Assessment of the drug loading, in vitro and in vivo release behavior of novel pH-sensitive hydrogel

References

• Bajpai SK, Singh S. (2006). Analysis of swelling behavior of poly(methacrylamide-co-methacrylic acid) hydrogels and effect of synthesis conditions on water uptake. React Funct Polym 66:431–40
   Web of Science ®Google Scholar
• Buritova J, Honor P, Chapman V, Besson J-M. (1996). Enhanced effects of co-administered dexamethasone and diclofenac on inflammatory pain processing and associated spinal c-Fos expression in the rat. Pain 64:559–68
   PubMed Web of Science ®Google Scholar
• Cavalieri F, Chiessi E, Villa R, et al. (2008). Novel PVA-based hydrogel microparticles for doxorubicin delivery. Biomacromolecules 9:1967–73
   PubMed Web of Science ®Google Scholar
• Chaturvedi K, Ganguly K, Nadagouda MN, Aminabhavi TM. (2012). Polymeric hydrogels for oral insulin delivery. J Control Release 165:129–38
   PubMed Web of Science ®Google Scholar
• Cursaru B, Teodorescu M, Boscornea C, et al. (2013). Drug absorption and release properties of crosslinked hydrogels based on diepoxy-terminated poly(ethylene glycol)s and aliphatic polyamines – a study on the effect of the gel molecular structure. Mater Sci Eng C 33:1307–14
   PubMed Web of Science ®Google Scholar
• Fedorak RN, Haeberlin B, Empey LR, et al. (1995). Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression. Gastroenterology 108:1688–99
   PubMed Web of Science ®Google Scholar
• Friend DR. (2005). New oral delivery systems for treatment of inflammatory bowel disease. Adv Drug Deliv Rev 57:247–65
   PubMed Web of Science ®Google Scholar
• Guo BL, & Gao QY. (2007). Preparation and properties of a pH/temperature-responsive carboxymethyl chitosan/poly(N-isopropylacrylamide)semi-IPN hydrogel for oral delivery of drugs. Carbohydr Res 342:2416–22
   PubMed Web of Science ®Google Scholar
• Gupta P, Vermani K, & Garg S. (2002). Hydrogels: from controlled release to pH-responsive drug delivery. Drug Discov Today 7:569–79
   PubMed Web of Science ®Google Scholar
• Habraken W, Wolke J, & Jansen J. (2007). Ceramic composites as matrices and scaffolds for drug delivery in tissue engineering. Adv Drug Deliv Rev 59:234–48
   PubMed Web of Science ®Google Scholar
• Hee Kyung JU, So Yeon Kim, & Lee, YM. (2001). pH/temperature-responsive behaviors of semi-IPN and comb-type graft hydrogels composed of alginate and poly(N-isopropylacrylamide). Polymer 42:6851–7, 7
   Web of Science ®Google Scholar
• Hu Y, Zhang L, Cao Y, et al. (2004). Degradation behavior of poly (ε-caprolactone)-b-poly (ethylene glycol)-b-poly (ε-caprolactone) micelles in aqueous solution. Biomacromolecules 5:1756–62
   PubMed Web of Science ®Google Scholar
• Kalarickal NC, Rimmer S, Sarker P, Leroux J-C. (2007). Thiol-functionalized poly (ethylene glycol)-b-polyesters: synthesis and characterization. Macromolecules 40:1874–80
   Web of Science ®Google Scholar
• Keely S, Ryan SM, Haddleton DM, et al. (2009). Dexamethasone–pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers. J Control Rel 135:35–43
   PubMed Web of Science ®Google Scholar
• Kim B, & Peppas NA. (2003). In vitro release behavior and stability of insulin in complexation hydrogels as oral drug delivery carriers. Int J Pharm 266:29–37
   PubMed Web of Science ®Google Scholar
• Langer R, & Peppas NA. (2003). Advances in biomaterials, drug delivery, and bionanotechnology. AIChE J 49:2990–3006
   Web of Science ®Google Scholar
• Li F, Li S, & Vert M. (2005). Synthesis and rheological properties of polylactide/poly (ethylene glycol) multiblock copolymers. Macromol Biosci 5:1125–31
   PubMed Web of Science ®Google Scholar
• Milasinovic N, Knezevic-Jugovic Z, Milosavljevic N, et al. (2012). Controlled release of lipase from Candida rugosa loaded into hydrogels of N-isopropylacrylamide and itaconic acid. Int J Pharm 436:332–40
   PubMed Web of Science ®Google Scholar
• Milašinović N, Kalagasidis Krušić M, Knežević-Jugović Z, et al. (2010). Hydrogels of N-isopropylacrylamide copolymers with controlled release of a model protein. Int J of Pharm 383:53–61
   PubMed Web of Science ®Google Scholar
• Milosavljević NB, Ristić MĐ, Perić-Grujić AA, et al. (2011). Sorption of zinc by novel pH-sensitive hydrogels based on chitosan, itaconic acid and methacrylic acid. J Hazard Mater 192:846–54
   PubMed Web of Science ®Google Scholar
• Nguyen MK, Huynh CT, & Lee DS. (2009). pH-sensitive and bioadhesive poly(β-amino ester)–poly(ethylene glycol)–poly(β-amino ester) triblock copolymer hydrogels with potential for drug delivery in oral mucosal surfaces. Polymer 50:5205–10
   Web of Science ®Google Scholar
• Peppas NA, Wood KM, & Blanchette JO. (2004). Hydrogels for oral delivery of therapeutic proteins. Expert Opin Biol Ther 4:881–7
   PubMed Web of Science ®Google Scholar
• Ranjha NM, Mudassir J, & Akhtar N. (2008). Methyl methacrylate-co-itaconic acid (MMA-co-IA) hydrogels for controlled drug delivery. J Solgel Sci Technol 47:23–30
   Web of Science ®Google Scholar
• Sande SA. (2005). Pectin-based oral drug delivery to the colon. Expert Opin Drug Deliv 2:441–50
   PubMedGoogle Scholar
• Sasatsu M, Onishi H, & Machida Y. (2005). Preparation of a PLA–PEG block copolymer using a PLA derivative with a formyl terminal group and its application to nanoparticulate formulation. Int J Pharm 294:233–45
   PubMed Web of Science ®Google Scholar
• Singh B, Chauhan GS, Kumar S, & Chauhan N. (2007). Synthesis, characterization and swelling responses of pH sensitive psyllium and polyacrylamide based hydrogels for the use in drug delivery (I). Carbohydr Polym 67:190–200
   Web of Science ®Google Scholar
• Taşdelen B, Kayaman-Apohan N, G Ven O, & Baysal BM. (2004). pH-thermoreversible hydrogels. I. Synthesis and characterization of poly(N-isopropylacrylamide/maleic acid) copolymeric hydrogels. Radiat Phys Chem 69:303–10
   Web of Science ®Google Scholar
• Teijon C, Guerrero S, Olmo R, et al. (2009). Swelling properties of copolymeric hydrogels of poly(ethylene glycol) monomethacrylate and monoesters of itaconic acid for use in drug delivery. J Biomed Mater Res B Appl Biomater 91:716–26
   PubMed Web of Science ®Google Scholar
• Van Meeteren M, Meijssen M, & Zijlstra F. (2000). The effect of dexamethasone treatment on murine colitis. Scand J Gastroenterol 35:517–21
   PubMed Web of Science ®Google Scholar
• Wang K, Fu Q, Chen X, et al. (2012a). Preparation and characterization of pH-sensitive hydrogel for drug delivery system. RSC Adv 2:7772–80
   Web of Science ®Google Scholar
• Wang K, Li WF, Xing JF, et al. (2012b). Preliminary assessment of the safety evaluation of novel pH-sensitive hydrogel. Eur J Pharm Biopharm 82:332–9
   PubMed Web of Science ®Google Scholar
• Wang K, Xu X, Liu T, et al. (2010a). Synthesis and characterization of biodegradable pH-sensitive hydrogel based on poly(ε-caprolactone), methacrylic acid, and pluronic (L35). Carbohydr Polym 79:755–61
   Web of Science ®Google Scholar
• Wang K, Xu X, Wang Y, et al. (2010b). Synthesis and characterization of poly(methoxyl ethylene glycol-caprolactone-co-methacrylic acid-co-poly(ethylene glycol) methyl ether methacrylate) pH-sensitive hydrogel for delivery of dexamethasone. Int J Pharm 389:130–8
   PubMed Web of Science ®Google Scholar
• Webber MJ, Matson JB, Tamboli VK, & Stupp SI. (2012). Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response. Biomaterials 33:6823–32
   PubMed Web of Science ®Google Scholar
• Wong TW. (2010). Design of oral insulin delivery systems. J Drug Target 18:79–92
   PubMed Web of Science ®Google Scholar
• Xu FJ, Kang ET, & Neoh KG. (2006). pH- and temperature-responsive hydrogels from crosslinked triblock copolymers prepared via consecutive atom transfer radical polymerizations. Biomaterials 27:2787–97
   PubMed Web of Science ®Google Scholar
• Yang J, Chen J, Pan D, et al. (2012). pH-sensitive interpenetrating network hydrogels based on chitosan derivatives and alginate for oral drug delivery. Carbohydr polym 92:719–25
   PubMed Web of Science ®Google Scholar
• Yin L, Ding J, Fei L, et al. (2008). Beneficial properties for insulin absorption using superporous hydrogel containing interpenetrating polymer network as oral delivery vehicles. Int J Pharm 350:220–9
   PubMed Web of Science ®Google Scholar