Impact of cardiovascular risk factors on oxidative stress and DNA damage in a high risk Mediterranean population

References

• Dalle-Donne I, Rossi R, Colombo R, Giustarini D, Milzani A. Biomarkers of oxidative damage in human disease. Clin Chem 2006;52:601–623.
   PubMed Web of Science ®Google Scholar
• Ungvari Z, Parrado-Fermamdez C, Csoszar A, de Caba R. Mechanisms urderlying caloric restriction and lifespan regulation. Implication for vascular aging. Circ Res 2008;102:519–528.
   PubMedGoogle Scholar
• Fung TT, Rexrode KM, Mantzoros CS, Manson JE, Willett WC, Hu FB. Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women. Circulation 2009;119:1093–1100.
   PubMed Web of Science ®Google Scholar
• Konhilas JP, Leinwand LA. The effect of biological sex and diet on the development of heart failure. Circulation 2007;116:2747–2759.
   PubMed Web of Science ®Google Scholar
• Romero JC, Reckelhoff JF. Role of angiotensin and oxidative stress in essential hypertension. Hypertension 1999;34:943–949.
   PubMed Web of Science ®Google Scholar
• Redón J, Oliva MR, Tormos C, Giner V, Chaves J, Iradi A, Sáez GT. Antioxidant activities and oxidative byproducts in human hypertension. Hypertension 2003;41:1096–2001.
   PubMed Web of Science ®Google Scholar
• Murray CJL, Lopez AD. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injures and risk factors in 1990 and projected to 2020. Boston: Harvard School of Public Health; 1999.
   Google Scholar
• Greenland P, Knoll MD, Stamler J, Neaton JD, Dyer AR, Garside DB, Wilson PW. Major risk factors as antecedents of fatal and nonfatal coronary heart disease events. JAMA 2003;290:891–897.
   PubMed Web of Science ®Google Scholar
• Rahman I, Skwarska E, Henry M, Davis M, O'Connor CM, FitzGerald MX, Greening A, MacNee W. Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis. Free Radic Biol Med 1999;27:60–68.
   PubMed Web of Science ®Google Scholar
• Sutherland WH, Manning PJ, Walker RJ, de Jong SA, Ryalls AR, Berry EA. Vit E supplementation and plasma 8-isoprostane and adiponectin in overweight subjects. Obesity 2007;15:386–391.
   PubMed Web of Science ®Google Scholar
• Urakawa H, Katsuki A, Sumida Y, Gabazza EC, Murashima S, Morioka K, Maruyama N, Kitagawa N, Tanaka T, Hori Y, Nakatani K, Yano Y, Adachi Y. Oxidative stress is associated with adiposity and insulin resistance in men. J Clin Endocrinol Metab 2003;88:4673–4676.
   PubMed Web of Science ®Google Scholar
• Holvoet P, Kritchervsky SB, Tracy RP, Mertens A, Rubin SM, Butler J, Goodpaster B, Harris TB. The metabolic syndrome, circulating oxidized LDL, and risk of myocardial infarction in well-functioning elderly people in the health, aging, and body composition cohort. Diabetes 2004;53:1068–1073.
   PubMed Web of Science ®Google Scholar
• Blankenberg S, Rupprecht HJ, Bickel Ch, Torzewski M, Hafner G, Tiret L, Smieja M, Cambien F, Meyer J, Lackner KJ. AtheroGene investigators. Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease. N Engl J Med 2003;349:1605–1613.
   PubMed Web of Science ®Google Scholar
• Tsimikas S, Brilakis ES, Miller ER, McConnell JP, Lennon RJ, Kornman KS, Witztum JL, Berger PB. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med 2005;353:46–57.
   PubMed Web of Science ®Google Scholar
• Abdilla N, Tormos MC, Fabia MJ, Chaves FJ, Saez G, Redon J. Impact of the components of metabolic sindrome on oxidative stress and enzymatic antioxidant activity in essential hypertension. J Human Hyperten 2007;21:68–75.
   Google Scholar
• Estruch R, Martinez-Gonzalez MM, Corella D, Salas-Salvadó J, Ruiz-Gutierrez V, Covas MI, Fiol M, Gómez-Gracia E, López-Sabater MC, Vinyoles E, Arós F, Conde M, Lahoz C, Lapetra J, Sáez G, Ros E, for the PREDIMED study investigators. Effects of a mediterranean-style diet on cardiovascular risk factors. Ann Intern Med 2006;145:1–11.
   PubMed Web of Science ®Google Scholar
• Weinbrenner T, Fito M, De la Torre R, Sáez GT, Rijken Ph., Tormos C, Coolen S, De La Torre R, Covas MI. Olive oils high in phenolic compounds modulate oxidative/antioxidative status in men. J Nutr 2004;134:2314–2321.
   PubMed Web of Science ®Google Scholar
• Sáez GT, Tormos C, Giner V, Chaves J, Lozano JV, Iradi A, Redón J. Factors related to the impact antihypertensive treatment in antioxidant activities and oxidative stress by-products in human hypertension. Am J Hypertens 2004;17:809–816.
   PubMed Web of Science ®Google Scholar
• Espinosa O, Jimenez-Almazan J, Chaves FJ, Tormos MC, Clapes S, Iradi A, Salvador A, Fandos M, Redón J, Sáez GT. Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) a reliable oxidative stress marker in hypertension. Free Radic Res 2007;41:546–554.
   PubMed Web of Science ®Google Scholar
• Polidori MC, Mecocci P, Stahl W, Sies H. Cigarrete smoking cessation increases plasma levels of severel antioxidant micronutrients and improves resistance towards oxidative stress. Br J Nutr 2003;90:147–150.
   PubMed Web of Science ®Google Scholar
• Cooke MS, Evans MD, Herbert KE, Lunec J. Urinary 8-oxo-2′-deoxyguanosine: source, significance and supplements. Free Radic Biol Med 2000;32:381–397.
   Google Scholar
• Chenk KC, Cahill DS, Kasai H, Nishimura S, Loeb LA. 8-hydroxyguanine, an abundant form of oxidative DNA damage, causes G to T and A to C substitutions. J Biol Chem 1992;267:166–172.
   Google Scholar
• Martínez-González MA, Fernández-Jarne E, Serrano-Martinez M, Wright M, Gómez-García E. Development of a short dietary intake questionnaire for quantitative estimation of adherence to a cardioprotective Mediterranean diet. Eur J Clin Nutr 2004;58:1550–1552.
   PubMed Web of Science ®Google Scholar
• Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Scan J Clin Lab Invest 1968;21:77–89.
   PubMed Web of Science ®Google Scholar
• Greenwald RA. Handbook of methods for oxygen radical research. Boca Raton, FL: CRC Press Inc; 1987.
   Google Scholar
• Muñiz P, Valls V, Perez-Broseta C, Iradi A, Climent JV, Oliva MR, Saez GT. The role of 8-hydroxy -2′-deoxyguanosine in rifamycin-induced DNA damage. Free Radic Biol Med 1995;18:747–755.
   PubMed Web of Science ®Google Scholar
• Asensi MD, Sastre J, Pallardó FV, García de la Asunción J, Estrela JM, Viña J. A high-performance liquid chromatography method for measurement of oxidized glutathione in biological samples. Anal Biochem 1994;217:323–328.
   PubMed Web of Science ®Google Scholar
• Wong SHY, Knight JA, Hopfer SM, Zaharia O, Leach CN Jr, Sunderman FW Jr. Lipidperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clin Chem 1987;33:214–220.
   PubMed Web of Science ®Google Scholar
• Frenkel K, Zong Z, Wei H, Karkiszka J, Patel U, Rashid K, Georgescu M, Solomon JJ. Quantitative high performance liquid chromatography analysis of DNA oxidized in vitro and in vivo. Anal Biochem 1991;196:126–136.
   PubMed Web of Science ®Google Scholar
• Gedik CM, Collins A. ESCODD (European standard committee on oxidative DNA damage). Establishing the back ground level of base oxidation in human lymphocyte DNA: results of an inter-laboratory validation study. FASEB J 2005;19:82–84.
   PubMed Web of Science ®Google Scholar
• Ross R. The pathogénesis of atherosclerosis: a perspective for the 1990s. Nature 1993;362:801–809.
   PubMed Web of Science ®Google Scholar
• Arder DJ, Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis. Nature 2008;451:904–913.
   Google Scholar
• Katan MB, Grundy SM, Willett WC. Schould a low-fat, high-carbohydrate diet be recommended for everyone? Beyond low-fat diets. N Engl J Med 1997;337:563–566.
   PubMed Web of Science ®Google Scholar
• Kris-Etherton PM, AHA Science Advisory. Monounsaturated fatty acids and risk of cardiovascular disease. American Heart Association. Nutrit Committee Circulation 1999;100:1253–1258.
   PubMed Web of Science ®Google Scholar
• Chaves FJ, Mansego ML, Blesa S, Gonzalez-Albert V, Jimenez J, Tormos Espinosa O, Giner V, Iradi A, Saez G, Redon J. Inadequate cytoplasmic antioxidant enzymes response contributing to the oxidative stress in human hypertension. Am J Hypertens 2007;20:62–69.
   Google Scholar
• Mansego ML, Blesa S, Gonzalez-Albert V, Tormos MC, Sáez G, Redon J, Chaves FJ. Discordant response of glutathione and thioredoxin systems in human hypertension?. Antioxid Redox Signal 2007;9:507–514.
   Google Scholar
• Ashfaq S, Abramson JL, Jones DP, Rhodes SD, Weintraub WS, Hooper Vaccarino V, Harrison DG, Quyyumi AA. The relationship between plasma levels of oxidized and reduced thiols and early atherosclerosis in healthy adults. J Am Coll Cardiol 2006;47:1005–1011.
   PubMed Web of Science ®Google Scholar
• Andreassi MG, Botto N. DNA damage as a new emerging risk factor in atherosclerosis. Trends Cardiovasc Med 2003;13:270–275.
   PubMed Web of Science ®Google Scholar
• Bennet MS. Reactive oxygen species and death. Oxidative DNA damage in atherosclerosis. Circulation Res 2001;88:648–650.
   Google Scholar
• Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix-degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994;94:2493–2503.
   PubMed Web of Science ®Google Scholar
• Mercer J, Bennett M. The role of p53 in atherosclerosis. Cell Cycle 2006;5:1907–1909.
   PubMed Web of Science ®Google Scholar
• Borras C, Gambine J, Gomez-Cabrera MC, Satre J, Pallardo FV, Mann GE, Viña J. Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: involvement of estrogen receptors ERK1/2 and NFkappaB. FASEB J 2006;20:2136–2138.
   PubMedGoogle Scholar
• Kahn R, Buse J, Ferrannini E, Stern M. American Diabetes Association; European Association for the Study of Diabetes. The metabolic syndrome: time for a critical appraisal: joint statement from the American Association and the European Association for the Study of Diabetes. Diab Care 2005;28:2289–2304.
   PubMed Web of Science ®Google Scholar
• Raij L. Nitric oxide in hypertension: relationship with renal injury and left ventricular hypertrophy. Hypertension 1998;31:189–193.
   PubMed Web of Science ®Google Scholar