Impact of multi-morbidity on quality of healthcare and its implications for health policy, research and clinical practice. A scoping review

REFERENCES

• Alwan A. Global status report on noncommunicable diseases 2010. Geneva: World Health Organization; 2011. Available at: http://www.who.int/nmh/publications/ncd_report2010/en/ (accessed 7 December 2014).
   Google Scholar
• Valderas JM, Starfield B, Sibbald B, Salisbury C, Roland M. Defining comorbidity: Implications for understanding health and health services. Ann Fam Med. 2009;7:357–63.
   PubMed Web of Science ®Google Scholar
• Violan C, Foguet-Boreu Q, Flores-Mateo G, Salisbury C, Blom J, Freitag M, et al. Prevalence, determinants and patterns of multimorbidity in primary care: A systematic review of observational studies. PloS one 2014;9:e102149.
   PubMed Web of Science ®Google Scholar
• Starfield B. Threads and yarns: Weaving the tapestry of comorbidity. Ann Fam Med. 2006;4:101–3.
   PubMed Web of Science ®Google Scholar
• Payne RA, Abel GA, Guthrie B, Mercer SW. The effect of physical multimorbidity, mental health conditions and socioeconomic deprivation on unplanned admissions to hospital: A retrospective cohort study. CMAJ 2013;185:E221–28.
   PubMed Web of Science ®Google Scholar
• Cresswell KM, Fernando B, McKinstry B, Sheikh A. Adverse drug events in the elderly. Br Med Bull. 2007;83:259–74.
   PubMed Web of Science ®Google Scholar
• Wehling M. Multimorbidity and polypharmacy: How to reduce the harmful drug load and yet add needed drugs in the elderly? Proposal of a new drug classification: Fit for the aged. J Am Geriatr Soc. 2009;57:560–1.
   Google Scholar
• Nobili A, Garattini S, Mannucci PM. Multiple diseases and polypharmacy in the elderly: Challenges for the internist of the third millennium. J Comorbidity 2011;1:28–44.
   PubMedGoogle Scholar
• Valderas JM, Ricci-Cabello I, Violan-Fors C. The impact of multi-morbidity on quality and safety of healthcare in theory and in practice: A primary care perspective. In: Salisbury C, Fortin M, Mercer S, editors. ABC of multimorbidity. 1st ed. Chichester: John Wiley & Sons; 2014. pp. 38–41.
   Google Scholar
• National Health Service. Quality and outcomes framework United Kingdom: NHS; 2012. Available at: http://www.qof.ic.nhs.uk/ (accessed 7 December 2014).
   Google Scholar
• Colquhoun HL, Levac D, O’Brien KK, Straus S, Tricco AC, Perrier L, et al. Scoping reviews: Time for clarity in definition, methods, and reporting. J Clin Epidemiol. 2014;67:1291–4.
   PubMed Web of Science ®Google Scholar
• Feinstein AR. The pre-therapeutic classification of co-morbidity in chronic disease. J Chron Dis. 1970;23:455–68.
   PubMedGoogle Scholar
• Ritchie C. Health care quality and multimorbidity: The jury is still out. Med Care 2007;45:477–9.
   PubMed Web of Science ®Google Scholar
• Safford MM, Allison JJ, Kiefe CI. Patient complexity: More than comorbidity. the vector model of complexity. J Gen Intern Med. 2007;3:382–90.
   Web of Science ®Google Scholar
• Campbell SM, Roland MO, Buetow SA. Defining quality of care. Soc Sci Med. 2000;51:1611–25.
   PubMed Web of Science ®Google Scholar
• Ahern MM, Hendryx M. Avoidable hospitalizations for diabetes: Comorbidity risks. Dis Manage 2007;10:347–55.
   PubMedGoogle Scholar
• Ani C, Bazargan M, Hindman D, Bell D, Rodriguez M, Baker RS. Comorbid chronic illness and the diagnosis and treatment of depression in safety net primary care settings. J Am Board Fam Med. 2009;22:123–35.
   PubMed Web of Science ®Google Scholar
• Burgers JS, Voerman GE, Grol R, Faber MJ, Schneider EC. Quality and coordination of care for patients with multiple conditions: Results from an international survey of patient experience. Eval Health Prof. 2010;33:343–64.
   PubMed Web of Science ®Google Scholar
• Chaudhry SI, Berlowitz DR, Concato J. Do age and comorbidity affect intensity of pharmacological therapy for poorly controlled diabetes mellitus? J Am Geriatr Soc. 2005;53:1214–6.
   PubMed Web of Science ®Google Scholar
• Desai MM, Rosenheck RA, Druss BG, Perlin JB. Mental disorders and quality of diabetes care in the veterans health administration. Am J Psychiatry 2002;159:1584–90.
   PubMed Web of Science ®Google Scholar
• Druss BG, Zhao L, Cummings JR, Shim RS, Rust GS, Marcus SC. Mental comorbidity and quality of diabetes care under Medicaid: A 50-state analysis. Med Care 2012;50:428–33.
   PubMed Web of Science ®Google Scholar
• Fisher DA, Galanko J, Dudley TK, Shaheen NJ. Impact of comorbidity on colorectal cancer screening in the veterans healthcare system. Clin Gastroenterol Hepatol 2007;5:991–6.
   PubMed Web of Science ®Google Scholar
• Fung CH, Setodji CM, Kung F-Y, Keesey J, Asch SM, Adams J, et al. The relationship between multimorbidity and patients’ ratings of communication. J Gen Intern Med. 2008;23:788–93.
   PubMed Web of Science ®Google Scholar
• Gulliford M, Cowie L, Morgan M. Relational and management continuity survey in patients with multiple long-term conditions. J Health Serv Res Policy 2011;16:67–74.
   PubMed Web of Science ®Google Scholar
• Halanych JH, Safford MM, Keys WC, Person SD, Shikany JM, Kim YI, et al. Burden of comorbid medical conditions and quality of diabetes care. Diabetes Care 2007;30:2999–3004.
   PubMed Web of Science ®Google Scholar
• Harman JS, Edlund MJ, Fortney JC, Kallas H. The influence of comorbid chronic medical conditions on the adequacy of depression care for older Americans. J Am Geriatr Soc. 2005;53:2178–83.
   PubMed Web of Science ®Google Scholar
• Higashi T, Wenger NS, Adams JL, Fung C, Roland M, McGlynn EA, et al. Relationship between number of medical conditions and quality of care. N Engl J Med. 2007;356:2496–504.
   PubMed Web of Science ®Google Scholar
• Lagu T, Weiner MG, Hollenbeak CS, Eachus S, Roberts CS, Schwartz JS, et al. The impact of concordant and discordant conditions on the quality of care for hyperlipidemia. J Gen Intern Med. 2008;23:1208–13.
   PubMed Web of Science ®Google Scholar
• Min LC, Wenger NS, Fung C, Chang JT, Ganz DA, Higashi T, et al. Multimorbidity is associated with better quality of care among vulnerable elders. Med care 2007;45:480–8.
   PubMed Web of Science ®Google Scholar
• Parchman ML, Noel PH, Lee S. Primary care attributes, health care system hassles, and chronic illness. Med Care 2005;43: 1123–9.
   PubMed Web of Science ®Google Scholar
• Pentakota SR, Rajan M, Fincke BG, Tseng C-L, Miller DR, Christiansen CL, et al. Does diabetes care differ by type of chronic comorbidity?: An evaluation of the Piette and Kerr framework. Diabetes care 2012;35:1285–92.
   PubMed Web of Science ®Google Scholar
• Petersen LA, Woodard LD, Henderson LM, Urech TH, Pietz K. Will hypertension performance measures used for pay-for- performance programs penalize those who care for medically complex patients? Circulation 2009;119:2978–85.
   PubMed Web of Science ®Google Scholar
• Schnitzer S, Kuhlmey A, Adolph H, Holzhausen J, Schenk L. Complaints as indicators of health care shortcomings: Which groups of patients are affected? Int J Qual Health Care 2012; 24:476–82.
   PubMed Web of Science ®Google Scholar
• Singh JA, Hodges JS, Asch SM. Opportunities for improving medication use and monitoring in gout. Ann Rheum Dis. 2009; 68:1265–70.
   PubMed Web of Science ®Google Scholar
• Teh CF, Reynolds CF 3rd, Cleary PD. Quality of depression care for people with coincident chronic medical conditions. Gen Hosp Psychiatry 2008;30:528–35.
   PubMed Web of Science ®Google Scholar
• Turner BJ, Hollenbeak CS, Weiner M, Ten Have T, Tang SS. Effect of unrelated comorbid conditions on hypertension management. Ann Intern Med. 2008;148:578–86.
   PubMed Web of Science ®Google Scholar
• Virani SS, Woodard LD, Chitwood SS, Landrum CR, Urech TH, Wang D, et al. Frequency and correlates of treatment intensification for elevated cholesterol levels in patients with cardiovascular disease. Am Heart J. 2011;162:725–32e1.
   PubMed Web of Science ®Google Scholar
• Vitry AI, Roughead EE, Preiss AK, Ryan P, Ramsay EN, Gilbert AL, et al. Influence of comorbidities on therapeutic progression of diabetes treatment in Australian veterans: A cohort study. PloS One 2010;5:e14024.
   PubMed Web of Science ®Google Scholar
• Voorham J, Haaijer-Ruskamp FM, Wolffenbuttel BH, de Zeeuw D, Stolk RP, Denig P. Differential effects of comorbidity on antihypertensive and glucose-regulating treatment in diabetes mellitus—a cohort study. PloS One 2012;7:e38707.
   PubMed Web of Science ®Google Scholar
• Werner RM, Chang VW. The relationship between measured performance and satisfaction with care among clinically complex patients. J Gen Intern Med. 2008;23:1729–35.
   PubMed Web of Science ®Google Scholar
• Woodard LD, Landrum CR, Urech TH, Wang D, Virani SS, Petersen LA. Impact of clinical complexity on the quality of diabetes care. Am J Manag Care 2012;18:508–14.
   PubMed Web of Science ®Google Scholar
• Woodard LD, Urech T, Landrum CR, Wang D, Petersen LA. Impact of comorbidity type on measures of quality for diabetes care. Med Care 2011;49:605–10.
   PubMed Web of Science ®Google Scholar
• Mand P, Roth K, Biertz F, Kersting M, Kruschinski C, Schmiemann G, et al. Drug-disease interaction in elderly patients in family practice. Int J Clin Pharmacol Ther. 2014;52:337–45.
   PubMed Web of Science ®Google Scholar
• Min L, Kerr EA, Blaum CS, Reuben D, Cigolle C, Wenger N. Contrasting effects of geriatric versus general medical multimorbidity on quality of ambulatory care. J Am Geriatr Soc. 2014; 62:1714–21.
   PubMed Web of Science ®Google Scholar
• Tsang C, Bottle A, Majeed A, Aylin P. Adverse events recorded in English primary care: observational study using the general practice research database. Br J Gen Pract. 2013;63:e534–42.
   PubMed Web of Science ®Google Scholar
• Buja A, Gini R, Visca M, Damiani G, Federico B, Donato D, et al. Need and disparities in primary care management of patients with diabetes. BMC Endocr Disord. 2014;14:56.
   PubMedGoogle Scholar
• Doubova SV, Lamadrid-Figueroa H, Perez-Cuevas R. Use of electronic health records to evaluate the quality of care for hypertensive patients in Mexican family medicine clinics. J Hypertens. 2013;31:1714–23.
   PubMed Web of Science ®Google Scholar
• Wirtz HS, Boudreau DM, Gralow JR, Barlow WE, Gray S, Bowles EJ, et al. Factors associated with long-term adherence to annual surveillance mammography among breast cancer survivors. Breast Cancer Res Treat. 2014;143:541–50.
   PubMed Web of Science ®Google Scholar
• Cancian M, Battaggia A, Celebrano M, Del Zotti F, Novelletto BF, Michieli R, et al. The care for chronic heart failure by general practitioners. Results from a clinical audit in Italy. Eur J Gen Pract. 2013;19:3–10.
   PubMed Web of Science ®Google Scholar
• Frigola-Capell E, Verdu-Rotellar JM, Comin-Colet J, Davins-Miralles J, Hermosilla E, Wensing M, et al. Prescription in patients with chronic heart failure and multimorbidity attended in primary care. Qual Prim Care 2013;21:211–9.
   PubMedGoogle Scholar
• Werner-Busse A, Kostev K, Heine G, Worm M. Impact of comorbidities on the treatment of atopic dermatitis in clinical practice. Int J Clin Pharmacol Ther. 2014;52:726–31.
   PubMed Web of Science ®Google Scholar
• Sharif R, Cuevas CR, Wang Y, Arora M, Sharma G. Guideline adherence in management of stable chronic obstructive pulmonary disease. Respir Med. 2013;107:1046–52.
   PubMed Web of Science ®Google Scholar
• Piette JD, Kerr EA. The impact of comorbid chronic conditions on diabetes care. Diabetes Care 2006 29:725–31.
   PubMed Web of Science ®Google Scholar
• Huntley AL, Johnson R, Purdy S, Valderas JM, Salisbury C. Measures of multimorbidity and morbidity burden for use in primary care and community settings: A systematic review and guide. Ann Fam Med. 2012;10:134–41.
   PubMed Web of Science ®Google Scholar
• Islam MM, Valderas JM, Yen L, Dawda P, Jowsey T, McRae IS. Multimorbidity and comorbidity of chronic diseases among the senior Australians: Prevalence and patterns. PloS one 2014; 9:e83783.
   PubMed Web of Science ®Google Scholar
• Lugtenberg M, Burgers JS, Clancy C, Westert GP, Schneider EC. Current guidelines have limited applicability to patients with comorbid conditions: A systematic analysis of evidence-based guidelines. PloS One 2011;6:e25987.
   PubMed Web of Science ®Google Scholar
• Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu AW. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: Implications for pay for performance. J Am Med Assoc. 2005;294:716–24.
   PubMed Web of Science ®Google Scholar
• Boyd CM, Leff B, Wolff JL, Yu Q, Zhou J, Rand C, et al. Informing clinical practice guideline development and implementation: Prevalence of coexisting conditions among adults with coronary heart disease. J Am Geriatr Soc. 2011;59:797–805.
   PubMed Web of Science ®Google Scholar
• Fortin M, Stewart M, Poitras ME, Almirall J, Maddocks H. A systematic review of prevalence studies on multimorbidity: Toward a more uniform methodology. Ann Fam Med. 2012;10: 142–51.
   PubMed Web of Science ®Google Scholar
• Smith SM, Soubhi H, Fortin M, Hudon C, O’Dowd T. Interventions for improving outcomes in patients with multimorbidity in primary care and community settings. Cochrane Database Syst Rev. 2012;4:CD006560.
   Google Scholar
• Roland M, Paddison C. Better management of patients with multimorbidity. Br Med J. 2013;346:f2510.
   PubMed Web of Science ®Google Scholar
• Starfield B, Shi L, Macinko J. Contribution of primary care to health systems and health. Milbank Q. 2005;83:457–502.
   PubMed Web of Science ®Google Scholar
• BMA. QOF guidance 2012–2013 (fifth revision). Available at: http://bma.org.uk/practical-support-at-work/contracts/independent-contractors/qof-guidance (accessed 7 December 2014).
   Google Scholar
• Muth C, Beyer M, Fortin M, Rochon J, Oswald F, Valderas JM, et al. Multimorbidity's research challenges and priorities from a clinical perspective: The case of ‘Mr Curran’. Eur J Gen Pract. 2014;20:139–47.
   PubMed Web of Science ®Google Scholar
• May C, Montori VM, Mair FS. We need minimally disruptive medicine. Br Med J. 2009;339:b2803.
   PubMed Web of Science ®Google Scholar
• Lin GA, Dudley RA. Patient-centered care: What is the best measuring stick? Arch Intern Med. 2009;169:1551–3.
   PubMed Web of Science ®Google Scholar