Gadolinium-conjugated PLA-PEG nanoparticles as liver targeted molecular MRI contrast agent

References

• Alexis F, Pridgen E, Molnar LK, Farokhzad OC. (2008). Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm, 5, 505–515.
   PubMed Web of Science ®Google Scholar
• Avgoustakis K. (2004). Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: preparation, properties and possible applications in drug delivery. Curr Drug Deliv, 1, 321–333.
   PubMedGoogle Scholar
• Chen Z, Yu D, Wang S, Zhang N, Ma C, Lu Z. (2009). Biocompatible Nanocomplexes for Molecular Targeted MRI Contrast Agent. Nanoscale Res Lett, 4, 618–626.
   PubMed Web of Science ®Google Scholar
• Cheng J, Teply BA, Sherifi I, Sung J, Luther G, Gu FX, Levy-Nissenbaum E, Radovic-Moreno AF, Langer R, Farokhzad OC. (2007). Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials, 28, 869–876.
   PubMed Web of Science ®Google Scholar
• de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R. (1998). MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology, 208, 65–71.
   PubMed Web of Science ®Google Scholar
• Doiron AL, Chu K, Ali A, Brannon-Peppas L. (2008). Preparation and initial characterization of biodegradable particles containing gadolinium-DTPA contrast agent for enhanced MRI. Proc Natl Acad Sci USA, 105, 17232–17237.
   PubMed Web of Science ®Google Scholar
• Doiron AL, Homan KA, Emelianov S, Brannon-Peppas L. (2009). Poly(lactic-co-glycolic) acid as a carrier for imaging contrast agents. Pharm Res, 26, 674–682.
   PubMed Web of Science ®Google Scholar
• Duarte MG, Gil MH, Peters JA, Colet JM, Elst LV, Muller RN, Geraldes CF. (2001). Synthesis, characterization, and relaxivity of two linear Gd(DTPA)-polymer conjugates. Bioconjug Chem, 12, 170–177.
   PubMed Web of Science ®Google Scholar
• Favier A, D’Agosto F, Charreyre MT, Pichot C. (2004). Synthesis of N-acryloxysuccinimide copolymers by RAFT polymerization, as reactive building blocks with full control of composition and molecular weights. Polymer, 45, 7821–7830.
   Web of Science ®Google Scholar
• Gindy ME, Prud’homme RK. (2009). Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy. Expert Opin Drug Deliv, 6, 865–878.
   PubMed Web of Science ®Google Scholar
• Lin YS, Hung Y, Su JK, Lee R, Chang C, Lin ML, Mou CY. (2004). Gadolinium(III)-incorporated nanosized mesoporous silica as potential magnetic resonance imaging contrast agents. J Phys Chem B, 108, 15608–15611.
   Web of Science ®Google Scholar
• Liu M, Li H, Luo G, Liu Q, Wang Y. (2008). Pharmacokinetics and biodistribution of surface modification polymeric nanoparticles. Arch Pharm Res, 31, 547–554.
   PubMed Web of Science ®Google Scholar
• Liu X, Xu YK, Huang QL. (2004). [Preparation of a novel targeted MR contrast agent Gd-DTPA-streptavidin and exploration of its reaction conditions]. Di Yi Jun Yi Da Xue Xue Bao, 24, 15–17.
   PubMedGoogle Scholar
• Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD. (2003). A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI. Mol Imaging, 2, 324–332.
   PubMedGoogle Scholar
• Moghimi SM, Davis SS. (1994). Innovations in avoiding particle clearance from blood by Kupffer cells: cause for reflection. Crit Rev Ther Drug Carrier Syst, 11, 31–59.
   PubMed Web of Science ®Google Scholar
• Moghimi SM, Hunter AC, Murray JC. (2001). Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev, 53, 283–318.
   PubMed Web of Science ®Google Scholar
• Moghimi SM, Porter CJ, Muir IS, Illum L, Davis SS. (1991). Non-phagocytic uptake of intravenously injected microspheres in rat spleen: influence of particle size and hydrophilic coating. Biochem Biophys Res Commun, 177, 861–866.
   PubMed Web of Science ®Google Scholar
• Nakamura E, Makino K, Okano T, Yamamoto T, Yokoyama M. (2006). A polymeric micelle MRI contrast agent with changeable relaxivity. J Control Release, 114, 325–333.
   PubMed Web of Science ®Google Scholar
• Oja CD, Semple SC, Chonn A, Cullis PR. (1996). Influence of dose on liposome clearance: critical role of blood proteins. Biochim Biophys Acta, 1281, 31–37.
   Google Scholar
• Park JA, Kim HK, Kim JH, Jeong SW, Jung JC, Lee GH, Lee J, Chang Y, Kim TJ. (2010). Gold nanoparticles functionalized by gadolinium-DTPA conjugate of cysteine as a multimodal bioimaging agent. Bioorg Med Chem Lett, 20, 2287–2291.
   PubMed Web of Science ®Google Scholar
• Paschkunova-Martic I, Kremser C, Mistlberger K, Shcherbakova N, Dietrich H, Talasz H, Zou Y, Hugl B, Galanski M, Sölder E, Pfaller K, Höliner I, Buchberger W, Keppler B, Debbage P. (2005). Design, synthesis, physical and chemical characterisation, and biological interactions of lectin-targeted latex nanoparticles bearing Gd-DTPA chelates: an exploration of magnetic resonance molecular imaging (MRMI). Histochem Cell Biol, 123, 283–301.
   PubMed Web of Science ®Google Scholar
• Swanson SD, Kukowska-Latallo JF, Patri AK, Chen C, Ge S, Cao Z, Kotlyar A, East AT, Baker JR. (2008). Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement. Int J Nanomedicine, 3, 201–210.
   PubMed Web of Science ®Google Scholar
• Tessmar JK, Mikos AG, Göpferich A. (2002). Amine-reactive biodegradable diblock copolymers. Biomacromolecules, 3, 194–200.
   PubMed Web of Science ®Google Scholar
• Turner JL, Pan DPJ, Plummer R, Chen ZY, Whittaker AK, Wooley KL. (2005). Synthesis of gadolinium-labeled shell-crosslinked nanoparticles for magnetic resonance imaging applications. Adv Funct Mater, 15, 1248–1254.
   Web of Science ®Google Scholar
• Unger E, Shen DK, Wu GL, Fritz T. (1991). Liposomes as MR contrast agents: pros and cons. Magn Reson Med, 22, 304–308; discussion 313.
   PubMed Web of Science ®Google Scholar
• Wang S, Jarrett BR, Kauzlarich SM, Louie AY. (2007). Core/shell quantum dots with high relaxivity and photoluminescence for multimodality imaging. J Am Chem Soc, 129, 3848–3856.
   PubMed Web of Science ®Google Scholar
• Weinmann HJ, Ebert W, Misselwitz B, Schmitt-Willich H. (2003). Tissue-specific MR contrast agents. Eur J Radiol, 46, 33–44.
   PubMed Web of Science ®Google Scholar
• Xu ZP, Kurniawan ND, Bartlett PF, Lu GQ. (2007). Enhancement of relaxivity rates of Gd-DTPA complexes by intercalation into layered double hydroxide nanoparticles. Chemistry, 13, 2824–2830.
   PubMed Web of Science ®Google Scholar
• Zou W, Liu C, Chen Z, Zhang N. (2009). Studies on bioadhesive PLGA nanoparticles: A promising gene delivery system for efficient gene therapy to lung cancer. Int J Pharm, 370, 187–195.
   PubMed Web of Science ®Google Scholar