Autoantibodies against aminoacyl-tRNA synthetase: novel diagnostic marker for type 1 diabetes mellitus

References

• Adam AC, Grohe C, Stier S, Gattenlohner S, Balta Z, Buttner R, Gutgemann I. (2007). Hodgkin’s lymphoma in a patient with Jo-1 syndrome. Virchows Arch 451:101–4.
   Google Scholar
• Alleva DG, Gaur A, Jin L, Wegmann D, Gottlieb PA, Johnson EB, Motheral T, Putnam A, Crowe PD, Ling N, Boehme SA, Conlon PJ. (2002). Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide. Diabetes 51:2126–34.
   PubMed Web of Science ®Google Scholar
• Antonellis A, Ellsworth RE, Sambuughin N, Puls I, Abel A, Lee SQ, Jordanova A, Kremensky I, Christodoulou K, Middleton LT, Sivakumar K, Ionasescu V, Funalot B, Vance JM, Goldfarb LG, Fischbeck KH, Green ED. (2003). Glycyl tRNA synthetase mutations in Charcot–Marie–Tooth disease type 2D and distal spinal muscular atrophy type V. Am J Hum Genet 72:1293–9.
   PubMed Web of Science ®Google Scholar
• Bilbao JR, Rica I, Vazquez JA, Busturia MA, Castano L. (2000). Influence of sex and age at onset on autoantibodies against insulin, GAD65 and IA2 in recent onset type 1 diabetic patients. Horm Res 54:181–5.
   PubMedGoogle Scholar
• Boasso A, herbeuval JP, Hardy AW, Winkler C, Shearer GM. (2005). Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-Fc in human CD4+ T cells. Blood 105:1574–81.
   PubMed Web of Science ®Google Scholar
• Bougneres PF, Landais P, Boisson C, Carel JC, Frament N, Boitard C, Chaussain JL, Bach JF. (1990). Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin. Diabetes 39:1264–72.
   PubMed Web of Science ®Google Scholar
• Casares S, Hurtado A, Mcevoy RC, Sarukhan A, Von Boehmer H, Brumeanu TD. (2002). Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide-MHC class II chimera. Nat Immunol 3:383–91.
   PubMed Web of Science ®Google Scholar
• Dyck PJ, Lambert EH. (1968). Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. II. Neurologic, genetic, and electrophysiologic findings in various neuronal degenerations. Arch Neurol 18:619–25.
   PubMedGoogle Scholar
• Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the diagnosis and classification of diabetes mellitus. (2003). Diabetes Care 26 (Suppl. 1):S5–20.
   Google Scholar
• Favorova OO, Zargarova TA, Rukosuyev VS, Beresten SF, Kisselev LL. (1989). Molecular and cellular studies of tryptophanyl-tRNA synthetases using monoclonal antibodies. Remarkable variations in the content of tryptophanyl-tRNA synthetase in the pancreas of different mammals. Eur J Biochem 184:583–8.
   Google Scholar
• Hirakata M, Suwa A, Takeda Y, Matsuoka Y, Irimajiri S, Targoff IN, Hardin JA, Craft J. (1996). Autoantibodies to glycyl-transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity. Arthritis Rheumatism 39:146–51.
   PubMedGoogle Scholar
• Howard OM, Dong HF, Yang D, Raben N, Nagaraju K, Rosen A, Casciol-Rosen L, Hartlein M, Kron M, Yang D, Yiadom K, Dwivedi S, Plotz PH, Oppenheim JJ. (2002). Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. J Exp Med 196:781–91.
   PubMed Web of Science ®Google Scholar
• Jordanova A, Irobi J, Thomas FP, Van Dijck P, Meerschaert K, Dewil M, Dierick I, Jacobs A, De Vriendt E, Guergueltcheva V, Rao CV, Tournev I, Gondim FA, D’hooghe M, Van Gerwen V, Callaerts P, Van Den Bosch L, Timmermans JP, Robberecht W, Gettemans J, Thevelein JM, De Jonghe P, Kremensky I, Timmerman V. (2006). Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot–Marie–Tooth neuropathy. Nat Genet 38:197–202.
   PubMed Web of Science ®Google Scholar
• Kaminska M, Shalak V, Francin M, Mirande M. (2007). Viral hijacking of mitochondrial lysyl-tRNA synthetase. J Virol 81:68–73.
   Google Scholar
• Kantarova D, Buc M. (2007). Genetic susceptibility to type 1 diabetes mellitus in humans. Physiol Res 56:255–66.
   PubMed Web of Science ®Google Scholar
• Kawasaki E, Matsuura N, Eguchi K. (2006). Type 1 diabetes in Japan. Diabetologia 49:828–36.
   PubMed Web of Science ®Google Scholar
• Kisselev LL, Justesen J, Wolfson AD, Frolova LY. (1998). Diadenosine oligophosphates (Ap(n)A), a novel class of signalling molecules? FEBS Lett 427:157–63.
   PubMedGoogle Scholar
• Knip M, Siljander H. (2008). Autoimmune mechanisms in type 1 diabetes. Autoimmun Rev 7:550–7.
   PubMed Web of Science ®Google Scholar
• Koreeda Y, Higashimoto I, Yamamoto M, Takahashi M, Kaji K, Fujimoto M, Kuwana M, Fukuda Y. (2010). Clinical and pathological findings of interstitial lung disease patients with anti-aminoacyl-tRNA synthetase autoantibodies. Int Med 49:361–9.
   PubMed Web of Science ®Google Scholar
• Ko YG, Kim EY, Kim T, Park H, Park HS, Choi EJ, Kim S. (2001). Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. J Biol Chem 276:6030–6.
   PubMed Web of Science ®Google Scholar
• Kovaleski BJ, Kennedy R, Hong MK, Datta SA, Kleiman L, Rein A, Musier-Forsyth K. (2006). In vitro characterization of the interaction between HIV-1 Gag and human lysyl-tRNA synthetase. J Biol Chem 281:19449–56.
   PubMed Web of Science ®Google Scholar
• Kron MA, Petridis M, Haertlein M, Libranda-Ramirez B, Scaffidi LE. (2005). Do tissue levels of autoantigenic aminoacyl-tRNA synthetase predict clinical disease? Med Hypoth 65:1124–7.
   Google Scholar
• Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Sundberg JP, Schimmel P, Ackerman SL. (2006). Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature 443:50–5.
   PubMed Web of Science ®Google Scholar
• Mathews MB, Bernstein RM. (1983). Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity. Nature 304:177–9.
   PubMed Web of Science ®Google Scholar
• Mauricio D, De Leiva A. (2001). Autoimmune gestational diabetes mellitus:a distinct clinical entity? Diabet Metab Res Rev 17:422–8.
   PubMed Web of Science ®Google Scholar
• Nangle LA, Motta CM, Schimmel P. (2006). Global effects of mistranslation from an editing defect in mammalian cells. Chem Biol 13:1091–100.
   PubMedGoogle Scholar
• Nangle LA, Zhang W, Xie W, Yang XL, Schimmel P. (2007). Charcot–Marie–Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect. Proc Nat Acad Sci USA 104:11239–44.
   PubMed Web of Science ®Google Scholar
• Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D. (2006). Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science 311:1775–8.
   PubMed Web of Science ®Google Scholar
• Park SG, Ewalt KL, Kim S. (2005a). Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers. Trends Biochem Sci 30:569–74.
   PubMed Web of Science ®Google Scholar
• Park SG, Kang YS, Kim JY, Lee CS, Ko YG, Lee WJ, Lee KU, Yeom YI, Kim S. (2006). Hormonal activity of AIMP1/p43 for glucose homeostasis. Proc Nat Acad Sci USA 103:14913–18.
   PubMed Web of Science ®Google Scholar
• Park SG, Kim HJ, Min YH, Choi EC, Shin YK, Park BJ, Lee SW, Kim S. (2005b). Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. Proc Nat Acad Sci USA 102:6356–61.
   PubMed Web of Science ®Google Scholar
• Park Y, Lee H, Koh CS, Min H, Rowley M, Mackay IR, Zimmet P, Mccarthy B, Mccanlies E, Dorman J, Trucco M. (1996). The low prevalence of immunogenetic markers in Korean adult-onset IDDM patients. Diabetes Care 19:241–5.
   Google Scholar
• Riley WJ. (1992). Autoimmune polyglandular syndromes. Horm Res 38:9–15.
   Google Scholar
• Sakumai M, Yachie A, Kasahara Y. (2007). [Role of T cells in the pathogenesis of type I diabetes mellitus: structure analysis of complementarity determining region 3 of circulating T cells]. Rinsho Byori 55:112–19.
   Google Scholar
• Scheinker VS, Beresten SF, Mazo AM, Ambartsumyan NS, Rokhlin OV, Favorova OO, Kisselev LL. (1979). Immunochemical studies of beef pancreas tryptophanyl-tRNA synthetase and its fragments. Determination of the number of antigenic determinants and a comparison with tryptophanyl-tRNA synthetases from other sources and with reverse transcriptase from avian myeloblastosis virus. Eur J Biochem 97:529–40.
   Google Scholar
• Scheper GC, Van Der Klok T, Van Andel RJ, Van Berkel CG, Sissler M, Smet J, Muravina TI, Serkov SV, Uziel G, Bugiani M, Schiffmann R, Krageloh-Mann I, Smeitink JA, Florentz C, Van Coster R, Pronk JC, Van Der Knaap MS. (2007). Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation. Nat Genet 39:534–9.
   PubMed Web of Science ®Google Scholar
• Taplin CE, Barker JM. (2008). Autoantibodies in type 1 diabetes. Autoimmunity 41:11–18.
   PubMed Web of Science ®Google Scholar
• Tisch R, Liblau RS, Yang XD, Liblau P, Mcdevitt HO. (1998). Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice. Diabetes 47:894–9.
   PubMed Web of Science ®Google Scholar
• Tzima E, Reader JS, Irani-Tehrani M, Ewalt KL, Schwartz MA, Schimmel P. (2005). VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function. J Biol Chem 280:2405–8.
   Google Scholar
• Wakasugi K, Slike BM, Hood J, Otani A, Ewalt KL, Friedlander M, Cheresh DA, Schimmel P. (2002). A human aminoacyl-tRNA synthetase as a regulator of angiogenesis. Proc Nat Acad Sci USA 99:173–7.
   PubMed Web of Science ®Google Scholar
• Wenzlau JM, Juhl K, Yu L, Moua O, Sarkar SA, Gottlieb P, Rewers M, Eisenbarth GS, Jensen J, Davidson HW, Hutton JC. (2007). The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Nat Acad Sci USA 104:17040–5.
   PubMed Web of Science ®Google Scholar
• Yoshifuji H, Fujii T, Kobayashi S, Imura Y, Fujita Y, Kawabata D, Usui T, Tanaka M, Nagai S, Umehara H, Mimori T. (2006). Anti-aminoacyl-tRNA synthetase antibodies in clinical course prediction of interstitial lung disease complicated with idiopathic inflammatory myopathies. Autoimmunity 39:233–41.
   PubMed Web of Science ®Google Scholar