455
Views
137
CrossRef citations to date
0
Altmetric
Original Article

Mechanism of Copper-Catalyzed Oxidation of Glutathione

, &
Pages 259-269 | Received 28 Aug 1997, Published online: 07 Jul 2009

References

  • Misra H. P. Generation of superoxide free radical during the autoxidation of thiols. Journal of Biological Chemistry 1974; 249: 2151–2155
  • Albro P. W., Corbett J. T., Schroeder J. L. Generation of hydrogen peroxide by incidental metal ion-catalyzed autooxidation of glutathione. Journal of Inorganic Biochemistry 1986; 27: 191–203
  • Biaglow J. E., Issels R. W., Gerweck L. E., Varnes M. E., Jacobson B., Mitchell J. B., Russo A. Factors influencing the oxidation of cysteamine and other thiols: implications for hyperthermic sensitization and radiation protection. Radiation Research 1984; 100: 298–312
  • Winterbourn C. C., Metodiewa D. The reaction of superoxide with reduced glutathione. Archives of Biochemistry and Biophysics 1994; 314: 284–290
  • Reed C. J., Douglas K. T. Chemical cleavage of plasmid DNA by glutathione in the presence of Cu(II) ions. The Cu(II)-thiol system for DNA strand scission. Biochemical Journal 1991; 275: 601–608
  • Heinecke J. W., Kawamura M., Suzuki L., Chait A. Oxidation of low density lipoprotein by thiols: superoxide-dependent and -independent mechanism. Journal of Lipid Research 1993; 34: 2051–2061
  • Hanna P. M., Mason R. P. Direct evidence for inhibition of free radical formation from Cu(I) and hydrogen peroxide by glutathione and other potential ligands using the EPR spin-trapping technique. Archives of Biochemistry and Biophysics 1992; 295: 205–213
  • Freedman J. H., Peisach J. Intracellular copper transport in cultured hepatoma cells. Biochemical & Biophysical Research Communications 1989; 164: 134–140
  • Ferreira A. M., Ciriolo M. R., Marcocci L., Rotilio G. Copper (I) transfer into metallothionein mediated by glutathione. Biochemical Journal 1993; 292: 673–676
  • Pederson J. Z., Steinkuhler C., Weser U., Rotilio G. Copper-glutathione complexes under physiological conditions: structures in solution different from the solid state coordination. Biometals 1996; 9: 3–9
  • Jouini M., Lapluye G., Huet J., Julien R., Ferradini C. Catalytic activity of a copper(II)-oxidized glutathione complex on aqueous superoxide ion dismu-tation. Journal of Inorganic Biochemistry 1986; 26: 269–280
  • Milne L., Nicotera P., Orrenius S., Burkitt M. J. Effect of glutathione and chelating agents on copper-mediated DNA oxidation: pro-oxidant and antioxidant properties of glutathione. Archives of Biochemistry and Biophysics 1993; 304: 102–109
  • Collins A. K., Makrigiorgos G. M., Svensson G. K. Coumarin chemical dosimeter for radiation therapy. Medical Physics 1994; 21: 1741–1747
  • Kachur A. V., Held K. D., Koch C. J., Biaglow J. E. Mechanism of hydroxyl radicals production in the copper-catalyzed oxidation of dithiothreitol. Radiation Research 1997; 147: 409–415
  • Cavallini D., De Marco C., Dupre S., Rotilio G. The copper catalyzed oxidation of cysteine to cystine. Archives of Biochemistry and Biophysics 1969; 130: 354–361
  • Zhang N., Schuchmann H.-P., von Sonntag C. The reaction of superoxide radical anion with dithiothreitol: a chain process. Journal of Physical Chemistry 1991; 95: 4718–4722
  • Sjoberg L., Eriksen T. E., Revesz L. The reaction of the hydroxyl radical with glutathione in neutral and alkaline aqueous solution. Radiation Research 1982; 89: 255–263
  • Buettner G. R. The pecking order of free radicals and antioxidants: lipid peroxidation, α-tocopherol and ascorbate. Archives of Biochemistry and Biophysics 1993; 300: 535–543
  • Mason R. P., Hanna P. M., Burkitt M. J., Kadiiska M. B. Detection of oxygen-derived radicals in biological systems using electron spin resonance. Enviromental Health Perspectives 1994; 102: 33–36
  • Kachur A. V., Manevich Y., Biaglow J. E. Effect of purine nucleoside phosphates on OH-radical generation by ferrous oxidation. Free Radical Research 1997; 26: 399–408
  • Biaglow J. E., Kachur A. V. The generation of hydroxyl radicals in the reaction of molecular oxygen with polyphosphate complexes of ferrous ion. Radiation Research 7997; 148: 181–187
  • Kachur A. V., Tuttle S. W., Biaglow J. E. Hydroxyl radical can be generated during the autoxidation of iron complexes. 1997, (submitted to Radiation Research).
  • Held K. D., Tuttle S. W., Biaglow J. E. Role of pentose cycle in oxygen radical-mediated toxicity of the thiol-containing radioprotector dithiothreitol in mammalian cells. Radiation Research 1993; 134: 383–389
  • Brunet J., Boily M. J., Cordeau S., des Rosiers C. Effect of N-acetylcysteine in the rat heart reperfused after low-flow ischemia: evidence for a direct scavenging of hydroxyl radical and nitric oxide-dependent increase in coronary flow. Free Radical Biology and Medicine 1995; 19: 627–638
  • Ciriolo M. R., Palamara A. T., Incerpi S., Lafavia E., Bue M. C., de Vito P., Garaci E., Rotilio G. Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection. Journal of Biological Chemistry 1997; 272: 2700–2708
  • Stark A. A., Glass G. A. Role of copper and ceruloplasmin in oxidative mutagenesis induced by the glutathione-gamma-glutamyl transpeptidase system and by other thiols. Environmental & Molecular Mutagenesis 1997; 29: 63–72

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.