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Stress
The International Journal on the Biology of Stress
Volume 17, 2014 - Issue 4
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Research Article

Prevention of cardiac events caused by surgical stress in aged rats: simultaneously activating β2-adrenoceptor and inhibiting β1-adrenoceptor

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Pages 373-381 | Received 19 Jan 2014, Accepted 08 Apr 2014, Published online: 08 May 2014

References

  • Ahmed A. (2003). Myocardial beta-1 adrenoceptor down-regulation in aging and heart failure: implications for beta-blocker use in older adults with heart failure. Eur J Heart Fail 5:709–15
  • Ahmet I, Krawczyk M, Heller P, Moon C, Lakatta EG, Talan MI. (2004). Beneficial effects of chronic pharmacological manipulation of beta-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy. Circulation 110:1083–90
  • Ahmet I, Krawczyk M, Zhu W, Woo AY, Morrell C, Poosala S, Xiao RP, et al. (2008). Beta(2)-adrenoceptor agonist clenbuterol reduces infarct size and myocardial apoptosis after myocardial ischaemia/reperfusion in anaesthetized rats. J Pharmacol Exp Ther 325:491–9
  • Ahmet I, Lakatta EG, Talan MI. (2005). Pharmacological stimulation of beta2-adrenergic receptors (beta2AR) enhances therapeutic effectiveness of beta1AR blockade in rodent dilated ischemic cardiomyopathy. Heart Fail Rev 10:289–96
  • Billman GE, Kukielka M, Kelley R, Moustafa-Bayoumi M, Altschuld RA. (2006). Endurance exercise training attenuates cardiac beta2-adrenoceptor responsiveness and prevents ventricular fibrillation in animals susceptible to sudden death. Am J Physiol Heart Circ Physiol 290:H2590–9
  • Bristow MR, Ginsburg R, Umans V, Fowler M, Minobe W, Rasmussen R, Zera P, et al. (1986). Beta 1- and beta2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta1-receptor down-regulation in heart failure. Circ Res 59:297–309
  • Brodde OE. (2007). Beta-adrenoceptor blocker treatment and the cardiac beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in chronic heart failure. Naunyn Schmiedebergs Arch Pharmacol 374:361–72
  • Brodde OE. (2008). Beta-1 and beta-2 adrenoceptor polymorphisms: functional importance, impact on cardiovascular diseases and drug responses. Pharmacol Ther 117:1–129
  • Christ T, Galindo-Tovar A, Thoms M, Ravens U, Kaumann AJ. (2009). Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart. Br J Pharmacol 156:62–83
  • Deneer VH, van Hemel NM. (2011). Antiarrhythmic treatment in the elderly different? A review of the specific changes. Drugs Aging 28:617–33
  • Engebretsen KM, Kaczmarek KM, Morgan J, Holger JS. (2011). High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning. Clin Toxicol (Phila) 49:277–83
  • Hao Y, Sun Y, Xu C, Jiang X, Sun H, Wu Q, Yan C, Gu S. (2009). Improvement of contractile function in isolated cardiomyocytes from ischemia-reperfusion rats by ginkgolide B pretreatment. J Cardiovasc Pharmacol 54:3–9
  • Hossain M, Rashid M, Bhuiyan MA, Nakamura T, Ozaki M, Nagatomo T. (2009). Mutagenesis of important amino acid reveals unconventional homologous internalization of beta(1)-adrenergic receptor. Life Sci 85:339–44
  • Kaye D, Esler M. (2005). Sympathetic neuronal regulation of the heart in aging and heart failure. Cardiovasc Res 66:256–64
  • Kaye DM, Esler MD. (2008). Autonomic control of the aging heart. Neuromolecular Med 10:179–86
  • Li J, Yan B, Huo Z, Liu Y, Xu J, Sun Y, Liu Y, et al. (2010). β2- but not β1-adrenoceptor activation modulates intracellular oxygen availability. J Physiol 588:2987–98
  • Maruyama Y. (2012). Aging and arterial-cardiac interactions in the elderly. Int J Cardiol 155:14–19
  • Metzler B, Mair J, Lercher A, Schaber C, Hintringer F, Pachinger O, Xu Q. (2001). Mouse model of myocardial remodelling after ischemia: role of intercellular adhesion molecule-1. Cardiovasc Res 49:399–407
  • Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, et al. (2010). β2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science 327(5973):1653–7
  • Poldermans D, Hoeks SE, Feringa HH. (2008). Preoperative risk assessment and risk reduction before surgery. J Am Coll Cardiol 51:1913–24
  • Rehsia NS, Dhalla NS. (2010). Mechanisms of the beneficial effects of beta-adrenoceptor antagonists in congestive heart failure. Exp Clin Cardiol 15:e86–95
  • Rybin VO, Xu X, Lisanti MP, Steinberg SF. (2000). Differential targeting of β-adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae: amechanism to functionally regulate the cAMP signaling pathway. J Biol Chem 275:41447–57
  • Stoschitzky K. (2001). Beta-blockers and non-cardiac surgery. J Clin Basic Cardiol 4:21–3
  • Sun H, Zhou F, Wang Y, Zhang Y, Chang A, Chen Q. (2006). Effects of beta-adrenoceptors overexpression on cell survival are mediated by Bax/Bcl-2 pathway in rat cardiac myocytes. Pharmacology 78:98–104
  • Suttner S, Boldt J, Mengistu A, Lang K, Mayer J. (2009). Influence of continuous perioperative beta-blockade in combination with phosphodiesterase inhibition on haemodynamics and myocardial ischaemia in high-risk vascular surgery patients. Br J Anaesth 102:597–607
  • VanDenKerkhof EG, Milne B, Parlow JL. (2003). Knowledge and practice regarding prophylactic perioperative beta blockade in patients undergoing noncardiac surgery: a survey of Canadian anesthesiologists. Anesth Analg 96:1558–65
  • Wijeysundera DN, Beattie WS, Karkouti K, Neuman MD, Austin PC, Laupacis A. (2011). Association of echocardiography before major elective non-cardiac surgery with postoperative survival and length of hospital stay: population based cohort study. Brit Med J 342:d3695
  • Wu Q, Zhao Z, Sun H, Hao YL, Yan CD, Gu SL. (2008). Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia-reperfusion. Exp Physiol 93:1034–43
  • Xiao RP, Zhang SJ, Chakir K, Avdonin P, Zhu W, Bond RA, Balke CW, et al. (2003). Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR) – but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts. Circulation 108:1633–9
  • Xu C, Liu A, Sun H, Wang G, Gao L, Hao Y, Yan C. (2010). beta2- Adrenoceptor confers cardioprotection against hypoxia in isolated ventricular myocytes and the effects depend on estrogenic environment. J Recept Signal Transduct Res 30:255–61
  • Zaugg M, Schaub MC, Pasch T, Spahn DR. (2002). Modulation of beta-adrenergic receptor subtype activities in perioperative medicine: mechanisms and sites of action. Br J Anaesth 88:101–23 (Review)
  • Zhang Q, Xiang J, Wang X, Liu H, Hu B, Feng M, Fu Q. (2010). Beta(2)-adrenoceptor agonist clenbuterol reduces infarct size and myocardial apoptosis after myocardial ischaemia/reperfusion in anaesthetized rats. Br J Pharmacol 160:1561–72

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