Similarities and differences of hyperbaric oxygen and medical ozone applications

References

• Biddle C. Oxygen: The two-faced elixir of life. AANA J 2008;76:61–68.
   PubMedGoogle Scholar
• Williams RJ. A system's view of the evolution of life. J R Soc Interface 2007;4:1049–1070.
   PubMed Web of Science ®Google Scholar
• Maltepe E, Saugstad OD. Oxygen in health and disease: regulation of oxygen homeostasis–clinical implications. Pediatr Res 2009;65:261–268.
   PubMed Web of Science ®Google Scholar
• Rowland FS. Stratospheric ozone depletion. Philos Trans R Soc Lond B Biol Sci 2006;361:769–790.
   PubMed Web of Science ®Google Scholar
• van der Leun JC. The ozone layer. Photodermatol Photoimmunol Photomed 2004;20:159–162.
   PubMed Web of Science ®Google Scholar
• McKenzie RL, Bjorn LO, Bais A, Ilyasad M. Changes in biologically active ultraviolet radiation reaching the Earth’s surface. Photochem Photobiol Sci 2003;2:5–15.
   PubMed Web of Science ®Google Scholar
• Rozema J, Boelen P, Blokker P. Depletion of stratospheric ozone over the antarctic and arctic: responses of plants of polar terrestrial ecosystems to enhanced UV-B, an overview. Environ Pollut 2005;137:428–442.
   PubMed Web of Science ®Google Scholar
• Bjorn LO, McKenzie RL. Attempts to probe the ozone layer and the ultraviolet-B levels of the past. Ambio 2007; 36:366–371.
   PubMed Web of Science ®Google Scholar
• Gill AL, Bell CN. Hyperbaric oxygen: its uses, mechanisms of action and outcomes. QJM 2004;97:385–395.
   PubMed Web of Science ®Google Scholar
• Simpson I. Compressed air as a therapeutic agent in the treatment of consumption, asthma, chronic bronchitis and other diseases. Edinburgh: Sutherland & Knox; 1857.
   Google Scholar
• Fontaine JA. Emplloi chirurgical de l'air comprime. Union Med 1879;28:445.
   Google Scholar
• Kindwall EP, Whelan HT. Hyperbaric Medicine Practice. 2nd ed. Flagstaff, AZ: Best Publishing Company; 2002.
   Google Scholar
• Bert P. La pression barometrique: recherches de physiologie experimentale. 1878. Translated by Hitchcock MA, Hitchcock FA. Published as: Barometric pressure: researches in experimental physiology. Columbus College Book Company; 1943.
   Google Scholar
• Smith JL. The pathological effects due to increase of oxygen tension in the air breathed. J Physiol 1899;24:19–35.
   PubMedGoogle Scholar
• Cross FS. Effects of increased atmospheric pressures and inhalation of 95% oxygen and helium oxygen mixture on the viability of the bowel wall and the absorption of gas in closed loop obstructions. Surgery 1954;36:1001–1026.
   PubMed Web of Science ®Google Scholar
• Fukaya E, Hopf HW. HBO and gas embolism. Neurol Res 2007;29:142–145.
   PubMed Web of Science ®Google Scholar
• Piktin AD, Davies NJH. Hyperbaric oxygen therapy. Br J Anaesth 2001;1:150–156.
   Google Scholar
• Jiang J, Tyssebotn I. Normobaric and hyperbaric oxygen treatment of acute carbon monoxide poisoning in rats. Undersea Hyperb Med 1997;24:107–116.
   PubMed Web of Science ®Google Scholar
• Jiang J, Tyssebotn I. Cerebrospinal fluid pressure changes after acute carbon monoxide poisoning and therapeutic effects of normobaric and hyperbaric oxygen in conscious rats. Undersea Hyperb Med 1997;24:245–254.
   PubMed Web of Science ®Google Scholar
• Weaver LK, Hopkins RO, Chan KJ, Churchill S, Elliott CG, Clemmer TP, . Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med 2002;347:1057–1067.
   PubMed Web of Science ®Google Scholar
• Murata M, Suzuki M, Hasegawa Y, Nohara S, Kurachi M. Improvement of occipital alpha activity by repetitive hyperbaric oxygen therapy in patients with carbon monoxide poisoning: a possible indicator for treatment efficacy. J Neurol Sci 2005;235:69–74.
   PubMed Web of Science ®Google Scholar
• Boussuges A, Blanc P, Molenat F, Bergmann E, Sainty JM. Prognosis in iatrogenic gas embolism. Minerva Medica 1995;86:453–457.
   PubMedGoogle Scholar
• Thom SR, Fisher D, Xu YA, Garner S, Ischiropoulos H. Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat. Am J Physiol 1999;276:984–992.
   PubMed Web of Science ®Google Scholar
• Brown SD, Piantadosi CA. Recovery of energy metabolism in rat brain after carbon monoxide hypoxia. J Clin Invest 1991;89:666–672.
   Web of Science ®Google Scholar
• Stevens DL, Bryant AE, Adams K, Mader JT. Evaluation of therapy with hyperbaric oxygen for experimental infection with Clostridium perfringens. Clin Infect Dis 1993;17: 231–237.
   PubMed Web of Science ®Google Scholar
• Bouachour G, Cronier P, Gouello JP, Toulemonde JL, Talha A, Alquier P. Hyperbaric oxygen therapy in the management of crush injuries: A randomized double-blind placebo-controlled clinical trial. J Trauma 1996;41:333–339.
   PubMedGoogle Scholar
• Stone JA, Cianci P. The adjunctive role of hyperbaric oxygen therapy in the treatment of lower extremity wounds in patients with diabetes. Diabetes Spectrum 1997;10:118–123.
   Google Scholar
• Hart G. HBO and exceptional blood loss anemia. In: Kindwall EP, Whalen HT, eds. Hyperbaric Medicine Practice. Flagstaff, AZ: Best Publishing Company; 1999:741–751.
   Google Scholar
• Lampl L, Frey G, Bock KH. Hyperbaric oxygen in intracranial abscesses - update of a series of 13 patients. Undersea Biomed Res 1992;19:83.
   Google Scholar
• Rubin MB. The history of ozone. Bull Hist Chem 2001;26: 40–56.
   Google Scholar
• Bocci V. Scientific and medical aspects of ozone therapy. State of the art. Arch Med Res 2006;37:425–435.
   PubMed Web of Science ®Google Scholar
• Bocci V. Oxygen-ozone therapy: a critical evaluation. Dordrecht, Nederland: Kluwer Academic Publishers; 2002. pp. 1–37.
   Google Scholar
• Wright ES, Dziedzic D, Wheeler CS. Cellular, biochemical and functional effects of ozone: new research and perspectives on ozone health effects. Toxicol Lett 1990;51:125–145.
   PubMed Web of Science ®Google Scholar
• Sanhueza PA, Reed GD, Davis WT, Miller TL. An environmental decision-making tool for evaluating ground-level ozone-related health effects. J Air Waste Manag Assoc 2003;53:1448–1459.
   PubMedGoogle Scholar
• Di Paolo N, Bocci V, Gaggiotti E. Ozone therapy. Int J Artif Organs 2004;27:168–175.
   PubMed Web of Science ®Google Scholar
• Wolff HH. Die Behandlung peripherer Durchblutungsstorungen mit Ozon. Erfahr-Heilkd 1974;23:181–184.
   Google Scholar
• Bocci V, Aldinucci C. Biochemical modifications induced in human blood by oxygenation-ozonation. J Biochem Mol Toxicol 2006;20:133–138.
   PubMed Web of Science ®Google Scholar
• Bocci V, Borrelli E, Travagli V, Zanardi I. The ozone paradox: ozone is a strong oxidant as well as a medical drug. Med Res Rev. 2009;29:646–682.
   PubMed Web of Science ®Google Scholar
• Travagli V, Zanardi I, Silvietti A, Bocci V. A physicochemical investigation on the effects of ozone on blood. Int J Biol Macromol 2007;41:504–511.
   PubMed Web of Science ®Google Scholar
• Di Paolo N, Gaggiotti E, Galli F. Extracorporeal blood oxygenation and ozonation: clinical and biological implications of ozone therapy. Redox Rep 2005;10:121–130.
   PubMed Web of Science ®Google Scholar
• Pryor WA, Squadrito GL, Friedman M. A new mechanism for the toxicity of ozone. Toxicol Lett 1995;82:287–293.
   PubMed Web of Science ®Google Scholar
• Pryor WA, Squadrito GL, Friedman M. The cascade mechanism to explain ozone toxicity: the role of lipid ozonation products. Free Radic Biol Med 1995;19:935–941
   PubMed Web of Science ®Google Scholar
• Mustafa MG. Biochemical basis of ozone toxicity. Free Radic Biol Med 1990;9:245–265.
   PubMed Web of Science ®Google Scholar
• Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81–128.
   PubMed Web of Science ®Google Scholar
• Hamilton RF, Eschenbacher WL, Szweda L, Holian A. Potential involvement of 4-hydroxynonenal in the response of human lung cells to ozone. Am J Physiol 1998;274: L8–L16.
   Google Scholar
• Schaur RJ. Basic aspects of the biochemical reactivity of 4-hydroxynonenal. Mol Aspects Med 2003;24:149–159.
   PubMedGoogle Scholar
• Bocci V. Ozone as Janus: this controversial gas can be either toxic or medically useful. Mediators Inflamm 2004;13:3–11.
   PubMed Web of Science ®Google Scholar
• Valacchi G, Bocci V. Studies on the biological effects of ozone: 11. Release of factors from human endothelial cells. Mediators Inflamm 2000;9:271–276.
   PubMed Web of Science ®Google Scholar
• Bocci V. Ozone: a new medical drug. Dordrecht, Netherlands: Springer; 2005:19–24.
   Google Scholar
• Viebahn-Hänsler R. The use of ozone in medicine. 5th ed. Iffezheim, Germany: Odrei Publishers; 2007.
   Google Scholar
• Bocci V, Luzzi E, Corradeschi F, Paulesu L. Studies on the biological effects of ozone: 5. Evaluation of immunological parameters and tolerability in normal volunteers receiving ambulatory autohaemotherapy. Biotherapy 1993;7:83–90.
   PubMedGoogle Scholar
• Bocci V, Paulesu L. Studies on the biological effects of ozone 1. Induction of interferon gamma on human leucocytes. Haematologica 1990;75:510–515.
   PubMed Web of Science ®Google Scholar
• Bocci V, Luzzi E, Corradeschi F, Silvestri S. Studies on the biological effects of ozone: 6. Production of transforming growth factor 1 by human blood after ozone treatment. J Biol Regul Homeost Agents 1994;8:108–112.
   PubMed Web of Science ®Google Scholar
• Larini A, Bocci V. Effects of ozone on isolated peripheral blood mononuclear cells. Toxicol In Vitro 2005;19:55–61.
   PubMed Web of Science ®Google Scholar
• Stubinger S, Sader R, Filippi A. The use of ozone in dentistry and maxillofacial surgery: a review. Quintessence Int 2006; 37:353–359.
   PubMed Web of Science ®Google Scholar
• Bocci V, Zanardi I, Travagli V. Has oxygen-ozonetherapy a future in medicine?. J Exp Integr Med 2011;1:5–11.
   Google Scholar
• Bocci V. The case for oxygen-ozonetherapy. Br J Biomed Sci 2007;64:44–49.
   PubMed Web of Science ®Google Scholar
• Yasar M, Yildiz S, Mas R, Dundar K, Yildirim A, Korkmaz A, . The effect of hyperbaric oxygen treatment on oxidative stress in experimental acute necrotizing pancreatitis. Physiol Res 2003;52:111–116.
   PubMed Web of Science ®Google Scholar
• Oter S, Edremitlioglu M, Korkmaz A, Coskun O, Kilic D, Kisa U, . Effects of hyperbaric oxygen treatment on liver functions, oxidative status and histology in septic rats. Intensive Care Med 2005;31:1262–1268.
   PubMed Web of Science ®Google Scholar
• Yilmaz MI, Korkmaz A, Kaya A, Sonmez A, Çaglar K, Topal T, . Hyperbaric oxygen treatment augments the efficacy of a losartan regime in an experimental nephrotic syndrome model. Nephron Exp Nephrol 2006;104:15–22.
   PubMedGoogle Scholar
• Gulec B, Yasar M, Yildiz S, Oter S, Akay C, Deveci S, Sen D. Effect of hyperbaric oxygen on experimental acute distal colitis. Physiol Res 2004;53:493–499.
   PubMed Web of Science ®Google Scholar
• Gordillo GM, Sen CK. Revisiting the essential role of oxygen in wound healing. The Am J Surg 2003;186:259–263
   PubMed Web of Science ®Google Scholar
• Sen CK. Wound healing essentials: let there be oxygen. Wound Repair Regen 2009;17:1–18.
   PubMed Web of Science ®Google Scholar
• Tandara AA, Mustoe TA. Oxygen in wound healing–more than a nutrient. World J Surg 2004;28:294–300.
   PubMed Web of Science ®Google Scholar
• Bocci V. Biological and clinical effects of ozone. Has ozone therapy a future in medicine? Br J Biomed Sci 1999; 56:270–279.
   PubMed Web of Science ®Google Scholar
• Valacchi G, Bocci V. Studies on the biological effects of ozone: 10. Release of factors from ozonated human platelets. Mediators Inflamm 1999;8:205–209.
   PubMed Web of Science ®Google Scholar
• Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM. Therapeutic effects of topical application of ozone on acute cutaneous wound healing. J Korean Med Sci 2009;24:368–374.
   PubMed Web of Science ®Google Scholar
• Kang TS, Gorti GK, Quan SY, Ho M, Koch RJ. Effect of hyperbaric oxygen on the growth factor profile of fibroblasts. Arch Facial Plast Surg 2004;6:31–35.
   PubMedGoogle Scholar
• Uysal B, Yasar M, Ersoz N, Coskun O, Kilic A, Cayc T, . Efficacy of hyperbaric oxygen therapy and medical ozone therapy in experimental acute necrotizing pancreatitis. Pancreas 2010;39:9–15.
   PubMed Web of Science ®Google Scholar
• Altinel O, Demirbas S, Cakir E, Yaman H, Ozerhan IH, Duran E, . Comparison of hyperbaric oxygen and medical ozone therapies in a rat model of experimental distal colitis. Scand J Clin Lab Invest 2011;71:185–192.
   PubMed Web of Science ®Google Scholar
• Bocci V. Ozone: a new medical drug. Dordrecht, Netherlands: Springer; 2005:227–230.
   Google Scholar
• Gesell LB, ed. Hyperbaric oxygen therapy indications. The hyperbaric oxygen therapy committee report. 12th ed. Durham, NC: Undersea and Hyperbaric Medical Society; 2008.
   Google Scholar
• Monstrey ST, Mullick P, Narayanan K, Ramasastry SS. Hyperbaric oxygen therapy and free radical production: an experimental study in doxorubicin (adriamycin) extravasation injuries. Ann Plast Surg 1997;38:163–168.
   PubMed Web of Science ®Google Scholar
• Simsek K, Ozler M, Ucar E, Sadir S, Demirbas S, Uysal B, Ay H. Pressure-related effects of hyperbaric oxygen exposure on oxidation products and antioxidant enzymes in the rat lung. J Exp Integr Med 2011;1:37–42.
   Google Scholar
• Alleva R, Nasole E, Di Donato F, Borghi B, Neuzil J, Tomasetti M. α-Lipoic acid supplementation inhibits oxidative damage, accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy. Biochem Biophys Res Commun 2005;333:404–410.
   PubMed Web of Science ®Google Scholar
• Muth CM, Glenz Y, Klaus M, Radermacher P, Speit G, Leverve X. Influence of an orally effective SOD on hyperbaric oxygen related cell damage. Free Rad Res 2004;38:927–932.
   PubMed Web of Science ®Google Scholar
• Mollaoglu H, Topal T, Ozler M, Uysal B, Reiter RJ, Korkmaz A, Oter S. Antioxidant effects of melatonin in rats during chronic exposure to hyperbaric oxygen. J Pineal Res 2007; 42:5054.
   Web of Science ®Google Scholar
• Gloria L. Hyperbaric Oxygen Therapy: Pre-and post treatment nursing responsibilities every staff nurse needs to know about. Am J Nursing 2001;101:26–34.
   Google Scholar
• Bocci V. Ozone: a new medical drug. Dordrecht, Netherlands: Springer; 2005:75–85.
   Google Scholar
• Ozler M, Oter S, Korkmaz A. The use of ozone gas for medical purposes. TAF Prev Med Bull 2009;8:69–74.
   Google Scholar
• Jamieson, DD, Lipid peroxidation in brain and lungs from mice exposed to hyperoxia. Biochem Pharmacol 1991;41: 749–756.
   PubMed Web of Science ®Google Scholar
• Harabin AL, Braisted JC, Flynn ET, Response of antioxidant enzymes to intermittent and continuous hyperbaric oxygen, J Appl Physiol 1990;69:328–335.
   PubMed Web of Science ®Google Scholar
• Farber JL, Kyle ME, Coleman JB. Mechanism of cell injury by activated oxygen species. Lab Invest 1990;62: 670–679.
   PubMed Web of Science ®Google Scholar
• Oriani G, Michael M., Marroni A, Longoni C. Physiology and physiopathology of hyperbaric oxygen. In Oriani G, Marroni A, Wattel F, eds. Handbook on Hyperbaric Medicine. Berlin, Germany: Springer; 1996. pp. 18–34.
   Google Scholar
• Richter C. Reactive Oxygen and DNA Damage in Mitochondria. Mutat Res 1992;275:249–255.
   PubMed Web of Science ®Google Scholar
• Jain KK. Hyperbaric oxygen therapy in wound healing. In: Jain KK, ed. Textbook of Hyperbaric Medicine. Hogrefe & Huber Publishers; 1990. pp. 193–202.
   Google Scholar
• Oter S, Topal T, Sadir S, Ozler M, Uysal B, Ay H, . Oxidative stress levels in rats following exposure to oxygen at 3 atm for 0–120 min, Aviat Space Environ Med 2007;78:1108–1113.
   PubMedGoogle Scholar
• Korkmaz A, Oter S, Sadir S, Topal T, Uysal B, Ozler M, . Exposure time related oxidative action of hyperbaric oxygen in rat brain, Neurochem Res 2008;33:160–166.
   PubMed Web of Science ®Google Scholar
• Dundar K, Topal T, Ay H, Oter S, Korkmaz A. Protective effects of exogenously administered or endogenously produced melatonin on hyperbaric oxygen-induced oxidative stress in the rat brain. Clin Exp Pharmacol Physiol 2005; 32:926–930.
   PubMed Web of Science ®Google Scholar
• Bocci V. Is it true that ozone is always toxic? The end of a dogma. Toxicol Appl Pharmacol 2006;216:493–504
   PubMed Web of Science ®Google Scholar
• Korkmaz A, Oter S, Sadir S, Coskun O, Topal T, Ozler M, Bilgic H. Peroxynitrite may be involved in bladder damage caused by cyclophosphamide in rats. J Urol 2005;173:1793–1796.
   PubMed Web of Science ®Google Scholar
• Jannsen YMW, Van Houten B, Borm PJA, Mossman BT. Cell and tissue response to oxidative damage. Lab Invest 1993; 69:261–274.
   PubMed Web of Science ®Google Scholar
• Wiseman H, Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J 1996;313:17–29.
   PubMed Web of Science ®Google Scholar
• Young IS, Woodside JV. Antioxidants in health and disease. J Clin Pathol 2001;54:176–186
   PubMed Web of Science ®Google Scholar
• Korkmaz A, Akay C. Toward to understanding the role of reactive molecules in bio-oxidative treatment modalities. J Exp Integr Med 2011;1:3–4.
   Google Scholar
• Powis G, Briehl M, Oblong J. Redox signaling and the control of cell growth and death. Pharmacol Ther 1995;65: 149–173.
   PubMedGoogle Scholar
• Lander HM. An essential role for free radicals and derived species in signal transduction. FASEB J 1997;11:118–124.
   PubMed Web of Science ®Google Scholar
• Thannickal VJ, Fanburg BL Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 2000;279: L1005–L1028.
   PubMed Web of Science ®Google Scholar
• Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007; 39:44–84.
   PubMed Web of Science ®Google Scholar
• Hink J, Jansen E. Are superoxide and/or hydrogen peroxide responsible for some of the beneficial effects of hyperbaric oxygen therapy? Med Hypotheses 2001;57:764–769.
   PubMed Web of Science ®Google Scholar
• Thom SR. Oxidative stress is fundamental to hyperbaric oxygen therapy. J Appl Physiol 2009;106:988–995.
   PubMed Web of Science ®Google Scholar
• Oter S, Korkmaz A. Relevance of hyperbaric oxygen to ozone therapy. Arch Med Res 2006;37:917–918.
   PubMed Web of Science ®Google Scholar
• Larini A, , Bianchi lBocci V. The Ozone tolerance: i) enhancement of antioxidant enzymes is ozone dose-dependent in jurkat cells. Free Radic Res 2003;37:1163–1168.
   PubMed Web of Science ®Google Scholar
• Hernández F, Menéndez S, Wong R. Decrease of blood cholesterol and stimulation of antioxidative response in cardiopathy patients treated with endovenous ozone therapy. Free Radic Biol Med 1995;19:115–119.
   PubMed Web of Science ®Google Scholar
• Martínez-Sánchez G, Al-Dalain SM, Menéndez S, Re L, Giuliani A, Candelario-Jalil E, Alvarez H, . Therapeutic efficacy of ozone in patients with diabetic foot. Eur J Pharmacol 2005;523:151–161.
   PubMed Web of Science ®Google Scholar
• Chen H, Xing B, Liu X, Zhan B, Zhou J, Zhu H, Chen Z. Ozone oxidative preconditioning protects the rat kidney from reperfusion injury: the role of nitric oxide. J Surg Res 2008;149:287–295.
   PubMed Web of Science ®Google Scholar
• Ajamieh HH, Menéndez S, Martínez-Sánchez G, Candelario-Jalil E, Re L, Giuliani A, Fernández OS. Effects of ozone oxidative preconditioning on nitric oxide generation and cellular redox balance in a rat model of hepatic ischaemia-reperfusion. Liver Int 2004;24:55–62.
   PubMed Web of Science ®Google Scholar
• Dennog C, Hartmann A, Frey G, Speit G. Detection of DNA damage after hyperbaric oxygen (HBO) therapy. Mutagenesis 1996;11:605–609.
   PubMed Web of Science ®Google Scholar
• Speit G, Dennog C, Lampl L. Biological significance of DNA damage induced by hyperbaric oxygen, Mutagenesis 1998;13:85–87.
   PubMed Web of Science ®Google Scholar
• Rothfuss A, Dennog C, Speit G. Adaptive protection against the induction of oxidative DNA damage after hyperbaric oxygen treatment. Carcinogenesis 1998;19:1913–1917.
   PubMed Web of Science ®Google Scholar
• Speit G, Dennog C, Radermacher P, Rothfuss A. Genotoxicity of hyperbaric oxygen, Mutat Res 2002;512:111–119.
   PubMed Web of Science ®Google Scholar
• Rothfuss A, Speit G. Investigations on the mechanism of hyperbaric oxygen (HBO)-induced adaptive protection against oxidative stress. Mutat Res 2002;508:157–165.
   PubMed Web of Science ®Google Scholar
• Fritz HB. Heme oxygenase-1: a therapeutic amplification funnel. FASEB J 2005;19:1216–1219.
   PubMed Web of Science ®Google Scholar
• Verma A, Hirsch DJ, Glatt CE, Ronnett GV, Snyder SH. Carbon monoxide: a putative neural messenger. Science 1993;259:381–384.
   PubMed Web of Science ®Google Scholar
• Otterbein LE, Mantell LL, Choi AM. Carbon monoxide provides protection against hyperoxic lung injury. Am J Physiol 1999;276:L688–L694.
   PubMed Web of Science ®Google Scholar
• Ryter SW, Choi AM. Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy. Am J Respir Cell Mol Biol 2009;41:251–260.
   PubMed Web of Science ®Google Scholar
• Zeng B, Chen H, Zhu C, Ren X, Lin G, Cao F. Effects of combined mesenchymal stem cells and heme oxygenase-1 therapy on cardiac performance. Eur J Cardiothorac Surg 2008;34:850–856.
   PubMed Web of Science ®Google Scholar
• Seixas E, Gozzelino R, Chora A, Ferreira A, Silva G, Larsen R, . Heme oxygenase-1 affords protection against noncerebral forms of severe malaria. Proc Natl Acad Sci USA 2009;106:15837–41582.
   PubMed Web of Science ®Google Scholar
• Bocci V, Aldinucci C, Mosci F, Carraro F, Valacchi G. Ozonation of human blood induces a remarkable upregulation of heme oxygenase-1 and heat stress protein-70. Mediators Inflamm 2007;2007:26785.
   PubMed Web of Science ®Google Scholar
• Speit G, Dennog C, Eichhorn U, Rothfuss A, Kaina B. Induction of heme oxygenase-1 and adaptive protection against the induction of DNA damage after hyperbaric oxygen treatment. Carcinogenesis 2000;21: 1795–1799.
   PubMed Web of Science ®Google Scholar
• Rothfuss A, Radermacher P, Speit G. Involvement of heme oxygenase-1 (HO-1) in the adaptive protection of human lymphocytes after hyperbaric oxygen (HBO) treatment. Carcinogenesis 2001;22:1979–1985.
   PubMed Web of Science ®Google Scholar