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Research Article

Preparation and evaluation of luteolin–phospholipid complex as an effective drug delivery tool against GalN/LPS induced liver damage

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Pages 475-486 | Received 21 Nov 2014, Accepted 16 Feb 2015, Published online: 01 Apr 2015

References

  • Manach C, Williamson G, Morand C, et al. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 2005;81:230S–242S
  • Teng Z, Yuan C, Zhang F, et al. Intestinal absorption and first-pass metabolism of polyphenol compounds in rat and their transport dynamics in Caco-2 cells. PLoS One 2012;7:1–9
  • Singh A, Saharan VA, Singh M, Bhandari A. Phytosome: drug delivery system for polyphenolic phytoconstituents. Iran J Pharm Sci 2011;7:209–219
  • Erba D, Riso P, Bordoni A, et al. Effectiveness of moderate green tea consumption on antioxidative status and plasma lipid profile in humans. J Nutr Biochem 2005;16:144–149
  • Rathore P, Swami G. Planterosomes: a potential phyto-phospholipid carriers for the bioavailability enhancement of herbal extracts. Int J Pharm Sci Res 2012;3:737–755
  • Kidd PM. Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. Altern Med Rev 2009;14:226–246
  • Kidd P, Head K. A review of the bioavailability and clinical efficacy of milk thistle phytosome: a silybin–phosphatidylcholine complex (Siliphos). Altern Med Rev 2005;10:193–203
  • Chen ZP, Sun J, Chen HX, et al. Comparative pharmacokinetics and bioavailability studies of quercetin, kaempferol and isorhamnetin after oral administration of Ginkgo biloba extracts, Ginkgo biloba extract phospholipid complexes and Ginkgo biloba extract solid dispersions in rats. Fitoterapia 2012;81:1045–1052
  • Tan Q, Liu S, Chen X, et al. Design and evaluation of a novel evodiamine–phospholipid complex for improved oral bioavailability. AAPS PharmSciTech 2012;13:534–547
  • Shyam KR, Mruthunjaya K, Gupta MK. Preparation, characterization and antioxidant activities of gallic acid phospholipids complex. Int J Res Pharm Sci 2012;2:138–148
  • Singh D, Rawat MSM, Semalty A, Semalty M. Emodin–phospholipid complex. J Therm Anal Calorim 2012;108:289–298
  • Goda T, Goto Y, Ishihara K. Cell-penetrating macromolecules: direct penetration of amphipathic phospholipid polymers across plasma membrane of living cells. Biomaterials 2012;31:2380–2387
  • Gupta B, Levchenko TS, Torchilin VP. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Deliv Rev 2005;57:637–651
  • FDA Report. Review of the Health Aspects of Lecithin as a Food Ingredient, Vol. 751. Silver Spring, MD: FDA; 1977:78–275
  • Semalty A, Semalty M, Rawat MSM, Franceschi F. Supramolecular phospholipids–polyphenolics interactions: the PHYTOSOME strategy to improve the bioavailability of phytochemicals. Fitoterapia 2010;81:306–314
  • Silky, Kapoor DS, Sarvesh M, et al. Potential and promises of phospholipid structured novel formulations for hepatoprotection. Int J Drug Dev Res 2012;4:51–58
  • Moiteiro C, Gaspar H, Rodrigues AI, et al. HPLC quantification of dye flavonoids in Reseda luteola L. Portugal. J Sep Sci 2008;31:3683–3687
  • Liu R, Meng F, Zhang L, et al. Luteolin isolated from the medicinal plant Elsholtzia rugulosa (Labiatae) prevents copper-mediated toxicity in β-amyloid precursor protein swedish mutation overexpressing SH-SY5Y cells. Molecules 2011;16:2084–2096
  • Farombi EO, Owoeye O. Antioxidative and Chemopreventive Properties of Vernonia amygdalina and Garcinia biflavonoid. Int J Environ Res Public Health 2011;8:2533–2555
  • Etherton PMK, Hecker KD, Bonanome A, et al. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 2002;113:S71–S88
  • Wang TT, Wang SK, Huang GL, Sun GJ. Luteolin induced-growth inhibition and apoptosis of human esophageal squamous carcinoma cell line Eca109 cells in vitro. Asian Pac J Cancer Prev 2012;13:5455–5461
  • Sadik CD, Sies H, Schewe T. Inhibition of 15-lipoxygenases by flavonoids: structure–activity relations and mode of action. Biochem Pharmacol 2003;65:773–781
  • Moreno DA, Ilic N, Poulev A, Raskin I. Effects of Arachis hypogaea nutshell extract on lipid metabolic enzymes and obesity parameters. Life Sci 2006;78:2797–2803
  • Wang GG, Lu XH, Li W, et al. Protective effects of luteolin on diabetic nephropathy in STZ-induced diabetic rats. Evid Based Complement Alternat Med 2011;2011:323171
  • Park CM, Park JY, Noh KH, et al. Taraxacum officinale Weber extracts inhibit LPS-induced oxidative stress and nitric oxide production via the NF-κB modulation in RAW 264.7 cells. J Ethnopharmacol 2011;133:834–842
  • Wang X. Pharmacokinetic interaction between the flavonoid luteolin and γ-hydroxybutyrate in rats: potential involvement of monocarboxylate transporters. AAPS J 2008;10:47–55
  • Chen T, Ping L, Lu XY, et al. Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract. J Agric Food Chem 2007;55:273–277
  • Khan J, Alexander A, Ajazuddin, et al. Recent advances and future prospects of phyto-phospholipid complexation technique for improving pharmacokinetic profile of plant actives. J Control Release 2013;168:50–60
  • Xu K, Liu B, Ma Y, et al. Physicochemical properties and antioxidant activities of luteolin-phospholipid complex. Molecules 2009;14:3486–3493
  • Farghali H, Cerny D, Kameníkova L, et al. Resveratrol attenuates lipopolysaccharide-induced hepatitis in D-galactosamine sensitized rats: role of nitric oxide synthase 2 and heme oxygenase-1. Nitric Oxide 2009;21:216–225
  • Yang WJ, Zhengyi GU, Dilnur T, et al. Protection of Citrullus colocynthis fruit extracts on carbon tetrachloride-induced and Bacillus calmette-guerin plus lipopolysaccharide-induced hepatotoxicity in mice. Chin Herb Med 2013;5:205–211
  • Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol 1957;28:56–63
  • Delannoy M, Del Balzo G, Filippini F, et al. Arterial hypertension modeled by in vitro treatment of red blood cells with trypsin. Ser Biomech 2012;27:87–92
  • Changediya V, Khadke M, Devdhe S. Phytosomes: new approach for delivering herbal drug with improved bioavailability. Res J Pharm Biol Chem Sci 2011;2:57–68
  • Qin X, Yang Y, Fan TT, et al. Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex. Acta Pharmacol Sin 2010;31:127–136
  • Li Y, Yang DJ, Chen SL, et al. Comparative physicochemical characterization of phospholipids complex of puerarin formulated by conventional and supercritical methods. Pharm Res 2008;25:563–577
  • Pathan RA, Bhandari U. Gymnemic acid-phospholipid complex: preparation and characterization. J Dispers Sci Technol 2011;32:1165–1172
  • Ulbrich W, Lamprecht A. Targeted drug-delivery approaches by nanoparticulate carriers in the therapy of inflammatory diseases. J R Soc Interface 2010;7:55–66
  • Shaji J, Lal M. Nanocarriers for targeting in inflammation. Asian J Pharm Clin Res 2013;6:3–12
  • Puhl AC, Fagundes M, Karen CS, et al. Preparation and characterization of polymeric nanoparticles loaded with the flavonoid luteolin, by using factorial design. Int J Drug Deliv 2011;3:683–698
  • Yanyu X, Yunmei X, Zhipeng C, Qinen P. The preparation of silybin–phospholipid complex and the study on its pharmacokinetics in rats. Int J Pharm 2008;307:77–82
  • Lee WC, Jung HA, Choi JS, et al. Protective effects of luteolin against apoptotic liver damage induced by D-galactosamine/lipopolysaccharide in mice. J Nat Prod 2011;74:1916–1921
  • Lekic N, Černý D, Horinek A, et al. Differential oxidative stress responses to D-galactosamine-lipopolysaccharide hepatotoxicity based on real time PCR analysis of selected oxidant/antioxidant and apoptotic gene expressions in rat. Physiol Res 2011;60:549–558
  • Afzal U, Gulfraz M, Hussain H, et al. Hepatoprotective effects of Justicia adhatoda L. against carbon tetrachloride (CCl4) induced liver injury in Swiss albino mice. Afr J Pharm Pharmacol 2013;7:8–14
  • Yi -Ching Li, Chung-Hsin Yeh, Ming-Ling Yang, Yu-Hsiang Kuan. Luteolin suppresses inflammatory mediator expression by blocking the Akt/NFκB pathway in acute lung injury induced by lipopolysaccharide in Mice. Evid Based Complement Alternat Med 2012;2012:383608
  • Tseng CK, Lin CK, Chang HW, et al. Aqueous extract of Gracilaria tenuistipitata suppresses LPS-Induced NF-kB and MAPK activation in RAW 264.7 and rat peritoneal macrophages and exerts hepatoprotective effects on carbon tetrachloride-treated rat. PLoS ONE 2014;9:e86557
  • Bradham CA, Plumpe J, Manns MP, et al. Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am J Physiol 1998;275:G387–G392
  • Muriel P. Regulation of nitric oxide synthesis in the liver. J Appl Toxicol 2000;20:189–195

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