Chemoprevention of skin cancer using low HLB surfactant nanoemulsion of 5-fluorouracil: a preliminary study

References

• Ahmed M, Ramadan W, Rambhu D, Shakeel F. (2008). Potential of nanoemulsions for intravenous delivery of rifampicin. Pharmazie 63:806–11
   PubMed Web of Science ®Google Scholar
• Alvi IA, Madan J, Kaushik D, et al. (2011). Comparative study of transferosomes, liposomes, and niosomes for topical delivery of 5-fluorouracil to skin cancer cells: preparation, characterization, in vitro release, and cytotoxicity analysis. Anticancer Drugs 22:774–82
   PubMed Web of Science ®Google Scholar
• Ammar HO, Salama HA, Ghorab M, Mahmoud AA. (2009). Nanoemulsion as a potential ophthalmic drug delivery system for dorzolamide hydrochloride. AAPS Pharm Sci Tech 10:808–19
   PubMed Web of Science ®Google Scholar
• Bargman H, Hochman J. (2003). Topical treatment of Bowen’s disease with 5-fluorouracil. J Cutan Med Surg 7:101–5
   PubMed Web of Science ®Google Scholar
• Chauhan A, Zubair S, Sherwani A, Owais M. (2012). Aloe vera induced bimimetic assembalage of nucleobase into nanosized particles. Plos One 7:E32049
   PubMed Web of Science ®Google Scholar
• Cosco D, Paolino D, Muzzalupo R, et al. (2009). Novel PEG-coated nisomes based on bola-surfactant as drug carriers for 5-fluorouracil. Biomed Microd 11:1115–25
   PubMed Web of Science ®Google Scholar
• Craig DQM, Barker SA, Banning D. (1995). An investigation into the mechanisms of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Int J Pharm 114:103–10
   Web of Science ®Google Scholar
• Diasio RB, Johnson MR. (2000). The role of pharmacogenetics and pharmacogenomics in cancer chemotherapy with 5-fluorouracil. Pharmacol 61:199–203
   PubMed Web of Science ®Google Scholar
• Elmaghraby GM. (2008). Transdermal delivery of hydrocortisone from eucalyptus oil microemulsion: effects of cosurfactants. Int J Pharm 355:285–92
   PubMed Web of Science ®Google Scholar
• Elmeshad AN, Tadros MI. (2011). Transdermal delivery of an anticancer drug via w/o emulsions based on alkyl polyglycosides and lecithin: design, characterization and in vivo evaluation of the possible irritation potential in rats. AAPS Pharm Sci Tech 12:1–9
   PubMed Web of Science ®Google Scholar
• Fang JY, Hung CF, Fang YP, Chan TF. (2004). Transdermal iontophoresis of 5-fluorouracil combined with electroporation and laser treatment. Int J Pharm 270:241–9
   PubMed Web of Science ®Google Scholar
• Freitas C, Muller RH. (1998). Effect of light and temperature on zeta potential and physical stability in solid lipid nanoparticle (SLN™) dispersions. Int J Pharm 168:221–9
   Web of Science ®Google Scholar
• Gupta RR, Jain SK, Varshney M. (2005). AOT water-in-oil microemulsions as a penetration enhancer in transdermal drug delivery of fluorouracil. Coll Surf B 41:25–32
   PubMed Web of Science ®Google Scholar
• Haq N, Shakeel F, Fars FK, et al. (2013). Development and validation of an isocratic, sensitive and facile RP-HPLC method for rapid analysis of 5-fluorouracil and stability studies under various stress conditions. Asian J Chem 25:7177–82
   Web of Science ®Google Scholar
• Hwangl TL, Fang CL, Chen CH, Fang JY. (2009). Permeation enhancer containing water-in-oil nanoemulsions as carriers for intravesical cisplatin delivery. Pharm Res 26:2314–23
   PubMed Web of Science ®Google Scholar
• Jain N, Akhtar S, Jain GK, et al. (2011). Antiepileptic intranasal amiloride loaded mucoadhesive nanoemulsion: development safety assessment. J Biomed Nanotechnol 7:142–53
   PubMed Web of Science ®Google Scholar
• Khan GM, Hussain A, Hanif RM. (2011). Preparation and evaluation of 5,9 dimethyl-2-cyclopropyl-2-decanol as a penetration enhancer for drugs through rat skin. Pak J Pharm Sci 24:451–7
   PubMed Web of Science ®Google Scholar
• Meidan VM, Walmsley AD, Docker MF, Irwin WJ. (1999). Ultrasound-enhanced diffusion into coupling gel during phonophoresis of 5-fluorouracil. Int J Pharm 185:205–13
   PubMed Web of Science ®Google Scholar
• Rahman Z, Kohli K, Khar RK, et al. (2006). Characterization of 5-fluorouracil microspheres for colonic delivery. AAPS Pharm Sci Tech 7:E47
   PubMed Web of Science ®Google Scholar
• Raza K, Negi P, Takyar S, et al. (2011). Novel dithranol phospholipid microemulsion for topical application: development, characterization and percutaneous absorption studies. J Microencapsul 28:190–9
   PubMed Web of Science ®Google Scholar
• Robins P, Gupta AK. (2002). The use of topical fluorouracil to treat actinic keratosis. Cutis 70:4–7
   PubMed Web of Science ®Google Scholar
• Shafiq S, Shakeel F, Talegaonkar S, et al. (2007). Development and bioavailability assessment of ramipril nanoemulsion formulation. Eur J Pharm Biopharm 66:227–43
   PubMed Web of Science ®Google Scholar
• Shakeel F, Ramadan W, Ahmed MA. (2009). Investigation of true nanoemulsions for transdermal potential of indomethacin: characterization, rheological characteristics and ex vivo skin permeation studies. J Drug Target 17:435–41
   PubMed Web of Science ®Google Scholar
• Shakeel F, Ramadan W. (2010). Transdermal delivery of anticancer drug caffeine from water-in-oil nanoemulsions. Coll Surf B 75:356–62
   PubMed Web of Science ®Google Scholar
• Shakeel F, Shafiq S, Haq N, et al. (2012). Nanoemulsions as potential vehicles for transdermal and dermal delivery of hydrophobic compounds: an overview. Expert Opin Drug Deliv 9:953–74
   PubMed Web of Science ®Google Scholar
• Singh BN, Jayaswal SB. (2008). Iontophoretic delivery of 5-fluorouracil through excised human stratum corneum. Drug Discov Ther 2:128–35
   PubMedGoogle Scholar
• Singh BN, Singh RB, Singh J. (2005). Effects of ionization and penetration enhancers on the transdermal delivery of 5-fluorouracil through excised human stratum corneum. Int J Pharm 298:98–107
   PubMed Web of Science ®Google Scholar
• Spernath A, Aserin A, Ziserman L, et al. (2007). Phosphatidylcholine embedded microemulsions: physical properties and improved Caco-2 cell permeability. J Controlled Release 119:279–90
   PubMed Web of Science ®Google Scholar
• Thomas AM, Kapanen AI, Hare JI, et al. (2011). Development of a liposomal nanoparticle formulation of 5-fluorouracil for parenteral administration: formulation design, pharmacokinetics and efficacy. J Controlled Release 150:212–9
   PubMed Web of Science ®Google Scholar
• Yassin AEB, Anwer MK, Mowafy HA, et al. (2010). Optimization of 5-fluorouracil solid-lipid nanoparticles: a preliminary study to treat colon cancer. Int J Med Sci 7:398–408
   PubMed Web of Science ®Google Scholar
• Zhang Z, Wo Y, Zhang Y, et al. (2012). In vitro study of ethosome penetration in human skin and hypertrophic scar tissue. Nanomed 8:1026–33
   PubMed Web of Science ®Google Scholar
• Zhu L, Ma J, Jia N, et al. (2009). Chitosan coated magnetic nanoparticles as carriers of 5-fluorouracil: preparation, characterization and cytotoxicity studies. Coll Surf B 68:1–6
   PubMed Web of Science ®Google Scholar