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Clinical and Experimental Hypertension Volume 3, 1981 - Issue 2
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Original Article

Plasma Substance P Levels in Normotensive and Hypertensive Subjects

W. B. Campbell Department of Pharmacology, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235; Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235
,
O. B. Holland Department of Pharmacology, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235; Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235
,
C. E. Gomez-Sanchez Department of Pharmacology, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235; Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235
,
R. M. Graham Department of Pharmacology, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235; Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235
,
W. A. Pettinger Department of Pharmacology, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235; Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235
&
A. C. White Department of Pharmacology, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235; Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Blvd, Dallas, TX, 75235
Pages 183-193 | Published online: 03 Jul 2009

References

  • Ardenshorst W. J., Cook M. A., Mills I. H. Effect of substance P on proximal tubular reabsorption in the rat. Am. J. Physiol. 1976; 230: 1662
  • Campbell W. B., Ward P. E. Renal metabolism of substance P in the dog. Life Sci. 1995; 24, 1979
  • Goldstein A. Biostatistics An Introductory Text. MacMillan, Inc., New York 1964
  • Goodfriend T. L., Levine L., Fasman G. D. Antibodies to bradykinin and angiotensin: A use of carbodiimides in immunology. Science 1964; 144: 1344
  • Gullner H.-G., Campbell W. B., Pettinger W. A. Effects of substance P on renin release and renal function in anesthetized dogs. Life Sci. 1979; 24: 237
  • Gullner H.-G., Campbell W. B., Pettinger W. A. Role of substance P in water homeostasis. Life Sci. 1979; 24: 2351
  • Hallberg D., Pernow B. Effect of substance P on various vascular beds in the dog. Acta Physiol. Scand. 1975; 93: 277
  • Holland O. B., Chud J. M., Braunstein H. Urinary kallikrein excretion in essential and mineralocorticoid hypertension. J. Clin. Invest. 1980; 65: 347
  • Kaplan W. M., Kem D. C., Holland D. B., Kramer N. J., Higgins J. R., Gomez-Sanchez C. E. The intravenous furosemide test: A simple way to evaluate renin responsiveness. Ann. Intern. Med. 1974; 133: 205
  • Langan R., Jackson R., Adlin E. V., Channick B. J. A simple radioimmunoassay for urinary aldosterone. J. Clin. Endocrinol. Metab. 1974; 38: 189
  • Lembeck F., Holzer P., Schweditsch M., Gamse R. Elimination of substance P from the circulation of the rat and its inhibition by bacitracin. Nauyn-Schmiedebergs Arch. Pharmacol. 1978; 305: 9
  • Mashford M. L., Roberts M. L. Determination of blood kinin levels by radioimmunoassay. Biochem. Pharmacol. 1972; 21: 2727
  • McConahey P. J., Dixon F. J. A method of trace iodination of proteins for immunologic studies. Int. Arch. Allergy 1966; 29: 195
  • Mills I. H., Macfarlane N. A. A., Ward P. E. Increase in kallikrein excretion during the natriuresis produced by arterial infusion of substance P. Nature 1974; 247: 108
  • Nilsson G., Pernow B., Fischer G. H., Folkers K. Presence of substance P-like immunoreacitivity in plasma from man and dog. Acta Physiol. Scand. 1975; 94: 542
  • Skrabanek P., Cannon D., Kirrane J., Powell D. Substance P secretion by carcinoid tumours. Irish J. Med. Sci. 1978; 147: 47
  • Skrabanek P., Cannon D., Kirrane J., Legge D., Powell D. Circulating innumoreactive substance P in man. Irish J. Med. Sci. 1976; 145: 399
  • VonEuler U. S., Gaddum J. H. An unidentified depressor substance in certain tissue extracts. J. Physiol. Lond. 1931; 72: 74
  • Yanaihara C., Sato H., Hirohashi M., Sakagami M., Yamaoto K., Hashimoto T., Yanaihara N., Abe K., Kaneko T. Substance P radioimmunossay using Nα-tyrosyl-substance P and demonstration of the presence of substance P-like immuno-reactivities in human blood and porcine tissue extracts. Endocrinol. Japan 1976; 23: 457

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