Low dose hypersensitivity following in vitro cell irradiation with charged particles: Is the mechanism the same as with X-ray radiation?

References

• Böhrnsen G, Weber KJ, Scholz M. 2002a. Low dose hypersensitivity and induced resistance of V79 cells after charged particle irradiation using 100 MeV/u carbon ions. Radiation Protection Dosimetry 99:255–256.
   PubMed Web of Science ®Google Scholar
• Böhrnsen G, Weber KJ, Scholz M. 2002b. Measurement of biological effects of high-energy carbon ions at low doses using a semi-automated cell detection system. International Journal of Radiation Biology 78:259–266.
   PubMed Web of Science ®Google Scholar
• Cherubini R, De Nadal V, Gerardi S. 2010. LNL Annual report: Bystander effect and hyper-radiosensitivity and induced radio-resistance in T98G glioblastoma cells after 28.5 keV/μm proton irradiation. Available from: http://www.lnl.infn.it/˜annrep/read_ar/2010/contributions/pdfs/151_B_71_B066.pdf
   Google Scholar
• Cherubini R, De Nadal V, Gerardi S, Guryev D. 2011. Lack of hyper- radiosensitivity and induced radioresistance and of bystander effect in V79 cells after proton irradiation of different energies. Radiation Protection Dosimetry 143:315–319.
   PubMed Web of Science ®Google Scholar
• Deckbar D, Birraux J, Krempler A, Tchouandong L, Beucher A, Walker S, Stiff T, Jeggo P, Löbrich M. 2007. Chromosome breakage after G2 checkpoint release. The Journal of Cell Biology 176: 749–755.
   PubMed Web of Science ®Google Scholar
• Edin NJ, Olsen DR, Sandvik JA, Malinen E, Pettersen EO. 2012. Low dose hyper-radiosensitivity is eliminated during exposure to cycling hypoxia but returns after reoxygenation. International Journal of Radiation Biology 88:311–319.
   PubMed Web of Science ®Google Scholar
• Enns L, Bogen KT, Wizniak J, Murtha AD, Weinfeld M. 2004. Low-dose radiation hypersensitivity is associated with p53-dependent apoptosis. Molecular Cancer Research 2:557–566.
   PubMed Web of Science ®Google Scholar
• Honore HB, Bentzen SM. 2006. A modelling study of the potential influence of low dose hypersensitivity on radiation treatment planning. Radiotherapy and Oncology 79:115–121.
   PubMed Web of Science ®Google Scholar
• Hooker AM, Bhat M, Day TK, Lane JM, Swinburne SJ, Morley AA, Sykes PJ. 2004. The linear no-threshold model does not hold for low-dose ionizing radiation. Radiation Research 162:447–452.
   PubMed Web of Science ®Google Scholar
• Joiner MC, Marples B, Lambin P, Short SC, Turesson I. 2001. Low-dose hypersensitivity: Current status and possible mechanisms. International Journal of Radiation Oncology Biology Physics 49:379–389.
   PubMed Web of Science ®Google Scholar
• Krueger SA, Collis SJ, Joiner MC, Wilson GD, Marples B. 2007a. Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity. International Journal of Radiation Oncology Biology Physics 69:1262–1271.
   PubMed Web of Science ®Google Scholar
• Krueger SA, Joiner MC, Weinfeld M, Piasentin E, Marples B. 2007b. Role of apoptosis in low-dose hyper-radiosensitivity. Radiation Research 167:260–267.
   PubMed Web of Science ®Google Scholar
• Krueger SA, Wilson GD, Piasentin E, Joiner MC, Marples B. 2010. The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity. International Journal of Radiation Oncology Biology Physics 77:1509–1517.
   PubMed Web of Science ®Google Scholar
• Ma CM, Luxton G, Orton CG. 2011. Point/counterpoint: Pulsed reduced dose rate radiation therapy is likely to become the treatment modality of choice for recurrent cancers. Medical Physics 38:4909–4911.
   PubMed Web of Science ®Google Scholar
• Marples B. 2004. Is low-dose hyper-radiosensitivity a measure of G2-phase cell radiosensitivity?Cancer and Metastasis Reviews 23:197–207.
   PubMed Web of Science ®Google Scholar
• Marples B, Joiner MC. 1993. The response of Chinese hamster V79 cells to low radiation doses: Evidence of enhanced sensitivity of the whole cell population. Radiation Research 133:41–51.
   PubMed Web of Science ®Google Scholar
• Marples B, Collis SJ. 2008. Low-dose hyper-radiosensitivity: Past, present, and future. International Journal of Radiation Oncology Biology Physics 70:1310–1318.
   PubMed Web of Science ®Google Scholar
• Marples B, Wouters BG, Joiner MC. 2003. An association between the radiation-induced arrest of G(2)-phase cells and low-dose hyper-radiosensitivity: A plausible underlying mechanism?Radiation Research 160:38–45.
   PubMed Web of Science ®Google Scholar
• Marples B, Lam GK, Zhou H, Skov KA. 1994. The response of Chinese hamster V79-379A cells exposed to negative pi-mesons: Evidence that increased radioresistance is dependent on linear energy transfer. Radiation Research 138(1 Suppl.):81–84.
   Web of Science ®Google Scholar
• Nasonova EA, Shmakova NL, Komova OV, Mel'nikova LA, Fadeeva TA, Krasavin EA, Ritter S. 2006. Cytogenetic effects of low-dose radiation with different LET in human peripheral blood lymphocytes. Radiation and Environmental Biophysics 45:307–312.
   PubMed Web of Science ®Google Scholar
• National Research Council (NRC). 2006. Health risks from exposure to low levels of ionizing radiation: BEIR VII Phase 2. Washington, DC: National Academies Press.
   Google Scholar
• Nikjoo H, O’Neill P, Terrissol M, Goodhead DT. 1999. Quantitative modelling of DNA damage using Monte Carlo track structure method. Radiation and Environmental Biophysics 38:31–38.
   PubMed Web of Science ®Google Scholar
• Nikjoo H, O’Neill P, Wilson WE, Goodhead DT. 2001. Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiation Research 156:577–583.
   PubMed Web of Science ®Google Scholar
• Ogawa Y, Takahashi T, Kobayashi T, Toda M, Nishioka A, Kariya S, Seguchi H, Yamamoto H, Yoshida S. 2003. Comparison of radiation-induced reactive oxygen species formation in adult articular chondrocytes and that in human peripheral T cells: Possible implication in radiosensitivity. International Journal of Molecular Medicine 11:455–459.
   PubMed Web of Science ®Google Scholar
• Park SS, Chunta JL, Robertson JM, Martinez AA, Oliver Wong CY, Amin M, Wilson GD, Marples B. 2011. MicroPET/CT imaging of an orthotopic model of human glioblastoma multiforme and evaluation of pulsed low-dose irradiation. International Journal of Radiation Oncology, Biology, Physics 80:885–892.
   PubMed Web of Science ®Google Scholar
• Pulkkanen K, Lahtinen T, Lehtimaki A, Joiner M, Kataja V. 2007. Effective palliation without normal tissue toxicity using low-dose ultrafractionated re-irradiation for tumor recurrence after radical or adjuvant radiotherapy. Acta Oncologica 46:1037–1041.
   PubMed Web of Science ®Google Scholar
• Raju MR. 1980. Heavy particle radiotherapy. New York: Academic Press.
   Google Scholar
• Rodel F, Keilholz L, Herrmann M, Sauer R, Hildebrandt G. 2007. Radiobiological mechanisms in inflammatory diseases of low-dose radiation therapy. International Journal of Radiation Biology 83:357–366.
   PubMed Web of Science ®Google Scholar
• Rothkamm K, Löbrich M. 2003. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low X-ray doses. Proceedings of the National Academy of Sciences of the USA 100:5057–5062.
   Google Scholar
• Schettino G, Folkard M, Prise KM, Vojnovic B, Bowey AG, Michael BD. 2001. Low-dose hypersensitivity in Chinese hamster V79 cells targeted with counted protons using a charged-particle microbeam. Radiation Research 156(5 Pt 1):526–534.
   PubMed Web of Science ®Google Scholar
• Scott BR. 2005. Stochastic thresholds: A novel explanation of nonlinear dose-response relationships for stochastic radiobiological effects. Dose Response 3:547–567.
   Google Scholar
• Semenenko VA, Stewart RD. 2006. Fast Monte Carlo simulation of DNA damage formed by electrons and light ions. Physics in Medicine and Biology 51:1693–1706.
   PubMed Web of Science ®Google Scholar
• Thomas C, Charrier J, Massart C, Cherel M, Fertil B, Barbet J, Foray N. 2008. Low-dose hyper-radiosensitivity of progressive and regressive cells isolated from a rat colon tumour: Impact of DNA repair. International Journal of Radiation Biology 84:533–548.
   PubMed Web of Science ®Google Scholar
• Tsoulou E, Baggio L, Cherubini R, Kalfas CA. 2001. Low-dose hypersensitivity of V79 cells under exposure to gamma-rays and He-4 ions of different energies: Survival and chromosome aberrations. International Journal of Radiation Biology 77:1133–1139.
   PubMed Web of Science ®Google Scholar
• Vaganay-Juery S, Muller C, Marangoni E, Abdulkarim B, Deutsch E, Lambin P, Calsou P, Eschwege F, Salles B, Joiner M, et al. 2000. Decreased DNA-PK activity in human cancer cells exhibiting hypersensitivity to low dose irradiation. British Journal of Cancer 83: 514–518.
   PubMed Web of Science ®Google Scholar
• Wera AC, Heuskin AC, Riquier H, Michiels C, Lucas S. 2013. Low-LET proton irradiation of A549 non-small cell lung adenocarcinoma cells: Dose response and RBE determination. Radiation Research 179:273–281.
   PubMed Web of Science ®Google Scholar
• Wouters BG, Sy AM, Skarsgard LD. 1996. Low-dose hypersensitivity and increased radioresistance in a panel of human tumor cell lines with different radiosensitivity. Radiation Research 146: 399–413.
   PubMed Web of Science ®Google Scholar
• Wykes SM, Piasentin E, Joiner MC, Wilson GD, Marples B. 2006. Low-dose hyper-radiosensitivity is not caused by a failure to recognize DNA double-strand breaks. Radiation Research 165:516–524.
   PubMed Web of Science ®Google Scholar
• Xu B, Kim ST, Lim DS, Kastan MB. 2002. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Molecular and Cellular Biology 22:1049–1059.
   PubMed Web of Science ®Google Scholar
• Xue L, Yu D, Furusawa Y, Cao J, Okayasu R, Fan S. 2009. ATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ions. International Journal of Radiation Oncology Biology Physics 75:235–243.
   PubMed Web of Science ®Google Scholar
• Ziegler JF, Biersack JP, Littmark U. 1985. The stopping and range of ions in solids. Oxford: Pergamon Press.
   Google Scholar