1,087
Views
23
CrossRef citations to date
0
Altmetric
Research Article

Effects of bile salts on the lovastatin pharmacokinetics following oral administration to rats

, , , , &
Pages 79-83 | Received 05 May 2010, Accepted 27 Jul 2010, Published online: 01 Sep 2010

References

  • Chun, I.K. (2009). Dissolution and duodenal permeation characteristics of lovastatin from bile salt solid dispersions: role of critical micelle concentration. J Kor Pharm Sci. 39:97–106.
  • Coello, A., Meijide, F., Nunez, E.R., Tato, J.V. (1996). Aggregation behavior of bile salts in aqueous solution. J Pharm Sci. 85:9–15.
  • Dudeja, P.K., Anderson, K.M., Harris, J.S., Buckingham, L., Coon, J.S. (1995). Reversal of multidrug resistance phenotype by surfactants: relationship to membrane lipid fluidity. Arch Biochem Biophys. 319:309–15.
  • Endo, A. (1981). Biological and pharmacological activity of inhibitors pf 3-hydroxy-3-methylglutaryl coenzyme A reductase. Trends Biochem. Sci. 6:10–13.
  • Garnett, W.R. (1995). Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitors. Am J Health Syst Pharm. 52:1639–45.
  • Kakemi, K., Sezaki, H., Konishi, R., Kimura, T., Murakami, M. (1970). Effect of bile salts on the gastrointestinal absorption of drugs. I. Chem Pharm Bull. 18:275–80.
  • Kamas, H.T., Shiu, G., Shah, V.P. (1991). Validation of bioanalytical methods. Pharm Res. 8:421–6.
  • Lacy, C.F., Amstrong, L.L., Goldman, M.P., Lance, L.L. (2009). Drug information handbook. Hudson, USA: Lexi-comp.
  • Lo, Y.L., Huang, J.D. (2000). Effects of sodium deoxycholate and sodium caprate on the transport of epirubicin in human intestinal epithelial Caco-2 cell layers and everted gut sacs of rats. Biochem Pharmacol. 59:665–72.
  • Pan, H.Y., DeVault, A.R., Wang-Iverson, D., Ivashkiv, E., Swanson, B.N., Sugerman, A.A. (1990). Comparative pharmacokinetics and pharmacodynamics of pravastatin and lovastatin. J Clin Pharmacol. 30:1128–35.
  • Pasha, M.K., Muzeeb, S., Basha, S.J.S.B., Shashikumar, D., Mullangi, R., Srinivas, N.R. (2006). Analysis of five HMG-CoA reductase inhibitors-atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies. Biomed Chromatogr. 20:282–93.
  • Poelma, F.G.J., Breäs, R., Tukker, J.J. (1990). Intestinal absorption of drugs. III. The influence of taurocholate on the disappearance kinetics of hydrophilic and lipophilic drugs from the small intestine of the rat. Pharm Res. 7:392–7.
  • Reis, S., Moutinho, C.G., Matos, C., de Castro, B., Gameiro, P., Lima, J.L.F.C. (2004). Noninvasive methods to determine the critical micelle concentration of some bile acid salts. Anal Biochem. 334:117–26.
  • Sasaki, M., Imai, T., Ohtake, H., Azuma, H., Otagiri, M. (1997). Effects of absorption enhancers on the transport of model compounds in Caco-2 cell monolayers: assessment by confocal laser scanning microscopy. J Pharm Sci. 86:779–85.
  • Schachter, M. (2004). Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundam Clin Pharmacol. 19:117–25.
  • Shimazaki, T., Tomita, M., Sadahiro, S., Hayashi, M., Awazu, S. (1998). Absorption-enhancing effects of sodium caprate and palmitoyl carnitine in rat and human colons. Dig Dis Sci. 43:641–5.
  • Sirtori, C.R. (1990). Pharmacology and mechanism of action of the new HMG-CoA reductase inhibitors. Pharm Res. 22:555–63.
  • Subuddhi, U., Mishra, A.K. (2007). Micellization of bile salts in aqueous medium: a fluorescence study. Colloids Surf B Biointerfaces. 57:102–7.
  • Sugioka, H., Moroi, Y. (1998). Micelle formation of sodium cholate and solubilization into the micelle. Biochim Biophys Acta. 1394:99–110.
  • Tobert, J.A. (2003). Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors. Nat Rev Drug Discov. 2:517–26.
  • Yamaguchi, T., Ikeda, C., Sekine, Y. (1986). Intestinal absorption of a beta-adrenergic blocking agents nadolol. II. Mechanism of the inhibitory effect on the intestinal absorption of nadolol by sodium cholate in rats. Chem Pharm Bull. 34:3836–43.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.