Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice

References

• APA. (2000). Diagnostic and Statistical Manual of Mental Disorders. DSM-IV Edition. Washington, DC: American Psychiatric Association
   Google Scholar
• Axelson DA, Birmaher B. (2001). Relation between anxiety and depressive disorders in childhood and adolescence. Depress Anxiety 14:67–78
   PubMed Web of Science ®Google Scholar
• Backström T, Winberg S. (2013). Central corticotropin releasing factor and social stress. Front Neurosci 7:117 . doi: 10.3389/fnins.2013.00117
   PubMedGoogle Scholar
• Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, et al. (2006). Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311:864–8
   PubMed Web of Science ®Google Scholar
• Beuke CJ, Fischer R, McDowall J. (2003). Anxiety and depression: why and how to measure their separate effects. Clin Psychol Rev 23:831–48
   PubMed Web of Science ®Google Scholar
• Burke KC, Burke JD, Jr Regier DA, Rae DS. (1990). Age at onset of selected mental disorders in five community populations. Arch Gen Psychiatry 47:511–18
   PubMed Web of Science ®Google Scholar
• Buwalda B, Stubbendorff C, Zickert N, Koolhaas JM. (2013). Adolescent social stress does not necessarily lead to a compromised adaptive capacity during adulthood: a study on the consequences of social stress in rats. Neuroscience 249:258–70
   PubMed Web of Science ®Google Scholar
• Buwalda B, de Boer SF, Schmidt ED, Felszeghy K, Nyakas C, Sgoifo A, Van der Vegt BJ, et al. (1999). Long-lasting deficient dexamethasone suppression of hypothalamic-pituitary-adrenocortical activation following peripheral CRF challenge in socially defeated rats. J Neuroendocrinol 11:513–20
   PubMedGoogle Scholar
• Charney DS, Manji HK. (2004). Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention. Sci STKE 225:re5 . doi: 10.1126/stke.2252004re5
   Google Scholar
• Das-Munshi J, Goldberg D, Bebbington PE, Bhugra DK, Brugha TS, Dewey ME, Jenkins R, et al. (2008). Public health significance of mixed anxiety and depression: beyond current classification. Br J Psychiatry 192:171–7
   PubMed Web of Science ®Google Scholar
• Doremus-Fitzwater TL, Varlinskaya EI, Spear LP. (2010). Motivational systems in adolescence: possible implications for age differences in substance abuse and other risk-taking behaviors. Brain Cogn 72:114–23
   PubMed Web of Science ®Google Scholar
• Eiland L, Romeo RD. (2013). Stress and the developing adolescent brain. Neuroscience 249:162–71
   PubMed Web of Science ®Google Scholar
• Eisch AJ, Bolaños CA, de Wit J, Simonak RD, Pudiak CM, Barrot M, Verhaagen J, Nestler EJ. (2003). Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biol Psychiatry 54:994–1005
   PubMed Web of Science ®Google Scholar
• Findling RL, McNamara NK, Stansbrey RJ, Feeny NC, Young CM, Peric FV, Youngstrom EA. (2006). The relevance of pharmacokinetic studies in designing efficacy trials in juvenile major depression. J Child Adolesc Psychopharmacol 16:131–45
   PubMed Web of Science ®Google Scholar
• Gladstone GL, Parker GB, Malhi GS. (2006). Do bullied children become anxious and depressed adults?: a cross-sectional investigation of the correlates of bullying and anxious depression. J Nerv Ment Dis 194:201–8
   PubMed Web of Science ®Google Scholar
• Golden SA, Covington HE, 3rd Berton O, Russo SJ. (2011). A standardized protocol for repeated social defeat stress in mice. Nat Protoc 6:1183–91
   PubMed Web of Science ®Google Scholar
• Hankin BL, Abramson LY, Moffitt TE, Silva PA, McGee R, Angell KE. (1998). Development of depression from preadolescence to young adulthood: emerging gender differences in a 10-year longitudinal study. J Abnorm Psychol 107:128–40
   PubMed Web of Science ®Google Scholar
• Heinrichs SC, Koob GF. (2006). Application of experimental stressors in laboratory rodents. Curr Protoc Neurosci Chapter 8:Unit8.4
   PubMedGoogle Scholar
• Huang GB, Zhao T, Muna SS, Bagalkot TR, Jin HM, Chae HJ, Chung YC. (2013). Effects of chronic social defeat stress on behaviour, endoplasmic reticulum proteins and choline acetyltransferase in adolescent mice. Int J Neuropsychopharmacol 16:1635–47
   PubMedGoogle Scholar
• Iñiguez SD, Warren BL, Bolaños-Guzmán CA. (2010a). Short- and long-term functional consequences of fluoxetine exposure during adolescence in male rats. Biol Psychiatry 67:1057–66
   PubMed Web of Science ®Google Scholar
• Iñiguez SD, Warren BL, Parise EM, Alcantara LF, Schuh B, Maffeo ML, Manojlovic Z, Bolaños-Guzmán CA. (2009). Nicotine exposure during adolescence induces a depression-like state in adulthood. Neuropsychopharmacology 34:1609–24
   PubMed Web of Science ®Google Scholar
• Iñiguez SD, Vialou V, Warren BL, Cao JL, Alcantara LF, Davis LC, Manojlovic Z, et al. (2010b). Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress. J Neurosci 30:7652–63
   PubMedGoogle Scholar
• Iñiguez SD, Alcantara LF, Warren BL, Riggs LM, Parise EM, Vialou V, Wright KN, et al. (2014). Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood. J Neurosci 34:1007–21
   PubMedGoogle Scholar
• Jiang C, Salton SR. (2013). The role of neurotrophins in major depressive disorder. Transl Neurosci 4:46–58
   PubMed Web of Science ®Google Scholar
• Kessler RC, Avenevoli S, Ries Merikangas K. (2001). Mood disorders in children and adolescents: an epidemiologic perspective. Biol Psychiatry 49:1002–14
   PubMed Web of Science ®Google Scholar
• Krishnan V, Nestler EJ. (2008). The molecular neurobiology of depression. Nature 455:894–902
   PubMed Web of Science ®Google Scholar
• Krishnan V, Nestler EJ. (2011). Animal models of depression: molecular perspectives. Curr Top Behav Neurosci 7:121–47
   PubMedGoogle Scholar
• Krishnan V, Han MH, Mazei-Robison M, Iñiguez SD, Ables JL, Vialou V, Berton O, et al. (2008). AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biol Psychiatry 64:691–700
   PubMed Web of Science ®Google Scholar
• Krishnan V, Han MH, Graham DL, Berton O, Renthal W, Russo SJ, Laplant Q, et al. (2007). Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 131:391–404
   PubMed Web of Science ®Google Scholar
• Kudryavtseva NN, Bakshtanovskaya IV, Koryakina LA. (1991). Social model of depression in mice of C57BL/6J strain. Pharmacol Biochem Behav 38:315–20
   PubMed Web of Science ®Google Scholar
• Kupfer DJ, Frank E, Phillips ML. (2012). Major depressive disorder: new clinical, neurobiological, and treatment perspectives. Lancet 379:1045–55
   PubMed Web of Science ®Google Scholar
• Laviola G, Macri S, Adriani W, Morley Fletcher S. (2002). Psychobiological determinants of risk behavior in adolescence. Ann Ist Super Sanita 38:279–87
   PubMedGoogle Scholar
• Lewinsohn PM, Hops H, Roberts RE, Seeley JR, Andrews JA. (1993). Adolescent psychophathology: I. Prevalence and incidence of depression and other DSM-III-R disorders in high school students. J Abnorm Psychol 102:133–44
   PubMed Web of Science ®Google Scholar
• Malkesman O, Weller A. (2009). Two different putative genetic animal models of childhood depression – a review. Prog Neurobiol 88:153–69
   PubMed Web of Science ®Google Scholar
• McCormick CM, Mathews IZ, Thomas C, Waters P. (2010). Investigations of HPA function and the enduring consequences of stressors in adolescence in animal models. Brain Cogn 72:73–85
   PubMed Web of Science ®Google Scholar
• Miczek KA. (1979). A new test for aggression in rats without aversive stimulation: differential effects of d-amphetamine and cocaine. Psychopharmacology (Berl) 60:253–9
   PubMed Web of Science ®Google Scholar
• Montgomery KC. (1955). The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol 48:254–60
   PubMed Web of Science ®Google Scholar
• Niwa M, Jaaro-Peled H, Tankou S, Seshadri S, Hikida T, Matsumoto Y, Cascella NG, et al. (2013). Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science 339:335–9
   PubMed Web of Science ®Google Scholar
• Papp M, Willner P, Muscat R. (1991). An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress. Psychopharmacology (Berl) 104:255–9
   PubMed Web of Science ®Google Scholar
• Parmigiani S, Palanza P, Rogers J, Ferrari PF. (1999). Selection, evolution of behavior and animal models in behavioral neuroscience. Neurosci Biobehav Rev 23:957–69
   PubMed Web of Science ®Google Scholar
• Paus T, Keshavan M, Giedd JN. (2008). Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 9:947–57
   PubMed Web of Science ®Google Scholar
• Pellow S, Chopin P, File SE, Briley M. (1985). Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14:149–67
   PubMed Web of Science ®Google Scholar
• Porsolt RD, Le Pichon M, Jalfre M. (1977). Depression: a new animal model sensitive to antidepressant treatments. Nature 266:730–2
   PubMed Web of Science ®Google Scholar
• Richards JM, Plate RC, Ernst M. (2012). Neural systems underlying motivated behavior in adolescence: implications for preventative medicine. Prev Med 55:s7–16
   Google Scholar
• Spear LP. (2000). The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24:417–63
   PubMed Web of Science ®Google Scholar
• Stone EA, Quartermain D. (1997). Greater behavioral effects of stress in immature as compared to mature male mice. Physiol Behav 63:143–5
   PubMedGoogle Scholar
• Tirelli E, Laviola G, Adriani W. (2003). Ontogenesis of behavioral sensitization and conditioned place preference induced by psychostimulants in laboratory rodents. Neurosci Biobehav Rev 27:163–78
   PubMed Web of Science ®Google Scholar
• Trainor BC, Pride MC, Villalon Landeros R, Knoblauch NW, Takahashi EY, Silva AL, Crean KK. (2011). Sex differences in social interaction behavior following social defeat stress in the monogamous California mouse (Peromyscus californicus). PLoS One 6:e17405
   Google Scholar
• Tsoory M, Cohen H, Richter-Levin G. (2007). Juvenile stress induces a predisposition to either anxiety or depressive-like symptoms following stress in adulthood. Eur Neuropsychopharmacol 17:245–56
   PubMed Web of Science ®Google Scholar
• Ver Hoeve ES, Kelly G, Luz S, Ghanshani S, Bhatnagar S. (2013). Short-term and long-term effects of repeated social defeat during adolescence or adulthood in female rats. Neuroscience 249:63–73
   PubMedGoogle Scholar
• Wals M, Verhulst F. (2005). Child and adolescent antecedents of adult mood disorders. Curr Opin Psychiatry 18:15–19
   PubMed Web of Science ®Google Scholar
• Warren BL, Iñiguez SD, Alcantara LF, Wright KN, Parise EM, Weakley SK, Bolaños-Guzmán CA. (2011). Juvenile administration of concomitant methylphenidate and fluoxetine alters behavioral reactivity to reward- and mood-related stimuli and disrupts ventral tegmental area gene expression in adulthood. J Neurosci 31:10347–58
   PubMedGoogle Scholar
• Warren BL, Vialou VF, Iñiguez SD, Alcantara LF, Wright KN, Feng J, Kennedy PJ, et al. (2013). Neurobiological sequelae of witnessing stressful events in adult mice. Biol Psychiatry 73:7–14
   PubMed Web of Science ®Google Scholar
• Watt MJ, Burke AR, Renner KJ, Forster GL. (2009). Adolescent male rats exposed to social defeat exhibit altered anxiety behavior and limbic monoamines as adults. Behav Neurosci 123:564–76
   PubMed Web of Science ®Google Scholar
• Willner P, Towell A, Sampson D, Sophokleous S, Muscat R. (1987). Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology (Berl) 93:358–64
   PubMed Web of Science ®Google Scholar
• Zito JM, Tobi H, de Jong-van den Berg LT, Fegert JM, Safer DJ, Janhsen K, Hansen DG, et al. (2006). Antidepressant prevalence for youths: a multi-national comparison. Pharmacoepidemiol Drug Saf 15:793–8
   PubMedGoogle Scholar