References
- Demedts IK, Demoor T, Bracke KR, Joos GF, Brusselle GG. Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res 2006;7:53–62.
- Chandra J, Samali A, Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 2000;29:323–333.
- Malia P, Johnson SL. How viral infections causes exacerbations of airway diseases. Chest 2006;130:1203–1210.
- Kirkham P, Rahman I. Oxidative stress in asthma and COPD: antioxidants as a therapeutic strategy. Pharmacol Ther 2006;111:476–494.
- Rahman MS, Yang J, Shan LY, Unruh H, Yang X, Halayko AJ, . IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional-dependent mechanism. Clin Immunol 2005;115:268–276.
- Biswas SK, Rahman I. Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Mol Aspects Med 2009;30:60–76.
- Morton S, Davis RJ, McLaren A, Cohen P. A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun. EMBO J 2003;22:3876–3886.
- Alani R, Brown P, Binétruy B, Dosaka H, Rosenberg RK, Angel P, . The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells. Mol Cell Biol 1991;11:6286–6295.
- Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000;351:95–105.
- Pulverer BJ, Kyriakis JM, Avruch J, Nikolakaki E, Woodgett JR. Phosphorylation of c-jun mediated by MAP kinases. Nature 1991;353:670–674.
- Hsieh HL, Wang HH, Wu WB, Chu PJ, Yang CM. Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways. J Neuroinflamm 2010;7: 88–104.
- Hatzelmann A, Morcillo EJ, Lungarella G, Adnot S, Sanjar S, Beume R, . The preclinical pharmacology of roflumilast—a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease. Pulm Pharmacol Ther 2010;23:235–256.
- Kwak HJ, Song JS, Heo JY, Yang SD, Nam JY, Cheon HG, . Roflumilast inhibits lipopolysaccharide-induced inflammatory mediators via suppression of nuclear factor-κB, p38 mitogen-activated protein kinase, and c-Jun NH2-terminal kinase activation. J Pharmacol Exp Ther 2005;315: 1188–1195.
- Zhao CZ, Fang XC, Wang D, Tang FD, Wang XD. Involvement of type II pneumocytes in the pathogenesis of chronic obstructive pulmonary disease. Respir Med 2010;104: 1391–1395.
- Mata M, Sarriá B, Buenestado A, Cortijo J, Cerdá M, Morcillo EJ, . Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells. Thorax 2005;60:144–152.
- Li C, Wong WH. Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biol 2001;2:research 0032. 1–0032.11.
- Barco A, Patterson S, Alarcon JM, Gromova P, Mata-Roig M, Morozov A, . Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture. Neuron 2005;8:123–137.
- Messeguer X, Escudero R, Farré D, Nuñez O, Martínez J, Albà MM, . PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics 2002;18:333–334.
- Farré D, Roset R, Huerta M, Adsuara JE, Roselló L, Albà MM, . Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN. Nucleic Acids Res 2003;31:3651–3653.
- Martinez-Losa M, Cortijo J, Piqueras L, Sanz MJ, Morcillo EJ. Taurine chloramine inhibits functional responses of human eosinophils in vitro. Clin Exp Allergy 2009;39: 537–546.
- Toby GG, Gherraby W, Coleman TR, Golemis EA. A novel RING finger protein, human enhancer of invasion 10, alters mitotic progression through regulation of cyclin B levels. Mol Cell Biol 2003;23:2109–2122.
- Contour-Galcera MO, Sidhu A, Prévost G, Bigg D, Ducommun B. What's new on CDC25 phosphatase inhibitors. Pharmacol Ther 2007;115:1–12.
- Yeh CT, Lu SC, Chao CH, Chao ML. Abolishment of the interaction between cyclin-dependent kinase 2 and Cdk-associated protein phosphatase by a truncated KAP mutant. Biochem Biophys Res Commun 2003;305:311–314.
- Demedts IK, Demoor T, Bracke KR, Joos GF, Brusselle GG. Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema. Respir Res 2007;30:7–53.
- De Paepe ME, Gundavarapu S, Tantravahi U, Pepperell JR, Haley SA, Luks FI, . Fas-ligand-induced apoptosis of respiratory epithelial cells causes disruption of postcanalicular alveolar development. Am J Pathol 2008;173: 42–56.
- Norambuena A, Metz C, Vicuña L, Silva A, Pardo E, Oyanadel C, . Galectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation. J Biol Chem 2009;284:12670–12679.
- Marfe G, Pucci B, De Martino L, Fiorito F, Di Stefano C, Indelicato M, . Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. Int J Cancer 2009;125:2077–2085.
- Humphrey RK, Newcomb CJ, Yu SM, Hao E, Yu D, Krajewski S, . Mixed lineage kinase-3 stabilises and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. J Biol Chem 2010;285:22426–22436.
- Buford TW, Cooke MB, Willoughby DS. Resistance exercise induced changes of inflammatory gene expression within human skeletal muscle. Eur J Appl Physiol 2009;107: 463–471.
- Chaum E, Yin J, Yang H, Thomas F, Lang JC. Quantitative AP-1 gene regulation by oxidative stress in the human retinal pigment epithelium. J Cell Biochem 2009;108: 1280–1291.
- Schmeck B, Gross R, N'Guessan PD, Hocke AC, Hammerschmidt S, Mitchell TJ, . Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium. Infect Immun 2006;72:4940–4947.
- Chen LW, Chang WJ, Wang JS, Hsu CM. Interleukin-1 mediates thermal injury-induced lung damage through C-Jun NH2-terminal kinase signaling. Crit Care Med 2007;35:1113–1122.
- Rahman I, Gilmour PS, Jimenez LA, MacNee W. Oxidative stress and TNF-α induce histone acetylation and NF-κB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. Mol Cell Biochem 2002;234–235:239–248.
- Markova TP, Niwa A, Yamanishi H, Aragane Y, Higashino H. Antagonism of IL-4 signaling by a phosphodiesterase-4 inhibitor, rolipram, in human T cells. Int Arch Allergy Immunol 2007;143:216–224.
- Brown DM, Hutchison L, Donaldson K, MacKenzie SJ, Dick CA, Stone V, . The effect of oxidative stress on macrophages and lung epithelial cells: the role of phosphodiesterases 1 and 4. Toxicol Lett 2007;168:1–6.