Pharmaceutical Development and Technology, Volume 19, Issue 5 (2014)

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Pharmaceutical Development and Technology, Volume 19, Issue 5 (2014)

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Research Article

Article
Physicochemical and structural characterization of iron–sucrose formulations: a comparative study
Bhavesh S. Barot, Punit B. Parejiya, Dharmik M. Mehta, Pragna K. Shelat & Gaurang B. Shah
Pages: 513-520
Published online: 24 May 2013
AbstractforPhysicochemical and structural characterization of iron–sucrose formulations: a comparative study | Full Text | References | PDF (846.7 KB)
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Original Research

Article
Novel delivery approach for ketotifen fumarate: dissofilms formulation using 32 experimental design: in vitro/in vivo evaluation
Rania H. Fahmy & Shaimaa M. Badr-Eldin
Pages: 521-530
Published online: 28 May 2013
AbstractforNovel delivery approach for ketotifen fumarate: dissofilms formulation using 32 experimental design: in vitro/in vivo evaluation | Full Text | References | PDF (1.7 MB)
  • 208 Views
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Research Article

Article
Diclofenac sodium sustained release hot melt extruded lipid matrices
K. Vithani, Y. Cuppok, S. Mostafa, I. J. Slipper, M. J. Snowden & D. Douroumis
Pages: 531-538
Published online: 13 Jun 2013
AbstractforDiclofenac sodium sustained release hot melt extruded lipid matrices | Full Text | References | PDF (1.6 MB)
  • 231 Views
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Article
Release optimization of epidermal growth factor from PLGA microparticles
Omolbanin Mirdailami, Mohammad Reza Khoshayand, Masoud Soleimani, Rassoul Dinarvand & Fatemeh Atyabi
Pages: 539-547
Published online: 19 Jun 2013
AbstractforRelease optimization of epidermal growth factor from PLGA microparticles | Full Text | References | PDF (1.5 MB)
  • 268 Views
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Article
The influence of sodium salts (iodide, chloride and sulfate) on the formation efficiency of sulfamerazine nanocrystals
Hao Lou, Min Liu, Wen Qu, James Johnson, Ed. Brunson & Hassan Almoazen
Pages: 548-555
Published online: 13 Jun 2013
AbstractforThe influence of sodium salts (iodide, chloride and sulfate) on the formation efficiency of sulfamerazine nanocrystals | Full Text | References | PDF (650.7 KB)
  • 168 Views
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Article
Application of active layering and coating techniques in the development of a multiparticulate, controlled release dosage form of a high-dose, highly soluble drug
Haitham Ahmad, Ismail Khalifeh, Bashar Alkhalidi, Khaled Aiedeh & Hatim S. AlKhatib
Pages: 556-564
Published online: 14 Jun 2013
AbstractforApplication of active layering and coating techniques in the development of a multiparticulate, controlled release dosage form of a high-dose, highly soluble drug | Full Text | References | PDF (1.2 MB)
  • 235 Views
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Article
Impacts of chemical enhancers on skin permeation and deposition of terbinafine
Meryem Sedef Erdal, Ayca Yıldız Peköz, Buket Aksu & Ahmet Araman
Pages: 565-570
Published online: 10 Jul 2013
AbstractforImpacts of chemical enhancers on skin permeation and deposition of terbinafine | Full Text | References | PDF (875.2 KB)
  • 398 Views
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Article
Development of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties
Darren Svirskis, Ali Seyfoddin, Suna Chalabi, Joanne Hye In Kim, Christopher Langford, Sivani Painter & Raida Al-Kassas
Pages: 571-576
Published online: 17 Jul 2013
AbstractforDevelopment of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties | Full Text | References | PDF (508.7 KB)
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Article
A novel approach to determine solid fraction using a laser-based direct volume measurement device
Raman Mahadevan Iyer, Shridhar Hegde, Dharmendra Singhal & Waseem Malick
Pages: 577-582
Published online: 12 Aug 2013
AbstractforA novel approach to determine solid fraction using a laser-based direct volume measurement device | Full Text | References | PDF (944.3 KB)
  • 187 Views
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Technical Note

Article
The impact of roller compaction and tablet compression on physicomechanical properties of pharmaceutical excipients
Raman Mahadevan Iyer, Shridhar Hegde, James DiNunzio, Dharmendra Singhal & Waseem Malick
Pages: 583-592
Published online: 14 Aug 2013
AbstractforThe impact of roller compaction and tablet compression on physicomechanical properties of pharmaceutical excipients | Full Text | References | PDF (1.4 MB)
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Research Article

Article
Preparation and characterization of self-assembled chitosan nanoparticles for the sustained delivery of streptokinase: an in vivo study
Seyed Mohamad Sadegh Modaresi, Shahram Ejtemaei Mehr, Mohammad Ali Faramarzi, Elina Esmaeilzadeh Gharehdaghi, Mahnaz Azarnia, Mohammad Hossein Modarressi, Hadi Baharifar, Seyed Javad Vaez & Amir Amani
Pages: 593-597
Published online: 17 Jul 2013
AbstractforPreparation and characterization of self-assembled chitosan nanoparticles for the sustained delivery of streptokinase: an in vivo study | Full Text | References | PDF (738.3 KB)
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Article
Using principal component analysis in studying the transdermal delivery of a lipophilic drug from soft nano-colloidal carriers to develop a quantitative composition effect permeability relationship
Rania M. Hathout
Pages: 598-604
Published online: 24 Jul 2013
AbstractforUsing principal component analysis in studying the transdermal delivery of a lipophilic drug from soft nano-colloidal carriers to develop a quantitative composition effect permeability relationship | Full Text | References | PDF (590.5 KB)
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Article
Novel lectin-modified poly(ethylene-co-vinyl acetate) mucoadhesive nanoparticles of carvedilol: preparation and in vitro optimization using a two-level factorial design
Jaleh Varshosaz & Ellaheh Moazen
Pages: 605-617
Published online: 13 Aug 2013
AbstractforNovel lectin-modified poly(ethylene-co-vinyl acetate) mucoadhesive nanoparticles of carvedilol: preparation and in vitro optimization using a two-level factorial design | Full Text | References | PDF (1.6 MB)
  • 164 Views
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Article
Mometasone furoate hydrogel for scalp use: in vitro and in vivo evaluation
Ana Salgado, Sara Raposo, Joana Marto, Alexandra N. Silva, Sandra Simões & Helena M. Ribeiro
Pages: 618-622
Published online: 22 Jul 2013
AbstractforMometasone furoate hydrogel for scalp use: in vitro and in vivo evaluation | Full Text | References | PDF (322.1 KB)
  • 220 Views
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Original Research

Article
Pulmonary delivery of nanosized alendronate for decorporation of inhaled heavy metals: formulation development, characterization and gamma scintigraphic evaluation
Shaheen Sultana, Aseem Bhatnagar, Harish Rawat, Dhruv Kumar Nishad, Sushma Talegaonkar, Farhan Jalees Ahmad & Gaurav Mittal
Pages: 623-633
Published online: 25 Jul 2013
AbstractforPulmonary delivery of nanosized alendronate for decorporation of inhaled heavy metals: formulation development, characterization and gamma scintigraphic evaluation | Full Text | References | PDF (1.2 MB)
  • 185 Views
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Research Article

Article
Numerical solution for 5-layer laminate technique to determine saturation solubility of a drug in a thin film of pressure sensitive adhesive
Eberhard Bänsch, Simone Reismann & Geoffrey Lee
Pages: 634-640
Published online: 15 Aug 2013
AbstractforNumerical solution for 5-layer laminate technique to determine saturation solubility of a drug in a thin film of pressure sensitive adhesive | Full Text | References | PDF (842.5 KB)
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