Chitooligosaccharides decreases plasma lipid levels in healthy men

References

• Anderson JW, Deakins DA, Floore TL, Smith BM, Whitis SE. 1990. Dietary fiber and coronary heart diseases. Crit Rev Food Sci Nutr. 29:95–147.
   PubMed Web of Science ®Google Scholar
• Bokura H, Kobayashi S. 2003. Chitosan decreases total cholesterol in women: a randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr. 57:721–725.
   PubMed Web of Science ®Google Scholar
• Bucher HC, Griffith LE, Guyatt GH. 1998. Effect of HMG-CoA reductase inhibitors on stroke. A meta-analysis of randomized, controlled trials. Ann Intern Med. 128:89–95.
   PubMed Web of Science ®Google Scholar
• Chae SY, Jang MK, Nah JW. 2005. Influence of molecular weight on oral absorption of water soluble chitosans. J Control Release. 102:383–394.
   PubMed Web of Science ®Google Scholar
• Chiang MT, Yao HT, Chen HC. 2000. Effect of dietary chitosans with different viscosity on plasma lipids and lipid peroxidation in rats fed on a diet enriched with cholesterol. Biosci Biotechnol Biochem. 64:965–971.
   PubMed Web of Science ®Google Scholar
• Fukuda Y, Kimura K, Ayaki Y. 1991. Effect of chitosan feeding on intestinal bile acid metabolism in rats. Lipids. 26:395–399.
   PubMedGoogle Scholar
• Gallaher DD, Gallaher CM, Mahrt GJ, Carr TP, Hollingshead CH, Hesslink R, Wise J. 2002. A glucomannan and chitosan fiber supplement decreases plasma cholesterol and increases cholesterol excretion in overweight normocholesterolemic humans. J Am Coll Nutr. 21:428–433.
   PubMed Web of Science ®Google Scholar
• Geremias R, Pedrosa RC, Locatelli C, de Fávere VT, Coury-Pedrosa R, Laranjeira MCM. 2006. Lipid lowering activity of hydrosoluble chitosan and association with Aloe vera L. and Brassica olearaceae L. Phytother Res. 20:288–293.
   PubMedGoogle Scholar
• Han LK, Kimura Y, Okuda H. 1999. Reduction in fat storage during chitin-chitosan treatment in mice fed a high-fat diet. Int J Obes. 23:174–179.
   PubMed Web of Science ®Google Scholar
• Holme I. 1990. An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence. Circulation. 82:1916–1924.
   PubMed Web of Science ®Google Scholar
• Je JY, Park PJ, Kim SK. 2004. Free radical scavenging properties of hetero-chitooligosaccharides using an ESR spectroscopy. Food Chem Toxicol. 42:381–387.
   PubMed Web of Science ®Google Scholar
• Kanauchio O, Deguchi K, Imasato Y, Kobayashi E. 1994. Increasing effect of chitosan and ascorbic acid mixture on fecal dietary fat excretion. Biosci Biotechnol Biochem. 589:1617–1620.
   Google Scholar
• Lee JK, Kim SU, Kim JH. 1999. Modification of chitosan to improve its hypocholesterolemic capacity. Biosci Biotechnol Biochem. 63:833–839.
   PubMed Web of Science ®Google Scholar
• Liao FH, Shieh MJ, Chang NC, Chien YW. 2007. Chitosan supplementation lowers serum lipids and maintains normal calcium, magnesium, and iron status in hyperlipidemic patients. Nutr Res. 27:146–151.
   Web of Science ®Google Scholar
• Maezaki Y, Tsuji K, Nakagawa Y, Kawai Y, Akimoto M, Tsugita T, Takekawa W, Terada A, Hara H, Mitsuoka T. 1993. Hypocholesterolemic action of chitosans in adult males. Biosci Biotechnol Biochem. 57:1439–1444.
   PubMed Web of Science ®Google Scholar
• Manson JE, Tosteson H, Ridker PM, Satterfield S, Hebert P, O'Connor GT, Buring JE, Hennekens CH. 1992. The primary prevention of myocardial infarction. N Engl J Med. 326:1406–1416.
   PubMed Web of Science ®Google Scholar
• Martin MJ, Hulley SB, Browner WS, Kuller LH, Wentworth D. 1986. Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361,662 men. Lancet. 2:933–936.
   PubMed Web of Science ®Google Scholar
• Metso S, Ylitalo R, Nikkilä M, Wuolijoki E, Ylitalo P, Lehtimäki T. 2003. The effect of long-term microcrystalline chitosan therapy on plasma lipids and glucose concentrations in subjects with increased plasma total cholesterol: a randomized placebo-controlled double-blind crossover trial in healthy men and women. Eur J Clin Pharmacol. 59:741–746.
   PubMedGoogle Scholar
• Nauss JL, Thompson JL, Nagyvary J. 1983. The binding of micellar lipids to chitosan. Lipids. 18:714–719.
   PubMed Web of Science ®Google Scholar
• Park PJ, Je JY, Kim SK. 2003. Free radical scavenging activity of chitooligosaccharides by electron spin resonance spectrometry. J Agric Food Chem. 51:4624–4627.
   PubMed Web of Science ®Google Scholar
• Pittler MH, Abbot NC, Harkness EF, Ernst E. 1999. Randomized, double-blind trial of chitosan for body weight reduction. Eur J Clin Nutr. 53:379–381.
   PubMed Web of Science ®Google Scholar
• Sharrett AR, Ballantyne CM, Coady SA, Heiss G, Sorlie PD, Catellier D, Patsch W. 2001. Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoprotein A–I and B, and HDL density subfractions: the atherosclerosis risk in communities (aric) study. Circulation. 104:1108–1113.
   PubMed Web of Science ®Google Scholar
• Sugano M, Fujikawa T, Hiratsuji Y, Nakashima K, Fukuda N, Hasegawa Y. 1980. A novel use of chitosan as a hypocholesterolemic agent in rats. Am J Clin Nutr. 33:787–793.
   PubMed Web of Science ®Google Scholar
• Topping DL. 1991. Dietary fiber and cholesterol metabolism. Curr Opin Lipidol. 2:20–31.
   Google Scholar
• Wuolijoki E, Hirvela T, Ylitalo P. 1999. Decrease in serum LDL cholesterol with microcrystalline chitosan. Meth Find Exp Clin Pharmacol. 21:357–361.
   PubMed Web of Science ®Google Scholar
• Xu G, Huang X, Qin L, Wu J, Hu Y. 2007. Mechanism study of chitosan on lipid metabolism in hyperlipidemic rats. Asia Pac J Clin Nutr. 16:313–317.
   PubMedGoogle Scholar
• Yang Z, Harrison CM, Chuang GC, Ballinger SW. 2007. The role of tobacco smoke induced mitochondrial damage in vascular dysfunction and atherosclerosis. Mutat Res-Fund Mol M. 621:61–74.
   PubMedGoogle Scholar