Clinical and metabolic effects of drospirenone–estradiol in menopausal women: a prospective study

References

• Peltonen M, Lundberg V, Huhtasaari F, Asplund K. Marked improvement in survival after acute myocardial infarction in middle-aged men but not in women. The Northern Sweden MONICA study 1985–94. J Intern Med 2000;247:579–87
   PubMed Web of Science ®Google Scholar
• Mosca L, Appel LJ, Benjamin EJ, e tal. Summary of the American Heart Association's evidence-based guidelines for cardiovascular disease prevention in women. Arterioscler Thromb Vasc Biol 2004;24:394–6
   PubMed Web of Science ®Google Scholar
• Board of the International Menopause Society, Pines A, Sturdee DW, Birkhäuser MH, e tal. IMS updated recommendations on postmenopausal hormone therapy. Climacteric 2007;10:181–94
   PubMed Web of Science ®Google Scholar
• Grodstein F, Stampfer MJ, Colditz GA, e tal. Postmenopausal hormone therapy and mortality. N Engl J Med 1997;336:1769–75
   PubMed Web of Science ®Google Scholar
• Rossouw JE, Anderson GL, Prentice RL, e tal. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. J Am Med Assoc 2002;288:321–33
   PubMed Web of Science ®Google Scholar
• Rossouw JE, Prentice RL, Manson JE, e tal. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. J Am Med Assoc 2007;297:1465–77
   PubMed Web of Science ®Google Scholar
• Collins P, Rosano G, Casey C, e tal. Management of cardiovascular risk in the perimenopausal women: a consensus statement of European cardiologists and gynecologists. Climacteric 2007;10:508–26
   PubMed Web of Science ®Google Scholar
• Grodstein F, Manson JE, Stampfer MJ. Hormone therapy and coronary heart disease: the role of time since menopause and age at hormone initiation. J Womens Health (Larchmt) 2006;15:35–44
   PubMed Web of Science ®Google Scholar
• Salpeter SR, Walsh JM, Greyber E, Ormiston TM, Salpeter EE. Mortality associated with hormone replacement therapy in younger and older women: a meta-analysis. J Gen Intern Med 2004;19:791–804
   PubMed Web of Science ®Google Scholar
• Oelkers W. Drospirenone – a new progestogen with antimineralocorticoid activity, resembling natural progesterone. Eur J Contracept Reprod Health Care 2000;5(Suppl 3):17–24
   PubMedGoogle Scholar
• Krattenmacher R. Drospirenone: pharmacology and pharmacokinetics of a unique progestogen. Contraception 2000;62:29–38
   PubMed Web of Science ®Google Scholar
• Schürmann R, Holler T, Benda N. Estradiol and drospirenone for climacteric symptoms in postmenopausal women: a double-blind, randomized, placebo-controlled study of the safety and efficacy of three dose regimens. Climacteric 2004;7:189–96
   PubMed Web of Science ®Google Scholar
• Archer DF, Thorneycroft IH, Foegh M, e tal. Long-term safety of drospirenone–estradiol for hormone therapy: a randomized, double-blind, multicenter trial. Menopause 2005;12:716–27
   PubMed Web of Science ®Google Scholar
• Warming L, Ravn P, Nielsen T, Christiansen C. Safety and efficacy of drospirenone used in a continuous combination with 17beta-estradiol for prevention of postmenopausal osteoporosis. Climacteric 2004;7:103–11
   PubMed Web of Science ®Google Scholar
• Preston RA, White WB, Pitt B, Bakris G, Norris PM, Hanes V. Effects of drospirenone/17-beta estradiol on blood pressure and potassium balance in hypertensive postmenopausal women. Am J Hypertens 2005;18:797–804
   PubMed Web of Science ®Google Scholar
• White WB, Pitt B, Preston RA, Hanes V. Antihypertensive effects of drospirenone with 17beta-estradiol, a novel hormone treatment in postmenopausal women with stage 1 hypertension. Circulation 2005;112:1979–84
   PubMed Web of Science ®Google Scholar
• Rapkin AJ, Sorger SN, Winer SA. Drospirenone/ethinyl estradiol. Drugs Today 2008;44:133–45
   PubMed Web of Science ®Google Scholar
• Hunter M. The Women's Health Questionnaire: a measure of mid-aged women's perceptions of their emotional and physical health. Psychol Health 1992;7:45–54
   Web of Science ®Google Scholar
• Hunter M. The Women's Health Questionnaire (WHQ): the development, standardization and application of a measure of mid-aged women's emotional and physical health. Qual Life Res 2000;9:733–8
   Web of Science ®Google Scholar
• Genazzani AR, Nicolucci A, Campagnoli C, et al., for the Progetto Donna Qualità della Vita Working Group; Novo Nordisk Italia. Validation of Italian version of the Women's Health Questionnaire: assessment of quality of life of women from the general population and those attending menopause centers. Climacteric 2002;5:70–7
   PubMed Web of Science ®Google Scholar
• Gambacciani M, Ciaponi M, Cappagli B, e tal. Effects of low-dose, continuous combined estradiol and noretisterone acetate on menopausal quality of life in early postmenopausal women. Maturitas 2003;44:157–63
   PubMed Web of Science ®Google Scholar
• Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412–19
   PubMed Web of Science ®Google Scholar
• Casanova G, Radavelli S, Lhullier F, Spritzer PM. Effects of nonoral estradiol-micronized progesterone or low-dose oral estradiol-drospirenone therapy on metabolic variables and markers of endothelial function in early postmenopause. Fertil Steril 2009;92:605–12
   PubMed Web of Science ®Google Scholar
• Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005;365:217–23
   PubMed Web of Science ®Google Scholar
• Mancia G, De Backer G, Dominiczak A, e tal. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007;28:1462–536
   PubMed Web of Science ®Google Scholar
• Cho GJ, Lee JH, Park HT, e tal. Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome. Menopause 2008;15: 524–9
   PubMed Web of Science ®Google Scholar
• Genazzani AR, Gambacciani M, Simoncini T, Schneider HP; International Menopause Society. HRT in climacteric and aging brain. Climacteric 2003;6:188–203
   PubMed Web of Science ®Google Scholar
• Freedman RR. Physiology of hot flashes. Am J Hum Biol 2001;13:453–64
   PubMed Web of Science ®Google Scholar
• Gerber LM, Sievert LL, Warren K, Pickering TG, Schwartz JE. Hot flashes are associated with increased ambulatory systolic blood pressure. Menopause 2007;14:308–15
   PubMed Web of Science ®Google Scholar
• Gambacciani M, Ciaponi M, Cappagli B, Benussi B, De Simone L, Genazzani AR. Climacteric modifications in body weight and fat tissue distribution. Climacteric 1999;2:37–44
   PubMedGoogle Scholar
• Amigoni S, Morelli P, Parazzini F, Chatenoud L. Determinants of elevated blood pressure in women around menopause: results from a cross-sectional study in Italy. Maturitas 2000;34:25–32
   PubMed Web of Science ®Google Scholar