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Review Article

Mode-of-action and human relevance framework analysis for rat Leydig cell tumors associated with sulfoxaflor

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Pages 25-44 | Received 04 Oct 2013, Accepted 29 Mar 2014, Published online: 16 May 2014

References

  • Ben-Jonathan N, Hnasko R. (2001). Dopamine as a prolactin (PRL) inhibitor. Endocr Rev, 22, 724–63.
  • Boobis AR, Cohen SM, Dellarco V, McGregor D, Meek ME, Vickers C, et al. (2006). IPCS framework for analyzing the relevance of a cancer mode of action for humans. Crit Rev Toxicol, 36, 781–92.
  • Boobis AR, Cohen SM, Dellarco V, McGregor D, Meek ME, Vickers C, et al. (2007). IPCS Framework for analysing the relevance of a cancer mode of action for humans. Harmonization Project Document No. 4, World Health Organization, Geneva. pp. 10–29.
  • Boobis AR, Cohen SM, Dellarco V, McGregor D, Meek ME, Vickers C, et al. (2006). IPCS framework for analyzing the relevance of a cancer mode of action for humans. Crit Rev Toxicol, 36, 781–92.
  • Boobis AR, Doe JE, Heinrich-Hirsch B, Meek ME, Munn S, Ruchirawat M, et al. (2008). IPCS framework for analyzing the relevance of a noncancer mode of action for humans. Crit Rev Toxicol, 38, 87–96.
  • Blaha CD, Winn P. (1993). Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmented nucleus-lesioned rats. J Neurosci, 13, 1035–44.
  • Boorman GA, Chapin RE, Mitsumori K. (1990). Testis and Epididymis. In: Boorman GA, Eustis SL, Elwell MR, Montgomery CA, MacKenzie WF, Eds. Pathology of the Fischer Rat: Reference and Atlas. San Diego: Academic Press, pp. 405–18.
  • Boorman GA, Hamlin MH, Eustis SL. (1987). Focal interstitial cell hyperplasia testes, rat. In: Jones TC, Mohr U, Hunt RD, Eds. Genital System, Monographs on Pathology of Laboratory Animals Sponsored by the International Life Sciences Institute. Berlin, Heidelberg: Springer Verlag, pp. 201–204.
  • Casarett LJ, Doull J, Klaassen CD. (2007). Casarett & Doull's Toxicology: The Basic Science of Poisons. New York: McGraw-Hill Professional.
  • Cassels BK, Bermúdez I, Dajas F, Abin-Carriquiry JA, Wonnacott S. (2005). From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research. Drug Discov Today, 10, 1657–65.
  • Clayton RN, Huhtaniemi IT. (1982). Absence of gonadotropin-releasing hormone receptors in human gonadal tissue. Nature, 299, 56–9.
  • Clegg ED, Cook JC, Chapin RE, Foster PMD, Daston GP. (1997). Leydig cell hyperplasia and adenoma formation: mechanisms and relevance to humans. Reprod Toxicol, 11, 101–121.
  • Cohen SM, Meek ME, Klaunig JE, Patton DE, Fenner-Crisp PA. (2003). The human relevance of information on carcinogenic modes of action: Overview. Crit Rev Toxicol, 33, 581–9.
  • Cook JC, Klinefelter GR, Hardisty JF, Sharpe RM, Foster PM. (1999). Rodent Leydig cell tumorigenesis: a review of the physiology, pathology, mechanisms, and relevance to humans. Crit Rev Toxicol, 29, 169–261.
  • Coulson M, Gibson GG, Plant N, Hammond T, Graham M. (2003). Lansoprazole increases testosterone metabolism and clearance in male Sprague-Dawley rats: implications for Leydig cell carcinogenesis. Toxicol Appl Pharmacol, 192, 154–63.
  • Donaubauer HH, Kramer M, Kreig K, Mayer D, Von Rechenberg W, Sandow J, Schutz E. (1987). Investigations of the carcinogenicity of the LH-RH analogue buserelin (HOE 766) in rats using the subcutaneous route of administration. Fund Appl Toxicol, 9, 738–52.
  • ECHA. (2013). Risk Assessment Committee Conclusion (http://www.echa.europa.eu/view-article/-/journal_content/title/rac-concludes-on-nine-scientific-opinions-for-clh). Accessed on March 23, 2014.
  • Ellis-Hutchings RG, Rasoulpour RJ, Terry C, Carney EW, Billington R. (2014). Human relevance framework evaluation of a novel rat developmental toxicity mode of action induced by sulfoxaflor. Crit Rev Toxicol, 44, 45–62.
  • Feldman BJ, Feldman D. (2001). The development of androgen-independent prostate cancer. Nat Rev Cancer, 1, 34–45.
  • Gianoulakis C. (1998). Alcohol-seeking behavior: the roles of the hypothalamic-pituitary-adrenal axis and the endogenous opioid system. Alcohol Health Res World, 22, 202–10.
  • Hammond GL. (2011). Diverse roles for sex hormone-binding globulin in reproduction. Biol Reprod, 85, 431–41.
  • Huhtaniemi IT. (1983). Gonadotrophin receptors: correlates with normal and pathological functions of the human ovary and testis.In: Clinical Endocrinology and Metabolism: Receptors in Health and Disease. Philadelphia : Clayton WB Saunders. pp. 117–132.
  • JMPR (Joint FAO/WHO Meeting on Pesticide Residues). (2011). Sulfoxaflor Monograph. Geneva, 20–29 September 2011.
  • Katzung BG. (1995). Introduction. In: Katzung BG, Eds. Basic and Clinical Pharmacology. Appleton and Lang: Connecticut. pp. 117–132.
  • Kerr JB, Sharpe RM. (1986). Effects and interactions of LH and LHRH agonist on testicular morphology and function in hypophysectomized rats. J Reprod Fertil, 76, 175–92.
  • Korenbrot CC, Huhtaniemi IT, Weiner RI. (1977). Preputial separation as an external sign of pubertal development in the male rat. Biol Reprod, 17, 298–303.
  • Kondarewicz A, Kolasa A, Zawiślak B, Baranowska-Bosiacka I, Marchlewicz M, et al. (2011). Testis morphology in rats chronically treated with letrozole, an aromatase inhibitor. Folia Histochem Cytobiol, 49, 677–84.
  • LeBaron MJ, Bhaskar Gollapudi B, Terry C, Billington R, Rasoulpour RJ. (2014). Human relevance framework for rodent liver tumors induced by the insecticide sulfoxaflor. Crit Rev Toxicol, 44, 15–24.
  • Leslie GB, Noakes DN, Pollitt FD, Roe FJ, Walker TF. (1981). A two-year study with cimetidine in the rat: assessment for chronic toxicity and carcinogenicity. Toxicol Appl Pharm, 61, 119–37.
  • Marty MS, Crissman JW, Carney EW. (2001). Evaluation of the male pubertal assay's ability to detect thyroid inhibitors and dopaminergic agents. Toxicol Sci, 60, 63–76.
  • Maskos U. (2010). Role of endogenous acetylcholine in the control of the dopaminergic system via nicotinic receptors. J Neurochem, 114, 641–646. doi:10.1111/J.1471-4159.2010.06798.x (epub).
  • Mati W, Lam G, Dahl C, Anderson T, Balslev E (2002). Leydig cell tumour – a rare testicular tumour. Int Urol Nephrol, 33, 103–6.
  • Meek ME, Bucher JR, Cohen SM, Dellarco V, Hill RN, Lehman-McKeeman LD, et al. (2003). A framework for human relevance analysis of information on carcinogenic modes of action. Crit Rev Toxicol, 33, 591–653.
  • Negro-Vilar A, Valenca MM. (1988). Male neuroendocrinology and endocrine evaluation. In: Lamb JC IV, Foster PMD, Eds. Physiology and Toxicology of Male Reproduction. London: Academic Press Inc, pp. 124–7.
  • Newbold RR, Bullock BC, McLachlan JA. (1987). Testicular tumors in mice exposed in utero to diethylstilbestrol. J Urol, 138, 1446–50.
  • Prahalada S, Majka JA, Soper KA, Nett TM, Bagdon WJ, Peter CP, et al. (1994). Leydig cell hyperplasia and adenomas in mice treated with finasteride, a 5-alpha reductase inhibitor: a possible mechanism. Fund Appl Toxicol, 22, 211–19.
  • Prentice DE, Miekle AW. (1995). A review of drug-induced leydig cell hyperplasia and neoplasia in the rat and some comparisons with man. Hum Exp Toxicol, 14, 562–72.
  • Prentice DE, Siegel RA, Donatsch P, Qureshi S, Ettlin RA. (1992). Mesulergine induced Leydig cell tumours, a syndrome involving the pituitary-testicular axis of the rat. Arch. Toxicol, 15, 197–204.
  • Rouquie D, Friry-Santini C, Schorsch F, Tinwell H, Bars R. (2009). Standard and molecular NOAELs for rat testicular toxicity induced by flutamide. Toxicol Sci, 109, 59–65.
  • Seed J, Carney EW, Corley RA, Crofton KM, DeSesso JM, Foster PM, et al. 2005. Overview: Using mode of action and life stage information to evaluate the human relevance of animal toxicity data. Crit Rev Toxicol, 35, 664–72.
  • Sonich-Mullin C, Fielder R, Wiltse J, Baetcke K, Dempsey J, Fenner-Crisp P, et al. (2001). IPCS Conceptual framework for evaluating a mode of action for chemical carcinogenesis. Regul Toxicol Pharmacol, 34, 146–52.
  • Steers WD. (2001). 5alpha-reductase activity in the prostate. Urololgy, 58, 17–24.
  • Terry C, Rasoulpour RJ, Saghir S, Marty S, Bhaskar Gollapudi B, Billington R. (2014). Application of a novel integrated toxicity testing strategy incorporating “3R” principles of animal research to evaluate the safety of a new agrochemical, sulfoxaflor. Crit Rev Toxicol, 44, 1–14.
  • Turner KJ, Morley M, Atanassova N, Swanston ID, Sharpe RM. (2000). Effect of chronic administration of an aromatase inhibitor to adult male rats on pituitary and testicular function and fertility. J Endocrinol, 164, 225–38.
  • US EPA. (2005). Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001B.
  • US EPA. (2012). Human Health Risk Review and Carcinogenicity Assessment Review Committee (CARC) Memo (published for public commenting January 2013, DR D2-382604).
  • Waalkes MP, Anver M, Diwan BA. (1999). Carcinogenic effects of cadmium in the noble (NBL/Cr) rat: induction of pituitary, testicular, and injection site tumors and intraepithelial proliferative lesions of the dorsolateral prostate. Toxicol Sci, 52, 154–61.
  • Williams VL, DeGuzman A, Dang H, Kawaminami M, Ho TW, Carter DG, Walker AM. (2007). Common and specific effects of the two major forms of prolactin in the rat testis. Am J Physiol Endocrinol Metab, 293, E1795–E803.
  • Wilson VS, Bobseine K, Lambright CR, Gray LE Jr. (2002). A novel cell line, MDA-kb2, that stably expresses an androgen and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists. Toxicol Sci, 66, 69–81.
  • Wilson VS, Bobseine K, Gray LE Jr. (2004). Development and Characterization of a cell line that stably expresses an estrogen-responsive luciferase reporter for the detection of estrogen receptor agonist and antagonists. Toxicol Sci, 81, 69–77.
  • Wolf CJ, LeBlanc GA, Ostby JS, Gray LE Jr. (2000). Characterization of the period of sensitivity of fetal male sexual development to vinclozolin. Toxicol Sci, 55, 152–61.

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