10
Views
7
CrossRef citations to date
0
Altmetric
Original Article

Terminal Transferase Expression in the Differential Diagnosis of Acute Leukemias

, , , &
Pages 265-269 | Received 08 Oct 1995, Published online: 01 Jul 2009

References

  • Paietta E. Immunobiology of Acute Leukemia. Neoplastic Diseases of the Blood3rd Edition., P.H. Wiernik, G.P. Canellos, R.A. Kyle, J.P. Dutcher. Churchill Livingstone, New York 1995; 211–247
  • Bollum F.J. Terminal deoxynucleotidyl transferase as a hematopoietic cell marker. Blood 1979; 54: 1203–1215
  • Marks S.M., Baltimore D., McCaffrey R. Terminal transferase as a predictor of initial responsiveness to vincristine and prednisone in blastic chronic myelogenous leukemia. N. Engl. J. Med. 1978; 298: 812
  • Drexler H.G., Sperling C., Ludwig W.-D. Terminal deoxynucleotidyl transferase (TdT) expression in acute myeloid leukemia. Leukemia 1993; 7: 1142–1150
  • Paietta E., Van Ness B., Bennett J., Racevskis J., Gucalp R., Cassileth P., Wiernik P.H. Lymphoid lineage-associated features in acute myeloid leukemia: Phenotypic and genotypic correlations. Br. J. Haemalol 1992; 82: 324–331
  • Gucalp R., Paietta E., Weinberg V., Papenhausen P., Dutcher J.P., Wiernik P.H. Terminal transferase expression in acute myeloid leukemia: Biology and prognosis. Br. J. Haematol 1991; 77: 48–54
  • Paietta E., Meenan B., Heavey C., Thomas D. Detection of terminal transferase in acute myeloid leukemia by flow cytometry. Cytometry 1994; 16: 256–261
  • Paietta E., Racevskis J., Bennett J.M., Wiernik P.H. Differential expression of terminal transferase (TdT) in acute lym-phocytic leukemia expressing myeloid antigens and TdT positive acute myeloid leukemia as compared to myeloid antigen negative acute lymphocytic leukemia. Br. J. Haematol 1993; 84: 416–422
  • Hirata M., Okamoto Y. Enumeration of terminal deoxynucleotidyl transferase positive cells in leukemia/lymphoma by flow cytometry. Leukemia Res. 1987; 11: 509–518
  • Drach J., Gattringer C., Huber H. Combined flow cy-tometric assessment of cell surface antigens and nuclear TdT for the detection of minimal residual disease in acute leukemia. Br. J. Haematol 1991; 77: 37–42
  • Farahat N., Lens D., Morilla R., Matutes E., Catovsky D. Differential TdT expression in acute leukemia by flow cytometry: A quantitative study. Leukemia 1995; 9: 583–587
  • Bardales R.H., Carrato A., Fleischer M., Schwartz M.K., Koziner B. Detection of terminal deoxynucleotidyl transferase (TdT) by flow cytometry in leukemic disorders. J. Histochem. Cytochem. 1989; 37: 509–513
  • Loftin K.C., Reuben J.M., Dalton W., Hersh E.M., Sujansky D. Terminal transferase in leukemias by flow cytometry. Diagn. Immunol. 1986; 4: 165–169
  • Slaper-Cortenbach I. C. M., Admiraal L.G., Kerr J.M., van Leeuwen E.F., von dem Borne A. E. G. Kr., Tetteroo P. A. T. Flow-cytometric detection of terminal deoxynucleotidyl transferase and other intracellular antigens in combination with membrane antigens in acute lymphatic leukemias. Blood 1988; 72: 1639–1644
  • Gore S.D., Kastan M.B., Civin C.I. Normal human bone marrow precursors that express terminal deoxynucleotidyl transferase include T-cell precursors and possible lymphoid stem cells. Blood 1991; 77: 1681–1690
  • Syrjala M.T., Tiirikainen M., Jansson S.-E., Krusius T. Flow cytometric analysis of terminal deoxynucleotidyl transferase. A simplified method. Am. J. Clin. Pathol 1993; 99: 298–303
  • Hechinger M.K., Hernandez A.M., Barr N.J., Parker J.W. A clinical laboratory approach to the evaluation of terminal deoxynucleotidyl transferase (TdT) by flow cytometry (FCM). J. Clin. Lab. Ana. 1994; 8: 211–218
  • Pizzolo G., Vincenzi C., Nadali G., Veneri D., Vinante F., Chilosi M., Basso G., Connelly M.C., Janossy G. Detection of membrane and intracellular antigens by flow cytometry following ORTHO PermeafixTM fixation. Leukemia 1994; 8: 672–676
  • Horvatinovich J.M., Sparks S.D., Borowitz M.J. Detection of terminal deoxynucleotidyl transferase by flow cytometry: A three color method. Commun. Clin. Cytometry 1994; 18: 228–230
  • Serke S. Detection of terminal deoxynucleotidyl transferase by permeabilization of cells using a standard red blood cell lyse reagent. Cytometry 1995; 19: 189–190
  • Caldwell C.W. Preservation of B-cell associated surface antigens by chemical fixation. Cytometry 1994; 16: 243–249
  • Murray M., Heavey C., Paietta E. ORTHO PermeafixTM fixation is not suitable for the flow cytometric detection of nuclear terminal transferase in acute myeloid leukemia cells. Leukemia 1995; 9: 226–227
  • Paietta E., Van Ness B., Bennett J.M., Pellone C., Billadeau D., Cassileth P.A., Wiernik P.H. Unexpected im-munoglobulin light chain gene rearrangements in myeloid antigen positive acute lymphoid leukemia. Leukemia Res. 1991; 15: 149–155
  • Paietta E., Andersen J., Gallagher R., Bennett J., Yunis J., Cassileth P., Rowe J., Wiernik P.H. The immunophe-notype of acute promyelocytic leukemia (APL): An ECOG study. Leukemia 1994; 8: 1108–1112
  • Knapp W., Strobl H., Majdic O. Flow cytometric analysis of cell-surface and intracellular antigens in leukemia diagnosis. Commun. Clin. Cytometry 1994; 18: 187–198
  • Bradstock K.F., Janossy G., Hoffbrand A.V., Ganeshaguru K., Llewellin P., Prentice H.G., Bollum F.J. Immunofluorescent and biochemical studies of terminal deoxynucleotidyl transferase in treated acute leukemia. Br. J. Haematol. 1981; 47: 121–131

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.