98
Views
11
CrossRef citations to date
0
Altmetric
Research Article

A Mass Spectrometric Multicenter Study Supports Classification of Preeclampsia as Heterogeneous Disorder

, , , , , , , & show all
Pages 278-291 | Published online: 14 May 2012

REFERENCES

  • Heitner JC, Koy C, Reimer T, Kreutzer M, Gerber B, Glocker MO. Differentiation of HELLP patients from healthy pregnant women by proteome analysis. J Chromatogr B Analyt Technol Biomed Life Sci 2006; 840:10–19.
  • Koy C, Heitner JC, Woisch R, . Cryodetector mass spectrometry profiling of plasma samples for HELLP diagnosis: An exploratory study. Proteomics 2005; 5:3079–3087.
  • Palmblad M, Tiss A, Cramer R. Mass spectrometry in clinical proteomics – From the present to the future. Proteomics Clin Appl 2009; 3:6–17.
  • Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet 2005; 365:785–799.
  • Steegers EAP, Von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet 2010; 376:631–644.
  • Rath W, Faridi A, Dudenhausen JW. HELLP syndrome. J Perinat Med 2000; 28:249–260.
  • Aquilina J, Barnet A, Thompson O, Harrington K. Second-trimester maternal serum inhibin A concentration as an early marker for preeclampsia. Am J Obstet Gynecol 1999; 181:131–136.
  • Bersinger NA, Smárason AK, Muttukrishna S, Groome NP. Women with preeclampsia have increased serum levels of pregnancy-associated plasma protein A (PAPP-A), inhibin A, activin A and soluble E-selectin. Hypertens Pregnancy 2003; 22:45–55.
  • Cetin I, Cozzi V, Pasqualini F, . Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction. Am J Obstet Gynecol 2006; 194:1347–1353.
  • Huppertz B, Sammar M, Chefetz I, Neumaier-Wagner P, Bartz C, Meiri H. Longitudinal determination of serum placental protein 13 during development of preeclampsia. Fetal Diagn Ther 2008; 24:230–236.
  • Levine RJ, Lam C, Qian C, . Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 2006; 355:992–1005.
  • Levine RJ, Maynard SE, Qian C, . Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004; 350:672–683.
  • Muttukrishna S, Knight PG, Groome NP, Redman CWG, Ledger WL. Activin A and inhibin A as possible endocrine markers for pre-eclampsia. Lancet 1997; 349:1285–1288.
  • Nicolaides KH, Bindra R, Turan OM, . A novel approach to first-trimester screening for early pre-eclampsia combining serum PP-13 and Doppler ultrasound. Ultrasound Obstet Gynecol 2006; 27:13–17.
  • Verlohren S, Galindo A, Schlembach D, . An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia. Am J Obstet Gynecol 2010; 202:161.e1–161.e11.
  • Pecks U, Seidenspinner F, Röwer C, Reimer T, Rath W, Glocker MO. Multifactorial analysis of affinity-mass spectrometry data from serum protein samples: A strategy to distinguish patients with preeclampsia from matching control individuals. J Am Soc Mass Spectrom 2010; 21:1699–1711.
  • Metz CE. Basic principles of ROC analysis. Semin Nucl Med 1978; 8:283–298.
  • Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000; 183:S1–S22.
  • Brown MA, Lindheimer MD, de Swiet M, Van Assche A, Moutquin JM. The classification and diagnosis of the hypertensive disorders of pregnancy: Statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Hypertens Pregnancy 2001; 20:9–14.
  • Mikkat S, Koy C, Ulbrich M, Ringel B, Glocker MO. Mass spectrometric protein structure characterization reveals cause of migration differences of haptoglobin α chains in two-dimensional gel electrophoresis. Proteomics 2004; 4:3921–3932.
  • Lim A, Prokaeva T, McComb ME, Connors LH, Skinner M, Costello CE. Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosis. Protein Sci 2003; 12:1775–1785.
  • Higgins JR, Brennecke SP. Pre-eclampsia – Still a disease of theories? Curr Opin Obstet Gynecol 1998; 10:129–133.
  • Huppertz B. Placental origins of preeclampsia: Challenging the current hypothesis. Hypertension 2008; 51:970–975.
  • Redman CW, Sacks GP, Sargent IL. Preeclampsia: An excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999; 180:499–506.
  • von Dadelszen P, Magee LA, Roberts JM. Subclassification of preeclampsia. Hypertens Pregnancy 2003; 22:143–148.
  • Kadyrov M, Kingdom JCP, Huppertz B. Divergent trophoblast invasion and apoptosis in placental bed spiral arteries from pregnancies complicated by maternal anemia and early-onset preeclampsia/intrauterine growth restriction. Am J Obstet Gynecol 2006; 194:557–563.
  • Reister F, Frank H-G, Kingdom JCP, Macrophage-induced apoptosis limits endovascular trophoblast invasion in the uterine wall of preeclamptic women. Lab Invest 2001; 81:1143–1152.
  • Holzgreve W, Ghezzi F, Di Naro E, Gänshirt D, Maymon E, Hahn S. Disturbed feto-maternal cell traffic in preeclampsia. Obstet Gynecol 1998; 91:669–672.
  • Lo DYM, Leung TN, Tein MSC, . Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia. Clin Chem 1999; 45:184–188.
  • Roberts JM, Hubel CA. The two stage model of preeclampsia: Variations on the theme. Placenta 2009; 30(Suppl. A):S32–S37.
  • Blumenstein M, McMaster MT, Black MA, . A proteomic approach identifies early pregnancy biomarkers for preeclampsia: Novel linkages between a predisposition to preeclampsia and cardiovascular disease. Proteomics 2009; 9:2929–2945.
  • Gharesi-Fard B, Zolghadri J, Kamali-Sarvestani E. Proteome differences of placenta between pre-eclampsia and normal pregnancy. Placenta 2010; 31:121–125.
  • Watanabe H, Hamada H, Yamada N, . Proteome analysis reveals elevated serum levels of clusterin in patients with preeclampsia. Proteomics 2004; 4:537–543.
  • Buhimschi IA, Zhao G, Funai EF, . Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia. Am J Obstet Gynecol 2008; 199(551):551.e1–551.e16.
  • Dickson PW, Howlett GJ, Schreiber G. Metabolism of prealbumin in rats and changes induced by acute inflammation. Eur J Biochem 1982; 129:289–293.
  • Redman CW, Sargent IL. Pre-eclampsia, the placenta and the maternal systemic inflammatory response – A review. Placenta 2003; 24(Suppl A):S21–S27.
  • Abdi H. Bonferroni and Sidak corrections for multiple comparisons. In: Salkind NJ, ed. Encyclopedia of Measurement and Statistics. Thousand Oaks, CA: SAGE Publications, 2007: 103–106.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.