18
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Turnover of Adrenergic Receptors Under Normal and Desensitized Conditions

, , , , , , & show all
Pages 69-89 | Published online: 26 Sep 2008

References

  • Homburger V., Gozlan H., Bouhelal R., Lucas M., Bockaert J. Irreversible blockade of beta adrenergic receptors with a bromoacetyl derivative of pindolol. Naunyn-Schmiedeberg's Arch. Pharmacol., Submitted
  • Perkins J. P. Desensitization of the response of adenylate cyclase to catecholamines. Current Topics in Membranes and Transport, Vol. 18. Academic Press Inc. 1983; 85–108
  • Catt K. J., Harwood J. P., Aguilera G., Dufau M. L. Hormonal regulation of peptide receptors and target cell responses. Nature 1979; 280: 109–116
  • Goldstein J. L., Anderson R. G.W., Brown M. S. Coated pits, coated vesicles and receptor mediated endocytosis. Nature 1979; 279: 679–685
  • Walaas O., Horn R. S. The controversial problem of insulin action. More about receptors. Current Reviews in Biomedicine, J. W. Lamble, A. W. Cuthbert. Elsevier Biomedical Press. 1982; 148–153
  • Fox C. F., Linsley P. S., Wrann M. Receptor remodeling and regulation in the action of epidermal growth factor. Federation Proc. 1982; 41: 2988–2995
  • Changeux J. P. The acetylcholine receptor : an “allosteric” membrane protein. The Harvey Lectures. Academic Press Inc. 1981; Vol. 75: 85
  • Tzartos S. J., Lindstrom J. N. Monoclonal antibodies used to probe acetylcholine receptor structure : localization of the main immunogenic region and detection of similarities between subunits. Proc. Natl. Acad. Sci. USA 1980; 77: 755–759
  • Fambrough D. M. Control of acetylcholine receptors in skeletal muscle. Physiol. Rev. 1979; 59: 165–227
  • Betz H., Changeux J. P. Regulation of muscle acetylcholine receptor synthesis in vitro by cyclic nucleotide derivatives. Nature 1979; Vol. 278: 749–752
  • Anderson D. J., Blobel G. In vitro synthesis, glycosylation and membrane insertion of torpedo acetylcholine receptor. Proc. Natl. Acad. Sci. USA 1981; 78: 5598–5602
  • Merlie J. P., Hofler J. G., Sebbane R. Acetylcholine receptor synthesis from membrane polysomes. J. Biol. Chem., 256: 6995
  • Anderson D. J. Acetylcholine receptor biosynthesis : from kinetics to molecular mechanism. T.I.N.S. 1983; 169
  • Sebbane R., Clokey G., Merlie J. P. Characterization of the mRNA for mouse muscle acetylcholine receptor alpha subunit by quantitative translation in vitro. J. Biol. Chem. 1983; 258: 3294–3303
  • Mauger J. P., Sladeczek F., Bockaert J. Characteristics and metabolism of alpha1 adrenergic receptors in a non-fusing muscle cell line. J. Biol. Chem. 1982; 257: 875–879
  • Homburger V., Pantaloni C., Lucas M., Gozlan H., Bockaert J. Beta adrenergic receptor repopulation of C6 glioma cells after irreversible blockade and down regulation. J. Cell. Physiol., Submitted
  • Sladeczek F., Bockaert J. Turn-over in vivo of alpha1 adrenergic receptors in rat submaxillary glands. Mol. Pharmacol. 1983; 23: 282–288
  • Kuhman-Clauser D. A. A novel approach to the questions of allosteric properties or “receptor reserve” of drug binding sites of intestinal smooth muscle cells. F.E.B.S. Lett. 1974; 39: 61–66
  • Homburger V., Lucas M., Cantau B., Barabe J., Penit J., Bockaert J. Further evidence that desensitization of beta adrenergic sensitive adenylate cyclase proceeds in two steps. J. Biol. Chem. 1980; 255: 10436
  • Patrick J., McMillan J., Wolfson H., O'Brien J. C. Acetylcholine receptor metabolism in a non-fusing muscle cell line. J. Biol. Chem. 1977; 252: 2143–2153
  • Mauger J. P., Worcel M. Relationship between the (−)-3H-dihydroalprenolol binding to beta adrenergic receptors and transmembrane 86Rb efflux of the BC3H1 non-fusing muscle cell line. Br. J. Pharmacol. 1980; 68: 731–739
  • Standaert M. L., Schimmel S. D., Pollet R. J. The development of insulin receptor and responses in the differentiating non-fusing muscle cell line BC3H1. J. Biol. Chem. 1984; 259: 2337–2345
  • Olson E. N., Glaser L., Merlie J. P., Lindstrom J. Expression of acetylcholine receptor alpha-subunit mRNA during differentiation of the BC3H1 muscle cell line. J. Biol. Chem. 1984; 259: 3330–3336
  • Hamilton C. A., Dalrymple H. W., Reid J. L., Sumner D. J. The recovery of alpha-adrenoceptor function and binding sites after phenoxybenzamine. Naunyn-Schmiedeberg's Arch. Pharmacol. 1984; 325: 34–41
  • McKernan R. M., Campbell I. C. Measurement of alpha-adrenoceptor “turn-over” using phenoxybenzamine. Eur. J. Pharmacol. 1982; 80: 279–280
  • Lynch C. J., Deth R. C., Steer M. L. Simultaneous loss and reappearance of alpha1 adrenergic responses and 3H-prazosin binding sites in rat liver after irreversible blockade by phenoxybenzamine. Biochim. Biophys. Acta. 1983; 757: 156–163
  • Bockaert J., Lucas M. Coupling of beta adrenergic receptors with adenylate cyclase in C6 glioma cells. Recent Advances in Cyclic Nucleotide Research, E. Szabadi, L. M. Bradshaw, P. Bevan. Elsevier/North-Holland Biomedical Press. 1978
  • Harden T. K., Foster S. J., Perkins J. P. Differential expression of components of the adenylate cyclase system during growth of astrocytoma cells in culture. J. Biol. Chem. 1979; 254: 4416–4422
  • Baker S. P., Pitha J. Irreversible blockade of beta adrenoceptors and their recovery in rat heart and lung in vivo. J. Pharmacol. Exp. Ther. 1982; 220: 247–252
  • Pitha J., Hughes B. A., Kusiak J. W., Dax E., Baker Regeneration S. P. beta adrenergic receptors in senescent rats a study using an irreversible binding antagonist. Proc. Natl. Acad. Sci. USA 1982; 4424
  • Fraser C. M., Venter J. C. The synthesis of beta adrenergic receptors in cultured human lung cells : induction by glucocorticoids. Biochem. Biophys. Res. Commun. 1980; 94: 390–397
  • Doss R. C., Perkins J. P., Harden T. K. Recovery of beta adrenergic receptors following long-term exposure of astrocytoma cells to catecholamine. J. Biol. Chem. 1981; 256: 12281–12286
  • Shorr R. G.L., Lefkowitz R. J., Caron M. G. Purification of the beta adrenergic receptor. J. Biol. Chem. 1981; 256: 5820–5826
  • Gardner J. M., Fambrough D. M. Acetylcholine receptor degradation measured by density labeling : effects of cholinergic ligands and evidence against recycling. Cell 1979; 16: 661–674

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.