References
- Rozier A, Mazuel C, Grove J, Plazonnet B. Gelrite: a novel, ionactivated, in-situ gelling polymer for ophthalmic vehicles. Effect on bioavailability of timolol. Int J Pharm 1989;57:163–168
- Cohen S, Lobel E, Trevgoda A, Peled Y. A novel in situ-forming ophthalmic drug delivery system from alginates undergoing gelation in the eye. J Control Release 1997;44:201–208
- Kumar S, Haglund BO, Himmelstein KJ. In situ-forming gels for ophthalmic drug delivery. J Ocul Pharmacol 1994;10:47–56
- Srividya B, Cardoza RM, Amin PD. Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system. J Control Release 2001;73:205–211
- Ruel-Gariépy E, Leroux J-C. In situ-forming hydrogels – review of temperature-sensitive systems. Eur J Pharm Biopharm 2004;58:409–426
- Hoffman AS. Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostic. J Control Release 1987;6:297–305
- Hoffman AS, Afrassiabi A, Dong LC. Thermally reversible hydrogels: II. Delivery and selective removal of substances from aqueous solutions. J Control Release 1986;4:213–222
- Hirotsu S, Hirokawa Y, Tanaka T. Volume-phase transitions of ionized N-isopropylacrylamide gels. J Chem Phys 1987;87:1392–1395
- Bohorquez M, Koch C, Trygstad T, Pandit N. A study of the temperature-dependent micellization of pluronic F127. J Colloid Interface Sci 1999;216:34–40
- Cabana A, Ait-Kadi A, Juhasz J. Study of the gelation process of polyethylene oxide-polypropylene oxide-polyethylene oxide copolymer (poloxamer 407) aqueous solutions, J Colloid Interface Sci 1997;190:307–312
- Choi HG, Jung JH, Ryu JM, et al. Development of in situ-gelling and mucoadhesive acetaminophen liquid suppository. Int J Pharm 1998;165:33–44
- Jeong B, Bae YH, Lee DS, Kim SW. Biodegradable block copolymers as injectable drug-delivery systems. Nature 1997;388:860–862
- Jeong B, Bae YH, Kim SW. Biodegradable thermosensitive micelles of PEG-PLGA-PEG triblock copolymers. Colloids Surf 1999;B16:185–193
- Koffi AA, Agnely F, Ponchel G, Grossiord JL. Modulation of the rheological and mucoadhesive properties of thermosensitive poloxamer-based hydrogels intended for the rectal administration of quinine. Eur J Pharm Sci 2006;27:328–335
- Morishita M, Barichello JM, Takayama K, et al. Pluronic F-127 gels incorporating highly purified unsaturated fatty acids for buccal delivery of insulin. Int J Pharm 2001;212:289–293
- Derakhshandeh K, Fashi M, Seifoleslami S. Thermosensitive Pluronic® hydrogel: prolonged injectable formulation for drug abuse. Drug Des Devel Ther 2010;4:255–262
- Huang CH, Tokumura T, Machida Y, Nagai, T. Formulation of double-layered suppository for prolonged stay in lower rectum. Yakuzaigaku 1987;47:42–48
- Ermis D, Tarimci N. Ketoprofen sustained-release suppositories containing hydroxypropylmethylcellulose phthalate in polyethylene glycol bases. Int J Pharm 1995;113:65–71
- Babar A, Bellete T, Plakogiannis FM. Ketoprofen suppository dosage forms: in vitro release and in vivo absorption studies in rabbits. Drug Dev Ind Pharm 1999;25:241–245
- Özgüney I, Özcan İ, Ertan G, Güneri T. The preparation and evaluation of sustained release suppositories containing ketoprofen and Eudragit RL 100 by using factorial design. Pharm Dev Technol 2007;12:97–107
- Choi HG, Lee MK, Kim MH, Kim CK. Effect of additives on the physicochemical properties of liquid suppository bases. Int J Pharm 1999;190:13–19
- Choi HG, Oh YK, Kim CK. In-situ gelling and mucoadhesive liquid suppository containing acetaminophen: enhanced bioavailability. Int J Pharm 1998;165:23–32
- Yong CS, Choi JS, Quan QZ, et al. Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium. Int J Pharm 2001;226:195–205
- Schmolka I. Artificial skin, preparation and properties of Pluronic F-127 gels for the treatment of the burns. J Biomed Mater Res 1972;6:571–582
- Miyazaki S, Nakamura T, Takada M. Thermo-sensitive sol-gel transition of Pluronic F-127. Yakuzaigaku 1991;51:36–43
- Jones DS, Woolfson AD, Brown AF, O’Neill MJ. Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: in vitro release kinetics, syringeability, mechanical and mucoadhesive properties. J Control Release 1997;49:71–79
- Baloglu E, Karavana SY, Senyigit ZA, Guneri T. Rheological and mechanical properties of poloxamer mixtures as a mucoadhesive gel base. Pharm Dev Technol 2011;16:627–636
- Schick MJ. Configuration of the polyoxyethylene chain in bulk, nonionic surfactant. Surfactant Sci 1966;1:753–793
- Kramaric A, Resman A, Kofler B, Zmitek J. Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation. European Patent 1992;0551626(A1)
- Ryu JM, Chung SJ, Lee MH, et al. Increased bioavailability of propranolol in rats by retaining thermally gelling liquid suppositories in the rectum. J Control Release 1999;59:163–172
- Gilbert JC, Richardson JL, Davies MC, et al. The effect of solutes and polymers on the gelation properties of pluronic F-127 solutions for controlled drug delivery. J Control Release 1987;5:113–118
- ElHady SSA, Mortada ND, Awad GAS, et al. Development of in situ gelling and mucoadhesive mebeverine hydrochloride solution for rectal administration. Saudi Pharmaceut J 2003;11:159–171
- Tan YTF, Peh KK, Al-Hanbali O. Effect of carbopol and polyvinylpyrrolidone on the mechanical, rheological, and release properties of bioadhesive polyethylene glycol gels. AAPS Pharm Sci Tech 2000;1:1–10 E24
- Jones DS, Woolfson AD, Djokic J. Texture profile analysis of bioadhesive polymeric semisolids: mechanical characterization and investigation of interactions between formulation components. J Appl Polym Sci 1996;61:2229–2234
- Jones DS, Woolfson AD, Brown AF. Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. Int J Pharm 1997;151:223–233
- Karavana SY, Senyigit ZA, Hilmioglu-Polat S, et al. Mucoadhesive in situ gel formulations of miconazole nitrate for the treatment of mucosal candidiasis. Lat Am J Pharm 2012;31:821–829
- Karavana SY, Güneri P, Ertan G. Benzydamine hydrochloride buccal bioadhesive gels designed for oral ulcers: preparation, rheological, textural, mucoadhesive and release properties. Pharm Dev Technol 2009;14:623–631
- Jones DS, Irwin CR, Woolfson AD, et al. Physicochemical and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis. J Pharm Sci 1999;88:592–598
- Baloglu E, Karavana SY, Senyigit ZA, et al. In-situ gel formulations of econazole nitrate: preparation and in-vitro and in-vivo evaluation. J Pharm Pharmacol 2011;63:1274–1282
- Lucero MJ, Vigo J, Leon MJ. A study of shear and compression deformations on hydrophilic gels of tretinoin. Int J Pharm 1994;106:125–133
- Woolfson AD, McCafferty DF, Gorman SP, et al. Design of a linear variable differential transformer for the measurement of type III bioadhesion to cervical tissue. Int J Pharm 1992;84:69–76
- Jones DS, Woolfson AD, Brown AF. Textural analysis and flow rheometry of bioadhesive, antimicrobial oral gels. Pharm Res 1997;14:450–457
- Efentakis M, Koutlis A, Vlachou M. Development and evaluation of oral multiple-unit and single-unit hydrophilic controlled-release systems. AAPS Pharm Sci Tech 2000;1:62--70
- Kunisawa J, Okudaira A, Tsutusmi Y, et al. Characterization of mucoadhesive microspheres for the induction of mucosal and systemic immune responses. Vaccine 2000;19:589–594