Endothelial nitric oxide synthase gene variants and haplotypes associated with an increased risk of idiopathic recurrent miscarriage

References

• Baek, K.H., Lee, E.J., & Kim, Y.S. (2007). Recurrent pregnancy loss: the key potential mechanisms. Trends in Molecular Medicine, 13, 310–317.
   PubMed Web of Science ®Google Scholar
• Bashford, M.T., Hefler, L.A., Vertrees, T.W., Roa, B.B., & Gregg, A.R. (2001). Angiotensinogen and endothelial nitric oxide synthase gene polymorphisms among Hispanic patients with preeclampsia. American Journal of Obstetrics and Gynecology, 184, 1345–1351.
   PubMed Web of Science ®Google Scholar
• Buchholz, T., Lohse, P., Kosian, E., & Thaler, C.J. (2004). Vasoconstrictively acting AT1R A1166C and NOS3 4/5 polymorphisms in recurrent spontaneous abortions (RSA). American Journal of Reproductive Immunology, 51, 323–328.
   PubMed Web of Science ®Google Scholar
• Chatterjee, A., Black, S.M., & Catravas, J.D. (2008). Endothelial nitric oxide (NO) and its pathophysiologic regulation. Vascular Pharmacology, 49, 134–140.
   PubMed Web of Science ®Google Scholar
• Ezzidi, I., Mtiraoui, N., Mohamed, M.B., Mahjoub, T., Kacem, M., & Almawi, W.Y. (2008). Association of endothelial nitric oxide synthase Glu298Asp, 4b/a, and −786T> C gene variants with diabetic nephropathy. Journal of Diabetes and its Complications, 22, 331–338.
   PubMed Web of Science ®Google Scholar
• Fan, W., Li, S.W., & Wang, Y. (2007). Association of genetic polymorphisms in endothelial nitric oxide synthase 3 gene with recurrent early spontaneous abortion. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 24, 23–26.
   Google Scholar
• Hefler, L.A., Tempfer, C.B., Bashford, M.T., Unfried, G., Zeillinger, R., Schneeberger, C., et al. (2002). Polymorphisms of the angiotensinogen gene, the endothelial nitric oxide synthase gene, and the interleukin-1b gene promoter in women with idiopathic recurrent miscarriage. Molecular Human Reproduction, 8, 95–100.
   PubMed Web of Science ®Google Scholar
• Hillermann, R., Carelse, K., & Gebhardt, G.S. (2005). The Glu298Asp variant of the endothelial nitric oxide synthase gene is associated with an increased risk for abruptio placentae in pre-eclampsia. Journal of Human Genetics, 50, 415–419.
   PubMed Web of Science ®Google Scholar
• Karaer, A., Karaer, K., Ozaksit, G., Ceylaner, S., & Percin, E.F. (2008). Y chromosome azoospermia factor region microdeletions and recurrent pregnancy loss. American Journal of Obstetrics and Gynecology, 199, 662.e1–e5.
   PubMed Web of Science ®Google Scholar
• Karvela, M., Papadopoulou, S., Tsaliki, E., Konstantakou, E., Hatzaki, A., Florentin-Arar, L., & Lamnissou, K. (2008). Endothelial nitric oxide synthase gene polymorphisms in recurrent spontaneous abortions. Archives of Gynecology and Obstetrics, 278, 349–352.
   PubMed Web of Science ®Google Scholar
• Kumar, S. (2011). Occupational, environmental and lifestyle factors associated with spontaneous abortion. Reproductive Sciences, 18, 915–930.
   PubMed Web of Science ®Google Scholar
• Leeson, C.P., Hingorani, A.D., Mullen, M.J., Jeerooburkhan, N., Kattenhorn, M., Cole, T.J., et al. (2002). Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. Circulation Research, 90, 1153–1158.
   PubMed Web of Science ®Google Scholar
• Li, R., Lyn, D., Lapu-Bula, R., Oduwole, A., Igho-Pemu, P., Lankford, B., et al. (2004). Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans. American Journal of Hypertension, 17, 560–567.
   PubMed Web of Science ®Google Scholar
• Li, T.C., Makris, M., Tomsu, M., Tuckerman, E., & Laird, S. (2002). Recurrent miscarriage: aetiology, management and prognosis. Human Reproduction Update, 8, 463–481.
   PubMed Web of Science ®Google Scholar
• Makino, A., Nakanishi, T., Sugiura-Ogasawara, M., Ozaki, Y., Suzumori, N., & Suzumori, K. (2004). No association of C677T methylenetetrahydrofolate reductase and an endothelial nitric oxide synthase polymorphism with recurrent pregnancy loss. American Journal of Reproductive Immunology, 52, 60–66.
   PubMed Web of Science ®Google Scholar
• Marroni, A.S., Metzger, I.F., Souza-Costa, D.C., Nagassaki, S., Sandrim, V.C., Correa, R.X., et al. (2005). Consistent interethnic differences in the distribution of clinically relevant endothelial nitric oxide synthase genetic polymorphisms. Nitric Oxide, 12, 177–182.
   PubMed Web of Science ®Google Scholar
• Nakayama, M., Yoshimura, M., Sakamoto, T., Abe, K., Yamamuro, M., Shono, M., et al. (2006). A −786T> C polymorphism in the endothelial nitric oxide synthase gene reduces serum nitrite/nitrate levels from the heart due to an intracoronary injection of acetylcholine. Pharmacogenetics and Genomics, 16, 339–345.
   PubMed Web of Science ®Google Scholar
• Ozturk, E., Balat, O., Pehlivan, S., Ugur, M.G., Ozcan, C., Sever, T., & Kul, S. (2011). Endothelial nitric oxide synthase gene polymorphisms in preeclampsia with or without eclampsia in a Turkish population. Journal of Obstetrics and Gynaecology Research, 37, 1778–1783.
   PubMed Web of Science ®Google Scholar
• Parveen, F., Faridi, R.M., Alam, S., & Agrawal, S. (2011). Genetic analysis of eNOS gene polymorphisms in association with recurrent miscarriage among North Indian women. Reproductive Biomedicine Online, 23, 124–131.
   PubMed Web of Science ®Google Scholar
• Persu, A., Stoenoiu, M.S., Messiaen, T., Davila, S., Robino, C., El-Khattabi, O., et al. (2002). Modifier effect of eNOS in autosomal dominant polycystic kidney disease. Human Molecular Genetics, 11, 229–241.
   PubMed Web of Science ®Google Scholar
• Saidi, S., Mallat, S.G., Almawi, W.Y., & Mahjoub, T. (2010). Endothe lial nitric oxide synthase Glu298Asp, 4b/a, and −786T> C gene polymorphisms and the risk of ischemic stroke. Acta Neurologica Scandinavica, 121, 114–119.
   PubMed Web of Science ®Google Scholar
• Salimi, S., Firoozrai, M., Nourmohammadi, I., Shabani, M., Shafiee, S.M., Mohebbi, A., & Tavilani, H. (2008). Lack of evidence for contribution of intron4a/b polymorphism of endothelial nitric oxide synthase (NOS3) gene to plasma nitric oxide levels. Acta Cardiologica, 63, 229–234.
   Web of Science ®Google Scholar
• Sandrim, V.C., Palei, A.C., Cavalli, R.C., Araujo, F.M., Ramos, E.S., Duarte, G., & Tanus-Santos, J.E. (2008). ENOS haplotypes associated with gestational hypertension or preeclampsia. Pharmacogenomics, 9, 1467–1473.
   PubMed Web of Science ®Google Scholar
• Shimasaki, Y., Yasue, H., Yoshimura, M., Nakayama, M., Kugiyama, K., Ogawa, H., et al. (1998). Association of the missence Glu298Asp variant of the endothelial nitric oxide gene with myocardial infarction. Journal of the American College of Cardiology, 31, 1506–1510.
   PubMed Web of Science ®Google Scholar
• Shin, S.J, Lee, H.H., Cha, S.H., Kim, J.H., Shim, S.H., Choi, D.H., & Kim, N.K. (2010). Endothelial nitric oxide synthase gene polymorphisms (−786T> C, 4a4b, 894G> T) and haplotypes in Korean patients with recurrent spontaneous abortion. European Journal of Obstetrics, Gynecology and Reproductive Bioogy, 152, 64–67.
   PubMed Web of Science ®Google Scholar
• Su, M.T., Lin, S.H., & Chen, Y.C. (2011). Genetic association studies of angiogenesis- and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis. Human Reproduction Update, 17, 803–812.
   PubMed Web of Science ®Google Scholar
• Suryanarayana, V., Rao, L., Kanakavalli, M., Padmalatha, V., Deenadayal, M., & Singh, L. (2006). Recurrent early pregnancy loss and endothelial nitric oxide synthase gene polymorphisms. Archives of Gynecology and Obstetrics, 274, 119–124.
   Google Scholar
• Suzumori, N. & Sugiura-Ogasawara, M. (2010). Genetic factors as a cause of miscarriage. Current Medicinal Chemistry, 17, 3431–3437.
   PubMed Web of Science ®Google Scholar
• Tanus-Santos, J.E., Desai, M., & Flockhart, D.A. (2001). Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants. Pharmacogenetics, 11, 719–725.
   PubMedGoogle Scholar
• Yetik-Anacak, G. & Catravas, J.D. (2006). Nitric oxide and the endothelium: history and impact on cardiovascular disease. Vascular Pharmacology, 45, 268–276.
   PubMed Web of Science ®Google Scholar
• Yoshimura, T., Yoshimura, M., Tabata, A., Shimasaki, Y., Nakayama, M., Miyamoto, Y., et al. (2000). Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with severe preeclampsia. Journal of the Society for Gynecologic Investigation, 7, 238–241.
   PubMedGoogle Scholar
• Zammiti, W., Mtiraoui, N., & Mahjoub, T. (2008). Lack of consistent association between endothelial nitric oxide synthase gene polymorphisms, homocysteine levels and recurrent pregnancy loss in Tunisian women. American Journal of Reproductive Immunology, 59, 139–145.
   PubMed Web of Science ®Google Scholar