar
• Marples B. 2004. Is low-dose hyper-radiosensitivity a measure of G2-phase cell radiosensitivity?Cancer and Metastasis Reviews 23:197–207.
   PubMed Web of Science ®Google Scholar
• Moore SR, Marsden S, Macdonald D, Mitchell S, Folkard M, Michael B, Goodhead DT, Prise KM, Kadhim MA. 2005. Genomic instability in human lymphocytes irradiated with individual charged particles: involvement of tumor necrosis factor alpha in irradiated cells but not bystander cells. Radiation Research 163:183–190.
   PubMed Web of Science ®Google Scholar
• Morgan WF. 2003. Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro. Radiation Research 159:567–580.
   PubMed Web of Science ®Google Scholar
• Morgan WF, Sowa MB. 2007. Non-targeted bystander effects induced by ionizing radiation. Mutation Research 616:159–164.
   PubMed Web of Science ®Google Scholar
• Mothersill C, Seymour C. 2001. Radiation-induced bystander effects: Past history and future directions. Radiation Research 155:759–767.
   PubMed Web of Science ®Google Scholar
• Mothersill C, Seymour C. 2004. Radiation-induced bystander effects and adaptive responses – the Yin and Yang of low dose radiobiology?Mutation Research 568:121–128.
   PubMed Web of Science ®Google Scholar
• Murnane JP, Sabatier L. 2004. Chromosome rearrangements resulting from telomere dysfunction and their role in cancer. Bioessays 26:1164–1174.
   PubMed Web of Science ®Google Scholar
• Murnane JP. 2010. Telomere loss as a mechanism for chromosome instability in human cancer. Cancer Research 70:4255–4259.
   PubMed Web of Science ®Google Scholar
• Nasonova EA, Shmakova NL, Komova OV, Mel'nikova LA, Fadeeva TA, Krasavin EA, Ritter S. 2006. Cytogenetic effects of low-dose radiation with different LET in human peripheral blood lymphocytes. Radiation and Environmental Biophysics 45:307–312.
   PubMed Web of Science ®Google Scholar
• Ojima M, Hamano H, Suzuki M, Suzuki K, Kodama S, Watanabe M. 2004. Delayed induction of telomere instability in normal human fibroblast cells by ionizing radiation. Journal of Radiation Research 45:105–110.
   PubMedGoogle Scholar
• Perner S, Bruderlein S, Hasel C, Waibel I, Holdenried A, Ciloglu N, Chopurian H, Nielsen KV, Plesch A, Hogel J, Moller P. 2003. Quantifying telomere lengths of human individual chromosome arms by centromere-calibrated fluorescence in situ hybridization and digital imaging. American Journal of Pathology 163:1751–1756.
   PubMed Web of Science ®Google Scholar
• Prise KM, Belyakov OV, Folkard M, Michael BD. 1998. Studies of bystander effects in human fibroblasts using a charged particle microbeam. International Journal of Radiation Biology 74:793–798.
   PubMed Web of Science ®Google Scholar
• Prise KM, Folkard M, Michael BD. 2003. A review of the bystander effect and its implications for low-dose exposure. Radiation Protection Dosimetry 104:347–355.
   PubMed Web of Science ®Google Scholar
• Prise KM. 2006. New advances in radiation biology. Occupational Medicine (Lond) 56:156–161.
   PubMed Web of Science ®Google Scholar
• Rugo RE, Secretan MB, Schiestl RH. 2002. X radiation causes a persistent induction of reactive oxygen species and a delayed reinduction of TP53 in normal human diploid fibroblasts. Radiation Research 158:210–219.
   PubMed Web of Science ®Google Scholar
• Savage JR, Simpson PJ. 1994. FISH ‘painting’ patterns resulting from complex exchanges. Mutation Research 312:51–60.
   PubMed Web of Science ®Google Scholar
• Slonina D, Biesaga B, Urbanski K, Kojs Z, Waligorski M. 2006. Evidence of low-dose hyper-radiosensitivity in normal cells of cervix cancer patients?Radiation Protection Dosimetry 122:282–284.
   PubMedGoogle Scholar
• Speicher MR, Gwyn BS, Ward DC. 1996. Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nature genetics 12:368–375.
   PubMed Web of Science ®Google Scholar
• Sprung CN, Afshar G, Chavez EA, Lansdorp P, Sabatier L, Murnane JP. 1999. Telomere instability in a human cancer cell line. Mutation Research 429:209–223.
   PubMedGoogle Scholar
• Suzuki K, Yamashita S. 2012. Low-dose radiation exposure and carcinogenesis. Japanese Journal of Clinical Oncology 42: 563–568.
   PubMed Web of Science ®Google Scholar
• Tsoulou E, Baggio L, Cherubini R, Kalfas CA. 2001. Low-dose hypersensitivity of V79 cells under exposure to gamma-rays and 4He ions of different energies: Survival and chromosome aberrations. International Journal of Radiation Biology 77:1133–1139.
   PubMed Web of Science ®Google Scholar
• Tsoulou E, Baggio L, Cherubini R, Kalfas CA. 2002. Radiosensitivity of V79 cells after alpha particle radiation at low doses. Radiation Protection Dosimetry 99:237–240.
   PubMedGoogle Scholar
• Wu H, Durante M, Furusawa Y, George K, Kawata T, Cucinotta FA. 2003. Truly incomplete and complex exchanges in prematurely condensed chromosomes of human fibroblasts exposed in vitro to energetic heavy ions. Radiation Research 160:418–424.
   PubMed Web of Science ®Google Scholar
• Yatagai F, Morimoto S, Goto S, Kato T, Honma M, Hanaoka F. 2002. Mutation induction in human cells after low dose X ray exposure. Radiation Protection Dosimetry 99:241–243.
   PubMedGoogle Scholar
• Zaichkina SI, Rozanova OM, Aptikaeva GF, Achmadieva AC, Klokov DY. 2004. Low doses of gamma-radiation induce nonlinear dose responses in mammalian and plant cells. Nonlinearity in Biology, Toxicology, and Medicine 2:213–221.
   PubMedGoogle Scholar