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Letter to the Editor

Aggressive congenital juvenile myelomonocytic leukemia associated with somatic KRAS p.G13D mutation and concurrent germline IGF1R duplication

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Pages 1175-1178 | Received 22 May 2014, Accepted 04 Aug 2014, Published online: 29 Sep 2014

References

  • Flotho C, Kratz CP, Niemeyer CM. How a rare pediatric neoplasia can give important insights into biological concepts: a perspective on juvenile myelomonocytic leukemia. Haematologica 2007;92: 1441–1446.
  • Loh ML. Childhood myelodysplastic syndrome: focus on the approach to diagnosis and treatment of juvenile myelomonocytic leukemia. Hematology Am Soc Hematol Educ Program 2010:357–362.
  • Niemeyer CM, Arico M, Basso G, et al. Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS). Blood 1997;89:3534–3543.
  • Chan RJ, Cooper T, Kratz CP, et al. Juvenile myelomonocytic leukemia: a report from the 2nd International JMML Symposium. Leuk Res 2009;33:355–362.
  • MacDonald JR, Ziman R, Yuen RK, et al. The Database of Genomic Variants: a curated collection of structural variation in the human genome. Nucleic Acids Res 2014;42:D986–D992.
  • Cottrell CE, Al-Kateb H, Bredemeyer AJ, et al. Validation of a next-generation sequencing assay for clinical molecular oncology. J Mol Diagn 2014;16:89–105.
  • Niemeyer CM, Kang MW, Shin DH, et al. Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. Nat Genet 2010;42:794–800.
  • Matsuda K, Shimada A, Yoshida N, et al. Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. Blood 2007;109:5477–5480.
  • Roberts AE, Allanson JE, Tartaglia M, et al. Noonan syndrome. Lancet 2013;381:333–342.
  • Bader JL, Miller RW. Neurofibromatosis and childhood leukemia. J Pediatr 1978;92:925–929.
  • Sakaguchi H, Okuno Y, Muramatsu H, et al. Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia. Nat Genet 2013;45:937–941.
  • Takagi M, Shinoda K, Piao J, et al. Autoimmune lymphoproliferative syndrome-like disease with somatic KRAS mutation. Blood 2011;117:2887–2890.
  • Grothey A, Voigt W, Schober C, et al. The role of insulin-like growth factor I and its receptor in cell growth, transformation, apoptosis, and chemoresistance in solid tumors. J Cancer Res Clin Oncol 1999;125:166–173.
  • Kim JS, Kim ES, Liu D, et al. Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer. Cancer 2012;118:2454–2465.
  • He Q, Li X, Zhang Z, et al. Overexpression of IGF-IR in malignant clonal cells in bone marrow of myelodysplastic syndromes. Cancer Invest 2010;28:983–988.

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