The effective combination therapy against human osteosarcoma: doxorubicin plus curcumin co-encapsulated lipid-coated polymeric nanoparticulate drug delivery system

References

• Ahangari A, Salouti M, Heidari Z, et al. (2013). Development of gentamicin-gold nanospheres for antimicrobial drug delivery to Staphylococcal infected foci. Drug Deliv 20:34–9.
   PubMed Web of Science ®Google Scholar
• Brennan P, O'Neill LA. (1998). Inhibition of nuclear factor kappaB by direct modification in whole cells-mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers. Biochem Pharmacol 55:965–73.
   PubMed Web of Science ®Google Scholar
• Chang R, Sun L, Webster TJ. (2014). Short communication: selective cytotoxicity of curcumin on osteosarcoma cells compared to healthy osteoblasts. Int J Nanomed 9:461–5.
   PubMed Web of Science ®Google Scholar
• Chang R, Sun L, Webster TJ. (2015). Selective inhibition of MG-63 osteosarcoma cell proliferation induced by curcumin-loaded self-assembled arginine-rich-RGD nanospheres. Int J Nanomed 10:3351–65.
   PubMed Web of Science ®Google Scholar
• Collins HM, Abdelghany MK, Messmer M, et al. (2013). Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells. BMC Cancer 13:37.
   PubMed Web of Science ®Google Scholar
• Desandes E. (2007). Survival from adolescent cancer. Cancer Treat Rev 33:609–15.
   PubMed Web of Science ®Google Scholar
• Dhule SS, Penfornis P, Frazier T, et al. (2012). Curcumin-loaded γ-cyclodextrin liposomal nanoparticles as delivery vehicles for osteosarcoma. Nanomedicine 8:440–51.
   PubMed Web of Science ®Google Scholar
• Dhule SS, Penfornis P, He J, et al. (2014). The combined effect of encapsulating curcumin and C6 ceramide in liposomal nanoparticles against osteosarcoma. Mol Pharm 11:417–27.
   PubMed Web of Science ®Google Scholar
• Dubey N, Varshney R, Shukla J, et al. (2012). Synthesis and evaluation of biodegradable PCL/PEG nanoparticles for neuroendocrine tumor targeted delivery of somatostatin analog. Drug Deliv 19:132–42.
   PubMed Web of Science ®Google Scholar
• Gao X, Wang B, Wei X, et al. (2013). Preparation, characterization and application of star-shaped PCL/PEG micelles for the delivery of doxorubicin in the treatment of colon cancer. Int J Nanomed 8:971–82.
   PubMed Web of Science ®Google Scholar
• Ganta S, Singh A, Rawal Y, et al. (2015). Formulation development of a novel targeted theranostic nanoemulsion of docetaxel to overcome multidrug resistance in ovarian cancer. Drug Deliv 21:1–13.
   Google Scholar
• Gaudin A, Lepetre-Mouelhi S, Mougin J, et al. (2015). Pharmacokinetics, biodistribution and metabolism of squalenoyl adenosine nanoparticles in mice using dual radio-labeling and radio-HPLC analysis. J Control Release 212:50–8.
   PubMed Web of Science ®Google Scholar
• Li S, Sun W, Wang H, et al. (2015). Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal. Tumour Biol 36:1329–38.
   PubMed Web of Science ®Google Scholar
• Li Y, Su T, Zhang Y, et al. (2015). Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection. Drug Deliv 22:627–37.
   PubMed Web of Science ®Google Scholar
• Liu Y, Li K, Pan J, et al. (2010). Folic acid conjugated nanoparticles of mixed lipid monolayer shell and biodegradable polymer core for targeted delivery of Docetaxel. Biomaterials 31:330–8.
   PubMed Web of Science ®Google Scholar
• Longhi A, Errani C, De Paolis M, et al. (2006). Primary bone osteosarcoma in the pediatric age: state of the art. Cancer Treat Rev 32:423–36.
   PubMed Web of Science ®Google Scholar
• Miao J, Du YZ, Yuan H, et al. (2013). Drug resistance reversal activity of anticancer drug loaded solid lipid nanoparticles in multi-drug resistant cancer cells. Colloids Surf B Biointerfaces 110:74–80.
   PubMed Web of Science ®Google Scholar
• Nedelcu T, Kubista B, Koller A, et al. (2008). Livin and Bcl-2 expression in high-grade osteosarcoma. J Cancer Res Clin Oncol 134:237–44.
   PubMed Web of Science ®Google Scholar
• Parajó Y, D'Angelo I, Welle A, et al. (2010). Hyaluronic acid/chitosan nanoparticles as delivery vehicles for VEGF and PDGF-BB. Drug Deliv 17:596–604.
   PubMed Web of Science ®Google Scholar
• Rajkumar T, Yamuna M. (2008). Multiple pathways are involved in drug resistance to doxorubicin in an osteosarcoma cell line. Anticancer Drugs 19:257–65.
   PubMed Web of Science ®Google Scholar
• Rahman HS, Rasedee A, How CW, et al. (2013). Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect. Int J Nanomed 8:2769–81.
   PubMed Web of Science ®Google Scholar
• Saini D, Fazil M, Ali MM, et al. (2015). Formulation, development and optimization of raloxifene-loaded chitosan nanoparticles for treatment of osteoporosis. Drug Deliv 22:823–36.
   PubMed Web of Science ®Google Scholar
• Schwartz CL, Gorlick R, Teot L, et al. (2007). Multiple drug resistance in osteogenic sarcoma: INT0133 from the Children's Oncology Group. J Clin Oncol 25:2057–62.
   PubMed Web of Science ®Google Scholar
• Siegel R, Naishadham D, Jemal A. (2013). Cancer statistics, 2013. CA Cancer J Clin 63:11–30.
   PubMed Web of Science ®Google Scholar
• Shao Z, Shao J, Tan B, et al. (2015). Targeted lung cancer therapy: preparation and optimization of transferrin-decorated nanostructured lipid carriers as novel nanomedicine for co-delivery of anticancer drugs and DNA. Int J Nanomed 10:1223–33.
   PubMed Web of Science ®Google Scholar
• Susa M, Iyer AK, Ryu K, et al. (2009). Doxorubicin loaded polymeric nanoparticulate delivery system to overcome drug resistance in osteosarcoma. BMC Cancer 9:399.
   PubMed Web of Science ®Google Scholar
• Susa M, Iyer AK, Ryu K, et al. (2010). Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS One 5:e10764.
   PubMed Web of Science ®Google Scholar
• Troselj KG, Kujundzic RN. (2014). Curcumin in combined cancer therapy. Curr Pharm Des 20:6682–96.
   PubMed Web of Science ®Google Scholar
• Wang Y, Liu P, Qiu L, et al. (2013). Toxicity and therapy of cisplatin-loaded EGF modified mPEG-PLGA-PLL nanoparticles for SKOV3 cancer in mice. Biomaterials 34:4068–77.
   PubMed Web of Science ®Google Scholar
• Wu X, Cai ZD, Lou LM, et al. (2012). Expressions of p53, c-MYC, BCL-2 and apoptotic index in human osteosarcoma and their correlations with prognosis of patients. Cancer Epidemiol 36:212–16.
   PubMed Web of Science ®Google Scholar
• Ye YJ, Wang Y, Lou KY, et al. (2015). The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes. Int J Nanomed 10:4309–19.
   PubMed Web of Science ®Google Scholar
• Zaki NM. (2014). Augmented cytotoxicity of hydroxycamptothecin-loaded nanoparticles in lung and colon cancer cells by chemosensitizing pharmaceutical excipients. Drug Deliv 21:265–75.
   PubMed Web of Science ®Google Scholar
• Zhao M, Li A, Chang J, et al. (2013). Develop a novel superparamagnetic nano-carrier for drug delivery to brain glioma. Drug Deliv 20:95–101.
   PubMed Web of Science ®Google Scholar