References
- Kessler RC, McGonagle KA, Nelson CB, Hughes M, Swartz M, Blazer DG. Sex and depression in the National Comorbidity Survey. II. Cohort effects. J Affect Disorders 1994;30:15–26
- Kessler RC, Berglund P, Demler O, . The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003;289:3095–105
- Weissman MM, Olfson M. Depression in women: implications for health care research Science 1995;269:799–801
- McKnight-Eily LR, Presley-Cantrell L, Elam-Evans LD, Chapman DP, Kaslow NJ, Perry GS. Prevalence and correlates of current depressive symptomatology and lifetime diagnosis of depression in black women. Women's Health Issues 2009;19:243–52
- Weissman MM, Bland RC, Canino GJ, . Cross-national epidemiology of major depression and bipolar disorder. JAMA 1996;276:293–9
- Kessler RC, McGonagle KA, Swartz M, Blazer DB, Nelson CB. Sex and depression in the National Comorbidity Survey. I. Lifetime prevalence,chronicity and recurrence. J Affect Disorders 1993;29:85–96
- Laumann E, Paik A, Rosen RC. Sexual dysfunction in the United States:prevalence and predictors. JAMA 1999;281:537–44
- Basson R. Sexual sequelae of general medical disorders. Lancet 2007;369:409–24
- Kennedy SH, Dickens SE, Eisfeld BS, Bagby RM. Sexual dysfunction before antidepressant therapy in major depression. J Affect Disord 1999;56:201–8
- Williams VS, Baldwin DS, Hogue SL, Fehnel SE, Hollis KA, Edin HM. Estimating the prevalence and impact of antidepressant-induced sexual dysfunction in two European countries: a cross-sectional patient survey. J Clin Psychiatry 2006;67: 204–10
- Montejo AL, Llorca G, Izquierdo JA, Rico-Villademoros F. Incidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction. J Clin Psychiatry 2001;62(Suppl 3):10–21
- Werneke U, Northey S, Bhugra D. Antidepressants and sexual dysfunction. Acta Psychiatr Scand 2006;114:384–97
- Schweitzer I, Maguire K, Ng C. Sexual side-effects of contemporary antidepressants: review. Aust NZ J Psychiatry 2009;43: 795–808
- Williams DR, Gonzalez HM, Neighbors H, . Prevalence and distribution of major depressive disorder in African Americans, Caribbean Blacks, and Non-Hispanic whites: results from the National Survey of American life. Arch Gen Psychiatry 2007;64:305–15
- Strine TW, Koroenke K, Dhingra S, . The association between depression health-related quality of life, social support, life satisfaction, and disability in community-dwelling US adults. J Nervous Mental Dis 2008;197:61–4
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorder. Washington, DC: American Psychiatric Association, 2000
- Byles J, Loxton D, Berecki J, . Use and costs of medications and other health care resources: Findings from the Australian Longitudinal Study on Women's Health. University of Newcastle and the University of Queensland: Women's Health Australia, 2008
- Murrell SA, Himmelfarb S, Wright K. Prevalence of depression and its correlates in older adults. Am J Epidemiol 1983;117: 173–85
- Ustun T, Ayuso Mateos J, Chatterji S, Matthers C, Murracy C. Global burden of depressive disorders in the year 2000. Br J Psychiatry 2004;184:386–92
- Murray J, Lopez A, eds. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries and Risk Factors in 1990 and Projected to 2020. Summary. Boston: Harvard School of Public Health, 1996
- Irwin MR, Miller AH. Depressive disorders and immunity: 20 years of progress and discovery. Brain Behav Immun 2007;21:374–83
- Judd L. Mood disorders in the general population represent an important and worldwide public health problem. Int Clin Psychopharmacol 1995;10(Suppl 4):5–10
- Cuijpers P, Smit F. Subthreshold depression as a risk indicator for major depressive disorder: a systematic review of prospective studies. Acta Psychiatr Scand 2004;109:325–31
- Patten SB, Wang JL, Williams JVA, . Descriptive epidemiology of major depression in Canada. Can J Psychiatry 2006;51: 84–90
- Noble RE. Depression in women. Metabolism 2005;54(Suppl 1):49–52
- Holsboer F, Lauer CJ, Schreiber W, Krieg JC. Altered hypothalamic-pituitary-adrenocortical regulation in healthy subjects at high familial risk for affective disorders. Neuroendocrinology 1995;62:340–7
- Yehuda R, Golier JA, Kaufman S. Circadian rhythm of salivary cortisol in Holocaust survivors with and without PTSD. Am J Psychiatry 2005;162:998–1000
- Carroll BJ, Curtis GC, Mendels J. Neuroendocrine regulation in depression. II. Discrimination of depressed from nondepressed patients. Arch Gen Psychiatry 1976;33:1051–8
- Stetler C, Miller GE. Depression and hypothalamic-pituitary-adrenal activation: a quantitative summary of four decades of research. Psychosom Med 2011;73:114–26
- Lehnert H, Schulz C, Dieterich K. Physiological and neurochemical aspects of corticotropin-releasing factor actions in the brain: the role of the locus coeruleus. Neurochem Res 1998;23:1039–52
- Florian H. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 2000;23:477–501
- Accortt EE, Freeman MP, Allen JJ. Women and major depressive disorder: clinical perspectives on causal pathways. J Women's Health 2008;17:1583–90
- Alexander JL, Dennerstein L, Fugate Woods N, . Neurobehavioral impact of menopause on mood. Exp Rev Neurotherapeutics 2007;7(11 Suppl):S81–91
- Clayton AH, Ninan PT. Depression or menopause? Presentation and management of major depressive disorder in perimenopausal and postmenopausal women. Prim Care Companion J Clin Psychiatry 2010;12:e1–13
- Freeman EW, Sammel MD, Lin H, . Symptoms associated with menopausal transition and reproductive hormones in midlife women. Obstet Gynecol 2007;110:230–40
- Freeman EW. Associations of depression with the transition to menopause. Menopause 2010;17:823–7
- Dennerstein L, Soares CL. The unique challenges of managing depression in mid-life women. World Psychiatry 2008;7: 137–42
- Harlow BL, Wise LA, Otto MW, Soares CN, Cohen LS. Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: The Harvard Study of Moods and Cycles. Arch Gen Psychiatry 2003;60: 29–36
- Rasgon N, Shelton S, Halbreich U. Perimenopausal mental disorders:epidemiology and phenomenology. CNS Spectrums 2005;10:471–8
- Freeman EW, Sammel MD, Lin H, Nelson DB. Associations of hormones and menopausal status with depressed mood in women with no history of depression. Arch Gen Psychiatry 2006;63:375–82
- Gallicchio L, Schilling C, Miller SR, Zacur H, Flaws JA. Correlates of depressive symptoms among women undergoing the menopausal transition. J Psychosom Res 2007;63:263–8
- Woods NF, Smith-DiJulio K, Percival DB, Tao EY, Mariella A, Mitchell ES. Depressed mood during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study. Menopause 2008;15:223–32
- Woods NF, Smith-Dijulio K, Percival DB, Tao EY, Taylor HJ, Mitchell ES. Symptoms during the menopausal transition and early postmenopause and their relation to endocrine levels over time: observations from the Seattle Midlife Women's Health Study. J Womens Health (Larchmt) 2007;16:667–77
- Santoro N, Torrens J, Crawford S, . Correlates of circulating androgens in mid-life women: the Study of Women's Health Across the Nation. J Clin Endocrinol Metab 2005;90: 4836–45
- Roberts CGP, Ladenson PW. Hypothyroidism. Lancet 2004;363:793–803
- Fountoulakis KN, Kantartzis S, Siamouli M, . Peripheral thyroid dysfunction in depression. World J Biol Psychiatry 2006;7:131–7
- Rapkin A, Mikacich J, Moatakef-Imani B, Rasgon N. The clinical nature and formal diagnosis of premenstrual, postpartum, and perimenopausal affective disorders. Curr Psychiatry Rep 2002;4:419–28
- Schmidt P, Rubinow D. Menopause-related affective disorders: a justification for further study. Am J Psychiatry 1991;148: 844–52
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Washington, DC: American Psychiatric Press, 1994
- Stahl SM. The psychopharmacology of sex. Neurotransmitters and the 3 phases of the human sexual response. J Clin Psychiatry 2001;62:80–1
- Johannes CB, Clayton AH, Odom DM, . Distressing sexual problems in United States women revised: prevalence after accounting for depression. J Clin Psychaitry 2009;70: 1698–706
- Laurent SM, Simons AD. Sexual dysfunction in depression and anxiety: conceptualizing sexual dysfunction as part of an internalizing dimension. Clin Psychol Rev 2009;29:573–85
- Bartlik B, Kocsis J, Legere R, Villaluz J, Kossoy A, Gelenburg A. Sexual dysfunction secondary to depressive disorders. J Gend Specif Med 1999;2:52–60
- Shifren JL, Monz BU, Russo PA, Segreti A, Johannes CB. Sexual problems and distress in United States women: prevalence and correlates. Obstet Gynecol 2008;112:970–8
- Dennerstein L, Guthrie JR, Hayes RD, DeRogatis LR, Lehert P. Sexual Function, dysfunction, and sexual distress in a prospective, population-based sample of mid-aged, Australian-born women. J Sex Med 2008;5:2291–9
- Martin-Merino E, Ruigomez A, Johansson S, Wallander MA, Garcia-Rodriguez LA. Study of a cohort of patients newly diagnosed with depression in general practice: prevalence, incidence, comorbidity, and treatment patterns. Prim Care Companion J Clin Psychiatry 2010;12:PCC 08m00764
- Thacker HL. Assessing risks and benefits of nonhormonal treatments for vasomotor symptoms in perimenopausal and postmenopausal women. J Womens Health (Larchmt) 2011;20: 1007–16
- Sjoerdsma T, Palfregman A. A history of serotonin. Ann NY Acad Sci 1990;600:2–9
- Vaswani M, Linda FK, Ramesh S. Role of selective serotonin reuptake inhibitors in psychiatric disorders: a comprehensive review. Prog Neuropsychopharmacol Biol Psychiatry 2003; 27:85–102
- Laumann EO, Glasser DB, Neves RCS, Moreira ED Jr. A population-based survey of sexual activity, sexual problems and associated help-seeking behavior patterns in mature adults in the United States of America. Int J Impot Res 2009;21:171–8.
- Stahl SM. Basic psychopharmacology of anti-depressants. 1. Clin Psychiatry 1998;59(Suppl 4):5–14
- Damsa C, Bumb A, Bianchi-Demicheli F. Dopamine dependent side-effects of selective serotonin reuptake inhibitors: a clinical review. J Clin Psychiatry 2004;65:1064–8
- Rosen R, Lane R, Menza M. Effects of SSRIs on sexual function: a critical review. J Clin Psychopharmacol 1999;19:67–85
- Montejo-Gonzalez AL, Llorca G, Izquierdo JA, . SSRI-induced sexual dysfunction: fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients. J Sex Marital Ther 1997;23:176–94
- Davison SL, Bell RJ, LaChina M, Holden SL, Davis SR. The relationship between self-reported sexual satisfaction and general well-being in women. J Sex Med 2009;6:2690–7
- Davis S, Katz J, Jackson JL. Sexual desire discrepancies: effects on sexual and relationship satisfaction in heterosexual dating couples. Arch Sex Behav 1999;28:553–67
- Santtila P, Wager I, Witting K, . Discrepancies between sexual desire and sexual activity: gender differences and associations with relationship satisfaction. J Sex Marital Ther 2008;34:29–42
- Witting K, Santtila P, Varjonen M, . Female sexual dysfunction, sexual distress, and compatibility with partner. J Sex Med 2008;5:2587–99
- Brezsnyak M, Whisman MA. Sexual desire and relationship functioning: the effects of marital satisfaction and power. J Sex Marital Ther 2004;30:199–217
- Manderson L. The social and cultural context of sexual function among middle-aged women. Menopause 2005;12:361–2
- Nijs P. Counselling of the climacteric woman: diagnostic difficulties and therapeutic possibilities. Eur J Obstet Gynecol Reprod Biol 1998;81:273–6
- Ferguson JM, Shrivastava RK, Stahl SM, . Reemergence of sexual dysfunction in patients with major depressive disorder: double-blind comparison of nefazodone and sertraline. J Clin Psychiatry 2001;62:24–9
- Kennedy SH, Rizvi S, Fulton K, Rasmussen J. A double-blind comparison of sexual functioning, antidepressant efficacy, and tolerability between agomelatine and venlafaxine XR. J Clin Psychopharmacol 2008;28:329–33
- Clayton AH, Warnock JK, Kornstein SG, Pinkerton R, Sheldon-Keller A, McGarvey EL. A placebo-controlled trial of bupropion SR as an antidote for selective serotonin reuptake inhibitor-induced sexual dysfunction. J Clin Psychiatry 2004; 65:62–7
- Landen M, Eriksson E, Agren H, Fahlen T. Effect of buspirone on sexual dysfunction in depressed patients treated with selective serotonin reuptake inhibitors. J Clin Psychopharmacol 1999;19:268–71
- Michelson D, Kociban K, Tamura R, Morrison MF. Mirtazapine, yohimbine or olanzapine augmentation therapy for serotonin reuptake-associated female sexual dysfunction: a randomized, placebo controlled trial. J Psychiatr Res 2002;36:147–52
- Wheatley D. Triple-blind, placebo-controlled trial of Ginkgo biloba in sexual dysfunction due to antidepressant drugs. Hum Psychopharmacol 2004;19:545–8
- Kang BJ, Lee SJ, Kim MD, Cho MJ. A placebo-controlled, double-blind trial of Ginkgo biloba for antidepressant-induced sexual dysfunction. Hum Psychopharmacol 2002;17:279–84
- Jespersen S, Berk M, Van Wyk C, . A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use. Int Clin Psychopharmacol 2004;19:161–4
- Meston CM. A randomized, placebo-controlled, crossover study of ephedrine for SSRI-induced female sexual dysfunction. J Sex Marital Ther 2004;30:57–68
- Nelson EB, Shah VN, Welge JA, Keck PE Jr. A placebo-controlled, crossover trial of granisetron in SRI-induced sexual dysfunction. J Clin Psychiatry 2001;62:469–73
- Salonia A, Rigatti P, Montorsi F. Sildenafil in erectile dysfunction: a critical review. Curr Med Res Opin 2003;19:241–62
- Berman JR, Berman LA, Toler SM, Gill J, Haughie S. Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder: a double-blind, placebo controlled study. J Urol 2003;170:2333–8
- Nurnberg HG, Hensley PL, Heiman JR, Croft HA, Debattista C, Paine S. Sildenafil treatment of women with antidepressant-associated sexual dysfunction: a randomized controlled trial. JAMA 2008;300:395–404
- Basson R, Brotto LA. Sexual psychophysiology and effects of sildenafil citrate in oestrogenised women with acquired genital arousal disorder and impaired orgasm: a randomised controlled trial. BJOG 2003;110:1014–24
- Davison S, Bell R, Donath S, Montalto J, Davis S. Androgen levels in adult females: changes with age, menopause, and oophorectomy. J Clin Endocrinol Metab 2005;90:3847–53
- Burger HG, Dudley EC, Cui J, Dennerstein L, Hopper JL. A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition. J Clin Endocrinol Metab 2000;85:2832–8
- Davis SR, Davison SL, Donath S, Bell RJ. Circulating androgen levels and self-reported sexual function in women. JAMA 2005;294:91–6
- Rivera-Woll LM, Papalia M, Davis SR, Burger HG. Androgen insufficiency in women: diagnostic and therapeutic implications. Hum Reprod Update 2004;10:421–32
- Uwe DR. The impact of testosterone imbalance on depression and women's health. Maturitas 2002;41(Suppl 1):25–46
- Braunstein GD, Sundwall DA, Katz M, . Safety and efficacy of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial. Arch Intern Med 2005;165:1582–9
- Buster JE, Kingsberg SA, Aguirre O, . Testosterone patch for low sexual desire in surgically menopausal women: a randomized trial. Obstet Gynecol 2005;105:944–52
- Simon J, Braunstein G, Nachtigall L, . Testosterone patch increases sexual activity and desire in surgically menopausal women with hypoactive sexual desire disorder. J Clin Endocrinol Metab 2005;90:5226–33
- Shifren J, Davis SR, Moreau M, . Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the INTIMATE NM1 study. Menopause 2006;13:770–9
- Davis SR, van der Mooren MJ, van Lunsen RHW, . The efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial. Menopause 2006;13:387–96
- Davis SR, Moreau M, Kroll R, . Testosterone for low libido in menopausal women not taking estrogen therapy. N Engl J Med 2008;359:2005–17
- Goldstat R, Briganti E, Tran J, Wolfe R, Davis S. Transdermal testosterone improves mood, well being and sexual function in premenopausal women. Menopause 2003;10:390–8
- Davis SR, Papalia MA, Norman RJ, . Safety and efficacy of a testosterone metered-dose transdermal spray for treatment of decreased sexual satisfaction in premenopausal women: a placebo-controlled randomized, dose-ranging study. Ann Intern Med 2008;148:569–77
- Davis SR, Goldstat R, Papalia MA, . Effects of aromatase inhibition on sexual function and wellbeing in postmenopausal women treated with testosterone: a randomized placebo controlled trial. Menopause 2006;13:37–45
- Shifren JL, Braunstein G, Simon J, . Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. N Engl J Med 2000;343:682–8
- Davis SR. The effects of tibolone on mood and libido. Menopause 2002;9:162–70
- Taylor MJ, Rudkin L, Hawton K. Strategies for managing anti-depressant-induced sexual dysfunction: systematic review of randomised controlled trials. J Affect Disord 2005;88: 241–54
- DeBattista C, Solvason B, Poirier J, Kendrick E, Loraas E. A placebo-controlled, randomized, double-blind study of adjunctive bupropion sustained release in the treatment of SSRI-induced sexual dysfunction. J Clin Psychiatry 2005;66: 844–8
- Masand PS, Ashton AK, Gupta S, Frank B. Sustained-release bupropion for selective serotonin reuptake inhibitor-induced sexual dysfunction: a randomized, double-blind, placebo-controlled, parallel-group study. Am J Psychiatry 2001;158:805–7
- Michelson D, Bancroft J, Targum S, Kim Y, Tepner R. Female sexual dysfunction associated with antidepressant administration: a randomized, placebo-controlled study of pharmacologic intervention. Am J Psychiatry 2000;157:239–43