Using principal component analysis in studying the transdermal delivery of a lipophilic drug from soft nano-colloidal carriers to develop a quantitative composition effect permeability relationship

References

• Changez M, Varshney M. Aerosol-OT microemulsions as transdermal carriers of tetracaine hydrochloride. Drug Dev Ind Pharm 2000;26:507–512
   PubMed Web of Science ®Google Scholar
• Hathout RM, ElShafeey AH. Development and characterization of colloidal soft nano-carriers for transdermal delivery and bioavailability enhancement of an angiotensin II receptor blocker. Eur J Pharm Biopharm 2012;82:230–240
   PubMed Web of Science ®Google Scholar
• Hathout RM, Woodman TJ. Applications of NMR in the characterization of pharmaceutical microemulsions. J Control Release 2012;161:62–72
   PubMed Web of Science ®Google Scholar
• Hathout RM, Woodman TJ, Mansour S, et al. Microemulsion formulations for the transdermal delivery of testosterone. Eur J Pharm Sci 2010;40:188–196
   PubMed Web of Science ®Google Scholar
• McClements DJ. Nanoemulsions versus microemulsions: terminology, differences, and similarities. Soft matter 2012;8:1719–1729
   Web of Science ®Google Scholar
• Moss GP, Shah AJ, Adams RG, et al. The application of discriminant analysis and Machine Learning methods as tools to identify and classify compounds with potential as transdermal enhancers. Eur J Pharm Sci 2012;45:116–127
   PubMed Web of Science ®Google Scholar
• Pratiwi D, Fawcett JP, Gordon KC, Rades T. Quantitative analysis of polymorphic mixtures of ranitidine hydrochloride by Raman spectroscopy and principal components analysis. Eur J Pharm Biopharm 2002;54:337–341
   PubMedGoogle Scholar
• Gad HA, El-Ahmady SH, bou-Shoer MI, Al-Azizi MM. Application of chemometrics in authentication of herbal medicines: a review. Phytochem Anal 2013;1:1–24
   Google Scholar
• Martins S, Tho I, Souto E, et al. Multivariate design for the evaluation of lipid and surfactant composition effect for optimisation of lipid nanoparticles. Eur J Pharm Sci 2012;45:613–623
   PubMed Web of Science ®Google Scholar
• Singh SK, Verma PR, Razdan B. Development and characterization of a lovastatin-loaded self-microemulsifying drug delivery system. Pharm Dev Technol 2010;15:469–483
   PubMed Web of Science ®Google Scholar
• Hathout RM, Mansour S, Mortada ND, et al. Uptake of microemulsion components into the stratum corneum and their molecular effects on skin barrier function. Mol Pharm 2010;7:1266–1273
   PubMed Web of Science ®Google Scholar
• Hathout RM, Mansour S, Geneidi AS, Mortada ND. Visualization, dermatopharmacokinetic analysis and monitoring the conformational effects of a microemulsion formulation in the skin stratum corneum. J Colloid Interface Sci 2011;354:124–130
   PubMed Web of Science ®Google Scholar
• Klang V, Schwarz JC, Lenobel B, et al. In vitro vs. in vivo tape stripping: validation of the porcine ear model and penetration assessment of novel sucrose stearate emulsions. Eur J Pharm Biopharm 2012;80:604–614
   PubMed Web of Science ®Google Scholar
• Chen H, Chang X, Weng T, et al. A study of microemulsion systems for transdermal delivery of triptolide. J Control Release 2004;98:427–436
   PubMed Web of Science ®Google Scholar
• Garti N, Clement V, Fanun M, Leser ME. Some characteristics of sugar ester nonionic microemulsions in view of possible food applications. J Agric Food Chem 2000;48:3945–3956
   PubMed Web of Science ®Google Scholar
• Bommannan D, Potts RO, Guy RH. Examination of stratum-corneum barrier function invivo by infrared-spectroscopy. J Invest Dermatol 1990;95:403–408
   PubMed Web of Science ®Google Scholar
• Jadoul A, Bouwstra J, Preat V. Effects of iontophoresis and electroporation on the stratum corneum – review of the biophysical studies. Adv Drug Deliv Rev 1999;35:89–105
   PubMed Web of Science ®Google Scholar
• Mendelsohn R, Flach CR, Moore DJ. Determination of molecular conformation and permeation in skin via IR spectroscopy, microscopy, and imaging. Biochim Biophys Acta – Biomembranes 2006;1758:923–933
   PubMed Web of Science ®Google Scholar
• Karande P, Jain A, Ergun K, et al. Design principles of chemical penetration enhancers for transdermal drug delivery. Proc Natl Acad Sci USA 2005;102:4688–4693
   PubMed Web of Science ®Google Scholar
• Potts RO, Golden GM, Francoeur ML, et al. Mechanism and enhancement of solute transport across the stratum-corneum. J Control Release 1991;15:249–260
   Web of Science ®Google Scholar
• Singh SK, Verma PR, Razdan B. Glibenclamide-loaded self-nanoemulsifying drug delivery system: development and characterization. Drug Dev Ind Pharm 2010;36:933–945
   PubMed Web of Science ®Google Scholar
• Friend DR. In vitro skin permeation techniques. J Control Release 1992;18:235–248
   Web of Science ®Google Scholar
• Sekkat N, Kalia YN, Guy RH. Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates. Pharm Res 2004;21:1390–1397
   PubMed Web of Science ®Google Scholar
• Stone M. Cross-validatory choice and assessment of statistical predictions. J R Stat Soc Series B Stat Methodol 1974;36:111–147
   Web of Science ®Google Scholar
• Naik A, Pechtold LARM, Potts RO, Guy RH. Mechanism of oleic acid-induced skin penetration enhancement in vivo in humans. J Control Release 1995;37:299–306
   Web of Science ®Google Scholar
• Araya H, Tomita M, Hayashi M. The novel formulation design of O/W microemulsion for improving the gastrointestinal absorption of poorly water soluble compounds. Int J Pharm 2005;305:61–74
   PubMed Web of Science ®Google Scholar
• Naik A, Kalia YN, Guy RH. Transdermal drug delivery: overcoming the skin’s barrier function. Pharm Sci Technolo Today 2000;3:318–326
   PubMedGoogle Scholar
• Leichtnam ML, Rolland H, Wuthrich P, Guy RH. Enhancement of transdermal testosterone delivery by supersaturation. J Pharm Sci 2006;95:2373–2379
   PubMed Web of Science ®Google Scholar
• Rhee YS, Huh JY, Park CW, et al. Effects of vehicles and enhancers on transdermal delivery of clebopride. Arch Pharm Res 2007;30:1155–1161
   PubMed Web of Science ®Google Scholar
• Trommer H, Neubert RHH. Overcoming the stratum corneum: the modulation of skin penetration – a review. Skin Pharmacol Physiol 2006;19:106–121
   PubMed Web of Science ®Google Scholar
• Zulfakar MH, Abdelouahab N, Heard CM. Enhanced topical delivery and ex vivo anti-inflammatory activity from a betamethasone dipropionate formulation containing fish oil. Inflamm Res 2010;59:23–30
   PubMed Web of Science ®Google Scholar
• Rossi RJ. Describing populations. In: Rossi RJ, ed. Applied statistics for the health science. Hoboken (NJ): John Wiley and Sons, Inc.; 2010:22–75
   Google Scholar
• Wold S, Johansson E, Cocchi M. PLS-Partial square analysis. In: Kubinyi H, ed. 3D QSAR in drug design: Volume 1: Theory methods and applications. Dordrecht: Kluwer Academic Publishers. The Netherlands; 2000:523–550
   Google Scholar