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Research Article

A novel approach to determine solid fraction using a laser-based direct volume measurement device

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Pages 577-582 | Received 15 Dec 2012, Accepted 13 May 2013, Published online: 12 Aug 2013

References

  • Amidon GE, Secreast PJ, Mudie D. Particle, powder & compact characterization. In: Qiu Y, Liu L, Chen Y, et al., eds. Developing solid oral dosage forms: pharmaceutical theory & practice. New York: Elsevier Academic Press; 2009:176–183
  • Tye CK, Sun CC, Amidon GE. Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction. J Pharm Sci 2005;94:465–472
  • Hancock BC, Colvin JT, Mullarney MP, Zinchuk AV. The relative densities of pharmaceutical powders, blends, dry granulations, and immediate-release tablets. Pharm Tech 2003;27:64–80
  • Akseli, I, Iyer S, Lee HP, Cuitiño AM. A quantitative correlation of the effect of density distributions in roller-compacted ribbons on the mechanical properties of tablets using ultrasonics and X-ray tomography. AAPS PharmSciTech 2011;12:834–853

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