Fat Intravasation from Intraosseous Flush and Infusion Procedures

References

• Buck ML, Wiggins BS, Sesler JM. Intraosseous drug administration in children and adults during cardiopulmonary resuscitation. Ann Pharmacother. 2007;41:1679–86.
   PubMed Web of Science ®Google Scholar
• Bailey P. Intraosseous infusion. Updated: Sep 24, 2012. www.uptodate.com/contents/intraosseous-infusion
   Google Scholar
• Day MW. Intraosseous devices for intravascular access in adult trauma patients. Crit Care Nurse. 2011;31:76–89; quiz 90.
   PubMed Web of Science ®Google Scholar
• Fowler R, Gallagher JV, Isaacs SM, Ossman E, Pepe P, Wayne M. The role of intraosseous vascular access in the out-of-hospital environment (resource document to NAEMSP position statement). Prehosp Emerg Care. 2007;11:63–6.
   PubMed Web of Science ®Google Scholar
• LaRocco BG, Wang HE. Intraosseous infusion. Prehosp Emerg Care. 2003;7:280–5. Review.
   PubMedGoogle Scholar
• Plewa MC, King RW, Fenn-Buderer N, Gretzinger K, Renuart D, Cruz. Hematologic safety of intraosseous blood transfusion in a swine model of pediatric hemorrhagic hypovolemia. Acad Emerg Med. 1995;2:799–809.
   PubMed Web of Science ®Google Scholar
• Paxton JH. Intraosseous vascular access: a review. Trauma. 2012;14:195–232.
   Google Scholar
• Luck RP, Haines C, Mull CC. Intraosseous access. J Emerg Med. 2010;39:468–75. Epub 2009 Jul 9. Review.
   PubMed Web of Science ®Google Scholar
• Orlowski JP, Porembka DT, Gallagher JM, Lockrem JD, VanLente F. Comparison study of intraosseous, central intravenous, and peripheral intravenous infusions of emergency drugs. Am J Dis Child. 1990;144:112–7.
   PubMedGoogle Scholar
• Voigt J, Waltzman M, Lottenberg L. Intraosseous vascular access for in-hospital emergency use: a systematic clinical review of the literature and analysis. Pediatr Emerg Care. 2012;28:185–99. Review.
   PubMed Web of Science ®Google Scholar
• Phillips L, Brown L, Campbell T, Miller J, Proehl J, Youngberg B. Consortiumn on Intraosseous Vascular Access in Healthcare Practice. Recommendations for the use of intraosseous vascular access for emergent and nonemergent situations in various healthcare settings: a consensus paper. J Emerg Nurs. 2010;36:551–6.
   PubMed Web of Science ®Google Scholar
• Blumberg SM, Gorn M, Crain EF. Intraosseous infusion: a review of methods and novel devices. Pediatr Emerg Care. 2008;24:50–6; quiz 57-8.
   PubMed Web of Science ®Google Scholar
• Miller L, Kramer GC, Bolleter S. Rescue access made easy. JEMS. 2005;30 (suppl): 8–18; quiz suppl 19.
   PubMedGoogle Scholar
• Tobias JD, Ross AK. Intraosseous infusions: a review for the anesthesiologist with a focus on pediatric use. Anesth Analg. 2010;110:391–401. 2009 Nov 6. Review.
   PubMed Web of Science ®Google Scholar
• Vizcarra C, Clum S. Intraosseous route as alternative access for infusion therapy. J Infus Nurs. 2010;33:162–74. Review. Erratum in: J Infus Nurs. 2011;34:123.
   PubMedGoogle Scholar
• Gluckman W, Forti RJ. Intraosseous cannulation. Updated: Jun 13, 2012 from: emedicine.medscape.com/article/908610…
   Google Scholar
• Ngo AS, Oh JJ, Chen Y, Yong D, Ong ME. Intraosseous vascular access in adults using the EZ-IO in an emergency department. Int J Emerg Med. 2009;2:155–60.
   PubMedGoogle Scholar
• Eslami P. Pediatric intraosseous access. Updated: Mar 8, 2013. From: emedicine.medscape.com/article/940993.
   Google Scholar
• Tay ET, Hafeez W. Intraosseous access. Updated: Mar 27, 2013. from: reference.medscape.com/article/80431.
   Google Scholar
• Orlowski JP, Julius CJ, Petras RE, Porembka DT, Gallagher JM. The safety of intraosseous infusions: risks of fat and bone marrow emboli to the lungs. Ann Emerg Med. 1989;18:1062–7.
   PubMed Web of Science ®Google Scholar
• Fiallos M, Kissoon N, Abdelmoneim T, Johnson L, Murphy S, Lu L, Masood S, Idris A. Fat embolism with the use of intraosseous infusion during cardiopulmonary resuscitation. Am J Med Sci. 1997;314:73–9.
   PubMed Web of Science ®Google Scholar
• Byrick RJ. Pulmonary fat embolism and intraosseous infusion. Pediatr Crit Care Med. 2001;2:184–5.
   PubMedGoogle Scholar
• Olaussen A, Williams B. Intraosseous access in the prehospital setting: literature review. Prehosp Disaster Med. 2012;27:468–72. Epub 2012 Aug 9. Review.
   PubMed Web of Science ®Google Scholar
• Weiser G, Hoffmann Y, Galbraith R, Shavit I. Current advances in intraosseous infusion–a systematic review. Resuscitation. 2012;83:20–6. Epub 2011 Aug 24. Review.
   PubMed Web of Science ®Google Scholar
• Myers LA, Russi CS, Arteaga GM. Semiautomatic intraosseous devices inpediatric prehospital care. Prehosp Emerg Care. 2011;15:473–6. Epub 2011 Aug 4.
   PubMed Web of Science ®Google Scholar
• Davidoff J, Fowler R, Gordon D, Klein G, Kovar J, Lozano M, Potkya J, Racht E, Saussy J, Swanson E, Yamada R, Miller L. Clinical evaluation of a novel intraosseous device for adults: prospective, 250-patient, multi-center trial. JEMS. 2005;30 (suppl): 20–23.
   PubMedGoogle Scholar
• Lairet J, Bebarta V, Lairet K, Kacprowicz R, Lawler C, Pitotti R, Bush A, King J. A comparison of proximal tibia, distal femur, and proximal humerus infusion rates using the EZ-IO intraosseous device on the adult swine (Sus scrofa) model. Prehosp Emerg Care. 2013 Apr-Jun;17(2):280–4.
   PubMed Web of Science ®Google Scholar
• Bebarta VS, Vargas TE, Castaneda M, Boudreau S. Evaluation of extremity tissue and bone injury after intraosseous hypertonic saline infusion in proximal tibia and proximal humerus in adult swine. Prehosp Emerg Care. 2014 May 15. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Sontgerath JS, Rubal BJ, DeLorenzo RA, Morgan TL, Ward JA. Variability in intraosseous flush practices by trained emergency physicians. Am J Emerg Med. 2014;32(6):665–9.
   PubMed Web of Science ®Google Scholar
• Rubal BJ, McKay K, Armstrong KR, Rubal MP, Marbach MJ. Variability in intraosseous pressure induced by saline flush of an intraosseous cannula by multiple practitioners. Lab Anim (NY). 2012;41:224–9. Erratum in: Lab Anim (NY). 2012;41:349.
   PubMed Web of Science ®Google Scholar
• Tocantins LM, O'Neill JF. Infusion of blood and other fluids into the general circulation via the bone marrow: technique and results. Surg Gyne Obst. 1941;73:28I.
   Google Scholar
• Tocantins LM, O'Neill JF. Complications of intra-osseous therapy. Ann Surg. 1945; 122:266–77.
   PubMed Web of Science ®Google Scholar
• Akhtar S. Fat embolism. Anesthesiol Clin. 2009;27:533–50.
   PubMedGoogle Scholar
• Jain S, Saigal R, Mittal M, Kansal A, Singh Y, Kolar PR, Jain S. Fat embolism syndrome. J Assoc Physicians India. 2008;56:245–9.
   PubMedGoogle Scholar
• Gupta A, Reilly CS. Fat embolism. Continuing Educ Anaesth Crit Care & Pain. 2007;7:148–51.
   Google Scholar
• Peltier L. The classic fat embolism: an appraisal to the problem. Clin Orthop. 1984;187:3–17.
   PubMedGoogle Scholar
• Hasan MY, Kissoon N, Khan TM, Saldajeno V, Goldstein J, Murphy SP. Intraosseous infusion and pulmonary fat embolism. Pediatr Crit Care Med. 2001;2:133–8.
   PubMedGoogle Scholar
• Möller JC, Tegtmeyer FK, Schaible TF, Sussmane JB. [Intraosseous puncture as vascular access in pediatric emergency and intensive care medicine]. Anaesthesiol Reanim. 1996;21:103–7. German.
   PubMedGoogle Scholar
• Gildenhorn HL, Gildenhorn VB, Amromin G. Marrow embolism and intraosseous contrast radiography. J Am Med Assoc. 1960;173:758–60.
   PubMed Web of Science ®Google Scholar
• Thomas ML, Tighe JR. Death from fat embolism as a complication of intraosseous phlebography. Lancet. 1973;2:1415–6.
   PubMed Web of Science ®Google Scholar
• Young AE, Evans IL, Irving D, Hanning CD. Fat embolism after pertrochanteric venography. Br Med J. 1973;4:592.
   PubMed Web of Science ®Google Scholar
• Denman FR, Gragg L. Fat embolism; a diagnostic enigma. Arch Surg. 1948;57:325–32.
   PubMed Web of Science ®Google Scholar
• Gupta B, D'souza N, Sawhney C, Farooque K, Kumar A, Agrawal P, Misra MC. Analyzing fat embolism syndrome in trauma patients at AIIMS Apex Trauma Center, New Delhi, India. J Emerg Trauma Shock. 2011 Jul;4:337–41.
   PubMedGoogle Scholar
• Husebye EE, Lyberg T, Røise O. Bone marrow fat in the circulation: clinical entities and pathophysiological mechanisms. Injury. 2006;37 (Suppl 4):S8–S18. Review. Erratum in: Injury. 2007;38:1224.
   PubMed Web of Science ®Google Scholar
• Mellor A, Soni N. Fat embolism. Anaesthesia. 2001;56:145–54. Review.
   PubMed Web of Science ®Google Scholar
• Ereth MH, Weber JG, Abel MD, Lennon RL, Lewallen DG, Ilstrup DM, Rehder K. Cemented versus noncemented total hip arthroplasty: embolism, hemodynamics, and intrapulmonary shunting. Mayo Clin Proc. 1992;67:1066–74.
   PubMed Web of Science ®Google Scholar
• Pitto RP, Hamer H, Faiani R, Radespiel-Troeger M, Koessler M. Prophylaxis against fat and bone-marrow embolism during total hip arthroplasty reduces the incidence of postoperative deep-vein thrombosis. J Bone Joint Surg [Am] 2002;84-A:39–48.
   PubMedGoogle Scholar
• Koessler MJ, Fabiani R, Hamer H, Pitto RP. The clinical relevance of embolic events detected by transesophageal echocardiography during cemented total hip arthroplasty: a randomized clinical trial. Anesth Analg. 2001;92:49–55.
   PubMed Web of Science ®Google Scholar
• Herndon JH, Bechtol CO, Crickenberger DP. Fat embolism during total hip replacement: a prospective study. J Bone Joint Surg Am. 1974;56:1350–62.
   PubMed Web of Science ®Google Scholar
• Colombo JL, Hallberg TK. Recurrent aspiration in children: lipid laden alveolar macrophage quantitation. Pediatr Pulmonol. 1987;3:86–9.
   PubMed Web of Science ®Google Scholar
• Froehlich JA, Dorfman GS, Cronan JJ, Urbanek PJ, Herndon JH, Aaron RK. Compression ultrasonography for the detection of deep venous thrombosis in patients who have a fracture of the hip: a prospective study. J Bone Joint Surg Am. 1989;71:249–56.
   PubMedGoogle Scholar
• Wile UJ, Schamberg IL. Pulmonary embolism following infusion via the bone marrow. J Invest Dermatol. 1942;5:173–7.
   Google Scholar
• Heinild S, Sondergaard T, Tudvad F. Bone marrow infusion in childhood: experiences from a thousand infusions. J Pediatr. 1947;30:400–12.
   PubMed Web of Science ®Google Scholar
• Johnson AS, Bolte RG. Pulmonary embolism in the pediatric patient. [Review] [55 refs] Pediatr Emerg Care. 2004;20:555–60; quiz 561-3.
   PubMed Web of Science ®Google Scholar
• Stein PD, Yaekoub AY, Matta F, Kleerekoper M. Fat embolism syndrome. Am J Med Sci. 2008;336:472–7.
   PubMed Web of Science ®Google Scholar
• Eriksson EA, Pellegrini DC, Vanderkolk WE, Minshall CT, Fakhry SM, Cohle SD. Incidence of pulmonary fat embolism at autopsy: an undiagnosed epidemic. J Trauma. 2011;71:312–5.
   PubMed Web of Science ®Google Scholar
• Krischner JP, Fine EG, Davis JH, Nagel EL. Complications of cardiac resuscitation. Chest. 1987;92:287–91.
   PubMed Web of Science ®Google Scholar
• Lairet J, Bebarta V, Shaw J, Kuschnerait L, Lawler C, Boudreau S, Vargas T, King J. Comparison of intraosseous infusion rates of plasma under high pressure in an adult hypovolemic swine model in two different limb sites. Acad Emerg Med. 20(5):S13 (abstract).
   Google Scholar
• Lairet JR, Bebarta V, Mathis D, Warren W, Lawler C, Lairet K, Muncy T, Boudreau S, Pitotti R, Brock J, King J. Comparison of intraosseous infusion rates of blood under high pressure in and adult hypovolemic swine model in three different limb sites. Ann Emerg Med. 2012:60(4S):S75 (abstract).
   Google Scholar
• Marshall PD, Douglas DL, Henry L. Fatal pulmonary fat embolism during total hip replacement due to high-pressure cementing techniques in an osteoporotic femur. Br J Clin Pract. 1991;45:148–9.
   PubMedGoogle Scholar
• Shaikh N. Emergency management of fat embolism syndrome. J Emerg Trauma Shock. 2009;2:29–33.
   PubMedGoogle Scholar
• Weinhouse GL. Fat embolism syndrome. Updated: Apr 23, 2012 from: www.uptodate.com/contents/fat-embolism-syndrome…
   Google Scholar
• Joynt GM, Li TST, Wai JKM, Yap FHY. Fat embolism syndrome. Crit Care Shock. 2008;11:83–93.
   Google Scholar
• Young AE, Thomas ML, Browse NL. Intraosseous phlebography and fat embolism. Br Med J. 1976;2:89–90.
   PubMed Web of Science ®Google Scholar
• Wenda K, Runkel M, Degreif J, Ritter G. Pathogenesis and clinical relevance of bone marrow embolism in medullary nailing –demonstrated by intraoperative echocardiography. Injury. 1993;24 (Suppl 3):S73–S81.
   PubMed Web of Science ®Google Scholar
• Stokes GG. On the theories of the internal friction of fluids in motion, and of the equilibrium and motion of elastic solids. Trans Cambridge Philos Soc. 1849; 8:287–319.
   Google Scholar
• Wenda K, Ritter G, Ahlers, von Issendorff WD. Nachweis und Effekte von Knochenmarkeinschwemmungen bei Operationen im Bereich der Femurmarkhohle. Unfallchirurg. 1990;93:56–61.
   PubMed Web of Science ®Google Scholar
• Hofmann S, Huemer G, Kratochwill C, Koller-Strametz J, Hopf R, Schlag G, Salzer M. [Pathophysiology of fat embolisms in orthopedics and traumatology]. Orthopade. 1995;24:84–93. Review. German.
   PubMedGoogle Scholar
• Blankstein M, Byrick RJ, Nakane M, Bang AK, Freedman J, Garvey MB, Zdero R, Schemitsch EH. A preliminary study of platelet activation after embolization of marrow contents. J Orthop Trauma. 2012;26:e214–20.
   PubMed Web of Science ®Google Scholar
• Globule size distribution in lipid injectable emulsions (USP 729). In 2009 U.S. Pharmacopeial Convention: USP32–NF27, p. 283. Pharmacopeial Forum. 34(2): 341.
   Google Scholar