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Research Article

The Genetic Control of Blood Pressure and Body Composition in Rats with Stress-Sensitive Hypertension

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Pages 484-495 | Received 21 Aug 2012, Accepted 06 Nov 2012, Published online: 09 Jan 2013

REFERENCES

  • Henry JP, Liu YY, Nadra WE. Psychosocial stress can induce chronic hypertension in normotensive strains of rats. Hypertension 1993; 21:714–723.
  • Kyrou I, Tsigos C. Chronic stress, visceral obesity and gonadal dysfunction. Hormones (Athens) 2008; 7:287–293.
  • Harshfield GA, Dong Y, Kapuku GK, Zhu H, Hanevold CD. Stress-induced sodium retention and hypertension: a review and hypothesis. Curr Hypertens Rep 2009; 11:29–34.
  • Lin W, Wang W, Shao F. New animal model of emotional stress: behavioral, neuroendocrine and immunological consequences. Chn Sci Bull 2003; 48:1565–1568.
  • Markel AL, Redina OE, Gilinsky MA, . Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension. J Endocrinol 2007; 195:439–450.
  • Tamashiro KL, Nguyen MM, Ostrander MM, . Social stress and recovery: implications for body weight and body composition. Am J Physiol Regul Integr Comp Physiol 2007; 293:R1864–R1874.
  • de Souza DB, Silva D, Silva CMC, Sampaio FJB, Costa WS, Cortez CM. Effects of immobilization stress on kidneys of Wistar male rats: a morphometrical and stereological analysis. Kidney Blood Press Res 2011; 34:424–429.
  • Adarichev VA, Korokhov NP, Ostapchuk IaV, Dymshits GM, Markel AL. Characterization of rat lines with normotensive and hypertensive status using genomic fingerprinting. Genetika 1996; 32:1669–1672.
  • Markel AL. Development of a new strain of rats with inherited stress-induced arterial hypertension. In: Sassard J, ed. Genetic Hypertension. London: Colloque INSERM; 1992:405–407.
  • Markel AL, Maslova LN, Shishkina GT, Bulygina VV, Machanova NA, Jacobson GS. Developmental influences on blood pressure regulation in ISIAH rats. In: McCarty R, Blizard DA, Chevalier RL, eds. Development of the Hypertensive Phenotype: Basic and Clinical Studies. Amsterdam- Lausanne- NewYork- Oxford- Shannon- Singapore- Tokyo: Elsevier; 1999:493–526.
  • Shmerling MD, Filiushina EE, Lazarev VA, Buzueva II, Markel AL, Iakobson GS. Ultrastructural changes of kidney corpuscles in rats with hereditary stress-induced arterial hypertension [Article in Russian]. Morfologiia 2001; 120:70–74.
  • Yakobson GS, Shmerling MD, Fillyushina EE, . Morpho-physiological aspects of effectiveness of preventive action of antihypertensive drugs on arterial pressure and target organs in the rats with inherited hypertension. Byul. SO RAMN 2007; 3:142–147.
  • Redina OE, Machanova NA, Efimov VM, Markel AL. Rats with inherited stress-induced arterial hypertension (ISIAH strain) display specific quantitative trait loci for blood pressure and for body and kidney weight on chromosome 1. Clin Exp Pharmacol Physiol 2006; 33:456–464.
  • Redina OE, Smolenskaya SE, Maslova LN, Markel AL. Genetic control of the corticosterone level at rest and under emotional stress in ISIAH rats with inherited stress-induced arterial hypertension. Clin Exp Hypertens 2010; 32:364–371.
  • Rapp JP. Genetic analysis of inherited hypertension in the rat. Physiol Rev 2000; 80:135–172.
  • Kovacs P, Voigt B, Kloting I. Congenic strain confirms putative quantitative trait locus for body weight in the rat. Mamm Genome 1998; 9:294–296.
  • Moreno C, Dumas P, Kaldunski ML, . Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Physiol Genomics 2003; 15:243–257.
  • Bilusic M, Bataillard A, Tschannen MR, . Mapping the genetic determinants of hypertension, metabolic diseases, and related phenotypes in the Lyon hypertensive rat. Hypertension 2004; 44:695–701.
  • Herrera VL, Tsikoudakis A, Ponce LR, Matsubara Y, Ruiz-Opazo N. Sex-specific QTLs and interacting loci underlie salt-sensitive hypertension and target organ complications in Dahl S/jrHS hypertensive rats. Physiol Genomics 2006; 26:172–179.
  • Garrett MR, Joe B, Yerga-Woolwine S. Genetic linkage of urinary albumin excretion in Dahl salt-sensitive rats: influence of dietary salt and confirmation using congenic strains. Physiol Genomics 2006; 25:39–49.
  • Solberg LC, Baum AE, Ahmadiyeh N, . Genetic analysis of the stress-responsive adrenocortical axis. Physiol Genomics 2006; 27:362–369.
  • Tinnikov AA, Bazhan NM. Determination of glucocorticoids in blood and adrenal gland cultures by competitive protein binding without preliminary extraction. Lab Delo 1984; 12:709–713.
  • Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. CSHL Press: Cold Spring Harbor; 1989.
  • Lander ES, Green P, Abrahamson J, . MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1987; 1:174–181.
  • Basten CJ, Weir BS, Zeng Z-B. Zmap-a QTL cartographer. In: Smith C, Gavora JS, Benkel B, ., eds. Proceedings of the 5th World Congress on Genetics Applied to Livestock Production: Computing Strategies and Software. Guelph, Ontario, Canada: Organizing Committee, 5th World Congress on Genetics Applied to Livestock Production; 1994: 65–66.
  • Basten CJ, Weir BS, Zeng Z-B. QTL Cartographer, Version 1.17. Raleigh, NC: Department of Statistics, North Carolina State University; 2004.
  • Churchill GA, Doerge RW. Empirical threshold values for quantitative trait mapping. Genetics 1994; 138:963–971.
  • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995; 11:241–247.
  • Garrett MR, Dene H, Rapp JP. Time-course genetic analysis of albuminuria in Dahl salt-sensitive rats on low-salt diet. J Am Soc Nephrol 2003; 14:1175–1187.
  • Ueno T, Tremblay J, Kunes J, . Gender-specific genetic determinants of blood pressure and organ weight: pharmacogenetic approach. Physiol Res 2003; 52:689–700.
  • Seda O, Liska F, Krenova D, . Dynamic genetic architecture of metabolic syndrome attributes in the rat. Physiol Genomics 2005; 21:243–252.
  • Iwai N, Kinoshita M, Shimoike H. Chromosomal mapping of quantitative trait loci that influence renal hemodynamic functions. Circulation 1999; 100:1923–1929.
  • Lopez B, Ryan RP, Moreno C, . Identification of a QTL on chromosome 1 for impaired autoregulation of RBF in fawn-hooded hypertensive rats. Am J Physiol Renal Physiol 2006; 290:F1213–1221.
  • Tanomura H, Miyake T, Taniguchi Y, . Detection of a quantitative trait locus for intramuscular fat accumulation using the OLETF rat. J Vet Med Sci 2002; 64:45–50.
  • Kloting I, Kovacs P, Van den Brandt J. Sex-specific and sex-independent quantitative trait loci for facets of the metabolic syndrome in WOKW rats. Biochem Biophys Res Commun 2001; 284:150–156.
  • Kovacs P, Kloting I. Mapping of quantitative trait loci for body weight on chromosomes 1 and 4 in the rat. Biochem Mol Biol Int 1998; 44:399–405.
  • Kovacs P, van den Brandt J, Kloting I. Genetic dissection of the syndrome X in the rat. Biochem Biophys Res Commun 2000; 269:660–665.
  • Siegel AK, Planert M, Rademacher S, . Loci contribute to the progression of vascular and cardiac hypertrophy in salt-sensitive spontaneous hypertension. Arterioscler Thromb Vasc Biol 2003; 23:1211–1217.
  • Toland EJ, Yerga-Woolwine S, Farms P, Cicila GT, Saad Y, Joe B. Blood pressure and proteinuria effects of multiple quantitative trait loci on rat chromosome 9 that differentiate the spontaneously hypertensive rat from the Dahl salt-sensitive rat. J Hypertens 2008; 26:2134–2141.
  • Bergamini C, Cicoira M, Rossi A, Vassanelli C. Oxidative stress and hyperuricaemia: pathophysiology, clinical relevance, and therapeutic implications in chronic heart failure. Eur J Heart Fail 2009; 11:444–452.
  • Tsutsui H, Kinugawa S, Matsushima S. Oxidative stress and heart failure. Am J Physiol Heart Circ Physiol 2011; 301:H2181–H2190.
  • Yagil C, Sapojnikov M, Kreutz R, Zu”rcher H, Ganten D, Yagil Y. Role of chromosome X in the Sabra rat model of salt-sensitive hypertension. Hypertension 1999; 33:261–265.
  • Kitiyakara C, Chabrashvili T, Chen Y, . Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol 2003; 14:2775–2782.
  • de Cavanagh EM, Ferder LF, Ferder MD, Stella IY, Toblli JE, Inserra F. Vascular structure and oxidative stress in salt-loaded spontaneously hypertensive rats: effects of losartan and atenolol. Am J Hypertens 2010; 23:1318–1325.
  • Dohanics J, Kovacs KJ, Folly G, Makara GB. Long-term salt loading impairs pituitary responsiveness to ACTH secretagogues and stress in rats. Peptides 1990; 11:59–63.
  • Amaya F, Tanaka M, Hayashi S, Tanaka Y, Ibata Y. Hypothalamo-pituitary-adrenal axis sensitization after chronic salt loading. Neuroendocrinology 2001; 73:185–193.
  • Gavras I, Gavras H. ‘Volume-expanded’ hypertension: the effect of fluid overload and the role of the sympathetic nervous system in salt-dependent hypertension. J Hypertens 2012; 30:655–659.
  • Ahmadiyeh N, Churchill GA, Shimomura K, Solberg LC, Takahashi JS, Redei EE. X-linked and lineage-dependent inheritance of coping responses to stress. Mamm Genome 2003; 14:748–757.
  • Xiao B, Harada Y, Kawakami K, Nabika T. A 1.8-Mbp fragment on chromosome 1 affects sympathetic response to stress: evaluation in reciprocal congenic strains between stroke-prone spontaneously hypertensive rat and Wistar-Kyoto rat. J Hypertens 2011; 29:257–265.
  • Ahmadiyeh N, Churchill GA, Solberg LC, . Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Behav Genet 2005; 35:189–198.
  • Gauguier D, Behmoaras J, Argoud K, . Chromosomal mapping of quantitative trait loci controlling elastin content in rat aorta. Hypertension 2005; 45:460–466.
  • Ways JA, Smith BM, Barbato JC, . Congenic strains confirm aerobic running capacity quantitative trait loci on rat chromosome 16 and identify possible intermediate phenotypes. Physiol Genomics 2007; 29:91–97.
  • Legare ME, Bartlett FS 2nd, Frankel WN. A major effect QTL determined by multiple genes in epileptic EL mice. Genome Res 2000; 10:42–48.
  • Morel L, Blenman KR, Croker BP, Wakeland EK. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc Natl Acad Sci 2001; 98:1787–1792.
  • Karlsen FM, Andersen CB, Leyssac PP, Holstein-Rathlou N-H. Dynamic autoregulation and renal injury in Dahl rats. Hypertension 1997; 30:975–983.
  • Feld LG, Van Liew JB, Galaske RG, Boylan JW. Selectivity of renal injury and proteinuria in the spontaneously hypertensive rat. Kidney Int 1977; 12:332–343.
  • Atchley WR, Wei R, Crenshaw P. Cellular consequences in the brain and liver of age-specific selection for rate of development in mice. Genetics 2000; 155:1347–1357.
  • Samani NJ, Gauguier D, Vincent M, . Analysis of quantitative trait loci for blood pressure on rat chromosomes 2 and 13. Age-related differences in effect. Hypertension 1996; 28:1118–1122.
  • Carlborg O, Kerje S, Schűtz K, Jacobsson L, Jensen P, Andersson L. A global search reveals epistatic interaction between QTL for early growth in the chicken. Genome Res 2003; 13:413–421.
  • Beck SR, Brown WM, Williams AH, Pierce J, Rich SS, Langefeld CD. Age-stratified QTL genome scan analyses for anthropometric measures. BMC Genet 2003; 4:S31.

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