939
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Cerebroprotective effect of Ocimum gratissimum against focal ischemia and reperfusion-induced cerebral injury

, &
Pages 175-181 | Received 08 Apr 2010, Accepted 02 Jul 2010, Published online: 25 Oct 2010

References

  • Aguiyi JC, Obi CI, Gang SS, Igweh AC. (2000). Hypoglycaemic activity of Ocimum gratissimum in rats. Fitoterapia, 71, 444–446.
  • Beauchamp C, Fridovich I. (1971). Superoxide dismutase, improved assays and an assay applicable to acrylamide gels. Anal Biochem, 44, 276–287.
  • Bochelen D, Rudin M, Sauter A. (1999). Calcineurin inhibitor FK 506 and SDZASM 981 alleviate the outcome of focal ischemia/reperfusion injury. J Pharmacol Exp Ther, 288, 653–659.
  • Bromont C, Marie C, Bralet J. (1989). Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats. Stroke, 20, 918–924.
  • Chan PH. (2001). Reactive oxygen radicals in signalling and damage in the ischemic brain. J Cereb Blood Metab, 21, 2–14.
  • Crack PJ, Taylor JM, Flentjar NJ, de Haan J, Hertzog P, Iannello RC. (2001). Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury. J Neurochem, 78, 1389–1399.
  • Cristiana M, Murbach FM, Ortiz M, Marques MC. (2006). Effects of seasonal variation on the central nervous system activity of Ocimum gratissimum L. essential oil. J Ethnopharmacol, 105, 161–166.
  • Dib M, Garrel C, Favier A, Robin V, Desnuelle C. (2002). Can malondialdehyde be used as a biological marker of progression in neurodegenerative disease? J Neurol, 249, 367–374.
  • Dunham NW, Miya TS. (1957). A note on simple apparatus for detecting neurological deficits in rats and mice. J Am Pharm Assoc Am Pharm Assoc, 46, 208–211.
  • Easton JD, Hansen SL, Martin JB. (1998). Cerebrovascular diseases. In: Fanci AS, Bravnwald E, Isselbacher KJ,Wilson JD, Martin JB, Kasper DL, eds. Principles of Internal Medicine. New York: McGraw-Hill, 2325.
  • E-Jian L, Hung-Yi C, Yu-Chang H, Tsung-Ying C, Ming-Yang L, Shu-Ching Y. (2009). Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia. Exp Neurol, 217, 74–83.
  • Evans PH. (1993). Free radicals in brain metabolism and pathology. Br Med Bull, 49, 577–587.
  • Evans WC. (2002). Carbohydrates. In: Evans WC, Evans D, eds. Trease and Evan’s Pharmacognosy, fifteenth edition. Edinburgh, London: WB Saunders, 93–213.
  • Farnsworth NR. (1966). Biological and phytochemical screening of plants. J Pharm Sci, 55, 225–276.
  • Feeney DM, Beyeson MG, Linn RT, Murray HM, Dail WG. (1981). Responses to cortical injury: Methodology and local effects of contusions in the rat. Brain Research, 211, 67–77.
  • Gupta R, Singh M, Sharma A. (2003). Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury. Pharmacol Res, 48, 209–215.
  • Imaizumi S, Kayama T, Suzuki J. (1984). Chemiluminescence in hypoxic brain-the first report. Correlation between energy metabolism and free radical reaction. Stroke, 15, 1061–1065.
  • Itoh J, Nabeshima T, Kammeyama T. (1990). Utility of an elevated plus maze for the evaluation of memory in mice. Effect of nootropic scopolamine and electroconvulsive shock. Psychopharmacology, 101, 27–32.
  • Janardhan V, Qureshi AI. (2004). Mechanisms of ischemic brain injury. Curr Cardiol Rep, 6, 117–123.
  • Janssen AM, Scheffer JJC, Ntezurubanza L, Baerheim SA. (1989). Antimicrobial activities of some Ocimum species grown in Rwanda. J Ethnopharmacol, 26, 57–63.
  • Jenkin LW, Povlishock JT, Lewett W, Miller JD, Becker DP. (1981). The role of post-ischemic recirculation in the development of ischemic neuronal injury following complete cerebral ischemia. Acta Neuropathologica, 5, 205–220.
  • Kulkarni SK. (2007). Hand Book of Experimental Pharmacology, third edition. Delhi: Vallabh Prakashan, 36–38.
  • Lin CC, Lin JK, Chang CH. (1995). Evaluation of hepatoprotective effects of “Chhit-Chan-Than” from Taiwan. Int J Pharmacog, 33, 139–143.
  • List PH, Horhammer L. (1977). Hagers Handbuch der Pharmazeutischen Praxis, fourth edition. Band VI A, Berlin-Heidelberg, Germany: Springer.
  • Longa EZ, Weinstein PR, Carlson S, Cummins R. (1989). Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke, 20, 84–91.
  • Lowry OH, Rosebrough NJ, Far AL, Randall RJ. (1951). Protein measurement with folin-phenol reagent. J Biol Chem, 93, 265–275.
  • Lukmanul HF, Girija A, Boopathy R. (2008). Antioxidant property of selected Ocimum species and their secondary metabolite content. J Med Plants Res, 2, 250–257.
  • Mohandas J, Marshall JJ, Duggin GG, Horvath JS, Tiller D. (1984). Differential distribution of glutathione and glutathione related enzymes in rabbit kidney, possible implications in analgesic neuropathy. Cancer Res, 44, 5086–5091.
  • Ndounga M, Ouamba JM. (1997). Antibacterial and antifungal activities of essential oils of Ocimum gratissimum and O. basilicum from Congo. Fitoterapia, 68, 190–191.
  • Offiah VN, Chikwendu UA. (1999). Antidiarrhoeal effects of Ocimum gratissimum leaf extract in experimental animals. J Ethnopharmacol, 68, 327–330.
  • Oliver CN, Starke-Reed PE, Stadtman ER, Liu GJ, Carney JM, Floyd RA. (1990). Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc Natl Acad Sci USA, 87, 5144–5147.
  • Pitchersky E, Gang DR. (2000). Genetics and biochemistry of secondary metabolites in plants: An evolutionary perspective. Trends Plant Sci, 5, 459–445.
  • Roberto FV, Renee JG, Alan P, James ES. (2001). Genetic diversity of Ocimum gratissimum L. based on volatile oil constituents, flavonoids and RAPD markers. Biochem Syst Ecol, 29, 287–304.
  • Singleton VL, Orthofer R, Lamuela-Ravento’s RM. (1999). Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. In: Packer L, ed. Methods in Enzymology. San Diego CA: Academic Press, 152–178.
  • Taku SM, Fujimura NN, Gyung WK, Atsushi ST, Hayashi P, Narasimhan C. (2004). Neuronal death/survival signaling pathways in cerebral ischemia. J Am Soc Exp Neuro Ther, 1, 17–25.
  • Veronica NO, Unoma AC. (1999). Antidiarrhoeal effects of Ocimum gratissimum leaf extract in experimental animals. J Ethnopharmacol, 68, 327–330.
  • Yagi K. (1982). Assay for serum lipid peroxide level and its clinical significance. In: Yagi K, ed. Lipid Peroxides in Biology and Medicine. New York: Academic Press, 232.
  • Yousuf S, Atif F, Ahmad M, Hoda N, Ishrat T, Khan B. (2009). Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia. Brain Res, 1250, 242–253.
  • Zdenek H, Ivan K. (1998). Concurrent administration of sub effective doses of scopolamine and MK-801 produces a short-term amnesia for elevated plus-maze in mice. Behav Brain Res, 91, 83–89.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.