References
- Centers for Disease Control and Prevention. Leading Causes of Death. Atlanta, GA: Author; 2010. Available at: http://www.cdc.gov/injury/wisqars/LeadingCauses.html.
- Norton R, Kobusingye O. Injuries. N Engl J Med 2013;368(18):1723–30.
- Cap AP, Baer DG, Orman JA, Aden J, Ryan K, Blackbourne LH. Tranexamic acid for trauma patients: a critical review of the literature. J Trauma 2011;71(1 Suppl):S9–14.
- Brohi K, Cohen MJ, Davenport RA. Acute coagulopathy of trauma: mechanism, identification and effect. Curr Opin Crit Care 2007;13(6):680–5.
- Sperry JL, Ochoa JB, Gunn SR Inflammation the host response to injury I. an FFP:PRBC transfusion ratio >/ = 1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma 2008;65(5):986–93.
- Hauser CJ, Boffard K, Dutton R,…Group CS. Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage. J Trauma 2010;69(3):489–500.
- Gando S, Tedo I, Kubota M. Posttrauma coagulation and fibrinolysis. Crit Care Med 1992;20(5):594–600.
- Chapman MP, Moore EE, Moore HB Overwhelming tPA release, not PAI-1 degradation, is responsible for hyperfibrinolysis in severely injured trauma patients. J Trauma Acute Care Surg 2015. 2016 Jan;80(1):16–25.
- Porta CR, Nelson D, McVay D The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis. J Trauma Acute Care Surg 2013;75(6):954–60.
- Crash Trial Collaborators, Shakur H, Roberts I Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010;376(9734):23–32.
- Morrison JJ, Dubose JJ, Rasmussen TE, Midwinter MJ. Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study. Arch Surg 2012;147(2):113–9.
- Services OEM. Notice of changes to trauma triage rules: (OAC 4765-14). Columbus, OH: Ohio Department of Public Safety; 2008. Available at: http://www.publicsafety.ohio.gov/links/ems_oac4765_14_geriatric_triage_details09.pdf
- Mayo Clinic. Helicopter - Mayo One. Available at: http://www.mayoclinic.org/helicoptermdashmayoone/art-20057597.
- Brown JB, Neal MD, Guyette FX Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: addressing the knowledge gaps. Prehosp Emerg Care 2015;19(1):79–86.
- Crash Trial collaborators, Roberts I, Shakur H The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet 2011;377(9771):1096–101, 1101 e1091–92.
- Toner RW, Pizzi L, Leas B, Ballas SK, Quigley A, Goldfarb NI. Costs to hospitals of acquiring and processing blood in the US: a survey of hospital-based blood banks and transfusion services. Appl Health Econ Health Policy 2011;9(1):29–37.
- Guerriero C, Cairns J, Perel P, Shakur H, Roberts I, Crash Trial Collaborators. Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial. PLoS One 2011;6(5):e18987.
- World Health Organization. Tranexamic acid (Inclusion), 2015. Available at: http://www.who.int/selection_medicines/committees/expert/17/application/tranexamic/en/
- Dewan Y, Komolafe EO, Mejia-Mantilla JH, …Crash Trial Collaborators. CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial. Trials 2012;13:87.
- Hoogmartens O, Heselmans A, Van de Velde S Evidence-based prehospital management of severe traumatic brain injury: a comparative analysis of current clinical practice guidelines. Prehosp Emerg Care 2014;18(2):265–73.