221
Views
174
CrossRef citations to date
0
Altmetric
Original Article

Selective Delivery of Adiramycin to a Solid Tumor Using a Polymeric Micelle Carrier System

, , , , &
Pages 171-186 | Received 04 Nov 1998, Accepted 06 Apr 1999, Published online: 26 Jun 2009

References

  • Abchowski A., McCoy J. R., Palczuk N. C., van Es T., Davis F. F. Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. J. Biol. Chem. 1977; 252: 3582–3586
  • Cummings J., Merry S., Willmott N. Disposition kinetics of adriamycin, adriamycinol and their 7-deoxyglycones in AKR mice bearing a sub-cutaneously growing ridg-way osteogenic sarcoma (ROS). Eur. J. Cancer Clin. Oncol. 1986; 22: 451–460
  • de Leeuw A. M., Brouwer A., Knook D. L. Sinusoidal endothelial cells of the liver: Fine structure and function in relation to age. J. Electron Microscopy Technique 1990; 14: 218–236
  • Dvorak H. F., Brown L. F., Detmar M., Dvorak A. M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol. 1995; 146: 1029–1039
  • Duncan R., Dimitrijevic S., Evagorou E. G. The role of polymer conjugates in the diagnosis and treatment of cancer. S. T. P. Pharma. Sci. 1996; 6: 237–263
  • Forssen E. A., Coulter D. M., Proffitt R. T. Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors. Cancer Res. 1992; 52: 3255–3261
  • Gabizon A., Price D. C., Huberty J., Bresalier R. S., Papahadjopoulos D. Effect of liposome composition and other factors on the targeting of liposomes to experimental tumors: Biodistribution and imaging studies. Cancer Res. 1990; 50: 6371–6378
  • Huang S. K., Mayhew E., Gilani S., Lasic D. D., Martin F. J., Papahadjopoulos D. Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon tumor. Cancer Res. 1992; 52: 6774–6781
  • Kabanov A. V., Batrakova E. V., Melik-Nubarov Fedoseev N. A., Dorodnich T. Y., Alakhov V. Y., Chekhonin V. P., Nazarova I. R., Kabanov V. A.A. A new class of drug carriers: Micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain. J. Contr. Rel. 1992; 22: 141–158
  • Katre N. V., Knauf M. J., Laird W. J. Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc. Natl. Acad. Sci. (USA) 1987; 84: 1487–1491
  • Kohn S., Nagy J. A., Dvorak H. F., Dvorak A. M. Pathways of macromolecular tracer transport across venules and small veins: Structural basis for the hyperpermeability of tumor blood vessels. Lab. Invest. 1992; 67: 596–607
  • Kopccck J., Rejmanova P., Chytry V. Polymers containing enzymatically degradable bonds, 1. Chymotrypsin catalysed hydrolysis of p-nitroanilides of phenylalanine and tyrosine attached to side-chains of copolymers of N-(2-hydroxy-propyl)methacrylamide. Makromol. Chem. 1981; 182: 799–801
  • Kwon G. S., Yokoyama M., Okano T., Sakurai S., Kataoka K. Biodistribution of micelle-forming polymer-drug conjugates. Pharm. Res. 1993; 10: 970–974
  • Kwon G. S., Yokoyama M., Okano T., Sakurai S., Kataoka K. Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly(ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J. Contr. Rel. 1994a; 29: 17–23
  • Kwon G. S., Naito M., Kataoka K., Yokoyama M., Sakurai Y., Okano T. Block copolymer micelles as vehicles for hydrophobic drugs. Colloids and Surfaces B: Biointerfaces 1994b; 2: 429–434
  • Kwon G. S., Naito M., Kataoka K., Yokoyama M., Okano T., Sakurai Y. Physical entrapment of doxorubicin in AB block copolymer micelles. Pharm. Res. 1995; 12: 192–195
  • Kwon G. S., Naito M., Yokoyama M., Okano T., Sakurai Y., Kataoka K. Block copolymer micelles for drug delivery: Loading and release of doxorubicin. J. Contr. Rel. 1997; 48: 195–201
  • Lasic D. D., Martin F. J., Gabizon A., Huang S. K., Papahadjopoulos D. Sterically stabilized liposomes: A hypothesis on the molecular origin of the extended circulation times. Biochim. Biophys. Acta 1991; 1070: 187–192
  • Litzinger D. C., Buiting A. M.J., van Roojen N., Huang L. Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim. Biophys. Acta 1994; 1190: 99–107
  • Maeda H., Seymour L. W., Miyamoto Y. Conjugates of anticancer agents and polymers: Advantages of macromolec-ular therapeutics in vivo. Bioconjugate Chem. 1992; 3: 351–362
  • Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 1986; 46: 6387–6392
  • McCready D. R., Balch C. M., Fidler I. J., Murray J. L. Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo. J. Natl. Cancer. Inst. 1989; 81: 682–687
  • Pai L. H., Wittes R., Setser A., Willingham M. C., Pastan I. Treatment of advanced tumors with immunotoxin LMB-1: An antibody linked Pseudomonas exotoxin. Nature Medicine 1996; 2: 350–353
  • Putnam D., Kopecek J. Polymer conjugates with anticancer activity. Adv. Polym. Sci. 1995; 122: 55–123
  • Rolland A., O'mullane J., Goddard P., Brookman L., Petrak K. New macromolecular carriers for drugs. I. Preparation and characterization of poly(oxyethylene-b-iso-prene-b-oxyethylene) block copolymer aggregates. J. Appl. Polym. Sci. 1992; 44: 1195–1203
  • Senger D. R., Galli S. J., Dvorak A. M., Perruzzi C. A., Harvey V. S., Dvorak H. F. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983; 219: 983–985
  • Seymour L. W., Miyamoto Y., Maeda H., Brereton M., Strohalm J., Ulbrich K., Duncan R. Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. Eur. J. Cancer 1995; 31A: 766–770
  • Tardi P. G., Boman NX., Cullis P. R. Review: Liposomal doxorubicin. J. Drug Targeting 1996; 4: 129–140
  • Tomlinson E. (Paso)physiology and the temporal and spatial aspects of drug delivery. Site-Specijic Drug Delivery, E. Tomlinson, S. S. Davis. Wiley & Sons Ltd. 1986; 1–26
  • Trail P. A., Wilner D., Lasch S. J., Henderson A. J., Hofstead H., Casazza A. M., Firestone R. A., Hellström I., Hellström K. E. Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates. Science 1993; 261: 212–215
  • Wish L., Furth J., Storey R. H. Direct determinations of plasma, cell, and organ-blood volumes in normal and hypervolemic mice. Proc. Soc. Exp. Biol. And Med. 1950; 74: 644–648
  • Woodle M. C., Lasic D. D. Sterically stabilized liposomes. Biochim. Biophys. Acta 1992; 1113: 171–199
  • Yesair D. W., Schwartzbach E., Shunk D., Denine E. P., Asbell M. A. Comparative pharamacokinetics of daunomycin and adriamycin in several animal species. Cancer Res. 1972; 32: 1177–1183
  • Yokoyama M., Miyauchi M., Yamada N., Okano T., Sakurai Y., Kataoka K., Inoue S. Characterization and anticancer activity of the micelle-forming polymeric anticancer drug doxorubicin-conjugated poly(ethylene glycol)-poly (aspartic acid) block copolymer. Cancer Res. 1990; 50: 1693–1700
  • Yokoyama M., Okano T., Sakurai Y., Ekimoto H., Shibazaki C., Kataoka K. Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood. Cancer Res. 1991; 51: 3229–3236
  • Yokoyama M., Kwon G. S., Okano T., Sakurai Y., Ekimoto H., Okamoto K., Mashiba H., Seto T., Kataoka K. Composition-dependent in vivo antitumor activity of doxorubicin-conjugated polymeric micelle against murine colon adenocarcinoma 26. Drug Delivery 1993; 1: 11–19
  • Yokoyama M., Okano T., Sakurai Y., Kataoka K. Improved synthesis of doxorubicin-conjugated poly(ethylene oxide)-poly(aspartic acid) block copolymer and formation of unimodal miceilar structure with controlled amount of physically entrapped doxorubicin. J. Contr. Rel. 1994; 32: 269–277
  • Yokoyama M., Okano T. Targetable drug carriers: Present status and a future perspective. Adv. Drug Delivery Rev. 1997; 21: 77–80
  • Yokoyama M., Fukushima S., Vehara R., Okamoto K., Kataoka K., Sakurai Y., Okano T. Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and thier design for in vivo delivery to a solid tumor. J. Contr. Rel. 1998; 50: 79–92

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.