L-Asparaginase and PEG Asparaginase— Past, Present, and Future

References

• Kidd J. G. Regression of transplanted lymphomas induced in vivo by means of normal guinea pig serum. J. Exp. Med. 1953; 98: 565
   PubMed Web of Science ®Google Scholar
• Broome J. D. Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. J. Exp. Med. 1963; 118: 99
   PubMed Web of Science ®Google Scholar
• Hill J. M., Roberts J., Loeb E., Khan A., MacLellan A., Hill R. B. L-asparaginase therapy for leukemia. JAMA 1967; 202: 882
   PubMed Web of Science ®Google Scholar
• Hill J. M., Loeb E., MacLellan A., Khan A., Roberts J., Shields W. F., Hill N. O. Response to highly purified L-asparaginase during therapy of acute leukemia. Cancer Res. 1969; 29: 1574
   PubMed Web of Science ®Google Scholar
• Capizzi R. L., Bertino J. R., Skeel R. T., Creasey W. A., Zanes R., Olayon C., Peterson R. G., Hand-schumacher R. E. L-asparaginase: clinical, biochemical, pharmacological and immunological studies. Ann. Intern. Med. 1971; 74: 893
   PubMed Web of Science ®Google Scholar
• Evans W. E., Tsiatis A., Rivera G., Murphy S. B., Dahl G. R., Denison M., Crom W. R., Barker L. F., Mauer A. M. Anaphylactoid reactions to Esch-erichia coli and Erwinia asparaginase in children with leukemia and lymphoma. Cancer 1982; 49: 1378
   PubMed Web of Science ®Google Scholar
• Park Y. K., Abuchowski A., Davis S., Davis F. Pharmacology of Escherichia coli-L-asparaginase polyethylene glycol adduct. Anticancer Res. 1981; 1: 373
   PubMed Web of Science ®Google Scholar
• Haskell C. M., Canellos G. P., Leventhal B. G., Car-bone P. P., Block J. B. L-asparaginase resistance in human leukemia-asparaginase synthetase. Biochem. Pharmacol. 1969; 18: 2578
   PubMed Web of Science ®Google Scholar
• Capizzi R. L., Cheng Y.-C. Therapy of neo-plasia with asparaginase. Enzymes as Drugs, J. S. Holcenberg, J. Roberts. J. Wiley & Sons, New York 1981; 1
   Google Scholar
• Koishi T., Minowada J., Henderson E. S., Ohnuma T. Distinctive sensitivity of some T-leukemia cell lines to L-asparaginase. Gann 1984; 75: 275
   PubMedGoogle Scholar
• Miller H. K., Salser J. S., Balis M. E. Amino acid levels following L-asparaginase amidohydrolase (EC.3.5.1.1.) therapy. Cancer Res. 1969; 29: 183
   PubMed Web of Science ®Google Scholar
• Prager M. D., Bachynsky N. Asparagine synthetase in normal and malignant tissues; correlation with tumor sensitivity to asparaginase. Arch. Biochem. Biophys. 1968; 127: 645
   PubMed Web of Science ®Google Scholar
• Ho D. H., Brown N. S., Yen A., Holmes R., Keating M., Abuchowski A., Newman R. A., Krakoff I. H. Clinical pharmacology of polyethylene glycol-L-as-paraginase. Drug Metabolism and Disposition 1986; 14: 349
   PubMed Web of Science ®Google Scholar
• Holcenberg J. S., Borella L. D., Camitta B. M., Ring B. I. Human pharmacology and toxicology of succinylated Acinetobacter glutaminase-asparaginase. Cancer Res. 1979; 39: 3145
   PubMed Web of Science ®Google Scholar
• Dolowy W. C., Hensen D. V.M., Cornet J., Sellin H. Toxic and antineoplastic effects of L-asparaginase. Cancer 1966; 19: 1813
   PubMed Web of Science ®Google Scholar
• Oettgen H. F., Old L. J., Boyse E. A., Campbell H. A., Philips F. S., Clarkson B. D., Talial L., Leeper R. D., Schwartz M. K., Kim J. H. Inhibition of leukemias in man by L-asparaginase. Cancer Res. 1967; 27: 2619
   PubMed Web of Science ®Google Scholar
• Crowther D. L-asparaginase and human malignant disease. Nature 1971; 229: 168
   PubMed Web of Science ®Google Scholar
• Clarkson B., Krakoff I., Burchenal J., Karnofsky D., Golbey R., Dowling M., Oettgen H., Lipton A. Clinical results of treatment with E. coli L-asparaginase in adults with leukemia, lymphoma, and solid tumors. Cancer 1970; 25: 279
   PubMedGoogle Scholar
• Poplack D. G., Reaman G. H. Acute lympho-blastic leukemia in childhood. Pediatric Clinic of North America, The Leukemias, D. G. Poplack. W.B. Saunders, Philadelphia 1988; 903–932
   Google Scholar
• Reihm H., Gadner H., Henze G., Langerman H. D., Odenwald E. The Berlin childhood acute lympho-blastic leukemia therapy study, 1970–1976. Am. J. Pediatr. Hematol. 1980; 2: 229
   Google Scholar
• Steinherz P. G., Gaynon P., Miller D. R., Reaman G., Bleyer A., Finklestein J., Evans R. G., Meyers P., Steinherz L. J., Sather H., Hammond D. Improved disease-free survival of children with acute lympho-blastic leukemia at high risk for early relapse with the New York regimen-a new intensive therapy protocols: A report from the Childrens Study Group. J. Clin. Oncol. 1986; 4(5)744
   PubMed Web of Science ®Google Scholar
• Capizzi R. L., Bertino J. R., Handschumacher R. E. L-asparaginase. Ann. Rev. Med. 1970; 21: 433
   PubMed Web of Science ®Google Scholar
• Kay H. E.M., Hamilton-Fairley G., Knapton P. J. The use of different forms of asparaginase with particular reference to Erwinia carotovorum. International Symposium on L-asparaginase. Editions due Centre National de la Recherche Scientifique, Paris 1971; 295
   Google Scholar
• Ohnuma T., Holland J. F., Meyer P. Erwinia carotovora asparaginase in patients with prior anaphylaxis to asparaginase from E. coli. Cancer 1970; 30: 376
   Web of Science ®Google Scholar
• Capizzi R. L. Schedule-dependent synergism and antagonism between methotrexate and asparaginase. Biochem. Pharmacol. 1974; 23(2)151
   Google Scholar
• Schwartz S. A., Morgenstern B., Capizzi R. L. Schedule-dependent synergy and antagonism between high-dose l-β-D-arabinofuranosylcytosine and asparaginase in the L5178Y murine leukemia. Cancer Res. 1982; 42: 2191
   PubMed Web of Science ®Google Scholar
• Capizzi R. L., Keiser L. W., Sartorelli A. C. Combination chemotherapy-Theory and practice. Semin. Oncol. 1977; 4: 227
   PubMed Web of Science ®Google Scholar
• Yap B. S., McCredie K. B., Benjamin R. S., Bodey G. P., Freireich E. J. Refractory acute leukemia in adults treated with sequential collaspase and high-dose methotrexate. Br. Med. J. 1978; 2: 791
   PubMed Web of Science ®Google Scholar
• Capizzi R. L., Davis R., Powell B., Cuttner J., Ellison R. R., Cooper M. R., Dillman R., Major W. B., Dupre E., McIntyre O. R. Synergy between high-dose cytarabine and asparaginase in the treatment of adults with refractory and relapsed acute myelogenous leukemia-a Cancer and Leukemia Group B study. J. Clin. Oncol. 1988; 6: 499
   PubMed Web of Science ®Google Scholar
• Haskell C. M., Canellos G. P., Leventhal B. G., Car-bone P. P., Block J. B. L-asparaginase: therapeutic and toxic effects in patients with neoplastic disease. N. Engl. J. Med. 1969; 2810: 1028
   Web of Science ®Google Scholar
• Clavell L. A., Gelber R. D., Cohen H. J., Hitchcock-Bryan S., Cassady J. R., Tarbell N. J., Blattner S. R., Tantravahi R., Leavitt P., Sallan S. E. Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia. N. Engl. J. Med. 1986; 315: 657
   PubMed Web of Science ®Google Scholar
• Eden O. B., Shaw M. P., Lilleyman J., Richards J. L-asparaginase: Decreased toxicity with Erwinia Asparaginase used in MRC UKALL VLLL. Proc. SIOP, Trondheim. 1988
   Google Scholar
• Fabry U., Korholz D., Jurgens H., Gobel U., Wahn V. Anaphylaxis to L-asparaginase during treatment for acute lymphoblastic leukemia in children-evidence of a complement-mediated mechanism. Pediatr. Res. 1985; 19: 400
   PubMed Web of Science ®Google Scholar
• Ohnuma T., Holland J. F., Freeman A., Sinks L. F. Biochemical and pharmacological studies with asparaginase in man. Cancer Res. 1970; 30: 2297
   PubMed Web of Science ®Google Scholar
• Kurtzberg J., Friedman H., Asselin B., Schultz W., Krischer J., Scudiery D., Franklin A., Finkelberg Z. The use of polyethylene glycol-conjugated L-asparaginase in pediatric patients with prior hypersensitivity to native L-asparaginase. Proc. Am. Soc. Clin. Oncol. 1990; 9: 219, (Abstract)
   Google Scholar
• Lord V. J., Sutow W. W., Fernbach D. J. Toxicity of L-asparaginase in children with advanced leukemia. Cancer 1972; 30: 339
   PubMed Web of Science ®Google Scholar
• Oettgen H. F., Stephenson P. A., Schwartz M. K., Lee-per R. D., Tallal L., Tan C. C., Clarkson B. D., Gol-bey R. B., Krakof I. H., Karnofsky D. A., Murphy M. L., Burchenal J. H. Toxicity of E. coli L-asparaginase in man. Cancer 1970; 25: 253
   PubMedGoogle Scholar
• Whitecar J. P., Jr., Bodey G. P., Harris J. E., Freireich E. J. Current concepts: L-asparaginase. N. Engl. J. Med. 1969; 282: 732
   Web of Science ®Google Scholar
• Barbui T., Finazzi G., Vigano S., Mannucci P. M. L-asparaginase lowers protein C antigen. Thromb. Haemostas. 1984; 52: 216
   PubMed Web of Science ®Google Scholar
• Cappellato M. G., Rosolen A., Zanesco L., Girolami A. Clotting complications of L-asparaginase therapy in children with ALL. Blut. 1986; 52: 377
   PubMedGoogle Scholar
• Casonato A., Lazzaro A. R., Rosolen A., Girolami A. Factor VIII/von Willebrand factor abnormalities during L-asparaginase treatment in patients with acute lymphoblastic leukemia. Acta. Hematol. 1988; 80: 190
   PubMed Web of Science ®Google Scholar
• Homans A. C., Rybak M. E., Baglini R. L., Tiarks C., Steiner M. E., Forman E. N. Effect of L-asparaginase administration on coagulation and platelet function in children with leukemia. J. Clin. Oncol. 1987; 5: 811
   PubMed Web of Science ®Google Scholar
• Greenstein R., Nogeire C., Ohnuma T., Greenstein A. Management of asparaginase-induced hemor-rhagic pancreatitis complicated by pseudocyst. Cancer 1979; 43: 718
   PubMed Web of Science ®Google Scholar
• Samuels B. I., Culbert S. J., Okamura J. Early detection of chemotherapy-related pancreatic enlargement in children using abdominal sonography. Cancer 1976; 38: 1976
   Web of Science ®Google Scholar
• Jenkins R., Perlin E. Severe hepatotoxicity from escherichia coli-L-asparaginase. J. Natl. Med. Assoc. 1987; 79: 775
   PubMed Web of Science ®Google Scholar
• Pochedly C. Neurotoxicity due to CNS therapy for leukemia. Med. Pediat. Oncol. 1972; 3: 101
   Google Scholar
• Ho D. H.W., Wang C.-Y., Lin J.-R., Brown N., Newman R. A., Krakoff I. H. Polyethylene glycol-L-asparaginase and L-asparaginase studies in rabbits. Drug Metabolism and Disposition 1988; 16: 27
   PubMed Web of Science ®Google Scholar
• Nesbit M., Chard R., Evans A., Karon M., Hammond G. D. Evaluation of intramuscular versus intravenous administration of L-asparaginase in childhood leukemia. Am. J. Pediatr. Hematol. 1979; 1: 9
   PubMedGoogle Scholar
• Desai S. J., Barr R. D., Andrew M., De Veber L. L., Pai M. K.R. Management of Ontario children with acute lymphoblastic leukemia by the Dana-Farber Cancer Institute protocols. Canad. Med. Assoc. J. 1989; 141: 693
   Web of Science ®Google Scholar