Effect of cell phone-like electromagnetic radiation on primary human thyroid cells

References

• Abu Khadra KM, Khalil AM, Abu Samak M, Aljaberi A. 2014. Evaluation of selected biochemical parameters in the saliva of young males using mobile phones. Electromagn Biol Med 34:72–76.
   PubMed Web of Science ®Google Scholar
• Agarwal A, Desai NR, Makker K, Varghese A, Mouradi R, Sabanegh E, Sharma R. 2009. Effects of radiofrequency electromagnetic waves (RF-EMW) from cellular phones on human ejaculated semen: An in vitro pilot study. Fertil Steril 92:1318–1325.
   PubMed Web of Science ®Google Scholar
• Al-Damegh MA. 2012. Rat testicular impairment induced by electromagnetic radiation from a conventional cellular telephone and the protective effects of the antioxidants vitamins C and E. Clinics (Sao Paulo) 67:785–792.
   PubMed Web of Science ®Google Scholar
• Bergamaschi A, Magrini A, Ales G, Coppeta L, Somma G. 2004. Are thyroid dysfunctions related to stress or microwave exposure (900 MHz)? Int J Immunopathol Pharmacol 17(2 Suppl.):31–36.
   PubMedGoogle Scholar
• Black DR, Heynick LN. 2003. Radiofrequency (RF) effects on blood cells, cardiac, endocrine, and immunological functions. Bioelectromagnetics Suppl. 6:S187–195.
   Google Scholar
• Bourthoumieu S, Magnaudeix A, Terro F, Leveque P, Collin A, Yardin C. 2013. Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells. Bioelectromagnetics 34:52–60.
   PubMed Web of Science ®Google Scholar
• Bourthoumieu S, Terro F, Leveque P, Collin A, Joubert V, Yardin C. 2011. Aneuploidy studies in human cells exposed in vitro to GSM-900 MHz radiofrequency radiation using FISH. Int J Radiat Biol 87:400–408.
   PubMed Web of Science ®Google Scholar
• Cam ST, Seyhan N. 2012. Single-strand DNA breaks in human hair root cells exposed to mobile phone radiation. Int J Radiat Biol 88:420–424.
   PubMed Web of Science ®Google Scholar
• Cardis E, Armstrong BK, Bowman JD, Giles GG, Hours M, Krewski D, McBride M, Parent ME, Sadetzki S, Woodward A, et al. 2011. Risk of brain tumours in relation to estimated RF dose from mobile phones: Results from five Interphone countries. Occup Environ Med 68:631–640.
   PubMed Web of Science ®Google Scholar
• Carlberg M, Hardell L. 2014. Decreased survival of glioma patients with astrocytoma grade IV (glioblastoma multiforme) associated with long-term use of mobile and cordless phones. Int J Environ Res Public Health 11:10790–10805.
   PubMed Web of Science ®Google Scholar
• Carlberg M, Hardell L. 2015. Pooled analysis of Swedish case-control studies during 1997–2003 and 2007–2009 on meningioma risk associated with the use of mobile and cordless phones. Oncol Rep 33:3093–3098.
   PubMed Web of Science ®Google Scholar
• Carvalho DP, Dupuy C. 2013. Role of the NADPH Oxidases DUOX and NOX4 in Thyroid Oxidative Stress. Eur Thyroid J 2:160–167.
   PubMedGoogle Scholar
• Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Ocak AR. 2009. Effect of mobile phone exposure on apoptotic glial cells and status of oxidative stress in rat brain. Electromagn Biol Med 28:342–354.
   PubMed Web of Science ®Google Scholar
• Deltour I, Auvinen A, Feychting M, Johansen C, Klaeboe L, Sankila R, Schuz J. 2012. Mobile phone use and incidence of glioma in the Nordic countries 1979–2008: Consistency check. Epidemiology 23:301–307.
   PubMed Web of Science ®Google Scholar
• de Souza FT, Silva JF, Ferreira EF, Siqueira EC, Duarte AP, Gomez MV, Gomez RS, Gomes CC. 2014. Cell phone use and parotid salivary gland alterations: No molecular evidence. Cancer Epidemiol Biomarkers Prev 23:1428–1431.
   PubMed Web of Science ®Google Scholar
• Duan Y, Zhang HZ, Bu RF. 2011. Correlation between cellular phone use and epithelial parotid gland malignancies. Int J Oral Maxillofac Surg 40:966–972.
   PubMed Web of Science ®Google Scholar
• Ellis R. Hematoxylin and Eosin Staining Protocol. Available at: http://www.ihcworld.com/_protocols/special_stains/h&e_ellis.htm. [accessed 26 Nov 26 2014].
   Google Scholar
• Enewold L, Zhu K, Ron E, Marrogi AJ, Stojadinovic A, Peoples GE, Devesa SS. 2009. Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980–2005. Cancer Epidemiol Biomarkers Prev 18:784–791.
   PubMed Web of Science ®Google Scholar
• Eskander EF, Estefan SF, Abd-Rabou AA. 2012. How does long term exposure to base stations and mobile phones affect human hormone profiles? Clin Biochem 45:157–161.
   PubMed Web of Science ®Google Scholar
• Esmekaya MA, Seyhan N, Omeroglu S. 2010. Pulse modulated 900 MHz radiation induces hypothyroidism and apoptosis in thyroid cells: A light, electron microscopy and immunohistochemical study. Int J Radiat Biol 86:1106–1116.
   PubMed Web of Science ®Google Scholar
• Feinmesser M, Tsabari C, Fichman S, Hodak E, Sulkes J, Okon E. 2003. Differential expression of proliferation- and apoptosis-related markers in lentigo maligna and solar keratosis keratinocytes. Am J Dermatopathol 25:300–307.
   PubMed Web of Science ®Google Scholar
• Finnie JW, Chidlow G, Blumbergs PC, Manavis J, Cai Z. 2009. Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields. Pathology 41:276–279.
   PubMed Web of Science ®Google Scholar
• Fragopoulou AF, Samara A, Antonelou MH, Xanthopoulou A, Papadopoulou A, Vougas K, Koutsogiannopoulou E, Anastasiadou E, Stravopodis DJ, Tsangaris GT, et al. 2012. Brain proteome response following whole body exposure of mice to mobile phone or wireless DECT base radiation. Electromagn Biol Med 31:250–274.
   PubMed Web of Science ®Google Scholar
• Frank-Raue K, Machens A, Leidig-Bruckner G, Rondot S, Haag C, Schulze E, Lorenz A, Kreissl MC, Dralle H, Raue F, et al. 2013. Prevalence and clinical spectrum of nonsecretory medullary thyroid carcinoma in a series of 839 patients with sporadic medullary thyroid carcinoma. Thyroid 23:294–300.
   PubMed Web of Science ®Google Scholar
• Franzellitti S, Valbonesi P, Contin A, Biondi C, Fabbri E. 2008. HSP70 expression in human trophoblast cells exposed to different 1.8 Ghz mobile phone signals. Radiat Res 170:488–497.
   PubMed Web of Science ®Google Scholar
• Freeman J, Carroll C, Asa S, Ezzat S. 2002. Genetic events in the evolution of thyroid cancer. J Otolaryngol 31:202–206.
   PubMedGoogle Scholar
• Frei P, Mohler E, Braun-Fahrlander C, Frohlich J, Neubauer G, Roosli M, Team Q. 2012. Cohort study on the effects of everyday life radio frequency electromagnetic field exposure on non-specific symptoms and tinnitus. Environ Int 38:29–36.
   PubMed Web of Science ®Google Scholar
• Group IS. 2010. Brain tumour risk in relation to mobile telephone use: Results of the INTERPHONE international case-control study. Int J Epidemiol 39:675–694.
   PubMed Web of Science ®Google Scholar
• Hamzany Y, Feinmesser R, Shpitzer T, Mizrachi A, Hilly O, Hod R, Bahar G, Otradnov I, Gavish M, Nagler RM. 2013. Is human saliva an indicator of the adverse health effects of using mobile phones? Antioxid Redox Signal 18:622–627.
   PubMed Web of Science ®Google Scholar
• Hardell L, Carlberg M, Soderqvist F, Mild KH. 2013. Pooled analysis of case-control studies on acoustic neuroma diagnosed 1997–2003 and 2007–2009 and use of mobile and cordless phones. Int J Oncol 43:1036–1044.
   PubMed Web of Science ®Google Scholar
• Hirose H, Suhara T, Kaji N, Sakuma N, Sekijima M, Nojima T, Miyakoshi J. 2008. Mobile phone base station radiation does not affect neoplastic transformation in BALB/3T3 cells. Bioelectromagnetics 29:55–64.
   PubMed Web of Science ®Google Scholar
• Hours M, Bernard M, Montestrucq L, Arslan M, Bergeret A, Deltour I, Cardis E. 2007. [Cell Phones and risk of brain and acoustic nerve tumours: The French INTERPHONE case-control study]. Rev Epidemiol Sante Publique 55:321–332.
   PubMed Web of Science ®Google Scholar
• Inskip PD, Hoover RN, Devesa SS. 2010. Brain cancer incidence trends in relation to cellular telephone use in the United States. Neuro Oncol 12:1147–1151.
   PubMed Web of Science ®Google Scholar
• Jin YB, Choi HD, Kim BC, Pack JK, Kim N, Lee YS. 2013. Effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on serum hormone levels in rats. J Radiat Res 54:430–437.
   PubMed Web of Science ®Google Scholar
• Kesari KK, Behari J, Kumar S. 2010. Mutagenic response of 2.45 GHz radiation exposure on rat brain. Int J Radiat Biol 86:334–343.
   PubMed Web of Science ®Google Scholar
• Kesari KK, Kumar S, Behari J. 2011. 900-MHz microwave radiation promotes oxidation in rat brain. Electromagn Biol Med 30:219–234.
   PubMed Web of Science ®Google Scholar
• Koyu A, Cesur G, Ozguner F, Akdogan M, Mollaoglu H, Ozen S. 2005. Effects of 900 MHz electromagnetic field on TSH and thyroid hormones in rats. Toxicol Lett 157:257–262.
   PubMed Web of Science ®Google Scholar
• Lee HJ, Pack JK, Kim TH, Kim N, Choi SY, Lee JS, Kim SH, Lee YS. 2010. The lack of histological changes of CDMA cellular phone-based radio frequency on rat testis. Bioelectromagnetics 31:528–534.
   PubMed Web of Science ®Google Scholar
• Lee S, Johnson D, Dunbar K, Dong H, Ge X, Kim YC, Wing C, Jayathilaka N, Emmanuel N, Zhou CQ, et al. 2005. 2.45 GHz radiofrequency fields alter gene expression in cultured human cells. FEBS Lett 579:4829–4836.
   PubMed Web of Science ®Google Scholar
• Little MP, Rajaraman P, Curtis RE, Devesa SS, Inskip PD, Check DP, Linet MS. 2012. Mobile phone use and glioma risk: Comparison of epidemiological study results with incidence trends in the United States. BMJ 344:e1147.
   PubMed Web of Science ®Google Scholar
• Marcello MA, Morari EC, Cunha LL, De Nadai Silva AC, Carraro DM, Carvalho AL, Soares FA, Vassallo J, Ward LS. 2013. P53 and expression of immunological markers may identify early stage thyroid tumors. Clin Dev Immunol 2013:846584. http://dx.doi.org/10.1155/2013/846584.
   PubMedGoogle Scholar
• Mashevich M, Folkman D, Kesar A, Barbul A, Korenstein R, Jerby E, Avivi L. 2003. Exposure of human peripheral blood lymphocytes to electromagnetic fields associated with cellular phones leads to chromosomal instability. Bioelectromagnetics 24:82–90.
   PubMed Web of Science ®Google Scholar
• Mazor R, Korenstein-Ilan A, Barbul A, Eshet Y, Shahadi A, Jerby E, Korenstein R. 2008. Increased levels of numerical chromosome aberrations after in vitro exposure of human peripheral blood lymphocytes to radiofrequency electromagnetic fields for 72 hours. Radiat Res 169:28–37.
   PubMed Web of Science ®Google Scholar
• Megha K, Deshmukh PS, Banerjee BD, Tripathi AK, Abegaonkar MP. 2012. Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats. Indian J Exp Biol 50:889–896.
   PubMed Web of Science ®Google Scholar
• Milham S, Morgan LL. 2008. A new electromagnetic exposure metric: High frequency voltage transients associated with increased cancer incidence in teachers in a California school. Am J Ind Med 51:579–586.
   PubMed Web of Science ®Google Scholar
• Misa Agustino MJ, Leiro JM, Jorge Mora MT, Rodriguez-Gonzalez JA, Jorge Barreiro FJ, Ares-Pena FJ, Lopez-Martin E. 2012. Electromagnetic fields at 2.45 GHz trigger changes in heat shock proteins 90 and 70 without altering apoptotic activity in rat thyroid gland. Biol Open 1:831–838.
   PubMed Web of Science ®Google Scholar
• Mortavazi S, Habib A, Ganj-Karami A, Samimi-Doost R, Pour-Abedi A, Babaie A. 2009. Alterations in TSH and thyroid hormones following mobile phone use. Oman Med J 24:274–278.
   PubMedGoogle Scholar
• Naziroglu M, Cig B, Dogan S, Uguz AC, Dilek S, Faouzi D. 2012. 2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca(2)(+) influx in human leukemia cancer cells. Int J Radiat Biol 88:449–456.
   PubMed Web of Science ®Google Scholar
• Oberto G, Rolfo K, Yu P, Carbonatto M, Peano S, Kuster N, Ebert S, Tofani S. 2007. Carcinogenicity study of 217 Hz pulsed 900 MHz electromagnetic fields in Pim1 transgenic mice. Radiat Res 168:316–326.
   PubMed Web of Science ®Google Scholar
• Poulsen AH, Friis S, Johansen C, Jensen A, Frei P, Kjaear SK, Dalton SO, Schuz J. 2013. Mobile phone use and the risk of skin cancer: A nationwide cohort study in Denmark. Am J Epidemiol 178:190–197.
   PubMed Web of Science ®Google Scholar
• Ruediger HW. 2009. Genotoxic effects of radiofrequency electromagnetic fields. Pathophysiology 16:89–102.
   PubMedGoogle Scholar
• Sadetzki S, Chetrit A, Jarus-Hakak A, Cardis E, Deutch Y, Duvdevani S, Zultan A, Novikov I, Freedman L, Wolf M. 2008. Cellular phone use and risk of benign and malignant parotid gland tumors – a nationwide case-control study. Am J Epidemiol 167:457–467.
   PubMed Web of Science ®Google Scholar
• Samimi H, Zaki Dizaji M, Ghadami M, Shahzadeh Fazeli A, Khashayar P, Soleimani M, Larijani B, Haghpanah V. 2013. Essential genes in thyroid cancers: Focus on fascin. J Diabetes Metab Disord 12:32. doi: 10.1186/2251-6581-12-32.
   PubMedGoogle Scholar
• Sanchez S, Milochau A, Ruffie G, Poulletier de Gannes F, Lagroye I, Haro E, Surleve-Bazeille JE, Billaudel B, Lassegues M, Veyret B. 2006. Human skin cell stress response to GSM-900 mobile phone signals. In vitro study on isolated primary cells and reconstructed epidermis. FEBS J 273:5491–5507.
   PubMed Web of Science ®Google Scholar
• Scholzen T, Gerdes J. 2000. The Ki-67 protein: From the known and the unknown. J Cell Physiol 182:311–322.
   PubMed Web of Science ®Google Scholar
• Schuz J, Bohler E, Berg G, Schlehofer B, Hettinger I, Schlaefer K, Wahrendorf J, Kunna-Grass K, Blettner M. 2006. Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany). Am J Epidemiol 163:512–520.
   PubMed Web of Science ®Google Scholar
• Sekijima M, Takeda H, Yasunaga K, Sakuma N, Hirose H, Nojima T, Miyakoshi J. 2010. 2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells. J Radiat Res 51:277–284.
   PubMed Web of Science ®Google Scholar
• Simon D, Daubos A, Pain C, Fitoussi R, Vie K, Taieb A, de Benetti L, Cario-Andre M. 2013. Exposure to acute electromagnetic radiation of mobile phone exposure range alters transiently skin homeostasis of a model of pigmented reconstructed epidermis. Int J Cosmet Sci 35:27–34.
   PubMed Web of Science ®Google Scholar
• Smith P, Kuster N, Ebert S, Chevalier HJ. 2007. GSM and DCS wireless communication signals: Combined chronic toxicity/carcinogenicity study in the Wistar rat. Radiat Res 168:480–492.
   PubMed Web of Science ®Google Scholar
• Sommer AM, Bitz AK, Streckert J, Hansen VW, Lerchl A. 2007. Lymphoma development in mice chronically exposed to UMTS-modulated radiofrequency electromagnetic fields. Radiat Res 168:72–80.
   PubMed Web of Science ®Google Scholar
• Swerdlow AJ, Feychting M, Green AC, Leeka Kheifets LK, Savitz DA. 2011. Mobile phones, brain tumors, and the interphone study: Where are we now? Environ Health Perspect 119:1534–1538.
   PubMed Web of Science ®Google Scholar
• Tillmann T, Ernst H, Ebert S, Kuster N, Behnke W, Rittinghausen S, Dasenbrock C. 2007. Carcinogenicity study of GSM and DCS wireless communication signals in B6C3F1 mice. Bioelectromagnetics 28:173–187.
   PubMed Web of Science ®Google Scholar
• Varsegi GM, Shidham V. 2009. Cell block preparation from cytology specimen with predominance of individually scattered cells. J Vis Exp 29. doi: 10.3791/1316.
   PubMedGoogle Scholar
• Vindeløv LL, Christensen IJ. 1990. A review of techniques and results obtained in one laboratory by an integrated system of methods designed for routine clinical flow cytometric DNA analysis. Cytometry 11:753–770.
   PubMedGoogle Scholar
• Wakeford R. 2004. The cancer epidemiology of radiation. Oncogene 23:6404–6428.
   PubMed Web of Science ®Google Scholar
• Waldmann P, Bohnenberger S, Greinert R, Hermann-Then B, Heselich A, Klug SJ, Koenig J, Kuhr K, Kuster N, Merker M, et al. 2013. Influence of GSM signals on human peripheral lymphocytes: Study of genotoxicity. Radiat Res 179:243–253.
   PubMed Web of Science ®Google Scholar
• Wartofsky L. 2010. Increasing world incidence of thyroid cancer: Increased detection or higher radiation exposure? Hormones (Athens) 9:103–108.
   PubMedGoogle Scholar
• Watilliaux A, Edeline JM, Leveque P, Jay TM, Mallat M. 2011. Effect of exposure to 1,800 MHz electromagnetic fields on heat shock proteins and glial cells in the brain of developing rats. Neurotox Res 20:109–119.
   PubMed Web of Science ®Google Scholar
• Whitehead TD, Brownstein BH, Parry JJ, Thompson D, Cha BA, Moros EG, Rogers BE, Roti Roti JL. 2005. Expression of the proto-oncogene Fos after exposure to radiofrequency radiation relevant to wireless communications. Radiat Res 164(4 Pt 1):420–430.
   PubMed Web of Science ®Google Scholar
• World Health Organization (WHO). 2011. IARC classifies radiofrequency elctromagnetic fields as possibly carcionogenic to humans. Press Release No. 208. Geneva: WHO.
   Google Scholar
• World Health Organization (WHO). June 2011. Electromagnetic fields and public health: mobile phones. Fact Sheet No. 193. Geneva: WHO.
   Google Scholar
• Yakymenko I, Sidorik E. 2010. Risks of carcinogenesis from electromagnetic radiation of mobile telephony devices. Exp Oncol 32:54–60.
   PubMedGoogle Scholar
• Yang L, Hao D, Wang M, Zeng Y, Wu S, Zeng Y. 2012. Cellular neoplastic transformation induced by 916 MHz microwave radiation. Cell Mol Neurobiol 32:1039–1046.
   PubMed Web of Science ®Google Scholar