209
Views
2
CrossRef citations to date
0
Altmetric
Research Article

The human heart releases cardiotrophin-1after coronary artery bypass grafting with cardiopulmonary bypass

, , , , &
Pages 252-256 | Received 01 Nov 2011, Accepted 02 May 2011, Published online: 15 Jun 2011

References

  • Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh SM, . Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA. 1995;92:1142–6.
  • Wollert KC, Taga T, Saito M, Narazaki M, Kishimoto T, Glembotski CC, . Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/ leukemia inhibitory factor receptor-dependent pathways. J Biol Chem. 1996;271: 9535–45.
  • Pennica D, Wood WI, Chien KR. Cardiotrophin-1: A multifunctional cytokine that signals via LIF receptor-gp 130 dependent pathways. Cytokine Growth Factor Rev. 1996;7:81–91.
  • Kuwahara K, Saito Y, Kishimoto I, Miyamoto Y, Harada M, Ogawa E, . Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes. J Mol Cell Cardiol. 2000;32:1385–94.
  • Sheng Z, Knowlton K, Chen J, Hoshijima M, Brown JH, Chien KR. Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy. J Biol Chem. 1997;272:5783–91.
  • Brar BK, Stephanou A, Pennica D, Latchman DS. CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1/2 pathways. Cytokine. 2001;16:93–6.
  • Pennica D, Swanson TA, Shaw KJ, Kuang WJ, Gray CL, Beatty BG, . Human cardiotrophin-1: Protein and gene structure, biological and binding activities, and chromosomal localization. Cytokine. 1996;8:183–9.
  • Hishinuma S, Funamoto M, Fujio Y, Kunisada K, Yamauchi-Takihara K. Hypoxic stress induces cardiotrophin-1 expression in cardiac myocytes. Biochem Biophys Res Commun. 1999;264:436–40.
  • Talwar S, Squire IB, Downie PF, Davies JE, Ng LL. Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina. Heart. 2000;84:421–4.
  • Talwar S, Squire IB, Downie PF, O'Brien RJ, Davies JE, Ng LL. Elevated circulating cardiotrophin-1 in heart failure: Relationship with parameters of left ventricular systolic dysfunction. Clin Sci (Lond). 2000;99:83–8.
  • Talwar S, Squire IB, O'Brien RJ, Downie PF, Davies JE, Ng LL. Plasma cardiotrophin-1 following acute myocardial infarction: Relationship with left ventricular systolic dysfunction. Clin Sci (Lond). 2002;102:9–14.
  • Wei M, Ren S, Liu J, Li P, Qian H, Tarkka M. Perioperative plasma brain natriuretic peptide and cardiotrophin-1 in off-pump coronary artery bypass. Scand Cardiovasc J. 2008;42:399–404.
  • Asai S, Saito Y, Kuwahara K, Mizuno Y, Yoshimura M, Higashikubo C, . The heart is a source of circulating cardiotrophin-1 in humans. Biochem Biophys Res Comm. 2000;279:320–3.
  • Stejskal D, Ruzicka V. Cardiotrophin-1 review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2008;152:9–19.
  • Liao Z, Brar BK, Cai Q, Stephanou A, O'Leary RM, Pennica D, . Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion. Cardiovasc Res. 2002;53:902–10.
  • Ruixing Y, Dezhai Y, Jiaquan L. Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction. J Med Invest. 2004;51: 29–37.
  • Ruixing Y, Jinzhen W, Dezhai Y, Jiaquan L. Cardioprotective role of cardiotrophin-1 gene transfer in a murine model of myocardial infarction. Growth Factors. 2007;25:286–94.
  • Song J, Zhang YW, Yao AH, Yu Y, Hua ZY, Pu LY, . Adenoviral cardiotrophin-1 transfer improves survival and early graft function after ischemia and reperfusion in rat small-for-size liver transplantation model. Transpl Int. 2008;21:372–83.
  • Marqučs JM, Belza I, Holtmann B, Pennica D, Prieto J, Bustos M. Cardiotrophin-1 is an essential factor in the natural defense of the liver against apoptosis. Hepatology. 2007;45:639–48.
  • Ghosh S, Ng LL, Talwar S, Squire IB, Galiñanes M . Cardiotrophin-1 protects the human myocardium from ischemic injury. Comparison with the first and second window of protection by ischemic preconditioning. Cardiovasc Res. 2000;48:440–7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.