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Human Fertility
an international, multidisciplinary journal dedicated to furthering research and promoting good practice
Volume 17, 2014 - Issue 3
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Review Article

‘The BRCA Clock is Ticking!’: Negotiating medical concerns and reproductive goals in preimplantation genetic diagnosis

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Pages 159-164 | Received 15 Jul 2013, Accepted 17 Jan 2014, Published online: 08 Aug 2014

References

  • Antoniou, A., Pharoah, P.D., Narod, S., Risch, H.A., Eyfjord, J.E., Hopper, J.L., et al. (2003). Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies. American Journal of Human Genetics, 72, 1117–1130.
  • Charmaz, K. (2006). Constructing Grounded Theory: A Practical Guide Through Qualitative Qnalysis. Thousand Oaks: Sage.
  • Donnelly, L.S., Watson, M., Moynihan, C., Bancroft, E., Evans, D.G.R., Eeles, R., et al.(2013). Reproductive decision-making in young female carriers of a BRCA mutation. Human Reproduction, 28, 1006–1012. doi:10.1093/humrep/des441
  • Ehrich, K., & Williams, C. (2010). A ‘healthy baby’: the double imperative of preimplantation genetic diagnosis. Health, 14, 41–56.
  • Franklin, S., & Roberts, C. (2006). Born and Made: An Ethnography of Preimplantation Genetic Diagnosis. Princeton, New Jersey: Princeton University Press.
  • Gilbert, D.T., Killingsworth, M.A., Eyre, R.N., & Wilson, T.D. (2009). The surprising power of neighborly advice. Science, 323, 1617–1619.
  • Hallowell N. (2006). Varieties of suffering: living with risk of ovarian cancer. Health Risk & Society, 8, 9–26.
  • Hinyard, L., & Kreuter, M. (2007). Using narrative communication as a tool for health behavior change: a conceptual, theoretical, and empirical overview. Health, Education, & Behavior, 34, 777–792.
  • Hurley, K., Rubin, L., Werner-Lin, A., Sagi, M., Kemel, Y., Stern, R., et al. (2012). Incorporating information regarding preimplantation genetic diagnosis into discussions concerning testing and risk management for BRCA1/2 mutations: a qualitative study of patient preferences. Cancer, 118, 6270–6277.
  • King, M.C., Marks, J.H., Mandell, J.B., & New York Breast Cancer Study Group. (2003). Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science, 302, 643–646.
  • Krahn T. (2009). Preimplantation genetic diagnosis: does age of onset matter (anymore)?Medicine, Health Care and Philosophy, 12, 187–202.
  • Leide, A., Karlan, B.Y., & Narod, S.A. (2004). Cancer risks of male carriers of germline mutations in BRCA1 or BRCA2: A review of the literature. Journal of Clinical Oncology, 22, 735–742.
  • Meisel, Z.F., & Karlawish, J. (2011). Narrative vs. evidence-based medicine- and, not or. JAMA, 306, 2022–2023.
  • National Cancer Institute. (2013). BRCA1 and BRCA2: Cancer risk and genetic testing. Retrieved from: http://www.cancer.gov/cancertopics/factsheet/Risk/BRCA. Accessed January 17, 2014.
  • Noble, R. (2008). Pandora's box: ethics of PGD for inherited risk of late-onset disorders. Reproductive Biomed Online, 17, 55–60.
  • Ormondroyd, E., Donnelly, L., Moynihan, C., Savona, C., Bancroft, E., Evans D.G., et al. (2012). Attitudes to reproductive genetic testing in women who had a positive BRCA test before having children: a qualitative analysis. European Journal of Human Genetics, 20, 4–10.
  • Quinn, G.P., Pal, T., Murphy, D., Vadaparampil, S.T., & Kumar A. (2012). High-risk consumers’ perceptions of preimplantation genetic diagnosis for hereditary cancer: a systematic review and meta-analysis. Genetics in Medicine, 14, 191–200.
  • Rapp, R. (1999). Testing Women, Testing the Fetus: the Social Impact of Amniocentesis in America. New York, NY: Routledge.
  • Struewing, J.P., Hartge, P., Wacholder, S., Baker, S.M., Berlin, M., McAdams, M., et al. (1997). The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews. New England Journal of Medicine, 336, 1401–1408.
  • Stake, R.E. (1995). The Art of Case Study Research. Thousand Oaks, CA: Sage.
  • Tai, Y.C., Domchek, S., Parmigiani, G., & Chen, S. (2007)Breast cancer research among male BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institute, 99, 1811–1814.
  • Wang, C.W., & Hui, E.C. (2009). Ethical, legal and social implications of prenatal and preimplantation genetic testing for cancer susceptibility. Reproductive Biomedicine Online, 19, 23–33.
  • Werner-Lin, A. (2008). Beating the biological clock: the compressed family life cycle of young women with BRCA gene alterations. Social Work in Health Care, 47, 416–437.
  • Werner Lin, A., Rubin, L.R., Doyle, M., Stern, R., Savin, K., Hurley, K., & Sagi, M. (2012). ‘My funky genetics’: BRCA1/2 mutation carriers’ understanding of genetic inheritance and reproductive merger in the context of reprogenetic technologies. Families, Systems, & Health, 30, 166–180.

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