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Research Reports

Association Analysis of Polymorphisms in Genes Related to Oxidative Stress in South Indian Type 2 Diabetic Patients with Retinopathy

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Pages 1-8 | Received 09 Aug 2013, Accepted 09 Feb 2014, Published online: 12 Mar 2014

References

  • Rema M, Premkumar S, Anitha B, et al. Prevalence of diabetic retinopathy in urban India: The Chennai Urban Rural Epidemiology Study (CURES) Eye Study, I. Invest Ophthalmol Vis Sci 2005;46:2328–2333
  • Klein R, Klein BEK, Moss SE, Cruickshanks KJ. Relationship of hyperglycemia to the long-term incidence and progression of diabetic retinopathy. Arch Intern Med 1994;154:2169–2178
  • DCCT. The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control and complications trial. Diabetes 1995;44:968–983
  • Stratton IM, Adler AI, Neil HAW, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000;321:405–412
  • Liu Y, Wang M, Morris AD, et al. Glycemic exposure and blood pressure influencing progression and remission of diabetic retinopathy: a longitudinal cohort study in GoDARTS. Diabetes Care 2013;36:3979–3984
  • Ceriello A. Oxidative stress and diabetes-associated complications. Endocr Pract 2006;12:60–62
  • Nishikawa T, Edelstein D, Brownlee M. The missing link: a single unifying mechanism for diabetic complications. Kidney Int 2000;77:S26–S30
  • Du Y, Miller CM, Kern TS. Hyperglycemia increases mitochondrial superoxide in retina and retinal cells. Free Radic Biol Med 2003;35:1491–1499
  • Leslie RD, Pyke DA. Diabetic retinopathy in identical twins. Diabetes 1982;31:19–21
  • Hietala K, Forsblom C, Summanen P, Groop PH. Heritability of proliferative diabetic retinopathy. Diabetes 2008;57:2176–2180
  • Danser AH, Derkx FH, Admiraal PJ, et al. Angiotensin levels in the eye. Invest Ophthalmol Vis Sci 1994;35:1008–1018
  • Nagi DK, Mansfield MW, Stickland MH, Grant PJ. Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, and diabetic retinopathy in subjects with IDDM and NIDDM. Diabet Med 1995;12:997–1001
  • Doi Y, Yoshizumi H, Yoshinari M, et al. Association between a polymorphism in the angiotensin converting enzyme gene and microvascular complications in Japanese patients with NIDDM. Diabetologia 1996;39:97–102
  • Araz M, Yilmaz N, Gungor K, et al. Angiotensin-converting enzyme gene polymorphism and microvascular complications in Turkish type 2 diabetic patients. Diabetes Res Clin Pract 2001;54:95–104
  • Toda N, Nakanishi-Toda M. Nitric oxide: ocular blood flow, glaucoma, and diabetic retinopathy. Prog Retin Eye Res 2007;26:205–238
  • Awata T, Neda T, Iizuka H, et al. Endothelial nitric oxide synthase gene is associated with diabetic macular edema in type 2 diabetes. Diabetes Care 2004;27:2184–2190
  • Ezzidi I, Mtiraoui N, Mohamed MB, et al. Endothelial nitric oxide synthase, Glu298Asp, 4b/a, and T-786C polymorphisms in type 2 diabetic retinopathy. Clin Endocrinol 2008;68:542–546
  • de Syllos RW, Sandrim VC, Lisboa HR, et al. Endothelial nitric oxide synthase genotype and haplotype are not associated with diabetic retinopathy in type 2 diabetes patients. Nitric Oxide 2006;15:417–422
  • Suganthalakshmi B, Anand R, Kim R, et al. Association of VEGF and eNOS gene polymorphisms in type 2 diabetic retinopathy. Mol Vis 2006;12:336–341
  • Uthra S, Raman R, Mukesh BN, et al. Intron 4 VNTR of endothelial nitric oxide synthase (eNOS) gene and diabetic retinopathy in type 2 patients in southern India. Ophthalmic Genet 2007;28:77–81
  • Al-Shabrawey M, Bartoli M, El-Remessy A, et al. Role of NADPH Oxidase and Stat3 in statin-mediated protection against diabetic retinopathy. Invest Ophthalmol Vis Sci 2008;49:3231–3238
  • Matsunaga-Irie S, Maruyama T, Yamamoto Y, et al. Relation between development of nephropathy and the p22phox C242T and receptor for advanced glycation end product G1704T gene polymorphisms in type 2 diabetic patients. Diabetes Care 2004;27:303–307
  • Zheng L, Szabó C, Kern TS. Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB. Diabetes 2004;53:2960–2967
  • Mabley JG, Feng Y, Hagen F, et al. Poly(ADP-ribose) polymerase and diabetic retinopathy. FASEB J 2004;18:A1189
  • Lunn RM, Langlois RG, Hsieh LL, et al. XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res 1999;59:2557–2561
  • Lahiri DK, Nurnberger JI. A rapid nonenzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nuc Acids Res 1991;19:5444
  • Obrosova IG, Minchenko AG, Frank RN, et al. Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression. Int J Mol Med 2004;14:55–64
  • Wang XG, Wang ZQ, Tong WM, Shen Y. PARP1 Val762Ala polymorphism reduces enzymatic activity. Biochem Biophys Res Commun 2007;354:122–126
  • Caldecott KW, Aoufouchi S, Johnson P, Shall S. XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly ADP-ribose polymerase, and DNA ligase III is a novel molecular ‘nick-sensor’ in vitro. Nucleic Acids Res 1996;24:4387–4394
  • Shen MR, Jones IM, Mohrenweiser H. Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res 1998;58:604–608
  • Fujisawa T, Ikegami H, Kawaguchi Y, et al. Meta-analysis of association of insertion/deletion polymorphism of angiotensin 1 converting enzyme with diabetic nephropathy and retinopathy. Diabetologia 1998;41:47–53
  • Lu Y, Ge Y, Hu Q, et al. Association between angiotensin-converting enzyme gene polymorphism and diabetic retinopathy in the Chinese population. J Renin Angiotensin Aldosterone Syst 2012;13:289–295
  • Neugebauer S, Baba T, Watanabe T. Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes. Diabetes 2000;49:500–503
  • Shimizu T, Onuma T, Kawamori R, et al. Endothelial nitric oxide synthase gene and the development of diabetic nephropathy. Diabetes Res Clin Pract 2002;58:179–185
  • Abhary S, Hewitt AW, Burdon KP, Craig JE. A systematic meta-analysis of genetic association studies for diabetic retinopathy. Diabetes 2009;58:2137–2147
  • Klein R, Klein BE, Moss SE, et al. The Wisconsin epidemiologic study of diabetic retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol 1984;102:520–526
  • Kohner EM. Diabetic retinopathy. Br Med Bull 1989;45:148–173
  • Ferris FL 3rd, Chew KY, Hoogwerf BJ. Serum lipids and diabetic retinopathy. Early Treatment Diabetic Retinopathy Study Research Group. Diabetes Care 1996;19:1291–1293
  • Fernandez-Robredo P, Moya D, Rodriguez JA, Garcia-Layana A. Vitamins C and E reduce retinal oxidative stress and nitric oxide metabolites and prevent ultrastructural alterations in porcine hypercholesterolemia. Invest Ophthalmol Vis Sci 2005;46:1140–1146

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